الصفحة 1
الصفحة 1
Oncogenes Meet Metabolism : From Deregulated Genes to a Broader Understanding of Tumour Physiology
In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg’s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effects on metabolism with the help of modern analytic technologies to rapidly analyze broad varieties of metabolites in various tissues and bodyfluids (metabonomics).
Minimally Invasive Tumor Therapies
In the age of the World Wide Web, informed patients continue to surprise oncologists with detailed questions about popular tumor therapies. Although minimally invasive tumor therapies (MITT) have become daily clinical practice for palliative treatment of liver tumors, the acceptance of these palliative modalities still varies enormously. In addition, promising results have been published for in situ ablation of lung metastases, bone tumors, and renal cell carcinoma. This book gives an up-to-date overview of the popular techniques and clinical results of MITT, with a clarification of the actual indications including the size, tumor entities, and clinical benefits. Moreover, the book focuses on the prospectives and limitations of imaging methods - ultrasound, computed tomography, and magnetic resonance imaging - used for MITT.
Metabolome Analyses : Strategies for Systems Biology
Metabolome Analyses is intended as a follow-up to Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis (Kluwer, 2003). That text offered guidelines to currently available technology, bioinformatics and databases. Evidence was presented showing metabolic profiling as a valuable addition to genomics and proteomics strategies devoted to drug discovery and development. This book focuses on how metabolic profiling is being more comprehensively integrated with the other "omics" technologies. It provides more practical applications of such "panomics" or "Systems Biology" approaches. The expanding use of mass spectrometry as a measurement technology in metabolic profiling is addressed through demonstrated applications. The integration of metabolic profiling and proteomics is probably most developed for plant-based studies, which was not addressed in Volume 1. Other areas related to metabolic profiling continue to show significant development. These include database strategies and an increased acceptance by the pharmaceutical industry of metabolic profiling. Also covered is the use of in silico metabolic networks. Again the focus is primarily on the pharmaceutical industry but the importance of metabolic profiling to studies on human nutrition (a burgeoning area) is discussed.
Intelligent data engineering and automated Learning - IDEAL 2006 ; 7th International Conference, Burgos, Spain, September 20-23, 2006, Proceedings
This volume of Lecture Notes in Computer Science contains accepted - pers presented at IDEAL 2006 held at the University of Burgos, Spain, during, September 20–23, 2006. The conference received 557 submissions from over 40 countriesaroundtheworld,whichweresubsequentlyrefereedbytheProgramme Committeeandmanyadditionalreviewers.Afterrigorousreview,170top-quality papers were accepted and included in the proceedings. The acceptance rate was only 30%, which ensured an extremely high-quality standard of the conference. The buoyant number of submitted papers is a clear proof of the vitality and increased importance of the ?elds related to IDEAL, and is also an indication of the rising popularity of the IDEAL conferences.
Innovative Learning Environments in STEM Higher Education : Opportunities, Challenges, and Looking Forward
As explored in this book, higher education in STEM fields is influenced by many factors, including education research, government and school policies, financial considerations, technology limitations, and acceptance of innovations by faculty and students.
Information Security Practice and Experience ; Vol. 3439 : 1st International Conference, ISPEC 2005, Singapore, April 11-14, 2005, Proceedings
As applications of information security technologies become pervasive, issues pertaining to their deployment and operation are becoming increasingly important. ISPEC is intended to be an annual conference that brings together researchers and practitioners to provide a con?uence of new information se- rity technologies, their applications and their integration with IT systems in various vertical sectors. The Program Committee consisted of leading experts in the areas of information security, information systems, and domain experts in applications of IT in vertical business segments. The topics of the conference covered security applications and case studies, access control, network security, data security, secure architectures, and cryp- graphic techniques. Emphasis was placed on the application of security research to meet practical user requirements, both in the paper selection process and in the invited speeches. Acceptance into the conference proceedings was very competitive. The Call for Papers attracted more than 120 submissions, out of which the Program Committee selected only 35 papers for inclusion in the proceedings.
Information Security ; Vol. 4176 ; 9th International Conference; ISC 2006, Samos Island, Greece, August 30 - September 2, 2006, Proceedings
th This volume contains the papers presented at the 9 Information Security Conference (ISC 2006) held on Samos Island, Greece, during August 30 – September 2, 2006. The Conference was organized by the University of the Aegean, Greece. ISC was first initiated as a workshop, ISW in Japan in 1997, ISW 1999 in Mal- sia, ISW 2000 in Australia and then changed to the current name ISC when it was held in Spain in 2001 (ISC 2001). The latest conferences were held in Brazil (ISC 2002), UK (ISC 2003), USA (ISC 2004), and Singapore (ISC 2005). ISC 2006 provided an international forum for sharing original research results and application experiences among specialists in fundamental and applied problems of - formation security. In response to the Call for Papers, 188 papers were submitted. Each paper was - viewed by three members of the PC, on the basis of their significance, novelty, and technical quality. Of the papers submitted, 38 were selected for presentation, with an acceptance rate of 20%.
Information Retrieval Technology ; Vol. 3689 ; 2nd Asia information retrieval symposium, AIRS 2005, Jeju Island, Korea, October 13-15, 2005, Proceedings
Asia Information Retrieval Symposium (AIRS) was established in 2004 by the Asian information retrieval community after the successful series of Information Retrieval with Asian Languages (IRAL) workshops held in six different locations in Asia, starting from 1996. The AIRS symposium aims to bring together international researchers and developers to exchange new ideas and the latest results in the field of information retrieval (IR). The scope of the symposium covers applications, systems, technologies and theoretical aspects of information retrieval in text, audio, image, video and multi-media data. We are very pleased to report that we saw a sharp and steady increase in the number of submissions and their qualities, compared with previous IRAL workshop series. We received 136 submissions from all over the world including Asia, North America, Europe, Australia, and even Africa, from which 32 papers (23%) were presented in oral sessions and 36 papers in poster sessions (26%). We also held a special session called “Digital Photo Albuming,” where 4 oral papers and 3 posters were presented. It was a great challenge and hard work for the program committee to select the best among the excellent papers. The high acceptance rates witness the success and stability of the AIRS series. All the papers and posters are included in this LNCS (Lecture Notes in Computer Science) proceedings volume, which is S- indexed. The technical program included two keynote talks by Prof. Walter Bender and Prof.
Information retrieval technology ; Vol. 3411 ; Asia information retrieval symposium, AIRS 2004, Beijing, China, October 18-20, 2004. Revised Selected Papers
TheAsiaInformationRetrievalSymposium(AIRS)wasestablishedbytheAsian information retrieval community after the successful series of Information - trieval with Asian Languages (IRAL) workshops held in six di?erent locations in Asia, starting from 1996. While the IRAL workshops had their focus on inf- mation retrieval problems involving Asian languages, AIRS covers a wider scope of applications, systems, technologies and theory aspects of information retrieval in text, audio, image, video and multimedia data. This extension of the scope re?ects and fosters increasing research activities in information retrieval in this region and the growing need for collaborations across subdisciplines. We are very pleased to report that we saw a sharp increase in the number of submissions and their quality, compared to the IRAL workshops. We received 106papersfromninecountriesinAsiaandNorthAmerica,fromwhich28papers (26%) were presented in oral sessions and 38 papers in poster sessions (36%). It was a great challenge for the Program Committee to select the best among the excellent papers. The low acceptance rates witness the success of this year’s conference. After a long discussion between the AIRS 2004 Steering Committee and Springer, the publisher agreed to publish our proceedings in the Lecture Notes in Computer Science (LNCS) series, which is SCI-indexed. We feel that this strongly attests to the excellent quality of the papers.
Individual differences in sensory and consumer science : Experimentation, analysis and interpretation
Individual differences in sensory and consumer science: Experimentation, Analysis and Interpretation presents easily readable, State-of-the-art coverage on how to plan and execute experiments that give rise to individual differences, Also providing the framework for successful analysis and interpretation of results. The book highlights the different methodologies that can be applied and how to select the correct methodology based on the type of study you are performing, Be it product research and development, Quality control or consumer acceptance studies.Written by an experienced team of statisticians and sensory and consumer scientists, The book provides both academics and industry professionals with the first complete overview of a topic of ever-increasing importance.
How to engineer software : A model-based approach
The book promotes development scalability through domain partitioning and subdomain partitioning. It also explores software documentation that specifically and intentionally adds value for development and maintenance. Contains many illustrative examples of model-based software engineering, from semantic model all the way to executable code Explains how to derive verification (acceptance) test cases from a semantic model Describes project estimation, along with alternative software development and maintenance processes Shows how to develop and maintain cost-effective software that solves real-world problems
Handbook of Homework Assignments in Psychotherapy : Research, Practice, and Prevention
The Handbook of Homework in Psychotherapy is the first resource for the practicing clinician that addresses the role of homework across major therapeutic paradigms and complex clinical problems. It opens with a series of practice-orientated chapters on the role of homework in different psychotherapies (acceptance and commitment, client-centered, constructivist, cognitive-behavioral, experiential, family, interpersonal, psychodynamic) written by an international team of expert psychotherapy practitioner-researchers. Then, experienced practitioners present strategies, examples, and formulated assignments for use with different populations (couples, families, older adults) and complex problems (chronic depression, chronic pain, eating disorders, obsessions and compulsions, personality disorders, psychosis, sexual dysfunction, substance abuse, traumatic brain injury). The Handbook closes with three chapters by leading psychotherapy theoreticians, researchers, and practitioners that critique the available research evidence for homework, integrate the recommendations for using homework in practice, and also provide directions for homework's role in prevention.
Grid and cooperative computing - GCC 2005 ; 4th International Conference, Beijing, China, November 30 -- December 3, 2005, Proceedings
This volume presents the accepted papers for the 4th International Conference on Grid and Cooperative Computing (GCC2005),held in Beijing, China, during November 30 – December 3, 2005.The conferenceseries of GCC aims to provide an international forum for the presentation and discussion of research trends on the theory, method, and design of Grid and cooperative computing as well as their scienti?c, engineering and commercial applications. It has become a major annual event in this area. The First International Conference on Grid and Cooperative Computing (GCC2002) received 168 submissions. GCC 2003 received 550 submissions, from which 176 regular papers and 173 short papers were accepted. The acceptance rate of regular papers was 32%, and the total acceptance rate was 64%. GCC 2004 received 427 main-conference submissions and 154 workshop submissions. The main conference accepted 96 regular papers and 62 short papers. The - ceptance rate of the regular papers was 23%. The total acceptance rate of the main conference was 37%. For this conference, we received 576 submissions. Each was reviewed by two independent members of the International Program Committee. After carefully evaluating their originality and quality, we accepted 57 regular papers and 84 short papers. The acceptance rate of regular papers was 10%. The total acc- tance rate was 25%.
Global perspectives on recognising non-formal and Informal Learning : Why recognition matters
This book deals with the relevance of recognition and validation of non-formal and informal learning in education and training, the workplace and society. In an increasing number of countries, it is at the top of the policy and research agenda ranking among the possible ways to redress the glaring lack of relevant academic and vocational qualifications and to promote the development of competences and certification procedures which recognise different types of learning, including formal, non-formal and informal learning. The aim of the book is therefore to present and share experience, expertise and lessons in such a way that enables its effective and immediate use across the full spectrum of country contexts, whether in the developing or developed world. It examines the importance of meeting institutional and political requirements that give genuine value to the recognition of non-formal and informal learning; it shows why recognition is important and clarifies its usefulness and the role it serves in education, working life and voluntary work; it emphasises the importance of the coordination, interests, motivations, trust and acceptance by all stakeholders.
Fuzzy systems and knowledge discovery ; Vol. 3614 ; 2nd International Conference, FSKD 2005, Changsha, China, August 27-29, 2005, Proceedings, Part II
This book and its sister volume, LNAI 3613 and 3614, constitute the proce- ings of the Second International Conference on Fuzzy Systems and Knowledge Discovery (FSKD 2005), jointly held with the First International Conference on Natural Computation (ICNC 2005, LNCS 3610, 3611, and 3612) from - gust 27–29, 2005 in Changsha, Hunan, China. FSKD 2005 successfully attracted 1249 submissions from 32 countries/regions (the joint ICNC-FSKD 2005 received 3136 submissions). After rigorous reviews, 333 high-quality papers, i. e. , 206 long papers and 127 short papers, were included in the FSKD 2005 proceedings, r- resenting an acceptance rate of 26. 7%. The ICNC-FSKD 2005 conference featured the most up-to-date research - sults in computational algorithms inspired from nature, including biological, e- logical, and physical systems. It is an exciting and emerging interdisciplinary area in which a wide range of techniques and methods are being studied for dealing with large, complex, and dynamic problems. The joint conferences also promoted cross-fertilization over these exciting and yet closely-related areas, which had a signi?cant impact on the advancement of these important technologies. Speci?c areas included computation with words, fuzzy computation, granular com- tation, neural computation, quantum computation, evolutionary computation, DNA computation, chemical computation, information processing in cells and tissues, molecular computation, arti?cial life, swarm intelligence, ants colony, arti?cial immune systems, etc. , with innovative applications to knowledge d- covery, ?nance, operations research, and more.
Fuzzy systems and knowledge discovery ; Vol. 3613 ; 2nd International Conference, FSKD 2005, Changsha, China, August 27-29, 2005, Proceedings, Part I
This book and its sister volume, LNAI 3613 and 3614, constitute the proce- ings of the Second International Conference on Fuzzy Systems and Knowledge Discovery (FSKD 2005), jointly held with the First International Conference on Natural Computation (ICNC 2005, LNCS 3610, 3611, and 3612) from - gust 27–29, 2005 in Changsha, Hunan, China. FSKD 2005 successfully attracted 1249 submissions from 32 countries/regions (the joint ICNC-FSKD 2005 received 3136 submissions). After rigorous reviews, 333 high-quality papers, i. e. , 206 long papers and 127 short papers, were included in the FSKD 2005 proceedings, r- resenting an acceptance rate of 26. 7%. The ICNC-FSKD 2005 conference featured the most up-to-date research - sults in computational algorithms inspired from nature, including biological, e- logical, and physical systems. It is an exciting and emerging interdisciplinary area in which a wide range of techniques and methods are being studied for dealing with large, complex, and dynamic problems. The joint conferences also promoted cross-fertilization over these exciting and yet closely-related areas, which had a signi?cant impact on the advancement of these important technologies. Speci?c areas included computation with words, fuzzy computation, granular com- tation, neural computation, quantum computation, evolutionary computation, DNA computation, chemical computation, information processing in cells and tissues, molecular computation, arti?cial life, swarm intelligence, ants colony, arti?cial immune systems, etc. , with innovative applications to knowledge d- covery, ?nance, operations research, and more.
Fundamental approaches to software engineering ; Vol. 3442 ; 8th International Conference, FASE 2005, Held as Part of the Joint European conferences on theory and practice of software, ETAPS 2005, Edinburgh, UK, April 4-8, 2005, Proceedings
ETAPS 2005 was the eighth instance of the European Joint Conferences on Theory and Practice of Software. ETAPS is an annual federated conference that was established in 1998 by combining a number of existing and new conf- ences. This year it comprised ?ve conferences (CC, ESOP, FASE, FOSSACS, TACAS), 17 satellite workshops (AVIS, BYTECODE, CEES, CLASE, CMSB, COCV, FAC, FESCA, FINCO, GCW-DSE, GLPL, LDTA, QAPL, SC, SLAP, TGC, UITP), seven invited lectures (not including those that were speci?c to the satellite events), and several tutorials. We received over 550 submissions to the ?ve conferences this year, giving acceptance rates below 30% for each one. The events that comprise ETAPS address various aspects of the system - velopment process, including speci?cation, design, implementation, analysis and improvement. The languages, methodologies and tools which support these - tivities are all well within its scope. Di?erent blends of theory and practice are represented, with an inclination towards theory with a practical motivation on the one hand and soundly based practice on the other. Many of the issues involved in software design apply to systems in general, including hardware s- tems,andtheemphasisonsoftwareisnotintendedtobeexclusive.
Fundamental approaches to software engineering ; 11th International Conference, FASE 2008, Held as Part of the Joint European conferences on theory and practice of software, ETAPS 2008, Budapest, Hungary, March 29-April 6, 2008. Proceedings
The fve main conferences received 571 submissions, 147 of which were accepted, giving an overall acceptance rate of less than 26%, with each conference below 27%.Congratulationsthereforetoallthe authorswhomadeittothe alprogramme! I hope that most of the other authors will still have found a way of participating in this exciting event, and that you will all continue submitting to ETAPS and contributing to make of it the best conference in the area،The events that comprise ETAPS address various aspects of the system velopment process,including specifcation, design, implementation, analysis and improvement.
Functional imaging and modeling of the heart ; 3rd International workshop, FIMH 2005, Barcelona, Spain, June 2-4, 2005, Proceedings
The FIMH conference was the ?rst attempt to agglutinate researchers from several complementary but often i- lated ?elds: cardiac imaging, signal and image processing, applied mathematics and physics, biomedical engineering and computer science, cardiology, radi- ogy, biology, and physiology. In the ?rst two editions, the conference received an enthusiastic acceptance by experts of all these communities. FIMH was ori- nally started as a European event and has increasingly attracted more and more people from the US and Asia. This edition of FIMH received the largest number of submissions so far with a result of 47 papers being accepted as either oral presentations or posters. There were a number of submissions from non-EU institutions which con?rms the growing interest in this series of meetings. All papers were reviewed by up to four reviewers. The accepted contributions were organized into 8 oral sessions and 3 poster sessions complemented by a number of invited talks. This year we tried to allocate as many papers as possible as oral presentations to facilitate more active participation and to stimulate multidisciplinary discussions.
Foundations of software science and computational structures ; Vol.3441 : 8th International Conference, FOSSACS 2005, Held as part of the joint European conferences on theory and practice of software, ETAPS 2005
ETAPS 2005 was the eighth instance of the European Joint Conferences on Theory and Practice of Software. ETAPS is an annual federated conference that was est- lished in 1998 by combining a number of existing and new conferences. This year it comprised ?ve conferences (CC, ESOP, FASE, FOSSACS, TACAS), 17 satellite wo- shops (AVIS, BYTECODE, CEES, CLASE, CMSB, COCV, FAC, FESCA, FINCO, GCW-DSE, GLPL, LDTA, QAPL, SC, SLAP, TGC, UITP), seven invited lectures (not including those that were speci?c to the satellite events), and several tutorials. We - ceived over 550 submissions to the ?ve conferences this year, giving acceptance rates below 30% for each one. Congratulations to all the authors who made it to the ?nal program! I hope that most of the other authors still found a way of participating in this exciting event and I hope you will continue submitting. The events that comprise ETAPS address various aspects of the system devel- ment process, including speci?cation, design, implementation, analysis and impro- ment. The languages, methodologies and tools which support these activities are all well within its scope.
