الصفحة 1
الصفحة 1
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New Vision of Metformin in treating cancer

The anti-diabetic drug metformin is rapidly emerging as a potential anticancer agent. Metformin is a biguanide that is effective in treating type 2 diabetes and the insulin resistance syndromes, improves insulin resistance by reducing hepatic gluconeogensis and by enhancing glucose uptake by skeletal muscle. Metformin can reduce the incidence of cancers and can reduce the mortality from cancers, increase the response to treatment cancer cells when using radiotherapy and chemotherapy, reduce the likelihood of relapse. Diabetes can be a factor in the occurrence of various types of cancer, and develop a variety of cancers such as colo-rectal, pancreas and liver cancers, compared to non-diabetic patients. Incidence of various cancers is high among patients of T2DM due to insulin resistance and mitogenic effects caused by hyperglycemia.

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Nanoscale Assembly : Chemical Techniques

Recent advances have pushed the limits of lithography firmly into the sub-100 nm domain, with smallest feature sizes around 10 nm. However, compared to living organisms, devices fabricated using nanolithography are not nearly as complex, as they are essentially 2D and contain only a limited number of chemical elements. For centuries, Nature has been a major inspiration for science. First of all to learn how Life functions at cellular level, but increasingly, as a blueprint for designing non-natural devices where the building blocks and their assembly are inspired by biological examples. The key tool in translating these examples into the domain of engineering, has been self-assembly or self-organization. This book gathers a spectrum researchers who have not only furthered our knowledge of self-assembly using small molecules, polymers and colloidal particles as building blocks, but who have also shown it to be a practical tool in the assembly of an astonishing variety of devices, ranging from molecular electronics to biosensors.

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Multimodal Technologies for Perception of Humans ; International Evaluation Workshops CLEAR 2007 and RT 2007, Baltimore, MD, USA, May 8-11, 2007, Revised Selected Papers

This book constitutes the thoroughly refereed joint post-workshop proceedings of two co-located events: the Second International Workshop on Classification of Events, Activities and Relationships, CLEAR 2007, and the 5th Rich Transcription 2007 Meeting Recognition evaluation, RT 2007, held in succession in Baltimore, MD, USA, in May 2007.The workshops had complementary evaluation efforts; CLEAR for the evaluation of human activities, events, and relationships in multiple multimodal data domains; and RT for the evaluation of speech transcription-related technologies from meeting room audio collections.

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Multimodal Technologies for Perception of Humans ; 1st International Evaluation Workshop on Classification of Events, Activities and Relationships, CLEAR 2006, Southampton, UK, April 6-7, 2006, Revised Selected Papers

This book constitutes the thoroughly refereed post-proceedings of the First International CLEAR 2006 Evaluation Campaign and Workshop on Classification of Events, Activities and Relationships for evaluation of multimodal technologies for the perception of humans, their activities and interactions. The workshop was held in the UK in April 2006.

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Mobile 3D Graphics

Historically, not enough was understood about how to deliver a high quality playing experience on handheld, small screen, small memory devices, plus there has been considerable confusion about the hardware’s abilities and restrictions. By addressing these issues this book provides: • A comprehensive explanation of 3D mobile graphics programming • Includes an extensive range of code samples in both C and Java • Combines 3D and 2D mobile graphics methods • Covers recent advances in mobile computer graphics techniques and applications. The book teaches fundamental 3D mobile graphics programming with standard APIs, and covers the basic and advanced application programme interfaces behind the major wireless and mobile devices supporting 3D graphics applications. Advanced undergraduates and postgraduates, as well as mobile application and games developers, will find this an excellent reference source.

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Introduction to Computer Graphics : Using Java 2D and 3D

This book introduces the most important basic concepts of computer graphics, coupling the technical background and theory with practical examples and applications throughout. Its user-friendly approach enables the reader to gain understanding through the theory at work, via the many example programs provided. With only elementary knowledge of the programming language Java, the reader will be able to create their own images and animations immediately, using Java 2D and/or Java 3D.

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Introduction to blender 3.0 : Learn organic and architectural modeling, lighting, materials, painting, rendering, and compositing with blender

Explains modeling, materials, lighting, painting, and more with Blender and other external tools. You will configure a 3D architectural environment and set up the workflow of an art and design project within Blender. You will use Blender's main tools—mesh modeling and sculpting—to create virtual objects and environments. And, you will explore building materials and light scenes, followed by drawing and virtual painting. Chapters cover rendering scenes and transforming them into 2D images or videos. You will learn to use Blender 3.0 for video editing as a compositor and video sequence editor (VSE or sequencer) with a wide range of effects available through the nodal system. You Will Learn : Create objects and architectural buildings with different techniques of 3D modeling / Master creating an environment for your objects and how to light them / Determine how to create node materials and assign them to your Blender objects / Pick up UV unwrapping and texture painting / Get closer to painting and drawing in Blender / Render your scenes and create stunning videos

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Instability in Models Connected with Fluid Flows I

Instability in Models Connected with Fluid Flows I presents chapters from world renowned specialists. The stability of mathematical models simulating physical processes is discussed in topics on control theory, first order linear and nonlinear equations, water waves, free boundary problems, large time asymptotics of solutions, stochastic equations, Euler equations, Navier-Stokes equations, and other PDEs of fluid mechanics. Fields covered include: controllability and accessibility properties of the Navier- Stokes and Euler systems, nonlinear dynamics of particle-like wavepackets, attractors of nonautonomous Navier-Stokes systems, large amplitude monophase nonlinear geometric optics, existence results for 3D Navier-Stokes equations and smoothness results for 2D Boussinesq equations, instability of incompressible Euler equations, increased stability in the Cauchy problem for elliptic equations.

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Image Processing in Radiology : Current Applications

Few fields have witnessed such impressive advances as image processing in radiology. The progress achieved has revolutionized diagnosis and greatly facilitated treatment selection and accurate planning of procedures. This book provides a comprehensive and up-to-date description of how to use 2D and 3D processing tools in clinical radiology.

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High Performance Tensegrity-Inspired Metamaterials and Structures

New metamaterials, smart materials and structures, and adaptive systems with adjustable behaviour or which use high performance or 'extremal' materials can be applied to bigger structural systems, such as cellular tensegrity lattices with extremal mechanical properties. Numerical analyses justify tensegrities and discrete and continuum models offer two main approaches to the analysis of tensegrity-based mechanical metamaterials and lattices. Two examples of 2D and 3D tensegrity modules and lattices, and potential applications in civil engineering are presented.

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Hearing faces

Our project aims to aid deaf-mute people by tracking hand movements of the deaf-mute person for word level American Sign Language using WLASL model that include 2D CNN -3D CNN and RNN networks training on WLASL large video dataset, then generating the corresponding text and analyzing the person's facial gestures to generate information related to the tone of voice that is most appropriate to the person's age, gender, and race through MTCNN network algorithm that training on generated dataset by us depending on blending VOXCELEB dataset and VGGFACE dataset .

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Galaxy Formation

This second edition of Galaxy Formation is an up-to-date text on astrophysical cosmology, expounding the structure of the classical cosmological models from a contemporary viewpoint. This forms the background to a detailed study of the origin of structure and galaxies in the Universe. The derivations of many of the most important results are derived by simple physical arguments which illuminate the results of more advanced treatments. A very wide range of observational data is brought to bear upon these problems, including the most recent results from WMAP, the Hubble Space Telescope, galaxy surveys like the Sloan Digital Sky Survey and the 2dF Galaxy Redshift Survey, studies of Type 1a supernovae, and many other observations.

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From Cells to Proteins : Imaging Nature across Dimensions ; Proceedings of the NATO Advanced Study Institute, held in Pisa, Italy, 12-23 September 2004

This book offers updated information on how much information we are able to obtain in the exploration of the inner details of biological specimens in their native structure and composition. And deals with the implementation of laser beam and stage scanning systems incorporating confocal optics or multiphoton microscopy; the advent of new electro-optical detectors with great sensitivity, linearity, and dynamic range; the possibility of 2D fast image enhancement, reconstruction, restoration, analysis and 3D display, and the application of luminescence techniques.

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Essential NMR : For Scientists and Engineers

ESSENTIAL NMR is a set of lecture notes for scientists and engineers who want to brush up on their knowledge of NMR. This book is also a compendium for graduate and postgraduate students of physics and chemistry as well as for their teachers, covering all fields of NMR, i.e. NMR methodology and hardware, chemical analysis, 2D-spectroscopy, NMR imaging, flow NMR, and quality control NMR. The material, selected and organized for a one-semester course, is presented with pairs of pages addressing particular topics. One page of each pair provides a text containing the key information, the other page shows a color illustration. This is the most comprehensive textbook on NMR to date.

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DNA and RNA origami : methods and protocols

Detials diverse methodological approaches on the assembly and applications of DNA origami assemblies. Chapters guide readers through different synthetic and computational methods, isolation and structural characterization of 2D and 3D DNA origami nanoarchitectures, nanophotonics, drug delivery, biophysics, and synthetic biology.Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

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Digital Sketching : Computer-Aided Conceptual Design

Delivers a comprehensive and insightful examination of how architects and other design professionals can best use digital design technology to become better designers. Celebrated professional, professor, and author John Bacus provides readers with practical and timely information on emerging digital design technologies and their effect on professional practice.

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Diabetes Mellitus & Recent developments

Diabetes mellitus is a group of metabolic disease characterized by hyperglycemia resulting from defect in insulin secretion, insulin action, or both. Symptoms of marked hyperglycemia include polyuria, polydipsia, weight loss, sometimes with polyphagia, and blurred vision. Frequency of diabetic in the world About 1 in 11 adults worldwide now have diabetes mellitus, 90% of whom have type 2 diabetes mellitus (T2DM). Asia is a major area of the rapidly emerging T2DM global epidemic Classification Of Diabetic Mellitus. 1-Type 1 diabetes: which accounts for only5–10% of those with diabetes, results from a cellular-mediated autoimmune destruction of the cells of the pancreas. 2-Type 2 diabetes: which accounts for90 –95% of those with diabetes, result from insulin resistance. The chronic complications of diabetes mellitus affect many organ systems and are responsible for the majority of morbidity and mortality. Such as, retinopathy, diabetic foot, neuropathy, and nephropathy, sexual dysfunction, and skin changes.

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Control Systems Theory and Applications for Linear Repetitive Processes

After motivating examples, this monograph gives substantial new results on the analysis and control of linear repetitive processes. These include further applications of the abstract model based stability theory which, in particular, shows the critical importance to the dynamics developed of the structure of the initial conditions at the start of each new pass, the development of stability tests and performance bounds in terms of so-called 1D and 2D Lyapunov equations. It presents the development of a major bank of results on the structure and design of control laws, including the case when there is uncertainty in the process model description, together with numerically reliable computational algorithms. Finally, the application of some of these results in the area of iterative learning control is treated --- including experimental results from a chain conveyor system and a gantry robot system.

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Launching the imagination : A comprehensive guide to two-dimensional design

Launching the Imagination treats design as both a verb and a noun—as both a process and a product. Through an immersion in 2D, 3D, and 4D concepts and possibilities, students develop visual thinking strategies that will serve them throughout their studies and their careers. They discover that design is deliberate—a process of exploring a wide range of solutions and choosing the most promising option for development. They are encouraged to analyze each resulting solution thoughtfully in order to produce the clearest and most inventive solution to each assignment.

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IUTAM symposium on relations of shell plate beam and 3D models ; Proceedings of the IUTAM Symposium on the relations of shell, plate, beam, and 3D models, Dedicated to the Centenary of Ilia Vekua’s Birth, held in Tbilisi, Georgia, April 23-27, 2007

Contains papers on the main topics reflecting the scientific programme of the symposium: hierarchical, refined mathematical and technical models of shells, plates, and beams; relation of 2D and 1D models to 3D linear, non-linear and physical models; junction problems. In particular, peculiarities of cusped shells, plates, and beams are emphasized and special attention is paid to junction, multibody and fluid-elastic shell (plate, beam) interaction problems and their applications.

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