الصفحة 61
الصفحة 61
Dynamical Systems : Examples of Complex Behaviour
Our aim is to introduce, explain, and discuss the fundamental problems, ideas, concepts, results, and methods of the theory of dynamical systems and to show how they can be used in specific examples. Itis also important to find out when a certain dynamic behavior is stable under small perturbations, as well as to understand the various scenarios of instability. Finally, an essential aspect of a dynamic evolution is the transformation of some given initial state into some final or asymptotic state as time proceeds. The temporal evolution of a dynamical system maybe continuous or discrete, but it turns out that many of the concepts to be introduced a reuseful in either case.
Dynamic Spectrum Management : From Cognitive Radio to Blockchain and Artificial Intelligence
This book, authored by a world-leading researcher in this field, describes fundamentals of dynamic spectrum management, provides a systematic overview on the enabling technologies covering cognitive radio, blockchain, and artificial intelligence, and offers valuable guidance for designing advanced wireless communications systems.
Dynamic pricing and automated resource allocation for complex information services : Reinforcement learning and combinatorial auctions
This book develops allocation mechanisms that aim to ensure an efficient resource allocation in modern IT-services. The author presents two methods, both of which using the users’ willingness-to-pay to control the allocation process. The author generates a method to calculate dynamic resource prices.
Dynamic Fleet Management : Concepts, Systems, Algorithms & Case Studies
Dynamic Fleet Management will focus on real time management of a distribution system. The book will integrate the latest results in system design, algorithm development and system implementation, to capture the state-of-the art research and application trends.
DSP for In-Vehicle and Mobile Systems
DSP for In-Vehicle and Mobile Systems is focused on digital signal processing strategies for improving information access, command and control, and communications for in-vehicle environments. It is expected that the next generation of human-to-vehicle interfaces will incorporate speech, video/image, and wireless communication modalities to provide more comfortable and safer driving ambiance
Dry Mouth : A Clinical Guide on Causes, Effects and Treatments
This wide-ranging guide to dry mouth, or xerostomia, is intended to meet the needs of dentists by providing information on all clinically relevant aspects. After introductory discussion of salivary secretion and function, the potential causes of dry mouth, including diseases affecting saliva production, drugs and irradiation, are examined.
Drugs in palliative care
While palliative care has adopted a holistic approach to treatment / medication-driven symptom management ostensibly forms the critical aspect of care. Prescribing in palliative care can be extremely complex because the patient may often have comorbidity / or occasionally multimorbidity. The associated polypharmacy further complicates the pharmacological management of symptoms being caused by the palliative condition. This can be daunting for healthcare professionals and can negatively impact upon the effectiveness of care provided. Fully revised and updated / the third edition of Drugs in Palliative Care provides a detailed / yet concise overview of topics that are encountered in palliative care clinical practice. The book will appeal to a variety of healthcare professionals involved in the provision of palliative care and medicines information.
Drugs in Ophthalmology
This drug handbook is divided into two sections: Alphabetical Listing of Drugs Entries in this section are listed by generic name. Information for each drug is arranged in a consistent format for easy reference. Summary of Anti-infectives This section summarizes the common doses of antibiotics, antifungals, and antivirals. For each drug, the dose for each route of administration is included.
Drugs Easily Explained
Provides an overview of the most common diseases and the drugs used to treat them. The book is designed for a general audience. It provides patients with essential information about how medications work and what side effects and interactions to expect. Finally, the book gives patients advice on what they can do themselves to improve drug therapy and safety. Summaries, bullet points, tables and diagrams support the information process.
Drug-Induced Oral Complications
Provides detailed information on the prevalence and manifestations of the most important oral complications associated with different drug treatments, focusing especially on recently developed therapies. Among the diverse adverse drug reactions covered are gingival overgrowth, ulcerations, lichenoid reactions, pigmentation, and bullous reactions. The potential direct toxic effects on bone of drugs that prevent bone mass loss, such as bisphosphonates and denosumab, are fully examined, as is the occurrence of spontaneous oral bleeding in patients receiving antithrombotic therapies. Further chapters focus on drug-induced taste disorders and salivary gland disturbances, including xerostomia, swelling, and hypersalivation. The enhanced risk of oral infections when using chemotherapy and biotherapy is addressed, and the closing chapter examines drug-related perioral and facial complications. This book is a collaborative work that brings together clinicians, surgeons, and specialists in drug safety surveillance.
Drug Targets in Kinetoplastid Parasites
The book contains 12 chapters contributed by eminent scientists working in this field. The articles deal mainly with two aspects: visual identification of targets and identification of therapeutic agents.Several targets like kDNA replication machinery, purine salvage pathway, purine and pyrimidine biosynthetic pathway, histone deacetylase, DNA topoisomerases, membrane transporter proteins, glycoproteins and glycolipids are discussed in this book. Since current treatments for kinetoplastid parasitic diseases are far from ideal, there is an urgent and genuine need to develop newer compounds as antiparasitic drug candidates. Therefore evelopment of some lead compounds against these parasites as well as drug resistance are also included in this book. Moreover the vast amount of information generated after publication of the "Trytrip" genome sequence now makes possible several new approaches for target identification and discovery of therapeutic agents. This book is an outcome of the contributions of many scientists working in this important area.
Drug target selection and validation
Focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases.
Drug safety evaluation
Presents an all-inclusive practical guide for those who are responsible for developing new drugs and ensuring the safety of an ever-expanding spectrum of therapeutics. This book helps readers understand how the safety of these products are evaluated for use. Extensively revised to reflect up-to-date information, this edition includes changes to the scope of products (vaccines, small synthetic, large protein moieties, cells and tissues), harmonized global and national regulatory requirements, the therapeutic development process, and available technologies to identify and evaluate the relevance of potential patient risks
Drug discovery and development
Presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of efficacy and safety of drug candidates through preclinical testing. This book also greatly expands the focus on the clinical pharmacology, regulatory, and business aspects of bringing new drugs to the market and offers coverage of essential topics for companies involved in drug development. Historical perspectives and predicted trends are also provided.
Drawing with a tablet : Easy techniques for mastering digital drawing on location
learn step by step how to create amazing drawings while on the go. Shows sketchers how to take their digital drawing to the next level. Whether you are new to sketching or wish to try the latest technology, this useful guide shares expert tips and techniques for drawing on a tablet. With a focus on using the ProCreate tool, but with information that is relevant to other digital platforms, you will start with the basics, such as opening your file, choosing your resolution, determining your palette, and how to simplify your tools by creating a preferred set of brushes.Covers using layers and groups of layers, and shows you how to create a sketch from start to finish.
Drawing architecture and the Urban
Provides an instrumental approach to drawing, especially computer-generated drawings; it outlines how drawings should be used to convey clear and analytical information in the process of design, as well as the communication and discussion of a project. In depth examples are provided how to communicate effectively. The final section demonstrates how to transform case-studies, directly connecting an analytical approach with the design process.
Drawing Architecture : The beginner's guide to drawing and painting buildings
A comprehensive and practical guide full of advice and inspiration for anyone wishing to capture the beauty of the urban landscape. The wonderful thing about drawing buildings is that, wherever you travel around the globe, you will never be short of subjects to inspire you. From the most elaborate of Renaissance cathedrals, through to the humble garden shed, you will always be able to practise your skills and learn a few techniques in the process. This hands-on and inspirational book will encourage you to meet the exciting challenges of drawing and painting buildings using a variety of media and a wide range of techniques, including pencil, pen, graphite powder, watercolour, water-soluble pencils and Indian ink. As you work through this book, you will look at materials and their qualities then move on to explore how to put these materials to best use when drawing specific types of building. You will be led gently through levels of learning, with easy and more challenging exercises progressing your knowledge and developing your skills. As the book is divided into discrete sections, you can dip in to a particular type of building that you wish to draw, and use the information and illustration provided, while extended teaching exercises take you through the way the author approaches composing and completing a drawing.
Dose Finding in Drug Development
When you go to the pharmacy and fill a prescription, have you ever wondered if the dose of the medication is right for you? Can the dose be too low so that the drug will not work? This book answers some of these questions, and introduces the drug development process, the design and analysis of clinical trials.
Do Exclusionary Rules Ensure a Fair Trial? : A Comparative Perspective on Evidentiary Rules
This publication discusses exclusionary rules in different criminal justice systems. It is based on the findings of a research project in comparative law with a focus on the question of whether or not a fair trial can be secured through evidence exclusion. Part I explains the legal framework in which exclusionary rules function in six legal systems: Germany, Switzerland, People’s Republic of China, Taiwan, Singapore, and the United States. Part II is dedicated to selected issues identified as crucial for the assessment of exclusionary rules. These chapters highlight the delicate balance of interests required in the exclusion of potentially relevant information from a criminal trial and discusses possible approaches to alleviate the legal hurdles involved.
DNA Methylation : Basic Mechanisms
The structural and functional importance of the correct patterns of DNA methylation in all parts of a mammalian genome is not well understood. The stability, inheritability, and developmental flexibility of these patterns point to a major role that these patterns appear to play in determining structure and function of the genome.
