الصفحة 9
الصفحة 9
Chemical and functional properties of food components
Described the contents of food raw materials and products, the chemistry/biochemistry of food components, as well as the changes occurring during post-harvest storage and processing affecting the quality of foods. Discusses the role of chemical compounds in the structure of raw materials and the formation of different attributes of food quality, including nutritional value, safety, and sensory properties. It contains four new chapters: “Non-Protein Nitrogenous Compounds”; “Prooxidants and Antioxidants in Food”; “Non-Nutritive Bioactive Compounds in Food of Plant Origin”; and “Analytical Methods Used for Assessing the Quality of Food Products.”
Chemical and clinical applications of tempol : A marvelous molecule
A comprehensive and authoritative exploration of Tempol (4-Hydroxy-TEMPO), an exceptional chemical compound with diverse applications in both scientific research and medical practice. This book delves into Tempol's unique properties, mechanisms of action, and its potential role in combating oxidative stress-related disorders. Includes a chapter devoted to the safe handling, storage, and disposal of Tempol in compliance with pharmaceutical regulations. The authors pay particular attention to pharmaceutical regulations in the industry.
Checkpoint Responses in Cancer Therapy
This book’s distinguished panel of authors takes a close look at topics ranging from the major molecular players affecting DNA synthesis and the response to DNA damage to advances made in the identification of chemical compounds capable of inhibiting individual mitotic kinases. Illuminating and authoritative, Checkpoint Responses in Cancer Therapy offers a critical summary of findings for researchers in the pharmaceutical and biotechnology industries and a valuable resource for academic scientists in cancer research and the study of cell-cycle regulation, signal transduction and apoptosis.
Chalcogenocarboxylic acid derivatives
Chalcogenocarboxylic acid derivatives are a large class of compounds including more than one chalcogenocarboxyl group in which one or two oxygen atoms of the carboxyl group are replaced with sulfur, selenium or tellurium atoms. The chemistry of metal chalcogenocarboxylates has not been explored extensively as that of carboxylates and dithiocarbamates. This volume presents a comprehensive overview of the syntheses and their limitations, structures and reactions of chalcogenocarboxylic acid derivatives, by emphasizing the developments in organic and inorganic chalcogen chemistry over the last 5 to 20 years.
Ceramic and Glass Materials : Structure, Properties and Processing
Ceramic and Glass Materials: Structure, Properties and Processing is a concise and comprehensive guide to the key ceramic and glass materials used in modern technology. Each chapter focuses on the structure-property relationships for these important materials and expands the reader’s understanding of their nature by simultaneously discussing the technology of their processing methods. In each case, the resulting understanding of the contemporary applications of the materials provides insights as to their future roles in twenty first century engineering and technology. Organized to be a practical and comprehensive resource, each chapter is dedicated to a specific material such as: alumina, mullite, sillimanite minerals, aluminates, quartz and silicas, refractory oxides, clays, concrete and cement, lead compounds, and zirconia.
Carotenoids ; Vol.4 : Natural Functions
The Carotenoids book series provides detailed accounts of the fundamental chemistry of carotenoids and the basic methods used in carotenoid research, and critical discussions of the biochemistry, functions and applications of these important compounds. Volume 4 and its companion, Volume 5, deal with the functions of carotenoids in all kinds of living organisms and the actions of carotenoids in human nutrition and health. The material presented in the earlier Volumes is all relevant to studies of biological functions and actions. In particular, biological studies must be supported by a rigorous analytical base. The various analytical procedures described in Volumes 1A and 1B, supplemented by the data for individual compounds given in the Carotenoids Handbook, must be understood and applied correctly, whether they are being used for quantitative analysis, identification or in complex studies of carotenoids in situ.
Biotechnology for the Future
One area that has attracted much attention is the use of cell factories for the production of a wide range of chemicals. This area illustrates very well the definition of biochemical engineering , and it has therefore been chosen as the focus of this volume. The use of cell factories for production of chemicals dates back to the production of penicillin, ethanol, acetone–butanol, glycerol and further to enzymes and other antibiotics. All these products were traditionally produced by cell factories that naturally produce these compounds. With the introduction of genetic engineering it has,This volume therefore contains chapters on concepts of metabolic engineering on detailed modeling of cellular systems
Biotechnology for Odor and Air Pollution Control
An international board of authors from universities, research institutes, and industries describe various biotechnological methods ranging from laboratory, to pilot evaluation and to full-scale process implementation. Topics include bioprocesses for the treatment of odors and air pollutants in wastewater treatment plants, rendering plants, chemical production facilities, and food and flavor manufacturing facilities. In addition to the basic microbiological and engineering aspects, the design, modeling and control of bioreactors are also presented.
Bioremediation of Soils Contaminated with Aromatic Compounds
Environmental biotechnology, which was in its infancy in the early 80's, has evolved thanks to the revolution brought about by molecular biology. Multiple successes in the biological cleanup of civil and industrial wastewater and of hydrocarbon soil pollution, demonstrate the vast power of clean technologies. In addition, the buildup of information on the activities of microorganisms as catalysts in all sorts of natural, industrial and animal environments has flourished. There is a continuing realization of the critical role of microbial processes in biological, industrial and geological systems. Since environmental biotechnology has matured, it is ready to tackle bigger challenges: the scaling up of many bioremediation systems still in progress, the search for novel biocatalysts for industrial applications, the continuing effort against common human life-threatening processes such as antibiotic resistance, the accumulation of hormone-mimicking substances (endocrine disrupters), the deposition of air-borne pesticides in the environment and, the degradation of recalcitrant contaminants. These endeavors will help prevent the contamination of food chains, protect human life and allow for human activity and economic development that do not compromise environmental sustainabijity.
Biomarkers in drug discovery and development : A handbook of practice, application, and strategy
Discusses biomarker characterization and validation and applications throughout drug discovery and development. Explains where proper use of biomarkers can substantively impact drug development timelines and costs, enable selection of better compounds and reduce late stage attrition, and facilitate personalized medicine. Helps readers get a better understanding of biomarkers and how to use them, for example which are accepted by regulators and which still non-validated and exploratory. Updates developments in genomic sequencing, and application of large data sets into pre-clinical and clinical testing; and adds new material on data mining, economics, and decision making, personal genetic tools, and wearable monitoring. Includes case studies of biomarkers that have helped and hindered decision making
Biocombinatorial approaches for drug finding
Genome- and proteome-based research is generating a significant increase in the number of available drug targets. Correspondingly there is an increasing need for novel, diverse compounds, particularly based on natural compounds, as screening resource
Biochemistry and molecular biology of antimicrobial drug action
This stimulating new edition of the well-respected title Biochemistry and Molecular Biology of Antimicrobial Drug Action primarily covers medically important antimicrobial agents, but also includes some compounds not in current medical use which have been invaluable as research tools in biochemistry.
Biochemical Mechanisms of Detoxification in Higher Plants : Basis of Phytoremediation
Plants play a key role in purifying the biosphere of the toxic effects of industrial activity. This book shows how systematic application of the results of investigations into the metabolism of xenobiotics (foreign, often toxic substances) in plants could make a vastly increased contribution to planetary well-being. Deep physiological knowledge gained from an accumulation of experimental data enables the great differences between the detoxifying abilities of different plants for compounds of different chemical nature to be optimally exploited. Hence planting could be far more systematically adapted to actual environmental needs than is actually the case at present.
Bioactives and pharmacology of medicinal plants : Vol.1
Bioctives and Pharmacology of Medicinal Plants, concisely presents an abundance of important information on the bioactive and pharmacological properties of medicinal plants. It provides valuable comprehensive research and studies on bioactive phytocompounds of over 68 important medicinal plants with beneficial properties. For each species included in the volume, a brief introduction is given along with their bioactive compounds and chemical structures, followed by their chief pharmacological activities that include antiviral, antimicrobial, antioxidant, anti-cancer, anti-inflammatory, antidiabetic, hepatoprotective, nephroprotective, and cardioprotective activities. A review of the published literature on pharmacological activities on each species is included also, providing a thorough resource on each of the plants covered in the volume.
Bioactives and pharmacology of Legumes
A variety of bioactives and therapeutics from the legume family (Fabaceae or Leguminosae) are thoroughly detailed. For each species included in the volume, a brief introduction is given, the plant’s bioactive compounds are listed, and its chemical structures shown, followed by their pharmacological activities. Many of these plants have medicinal activities that include antiviral, antimicrobial, antioxidant, anticancer, anti-inflammatory, and antidiabetic, hepatoprotective, nephroprotective and cardioprotective. The biochemical characteristics of the 37 plants included, such as the type of starch, protein, and fibers, can be exploited as binders, excipients, thickeners, and dispersants in the formulation of various products in the pharmaceutical industry. The published literature on the pharmacological activities on each species is reviewed and presented in a concise and clear manner.
Bioactives and pharmacology of lamiaceae
Provides a wealth of information on plants in the Lamiaceae family, noted for their essential oils and bioactives and pharmacological properties. The chapters investigate a wide variety of species, providing for each an introduction, characteristics, properties, distribution, traditional uses, and current and potential pharmacological applications. Aiming to be a resource for the development of new drugs based on species within the Lamiaceae family, the volume discusses 26 species, including bungleweed (Ajuga), Malabar catmint (Anisomeles malabarica), beechwood (Gmelina arborea), Brazilian mint (Hyptis crenata), rosemary (Rosmarinus officinalis L.), holy basil (Ocimum tenuiflorum), and many more.
Bioactive Molecules and Medicinal Plants
Use of medicinal plants is as old as human civilization and continuous efforts are being made to improve medicinal plants or produce their products in high amounts through various technologies. About 200,000 natural products of plant origin are known and many more are being identifed from higher plants and microorganisms. Some plant-based drugs have been used for centuries and there is no alternative medicine for many drugs, such as cardiac glycosides. However, natural products research was sidelined to pave the way for com- natorial chemistry, which was expected to produce large numbers of synthetic compounds for high-throughput screening (HTS). This line of work has failed to deliver desirable results. Moreover, it is not possible for all pharmaceutical companies and institutions to adopt costly HTS technology. Therefore, medi- nal plants and their bioactive molecules are always in demand and are a central point of research. While planning this book, we endeavored to incorporate - ticles that cover the entire gamut of current medicinal plants research.
Bioactive Materials in Dentistry : Remineralization and Biomineralization
Addresses the use of different bioactive materials in dentistry, considering the performance of these biomaterials in the hard tissues of the tooth, and the response of the dental pulp, as well as the influence of the composition of these materials and of the individual’s systemic alterations in bioactivity and in antimicrobial activity. The several in vivo and in vitro tests to evaluate the bioactivity of a biomaterial will also be addressed.
Bioactive Marine Natural Products
Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R&D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.
Bioactive Heterocyles I
Bioactive Heterocycles I is a continuation of critical accounts about heterocyclic compounds within the series Topics in Heterocyclic Chemistry. The present volume provides comprehensive reviews of the chemistry and bioactivity of selected groups of heterocycles and natural products. … Overall, this book covers in detail several classes of bioactive heterocyclic compounds including selected natural products. The focus is on the most recent advances, and the clarity of the presentation is very good. It should be of interest to individuals interested in the discovery and synthesis of bioactive small molecules, including research scientists in academia and industry.
