الصفحة 9
الصفحة 9
Governance of automated decision-making and EU law
Presents a multifaceted exploration of the intersection between technological innovation and democratic governance in Europe. It rigorously examines the profound impact of information technologies on rule-making and decision-making processes, emphasizing the preservation of constitutional values within the European Union (EU). Simultaneously, the book seeks to devise future-proof regulatory strategies to navigate the challenges of rapid technological advancements.
Good laboratory practice for nonclinical studies
The GLP regulations have been enacted since 1978 and are currently under a proposed FDA amendment to revise terminology and accommodate other changes relating to advances in technology related to the industry. This book provides a unique opportunity to access interpretation of the 21CFR58 regulatory requirements from leading industry experts with a vast knowledge and expertise in their fields. The approach used takes the regulations, provides interpretations and references to examples and regulatory actions. Data integrity and the use of electronic systems in compliance with 21CFR11 Electronic Records: Electronic Signatures are also discussed.
Good laboratory practice : The why and the how
The GLP regulations have developed from rules on how to exactly document the planning, conduct and reporting of toxicity studies to a quality system for the management of a multitude of study types, from the simple determination of a physical/chemical parameter to the most complex field studies or ecotoxicology studies. At the same time the term “Good Laboratory Practice” has become somewhat of a slogan with the aim to characterise any reliably conducted laboratory work.
Golden gate cloning : Methods and protocols
Provides an overview of the latest protocols that cover the full range of in silico, in vitro, and in vivo approaches to help researchers plan, design, and perform Golden Gate cloning experiments. The chapters in this book cover topics such as Golden Gate cloning of standardized parts; modular DNA construct design for high-throughput Golden Gate Assembly; Golden Gate cloning of Synthetic CRISPR RNA spacer sequences; Golden Gate cloning in Actinobacteria; and YeastFab cloning of toxic genes and protein expression optimization in yeast.
Global RFID : The Value of the EPCglobal Network for Supply Chain Management
At the same time, I was a junior Brand Manager at Procter & Gamble w- ried about a much more mundane problem: how to keep my products on the shelf. Embedding RFID tags in the products, and RFID readers in the shelf, seemed like the perfect – indeed the only – way to do this. But I needed RFID to be cheaper, better, and standardized in an open system. In early 1999, by sheer chance, I met Brock and Sarma. The result was a potent meeting of minds. I was looking to fund research, and Brock, Sarma and Siu were looking for research funding. Working with Alan Haberman of the Uniform Code Council, one of the founding fathers of the UPC bar code, and Allan Boath of the Gillette C- pany, we developed a plan for a new industry funded research consortium at MIT.
Global optimization and constraint satisfaction ; 2nd International Workshop, COCOS 2003, Lausanne, Switzerland, Nevember 18-21, 2003, Revised Selected Papers
Theformulationofmanypracticalproblemsnaturallyinvolvesconstraintsonthe variables entering the mathematical model of a real-life situation to be analyzed. It is of great interest to ?nd the possible scenarios satisfying all constraints, and, iftherearemanyofthem,eitherto?ndthebestsolution,ortoobtainacompact, explicit representation of the whole feasible set. The 2nd Workshop on Global Constrained Optimization and Constraint S- isfaction, COCOS 2003, which took place during November 18–21, 2003 in L- sanne, Switzerland, was dedicated to theoretical, algorithmic, and application oriented advances in answering these questions. Here global optimization refers to ?nding the absolutely best feasible point, while constraint satisfaction refers to?ndingallpossiblefeasiblepoints.AsinCOCOS2002,the?rstsuchworkshop (see the proceeedings [1]), the emphasis was on complete solving techniques for problems involving continuous variables that provide all solutions with full rigor, and on applications which, however, were allowed to have relaxed standards of rigor.
Global Health Collaboration : Challenges and Lessons
Details the innovative work of the Pan Institution Network for Global Health in creating collaborative research-based answers to large-scale health issues. Equitable partnerships among member universities representing North America, Africa, Asia, and Europe reverse standard cross-national dynamics to develop locally relevant responses to health challenges as well as their underlying disparities. Case studies focusing on multiple morbidities and effects of urbanization on health illustrate open dialogue in addressing HIV, maternal/child health, diabetes, and other major concerns. These instructive examples model collaborations between global North and South as meaningful steps toward the emerging global future of public health.
Geosynthetics and their applications
Geosynthetics are being used extensively throughout the world as they offer the most efficient and cost-effective solutions of a myriad of civil engineering problems.If properly protected, geosynthetics have the potential of functioning for hundreds of years.Rational design methods - based on sound concepts and standardized text techniques for detemining the technical properties of geosynthetics - are now available, placing the use of geosynthetics on a firm base.
Geometric Data Analysis : From Correspondence Analysis to Structured Data Analysis
Geometric Data Analysis (GDA) is the name suggested by Stanford University to designate the approach to Multivariate Statistics initiated.as Correspondence Analysis, an approach that has become more and more used and appreciated over the years. This book presents the full formalization of GDA in terms of linear algebra - the most original and far-reaching consequential feature of the approach - and shows also how to integrate the standard statistical tools such as Analysis of Variance, including Bayesian methods. Chapter 9, Research Case Studies, is nearly a book in itself; it presents the methodology in action on three extensive applications, one for medicine, one from political science, and one from education (data borrowed from the Stanford computer-based Educational Program for Gifted Youth ). Thus the readership of the book concerns both mathematicians interested in the applications of mathematics, and researchers willing to master an exceptionally powerful approach of statistical data analysis.
Geometric and Engineering Drawing
Descriptive geometry and contemporary drafting guides the student through the essential principles to create engineering drawings that comply with international standards of technical product specification. This heavily updated new edition now applies to CAD as well as conventional drawing.
Geomatics Solutions for Disaster Management
Natural and anthropogenic disasters have caused a large number of victims and significant social and economic losses in the last few years. There is no doubt that the risk prevention and disaster management sector needs drastic measures and improvements in order to decrease damage and save lives of inhabitants. Effective utilization of satellite positioning, remote sensing, and GIS in disaster monitoring and management requires research and development in numerous areas: data collection, access and delivery, information extraction and analysis, management and their integration with other data sources (airborne and terrestrial imagery, GIS data, etc.), data standardization, organizational and legal aspects of sharing of remote sensing information. This book provides researchers and practitioners with a good overview of what is being developed in this topical area.
Genetic testing in reproductive medicine
Illustrates the importance and significance of molecular genetic testing in reproductive disorders. The present book covers the genetic testing in various reproductive system anomalies, including disorders of sexual development, male infertility (Y deletions, autosomal mutations, sperm DNA fragmentation), female infertility (PCOS and POF), mitochondrial DNA testing for oocyte quality, recurrent pregnancy loss, pre-term birth, endometrial receptivity, prenatal genetic screening, reproductive carrier screening, preimplantation genetic screening, endometrial cancer, cervical cancer and other related reproductive health disorders. Microbiome testing and its contribution to genetic testing in reproductive medicine are also discussed. Covers ethical, moral and technical challenges in genetic testing in reproductive medicine. The book aims to set up a standard with regard to genetic testing in the reproductive medicine field, encourage further data generation, and provide food for thought in the areas of lacunae.
Generalized Curvatures
The central object of this book is the measure of geometric quantities describing N a subset of the Euclidean space (E ,), endowed with its standard scalar product. Let us state precisely what we mean by a geometric quantity. Consider a subset N S of points of the N-dimensional Euclidean space E , endowed with its standard N scalar product. LetG be the group of rigid motions of E . We say that a 0 quantity Q(S) associated toS is geometric with respect toG if the corresponding 0 quantity Q[g(S)] associated to g(S) equals Q(S), for all g?G . For instance, the 0 diameter ofS and the area of the convex hull ofS are quantities geometric with respect toG . But the distance from the origin O to the closest point ofS is not, 0 since it is not invariant under translations ofS. It is important to point out that the property of being geometric depends on the chosen group. For instance, ifG is the 1 N group of projective transformations of E , then the property ofS being a circle is geometric forG but not forG , while the property of being a conic or a straight 0 1 line is geometric for bothG andG . This point of view may be generalized to any 0 1 subsetS of any vector space E endowed with a groupG acting on it.
General Principles of Tumor Immunotherapy : Basic and Clinical Applications of Tumor Immunology
Brings together the world’s leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated through both experimental clinical trials and review of current standard of care therapeutic agents. This information will be invaluable to both students of immunology and cancer research and practicing physicians who have patients with cancer. The book provides a comprehensive overview of the field, demonstrates how advances in basic immunology can and are being applied to cancer, and describes the current status of approved immunotherapy regimens.
Gastrointestinal Cancer
Gastrointestinal cancer includes cancer of the digestive system - the esophagus, colon, rectum, anus, liver, pancreas, and other digestive organs. Taken as a whole, there are an estimated 250,600 new cases in the US. Colon and rectum cancer is the third leading cause of cancer and cancer deaths in the US. Gastrointestinal Cancer is the third volume in the M.D. Anderson Cancer Care series, featuring the current standard approach to GI cancer care from the experts at M.D. Anderson Cancer Center. Designed for the practicing oncologist, this clinical guidebook allows for quick, authoritative access to the latest and best multimodality therapies. Topics covered in this volume include AJCC staging of gastrointestinal malignancies, recent advances in histopathology of gastroinestinal cancers, imaging techniques and endoscopy in the management of GI malignancies, colorectal cancer, liver cancer, gastric cancer, esophageal cancer, anal cancer, and palliative therapy. Each of the 20 chapters ends with an up-to-date list of suggested readings, as well as "key practice points" highlighting the most principles and practices of each chapter for at-a-glance reference. More than 80 illustrations complement the text. This thorough, practical volume is the essential clinical guide for the oncologists, surgeons, and all physicians involved in the care of patients with GI cancer.
Gaming, simulations and society : Research scope and perspective
The Japan Association of Simulation & Gaming (JASAG) and the Science Council of Japan (SCJ) hosted ISAGA 2003, the 34th annual conference of the International Simulation and Gaming Association (ISAGA), at Kazusa Akademia Park in Kisarazu, Japan,August 25–29, 2003. About 450 participants and guests attended,with 330 from Japan and 101 from 34 other countries. The number of submitted papers and reports exceeded 210, and in addition, many poster presentations and experiential sessions were held. This book is made up of 30 papers submitted to ISAGA 2003 and provides a good example of the diverse scope and standard of research achieved in simu- tion and gaming today.The theme of ISAGA 2003 was “Social Contributions and Responsibilities of Simulation and Gaming.”
Galaxies and How to Observe Them
Satisfies the need for a modern, comprehensive review in combining the three major aspects: the physical background on the nature and data of galaxies, the relevant instrumentation and viewing techniques, and finally the targets and their individual appearance in telescopes of various apertures. To illustrate the latter, a comprehensive sample of galaxies, including quasars, groups and clusters of galaxies is presented. This combination of theoretical knowledge and practical information guarantees successful observing sessions. The book could become a standard source on galaxy observing for all kinds of amateur observers, from the beginner to the experienced.
Funology : From usability to enjoyment
This book reflects the move in Human Computer Interaction studies from standard usability concerns towards a wider set of problems to do with fun, enjoyment, aesthetics and the experience of use. Traditionally HCI has been concerned with work and task based applications but as digital technologies proliferate in the home fun becomes an important issue. There is an established body of knowledge and a range of techniques and methods for making products and interfaces usable, but far less is known about how to make them enjoyable.
Fundamentals of risk management : Understanding, evaluating and implementing effective enterprise risk management
This book covers the key principles of risk management and how to deal with the different types of risk organizations face. The frameworks of business continuity planning, enterprise risk management, and project risk management are covered alongside an overview of international risk management standards and frameworks, strategy and policy.
Fundamentals of Relational Database Management Systems
Information is a valuable resource to an organization. Computer software provides an efficient means of processing information, and database systems are becoming an increasingly common means by which it is possible to store and retrieve information in an effective manner. This book provides comprehensive coverage of fundamentals of database management systems. This book is for those who wish a better understanding of relational data modeling, its purpose, its nature, and the standards used in creating relational data models.
