الصفحة 76
الصفحة 76
Percutaneous Tumor Ablation in Medical Radiology
Thermal ablation has become an integral part of oncology, especially in the field of interventional oncology. This very comprehensive book encompasses the different technologies employed in thermal ablation, its indications and the results achieved in various clinical conditions. The first part of the book clearly explains the basics of thermal ablative techniques such as laser-induced thermotherapy, radiofrequency ablation, microwave ablation, cryotherapy, and localized tumor therapy. The latest developments in the application of minimally invasive therapies in localized neoplastic disease are demonstrated. In the main part of the book, techniques of guiding the applicators to the target structures by use of different imaging tools such as ultrasound, computed tomography and magnetic resonance imaging are discussed.
Perchlorate : Environmental Occurrence, Interactions and Treatment
Provides a detailed description of the perchlorate chemistry and recent advances in innovative remediation technologies for perchlorate contamination and their pros and cons. Additionally, it will be the first book to describe the natural occurrence of perchlorate and its unique isotopic signatures for environmental forensics and its detection in the environment, particularly the real-time analysis using surface enhanced Raman spectroscopy.
Peptide therapeutics : Fundamentals of design, development, and delivery
Explains how peptide-based drug design works, what steps are needed to develop a peptide-based therapeutic, and challenges in synthesis as well as regulatory issues. It covers the design concept of peptide therapeutics from fundamental principles using structural biology and computational approaches. A fresh graduate or a scientist who works on small molecules can use this to follow the design and development of peptide therapeutics to use as understanding the basic concepts. Each chapter is written by experts from academia as well as industry. The book provides concepts of design, synthesis, delivery, as well as regulatory affairs and manufacturing of peptides in a systematic way with examples in each case. The book can be used as a reference for a pharmaceutical or biomedical scientist or graduate student who wants to pursue their career in peptide therapeutics. Some chapters will be written as a combination of basic principles and protocol so that scientists can adopt these methods to their research work. The examples provided can be used to perform peptide formulation considerations for the designed peptides.
Peptide science : Chemical ligation, lead Generation, and therapeutic advances
Peptides are signaling molecules comprised of amino acids which play an important role in modulating certain physiological processes. They have a wide range of applications, particularly with respect to biological studies and therapeutical potentials. The explosive growth of peptide science in recent years and the variety of achievements in peptide drug discovery and related areas have made it an important area of study for new researchers and industry professionals. Overview of this burgeoning field and its major applications. Covering the chemistry, the pertinent technologies, and major existing therapies, it provides the tools required to integrate peptide research with virtually any area of research and development. Fully cognizant of the latest technological advances, it’s a must-own for anyone looking to understand a vital field of chemistry.
People, Population Change and Policies : Lessons from the Population Policy Acceptance Study ; Vol.2 : Demographic Knowledge – Gender – Ageing
This two-volume work presents social cohesion and demographic challenges that are associated with low birth rates and population ageing. It does so from the perspective of citizens and key policy actors. The work analyses peoples’ attitudes about demographic trends and expectations towards private networks and public policies. It places these in the societal context of national specificities in the fourteen countries and regards them as part of the dynamics of the European integration process. Volume 2 focuses on research findings related to general knowledge of people concerning demographic developments, gender issues, and ageing. In addition, it presents the results of a Delphi-Study on the views of key policy actors in the area of demographic developments. The volume concludes with policy implications of the findings, and a reflected overview of all results collected in the two volumes of this work.
People and Computers XIX - The Bigger Picture ; Proceedings of HCI 2005
Contains the full papers presented at HCI 2005, the 19th Annual Conference of the British HCI Group, a specialist group of the BCS. The conference has become the premiere annual conference on human-computer interaction in Europe, attracting a global audience. People and Computers XIX includes leading edge discussions outlining the latest research results and novel systems from the foremost research and development groups and laboratories throughout the world. The papers presented in this volume include contributions from leading figures in both the research and business sectors.
Pensionomics : On the Role of PAYGO in Pension Portfolios
Pensionomics puts forward a portfolio perspective on the combination of funded and unfunded pension arrangements. In a second-best type argument it is formally shown that a Pay-As-You-Go pension system can substitute the tradability of human capital: if risk-averse investors were able to directly invest into the present value of future labour income, they would allocate their pension portfolios in both human and physical capital. While this ideal form of diversification can not be implemented due to the imperfection of capital markets, one can design a typical Pay-As-You-Go system in such a way that it allows for the same intertemporal consumption allocations as the first-best solution. This replication works regardless of the demographic development.Therefore, PAYGO should play a key role in optimising the risk-return combinations for old-age savings.
Peer-to-Peer Systems III ; 3rd International Workshop, IPTPS 2004, La Jolla, CA, USA, February 26-27, 2004, Revised Selected Papers
On February 26–27, 2004, the 3rd International Workshop on Peer-to-Peer S- tems (IPTPS 2004) brought researchers and practitioners together to discuss the latest developments in peer-to-peer technologies, applications, and systems. As the third workshop in the series, IPTPS 2004 continued the success of the previous workshops in pioneering the state of the art in peer-to-peer systems and identifying key research challenges in the area. The workshop received 145 submissions in the form of ?ve-page position papers. As with previous workshops, submissions went through two rounds of reviews by an international program committee of 14 experts from industry and academia.In the ?rst round eachsubmission receivedtwo reviews.In the second round we focused our attention on submissions with either positive reviews, or with reviews that expressed substantially di?erent opinions. In addition to the technical merit, the reviewing process emphasized originality and the potential of the submission to lead to interesting discussions during the workshop.
Peer-Led Team Learning : Evaluation, Dissemination, and Institutionalization of a College Level Initiative
"Peer-Led Team Learning (PLTL) is one of the success stories resulting from the National Science Foundation's investment in educational innovation. Gafney and Varma-Nelson provide a coherent, tour-de-force look at the in-depth research that has been carried out, not only to understand the effect of PLTL on student learning, but also to understand the nature of the pedagogical method itself. This monograph is a jam-packed, one-stop destination for anyone who wants to learn what it means to understand a widespread pedagogical development in post-secondary science education."
Pediatric Orthopedics in Practice
The idea for this book originated from pediatricians who were frequently encountering patients with musculoskeletal problems and who, during a course in pediatric orthopaedics, expressed a wish for a book that would take into account the standpoint of the pediatrician, as well as those of the children and parents.This book also aims to stress the regional (rather than a systematic) subdivision of disorders. After all, a child does not come to the doctor’s office saying »I’m suffering from a growth disorder« or »I have a congenital condition«. Rather he or she will say »my back hurts« or »I have a stabbing pain in my knee«.
Pediatric Ophthalmology, Neuro-Ophthalmology, Genetics
The broad field of neuro-ophthalmology encompasses lesions of both the afferent and efferent pathways, which can result from various etiologies: tumoral, paraneoplastic, vascular, inflammatory, infectious, or hereditary, just to name a few. This volume of Essentials in Ophthalmology is dedicated to the review of new developments in neuro-ophthalmology, including those in diagnosis, physiology, investigations or therapeutic options. It is divided into six parts, designed to provide the clinician with a summary of some of the newest data regarding diseases of the optic nerve, unusual retinopathies, new methods of investigations of the retina, optic nerve, and visual brain, neuro-ophthalmic implications of some systemic disorders, oculomotility, visual rehabilitation. This up-to-date, concise, and practical book will help the clinician understand the unusual diseases of certain patients with neuro-ophthalmic disorders.
Pediatric ocular surface disease
Dedicated to pediatric ocular surface diseases. It provides an up-to-date and highly illustrated discussion of the pathophysiology, symptomatology and diagnostic and therapeutic strategies of these less commonly understood diseases, in a format that is readily absorbed by trainees and seasoned physicians alike. The aim of this book is to provide a practical and detailed understanding of ocular surface disease in the pediatric population,as many of these corneal conditions in children require unique therapeutic approaches and may have subtle presentations. Chapters will address key issues, such as dry eye disease, Steven Johnson Syndrome and neurotrophic keratitis, that can have a profound impact on children’s visual and social development.
Pediatric Nuclear Medicine / PET
Pediatric Nuclear Medicine emerged as the standard text in its field. This book has been thoroughly revised and updated to incorporate the most cutting-edge developments in pediatric nuclear medicine. Additions to the text reflect the latest advances in PET, SPECT, and oncology while still retaining the fundamentals that anchor its distinguished reputation. Pediatric Nuclear Medicine.
Pediatric Neuropathology : A Text-Atlas
Neuropathology is the foundation for understanding developmental neuroscience, pediatric neurology, and neurosurgery, but until now a comprehensive volume covering all aspects of pediatric neuropathology was not available. This atlas is thus a unique, comprehensive reference providing the fundamentals of developmental brain disorders of the nervous system that can affect fetuses, infants and young children, as well as the essentials of diagnosis in developmental brain pathology and neuroimaging. With an emphasis on the characteristic morphology and a concise summary of clinical features, pathogenesis, and genetics, the generously illustrated atlas presents more than 100 disorders, including the common diseases of the peripheral nervous system as well as genetically determined metabolic and storage diseases.
Pediatric Inflammatory Bowel Disease
Pediatric Inflammatory Bowel Diseases (IBD) are the most common and most significant chronic disorders in Pediatric Gastroenterology. The onset of Crohn disease and ulcerative colitis in the first two decades of life presents a number of diagnostic and therapeutic challenges that are unique to pediatric patients. Although the studies available for pediatric diagnosis have improved dramatically in the past three decades, the improvement in technology alone cannot account for the increased frequency of IBD recognized in early childhood. While therapy for older patients has improved dramatically with the use of immunomodulators and the development of exciting biologic strategies, rarely if ever have comprehensive studies of the pharmacokinetics, safety and efficacy of any of the IBD medications been performed in pediatric patients. A number of excellent medications are not available in liquid preparations that can be swallowed by children, and others, such as timed-release formulations, are developed for delivery to an adult gastrointestinal tract. It is unfortunate that the care we provide to children is often an extrapolation of what is known about and available for adults with IBD. Pediatric patients with IBD face a number of unique challenges.
Pediatric Dentistry
Provides dental practitioners and students with all the knowledge required in order to treat optimally the oral conditions encountered in children and adolescents and to offer appropriate guidance on subsequent oral health self-care. The use of sedation and anesthesia is then discussed, followed by detailed information on such key topics as tooth eruption and shedding, preventive and interceptive orthodontics, and control of dental caries. Restoration procedures and pulp treatment necessitated by dental caries, trauma and/or developmental anomalies are clearly described, with reference to relevant advances in dental technology and materials. Subsequent chapters focus on conditions compromising dental or general oral health in the pediatric age group, such as periodontal diseases, dental wear, dental anomalies, TMJ disorders, and soft tissue lesions.
Pediatric Bone and Soft Tissue Sarcomas
The field of pediatric bone and soft tissue sarcomas has experienced a gradual but surprising transformation. Fundamental discoveries in the molecular biology of disease, recent breakthroughs in diagnostic imaging, and revolutionary surgical techniques have created unprecedented synergies and a refreshing vision with which to approach the diagnosis and treatment of these pediatric tumors. This book highlights the paths leading to the emergence of such a new vision and presents salient concepts in epidemiology, novel tools in imaging and molecular biology, and principles of drug development as the scaffold to understanding the pathophysiology and treatment of pediatric sarcomas. The book is aimed at providing an up-to-date comprehensive reference text which articulates a multidisciplinary approach for the diagnosis and treatment of each of these often challenging diseases.
Pedagogy and ICT Use : In Schools Around the World Findings from the IEA Sites 2006 Study
What impact is the pedagogical use of ICT making in schools around the world? This book addresses such questions through an analysis of the findings from SITES 2006, an international comparative study of pedagogy and ICT use conducted under the auspices of the International Association for the Evaluation of Educational Achievement (IEA).
Peasants, farmers and scientists : A chronicle of tropical agricultural science in the twentieth cent
This book is a critical account of tropical agricultural science and agricultural development in the twentieth century, in particular in Africa. It describes successes as well as fads and failures, from the perspective of a practitioner of more than 40 years. The emphasis is on the second half of the century, but the story frequently reaches deep into the first half of the century as well.
Pearls for Leaders in Academic Medicine
"If a leader is a person who does the right thing and a manager is a person who does things right, medical school administrators today must be both." Smart, succinct, and pragmatic, Pearls for Leaders in Academic Medicine is an essential handbook for every physician who aims to succeed in the often cutthroat and complex web of medical school and hospital administration. The "pearls" format provides easily accessible and to-the-point answers to specific inquiries, making it ideal for the fast-paced, busy administrative culture. The book covers a variety of salient topics including contract negotiation, the myths of academic medicine, media relations, grant approvals, and the always difficult issue of departmental budgets.
