الصفحة 84
الصفحة 84
Enhancing the Dissolution Rate of Atorvastatin by Solid Dispersion Technique
In the last few decades, solid dispersion (SD) technology had been studied as an approach to produce an amorphous carrier to enhance the solubility, dissolution rate, and bioavailability of poorly water-soluble drugs. The use of suitable carrier and methodology in the preparation of SDs play a significant role in the biological behavior of the SDs. Atorvastatin is a statin group HMG-CoA reductase inhibitor drug that is commonly used to adverse cardiovascular events and to lower blood total cholesterol and LDL-cholesterol. the solubility of atorvastatin in water is very low (0.1 mg mL− 1), which results in reduced bioavailability. In order to enhance its solubility, we have prepared solid dispersions (SDs) of atorvastatin at different drug: polymer ratios (1:2, 1:10, 1:20,1:25 and 1:40), using polyethylene glycol 6000 as polymer and different preparation methods (co-precipitate and melting methods) The characterization of the SDs was performed using differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR) The solubility of AT was improved by the incorporation PEG6000.
Enhancing Smallholder Farmers' Access to Seed of Improved Legume Varieties Through Multi-stakeholder Platforms : Learning from the TLIII project Experiences in sub-Saharan Africa and South Asia
This book shares the experiences of Tropical Legumes III (TLIII) project in facilitating access to seed of improved legume varieties to smallholder farmers through innovation platforms. It highlights practices and guiding principles implemented in eight developing countries of sub-Saharan Africa and South Asia. This book details key processes that respective teams employed to create an innovation space that delivers seed, other inputs, knowledge and financial services to agricultural communities and most importantly, the underserved farmers in remote areas of the drylands
Enhancing future skills and entrepreneurship ; 3rd Indo-German conference on sustainability in engineering
This book presents the proceedings of the 3rd Indo-German Conference on Sustainability in Engineering held at Birla Institute of Technology and Science, Pilani, India, on September 16–17, 2019
Enhanced Radio Access Technologies for Next Generation Mobile Communication
Enhanced Radio Access Technologies for Next Generation Mobile Communication presents a comphrenhensive overview of the latest technology developments in the field Mobile Communications. This monograph focuses on the fundamentals of mobile communications technology and systems, including the history and service evolution of mobile communications and environments. Further to this, CDMA technology including spread spectrum, orthogonal and PN codes are introduced. Other important aspects include fundamentals of single carrier CDMA technologies, DS CDMA, Broadband CDMA with frequency domain equalizer, and multi-carrier CDMA technology for high speed data transmission including MC-DS/CDMA, MC-CDMA. Finally aspects of modern cellular systems such as cdma2000/1xEv-Do/1xEv-Dv and WCDMA/HSDPA are introduced and existing and developing wireless data services, such as Wi-Fi, Bluetooth, UWB, WiBro/Mobile WiMAX, and digital broadcasting services like DVB, DMB, ISDBT are described.
Enhanced Methods in Computer Security, Biometric and Artificial Intelligence Systems
"Methods of Artificial Intelligence and Intelligent Agents" contains 13 contributions analyzing such areas of AI as fuzzy set theory, predicate logic, neural networks, clustering, data mining and others. It also presents applications of AI as possible solutions for problems like firm bankruptcy, soil erosion, flight control and others. "Information Technology Security" covers three important areas of security engineering in information systems: software security, public key infrastructure and the design of new cryptographic protocols and algorithms. "Biometric Systems" comprises 11 contributions dealing with face picture analysis and recognition systems. This chapter focuses on known methods of biometric problem solution as well as the design of new models.
Enhanced Living Environments : Algorithms, Architectures, Platforms, and Systems
Ambient Assisted Living (AAL) is an area of research based on Information and Communication Technologies (ICT), medical research, and sociological research. AAL is based on the notion that technology and science can provide improvements in the quality of life for people in their homes, and that it can reduce the financial burden on the budgets of the healthcare providers. The concept of Enhanced Living Environments (ELE) refers to the AAL area that is more related with ICT. Effective ELE solutions require appropriate ICT algorithms, architectures, platforms, and systems, having in view the advance of science in this area and the development of new and innovative solutions. The aim of this book is to become a state-of-the-art reference, discussing progress made, as well as prompting future directions on theories, practices, standards, and strategies related to the ELE area.
Engineering theories of software intensive systems : Theory, algorithms, software, and applications
Software engineering has over the years been applied in many different fields, ranging from telecommunications to embedded systems in car and aircraft industry as well as in production engineering and computer networks. Foundations in software technology lie in models allowing to capture application domains, detailed requirements, but also to understand the structure and working of software systems like software architectures and programs. These models have to be expressed in techniques based on discrete mathematics, algebra and logics. However, according to the very specific needs in applications of software technology, formal methods have to serve the needs and the quality of advanced software engineering methods, especially taking into account security aspects in Information Technology. This book presents mathematical foundations of software engineering and state-of-the-art engineering methods in their theoretical substance in the step towards practical applications to examine software engineering techniques and foundations used for industrial tasks.
Engineering Statics
Focusing on practical applications knowledge, with numerous real-world examples, practice problems, and case studies throughout. It covers theory concisely and uses plain language and coverage that can be completed in a one-semester course. It also covers the related concepts required to take the Fundamentals of Engineering (FE) exam.
Engineering Mechanics ; Vol.2 : Stresses, Strains, Displacements
"This is the second of two volumes … by Hartsuijker and Welleman (both, Dolft Univ. of Technology). … The concepts and applications are well presented; applications include both basic and advanced levels. The worked out examples nicely illustrate concepts. Figures and tables are clear and help understanding of the concepts. … In summary, the book is very well written and is a welcome addition to the literature of engineering mechanics. Summing Up: Recommended. Lower-division undergraduates through professionals." (M. G. Prasad, CHOICE, Vol. 45 (7), 2008)
Engineering Evolutionary Intelligent Systems
This edited volume 'Engineering Evolutionary Intelligent Systems' deals with the theoretical and methodological aspects, as well as various evolutionary algorithm applications to many real world problems originating from science, technology, business or commerce.
Engineering a Better Future : Interplay between Engineering, Social Sciences, and Innovation
Examines how the social sciences can be integrated into the praxis of engineering and science, presenting unique perspectives on the interplay between engineering and social science. Motivated by the report by the Commission on Humanities and Social Sciences of the American Association of Arts and Sciences, which emphasizes the importance of social sciences and Humanities in technical fields, the essays and papers collected in this book were presented at the NSF-funded workshop ‘Engineering a Better Future: Interplay between Engineering, Social Sciences and Innovation’, which brought together a singular collection of people, topics and disciplines.
Energy-efficient and semi-automated truck platooning : Research and evaluation
This book presents research and evaluation results of the Austrian flagship project “Connecting Austria,” illustrating the wide range of research needs and questions that arise when semi-automated truck platooning is deployed in Austria. The work presented is introduced in the context of work in similar research areas around the world. This interdisciplinary research effort considers aspects of engineering, road-vehicle and infrastructure technologies, traffic management and optimization, traffic safety, and psychology, as well as potential economic effects.
Energy Resources in East Africa: Opportunities and Challenges
East African states have historically shared several resources including energy and common heritage of its people. This book provides information on available sources of energy in the region and how the energy suppliers can exploit them in an integrated form to produce the right blend of energy for various applications e.g., industrial, domestic and recreational uses. We provide an in-depth analysis of the advantages and disadvantages of different energy sources in-terms of environmental, industrialization, distribution costs and impacts. We hope that the book will contribute towards a sustainable exploitation of energy resources for the improvement of the people’s quality of life.
Energy Justice Across Borders
This book unites the fields of energy justice and comparative philosophy to provide an overarching global perspective and approach to applying energy ethics. We contribute to this purpose in four sections: setting the scene, practice, applying theory to practice, and theoretical approaches.
Energy and American Society – Thirteen Myths
This book takes on a central quandary in the study of energy and environmental policy: What myths continue to exist in American culture concerning energy, the environment, and society? It enrolls twenty-four of the nation’s top experts working on energy policy in industry, government laboratories, utilities, nonprofit organizations, and universities to debunk and contextualize thirteen energy myths relating to electric power, renewable energy, energy efficiency, transportation, and climate change. While the book focuses on the American experience, it will be of interest to those working in the fields of energy policy, energy and the environment, and technology assessment worldwide.
Energiya—Buran : The Soviet Space Shuttle
In Energiya-Buran: the Soviet Space Shuttle, the authors describe the long development path of the Soviet space shuttle system, consisting of the Energiya rocket and the Buran orbiter. The program eventually saw just one unmanned flight in November 1988 before the end of the Cold War and the collapse of the Soviet Union sealed its fate. After a Foreword provided by lead Buran test pilot Igor Volk, the authors look at the experience gradually accumulated in high-speed aeronautics with the development of various Soviet rocket planes and intercontinental cruise missiles between the 1930s to 1950s and the study of several small spaceplanes in the 1960s. Next the authors explain how the perceived military threat of the US Space Shuttle led to the decision in February 1976 to build a Soviet equivalent, and explore the evolution of the design until it was frozen in 1979.
End-User Development
By now, most people have become familiar with the basic functionality and interfaces of computers. However, developing new or modified applications that effectively support users' goals still requires considerable expertise in programming that cannot be expected from most people. Thus, one fundamental challenge for the coming years is to develop environments that allow users who do not have background in programming to develop or modify their own applications, with the ultimate aim of empowering people to flexibly employ advanced information and communication technologies.
Endurance time excitation functions : Intensifying dynamic loads for seismic analysis and design
Seismic assessment and earthquake-resistant design are essential applications of earthquake engineering for achieving seismic safety for buildings, bridges, infrastructure, and many other components of the built environment. The Endurance Time Method (ETM) is used for seismic analysis of simple and complex structural systems and civil engineering infrastructure as well as producing optimal and cost-effective structural and detail designs. ETM is a relatively new approach to seismic assessment and design of structures. It has developed into a versatile tool in the field, and its practical applications are expected to increase greatly in the near future.
Endourooncology : New Horizons in Endourology
Recent research and clinical work have demonstrated that the rapid urologic innovation in minimally invasive treatment is creating exciting new horizons in endourology. This sixth volume in the series Recent Advances in Endourology brings that knowledge to a wider audience, focusing on the new concept of endourooncology, which is the merging of endourology and oncology. In the surgical treatment of urologic malignancies, bipolarization - that is, radical extended resection or organ-sparing surgery - is making remarkable advances. Further developments in sophisticated reconstructive surgery using robotic systems and image-guided ablation technology will allow surgeons to formulate minimally invasive, tailor-made procedures for each patient with urologic cancer. In this book, the current status and future prospects of these new technologies are reviewed, illuminating their roles in the future of endourooncology.
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine
This is the most authoritative and wide-ranging reference yet assembled on Functional Genomics (the systematic analysis and identification of genes and their function) and Proteomics (the study of the complex structures and functions of proteins) in the rapidly expanding field of Molecular Medicine. The two-volume reference work offers a comprehensive overview of the terms, topics and issues in both molecular biology and molecular medicine, with particular emphasis placed on the molecular causes of diseases. It provides up-to-the minute information about developments in the field, including pharmacogenetics and pharmacoproteomics, gene regulation and gene therapy. The Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine is an invaluable tool for clinical scientists in academia and industry, and all who need fast and user-friendly access to key information in this dynamically developing field.
