الصفحة 83
الصفحة 83
Analysis file of drug-induced lung injury : expert opinion for analysis of big data
Describes the pathologic conditions of drug-induced lung injuries, monitoring strategies, and guides on how to interpret the evidence. It also dives into particular drugs that caused the disorder, such as EGFR inhibitors, anti-EGFR antibodies, mTOR inhibitors, proteasome inhibitors, immune checkpoint inhibitors, neoangiogenesis inhibitors, and other molecular targeted drugs. It outlines the analysis and interpretation of the post-marketing survey on surveillance of each drug for inducing pulmonary lesions presenting diffuse haziness. The data and analysis from this survey are valuable since a guideline is yet to be established due to limited clinical evidence and cases. As new drugs are developed, establishing treatment and event management is crucial.
Analysis and Simulation of Fluid Dynamics
This volume collects the contributions of a Conference held in June 2005, at the laboratoire Paul Painlev́ e (UMR CNRS 8524) in Lille, France. The meeting was intended to review hot topics and future trends in ?uid dynamics.
An Intuitive Exploration of Artificial Intelligence : Theory and Applications of Deep Learning
This book develops a conceptual understanding of Artificial Intelligence (AI), Deep Learning and Machine Learning in the truest sense of the word. It is an earnest endeavor to unravel what is happening at the algorithmic level, to grasp how applications are being built and to show the long adventurous road in the future.
An introduction to pharmacovigilance ; 2nd ed.
Designed to aid the rapid understanding of the key principles of pharmacovigilance. Packed full of examples illustrating drug safety issues it not only covers the processes involved, but the regulatory aspects and ethical and societal considerations of pharmacovigilance. Covering the basics step-by-step, this book is perfect for beginners and is essential reading for those new to drug safety departments and pharmaceutical medicine students. The second edition is thoroughly revised and updated throughout and includes a new chapter on clinical aspects of pharmacovigilance.
An Introduction to Optical Wireless Mobile Communications
Discusses existing conventional radio frequency (RF)-based wireless access technology and presents the challenges that can impact the requirements of the future wave of new wireless services in the context of artificial intelligence (AI) driven autonomous systems and machine-type communications. The relationship between visible light communications (VLC) and light fidelity (LiFi), is explored, and the major advantages of VLC and LiFi such as security and data density, and discuss existing research challenges are also introduced. Channel modeling techniques are provided for mobile multiuser scenarios, and will introduce key building blocks to achieve LiFi cellular networks achieving orders of magnitude improvements of area spectral efficiency compared to state-of-the-art. Challenges that arise from moving from a static point-to-point visible light link to a LiFi network that is capable of serving hundreds of mobile and fixed nodes are discussed. An overview of recent standardization activities and the commercialization challenges of this disruptive technology is also provided.
An introduction to medicinal chemistry
Providing an introduction to medicinal chemistry, this resource covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug
An Introduction to Formal Languages and Automata
Designed for an introductory course on formal languages, automata, compatibility, and related matters forming what is known as the theory of computation
An Introduction to Ethics in Robotics and AI
This book provides an introduction into the ethics of robots and artificial intelligence. The book was written with university students, policy makers, and professionals in mind but should be accessible for most adults. The book is meant to provide balanced and, at times, conflicting viewpoints as to the benefits and deficits of AI through the lens of ethics. As discussed in the chapters that follow, ethical questions are often not cut and dry. Nations, communities, and individuals may have unique and important perspectives on these topics that should be heard and considered. While the voices that compose this book are our own, we have attempted to represent the views of the broader AI, robotics, and ethics communities.
An introduction to bioanalysis of biopharmaceuticals
Provides a comprehensive review of the fundamental and practical aspects of bioanalytical support and the integral role it plays in the development of safe and efficacious biopharmaceutical drugs with speed and cost-effectiveness. Focuses on a broad range of conventional and emerging biopharmaceutical modalities including monoclonal antibody-based therapeutics, gene therapy, cell therapy, peptides and oligonucleotides.
An American scientist on the research frontier : Edward Morley, community, and radical ideas in nineteenth-century science
This important examination of Morley’s struggle for personal and professional legitimacy extends and transforms our understanding of science during a foundational period, and leads to a number of unique conclusions that are vital to the literature and historiography of science.
Amino acid biosynthesis : Pathways, regulation and metabolic engineering
Amino Acids Biosynthesis presents the current knowledge of fundamental as well as applied microbiology of amino acids. Topics discussed are the amino acid biosynthetic pathways, their genetic and biochemical regulation, transport of amino acids and genomics of producing microorganisms. The characterization of the control mechanisms of amino acid biosynthesis has revealed insights into principles of genetic and biochemical regulation, such as transcriptional regulators and a new class of regulatory elements, the riboswitch. The volume further deals with the metabolic engineering of microorganisms for the biotechnological production of amino acids for use as pharmaceuticals and, particularly, as food and feed additives.
Ambient intelligence : A novel paradigm
Ambient Intelligence (AmI) is an integrating technology for supporting a pervasive and transparent infrastructure for implementing smart environments. Such technology is used to enable environments for detecting events and behaviors of people and for responding in a contextually relevant fashion. AmI proposes a multi-disciplinary approach for enhancing human machine interaction. The authors start with a description of the iDorm as an example of a smart environment conforming to the AmI paradigm, and introduces computer vision as an important component of the system. Other computer vision examples describe visual monitoring for the elderly, classic and novel surveillance techniques using clusters of cameras installed in indoor and outdoor application domains, and the monitoring of public spaces. Face and speech recognition systems are also covered as well as enhanced LEGO blocks for novel educational purposes. The book closes with a provocative chapter on how a cybernetic system can be designed as the backbone of a human machine interaction.
Alzheimers Disease
Alzheimer’s disease (AD) is a neurodegenerative disease that robs the minds of our elderly population. Approximately one in every eight adults over the age of 65 and nearly half of those over 85 are afflicted with this disease. The aging population in developed societies will impose an ever increasing socioeconomic threat in the future. Current medicines for AD patients are mainly symptomatic treatments and a huge unmet medical need exists to slow the progression of this disease. A great deal of research has been dedicated to understanding the pathogenesis of AD from which comes many ideas for intervening with its progression. Some of these ideas have been fast-tracked to clinical trials due to the availability of medicines with proven clinical efficacies for other diseases (e.g. atorvastatin, simvastatin, rosiglitazone and clioquinol) while others represent novel chemical entities (e.g. glycogen synthase kinase-3 inhibitors).
Alternatives to Animal Testing : Proceedings of Asian Congress 2016
This book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs.
Alternative medicines for diabetes management : Advances in pharmacognosy and medicinal chemistry
Apart from diet and exercise, the strategic use of different classes of prescribed or non-prescribed xenobiotic compounds for the restoration of euglycemic levels in the body is well known. The ongoing rivalry between the recommended usage of allopathic medicines versus ayurvedic remedies has encouraged many researchers to focus their studies on thoroughly isolating and characterizing the extracts from different parts of plants and then evaluating their relative activities via in vitro, in vivo and in some cases clinical studies.
Alternative medicine and it's uses in the treatment of kidney disease
The aim of this article was to review some of the new and commonly and alternative medicine in the treatment of kidney used medicinal plants , pharmacological activity, and research study of disease, kidney stones medicinal plants. Renal stones are a common problem worldwide with rden substantial morbidities and economic costs. The high economic bu associated with kidney stones is linked mainly with healthcare costs. In vitro and in vivo studies on alternative treatment of kidney stones have been searched by using words such as phytotherapy of kidney stones,. lithotriptic activity of plantss, and medicinal plants used in kidney stone Medicinal plants may be useful in treatment of kidney stones.
Altering nature ; Vol.2 : Religion, Biotechnology, and Public Policy
The two volumes of Altering Nature consider the complex ways that concepts of 'nature' and 'the natural' are understood and the relevance of those understandings to discussions of biotechnology.Volume Two, Religion, Biotechnology, and Public Policy, reviews recent religious and ethical analyses of four specific areas of biotechnology: assisted reproduction, genetic therapy and enhancement, human-machine incorporation, and biodiversity. It identifies and explores the richer normative themes that inform particular debates and suggests ways that policy choices in biotechnology may be illuminated by devoting greater attention to religious perspectives.
Allocating public and private resources across generations : Riding the age waves ; Vol .2
The chapters in this volume greatly develop our understanding of the nature and measurement of transfers, their motives and mechanisms, and their macro-level dimensions, especially in the context of demographic transitions.
Allergic rhinitis
Allergic rhinitis is a very common disorder that affects people of all ages, peaking in the teenage years. It is frequently ignored, underdiagnosed, misdiagnosed, and mistreated, which not only is detrimental to health but also has societal costs. Although allergic rhinitis is not a serious illness, it is clinically relevant because it underlies many complications, is a major risk factor for poor asthma control, and affects quality of life and productivity at work or school. Management of allergic rhinitis is best when directed by guidelines. A diagnostic trial of a pharmacotherapeutic agent could be started in people with clinically identified allergic rhinitis; however, to confirm the diagnosis, specific IgE reactivity needs to be recorded.
Allergic Diseases : Diagnosis and Treatment
In this updated third edition of the critically-acclaimed volume, expert physicians assemble user-friendly, clinically-oriented guides to aid in the day-to-day management of the allergic patient. With an emphasis on common allergic diseases and the pharmacological tools to control them, Allergic Diseases: Diagnosis and Treatment, Third Edition disseminates the practical knowledge that practitioners have accumulated through practice and teaching in the field of allergy and immunology.
