Implant restorations : A step-by-step guide
Provides a wealth of updated and expanded coverage on detailed procedures for restoring dental implants. Focusing on the most common treatment scenarios, it offers concise literature reviews for each chapter and easy-to-follow descriptions of the techniques, along with high-quality clinical photographs demonstrating each step.
Immunogenicity of Biopharmaceuticals
This book is intended to give a broad overview of the current state-of-the-art regarding the immune response to biopharmaceuticals. The chapters range from an overview of the immune system and factors that may trigger the immune system, via detection of antibodies and clinical implications, to various case examples and the regulatory view on immunogenicity.
Imaging of occupational and environmental disorders of the chest
This book provides an up-to-date and comprehensive approach to modern imaging of environmental and occupational diseases of the chest. The first part of the book addresses the basic knowledge required to understand imaging in this context, while the second focuses on the imaging results achieved in a variety of specific disorders. There is particular emphasis on the role of thin-section computed tomography since this technique facilitates the detection of early subclinical abnormalities.
Il senso e la narrazione = The sense and the narration
Humans are creatures of narration: infinitely they narrate and narrate themselves, intertwine dialogues, light up stories to illuminate the dark caves of the heart and the world, recover and transmute memories. We live between a firm and rough, unknowable reality, an enormous furnace of perturbations and calls and colors, and an elusive, delicate and ephemeral interiority: and between the two, between the world and us, we weave with thought and with words a fragile ponte, a bridge called sense. Swing this bridge at the unequal breath of a cosmic wind, dropping phosphoric fragments: sudden hourglasses, anonymous centaurs, sleepless geometers, distant syllogisms, vanished lineages, black basalts, crazy anchorites, silent plesiosaurs, flutes and bagpipes ... and they recompose figures, and we ask ourselves questions about those figures and tell stories. Only the vertigo of asking and narrating can give meaning to a life that some say is interwoven with pure chance. Forever detached from the flourishing matrix of the world, tormented by thought, prisoners of words, slaves of interpretation, lost in a long corridor of facing mirrors: we are at the center of a great, incomprehensible rumble.
Hydrogenosomes and Mitosomes : Mitochondria of Anaerobic Eukaryotes
"Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes" provides a summary of the current knowledge of these organelles, which occur in unicellular, often parasitic organisms, including human pathogens. The distribution of these organelles is broad, but they were detected primarily in an anoxic habitat or nutrient rich intracellular niche that permits life without the efficient energy generating system of typical mitochondria. Their common characteristic is that they lack the aerobic energy conservation system of typical mitochondria and that they are usually the site of the synthesis of iron-sulfur clusters, regarded as the only indispensable function of eukaryotic mitochondria.These mitochondria-related organelles exhibit a variety of structures and functions. This work describes properties such as protein import, structure, metabolism, adaptation, proteome and their role in drug activation and resistance. Further topics include the evolution and biogenesis of these organelles.
Human origins and environmental backgrounds
Human Origins and Environmental Backgrounds is a benchmark compendium of research that presents itself at a major paradigm shift in paleoanthropology. The editors offer a variety of theoretical approaches to puzzles on the place of the Hominidae, particularly Homo sapiens, among the Primates, including our unique bipedal positional behavior and social structure and the selective factors that might have been involved in our evolution in the broad context of Miocene and later environments. The contributors represent several generations of pioneering laboratory and field researchers from Japan, France and the United States, who have worked together over the past 40 years and who have trained future leaders in evolutionary anthropology and experimental primatology. This volume, compiled by the leading experts in the field, explores the interface between hominid origins and palaeoenvironments.
Human microbiome : Clinical implications and therapeutic interventions
The human microbiome refers to the complete microorganisms inhabiting the human body sites including skin, ear, nose, oral cavity, the genital, gastrointestinal and respiratory tracts, and body fluids such as breast milk, saliva, and urine. It is a significant and essential organ recognized for the body and has an established involvement in the host wellbeing, in terms of nutritional requirements and immunomodulation. Talks about how alteration and imbalance in the same can have clinical implications associated with a multitude of gastrointestinal, lifestyle-associated, and neurodegenerative disorders. How the proliferation of specific groups of bacteria and their metabolic activities, as a result of intestinal dysbiosis leads to the 'leaky gut' condition thereby influences brain activity via the bidirectional gut-brain axis. It also coves the importance of microbial seeding and how it can be influenced by the mode of delivery, nutrition, and medication. This book also provides various therapeutic interventions such as the establishment of stool banks and Faecal microbiota transplantation (FMT) that have recently proved promising in the treatment of ASD, Inflammatory Bowel Disease, and Ulcerative Colitis. This book provides a deeper understanding of the development of the human gut microbiome and the factors driving its dysbiosis. This book is a valuable read for health professionals, medical students, nutritionists, and scientific research communities who are eager to update themselves with recent trends in microbiome research. It will also aid gastroenterologists and nutritionists to make well-informed choices regarding therapeutic regimes.
Human Exploitation and Biodiversity Conservation
The sustainable use of biodiversity is one of the three key objectives of the 1992 "Convention on Biological Diversity". To achieve this, sound conservation practice has to be recognized as beneficial and implemented by all who access, or use it – from subsistence farmers to skiers and pharmaceutical bioprospectors. At the same time, indigenous peoples necessarily utilize enormous numbers of plants, fungi, and fish, particularly for foods and medicines. This book gathers together a wide range of contributions addressing diverse aspects of front-line human involvement in biodiversity exploitation and conservation. Its scope is broad, the organisms explored ranging from birds, invertebrates and mammals – both terrestrial and aquatic – to crops and medicinal plants. Meanwhile, the issues addressed include land use changes, the importance of gardens, hedges and green lanes, housing developments, hunting, invasive species, local community involvement, sacred groves, socioeconomic factors and trade.
Hugo and Russell's pharmaceutical microbiology
Microbiology is one of the essential pharmaceutical sciences upon which the study and practice of pharmacy is built. It has a bearing on all aspects of the manufacture of medicines and sterile products, from their design and development to their delivery as quality products. Few interventions are more central to modern medicine than the treatment of infection, where antibiosis, vaccination and hygienic practices have essential roles to play. The COVID-19 pandemic, the appearance of new pathogens and the rise of antibiotic resistance have demonstrated most completely the need for pharmaceutical practitioners, researchers and industrial scientists to be fully conversant with this field. The 9th edition of Hugo and Russell’s Pharmaceutical Microbiology has been updated to meet this need. Having long served as the sole comprehensive textbook covering this subject, it has now been adapted to a critical new period in the advancement of medical and pharmaceutical research and development. Its experienced editors have incorporated contributions from subject experts and created a text which will serve the next generation of pharmacy students, pharmaceutical industry scientists and researchers.
How humans judge machines
80 experimental scenarios help us understand how humans judge AIs as opposed to other humans in the same situation
Homocysteine
Homocysteine is a non-proteinogenic α-amino acid. It is a homologue of the amino acid cysteine, differing by an additional methylene bridge (-CH2-). It is biosynthesized from methionine by the removal of its terminal methyl group. In the body, Homocysteine (HCY) can be recycled into methionine or converted into cysteine with the aid of certain B-vitamins. A high level of Homocysteine in the blood (hyperhomocysteinemia) makes a person more prone to endothelial cell injury, which leads to inflammation in the blood vessels, which in turn may lead to atherogenesis, which can result in ischemic injury. Therefore, hyperhomocysteinemia is a possible risk factor for coronary artery disease (CAD). Coronary artery disease occurs when an atherosclerotic plaque blocks blood flow to the coronary arteries, which supply the heart with oxygenated blood.
High-Resolution If-To-Baseband ΣΔ Adc For Car Radios
High-Resolution IF-to-Baseband SigmaDelta ADC for Car Radios addresses the theory, system level design and circuit implementation of a high-resolution continuous-time IF-to-baseband quadrature SigmaDelta ADC. The target application of this ADC is in AM/FM/IBOC car radios. The ADC achieves a dynamic range of 118dB, which eliminates the need for an IF VGA or AM channel filter in car radios.
High-Grade Gliomas : Diagnosis and Treatment
This is truly an exciting time in the field of neuro-oncology, particularly in the area of hi- grade gliomas. The management of patients with high-grade gliomas has historically been one of the most challenging and disheartening fields in medicine, where failure is the rule and longevity is the exception. The jaded often state that despite purported advances in surgical and radiotherapeutic techniques and a myriad of clinical trials of medical therapies, the s- vival statistics for glioblastoma have not changed in the last three decades. The nihilism associated with these tumors is such that some practitioners still advise against treatment or even biopsy, recommending palliative care with the diagnosis based only on history and an MRI scan. If the current state-of-the-art in the diagnosis and management of high-grade gliomas was truly so bleak, there would be no reason to compile and publish a monograph on the subject. The fact is that we have recently entered an era where real progress is being made in our understanding and treatment of high-grade gliomas that is directly benefiting some patients. We are slowly but surely chipping away at this problem. One approach has exploited correlations between particular molecular markers and therapeutic response.
High performance computing for computational science - VECPAR 2008 ; 8th International Conference, Toulouse, France, June 24-27, 2008. Revised Selected Papers
This book constitutes the thoroughly refereed post-conference proceedings of the 8th International Conference on High Performance Computing for Computational Science, VECPAR 2008, held in Toulouse, France, in June 2008.The 51 revised full papers presented together with the abstract of a surveying and look-ahead talk were carefully reviewed and selected from 73 submissions. The papers are organized in topical sections on parallel and distributed computing, cluster and grid computing, problem solving environment and data centric, numerical methods, linear algebra, computing in geosciences and biosciences, imaging and graphics.
Heterogeneous Enantioselective Hydrogenation : Theory and Practice
The book looks at the first relatively ineffective catalysts right through to modern highly effective enantioselective catalytic systems, comparable in their efficiency to chiral metal complexes and enzymatic systems. The book begins with a summary of the first work on heterogeneous metal catalysts, which showed only the principal possibilities of enantioselective reactions. The book then elaborates on metal catalysts which have enantioselectivities close to 100%. Finally, the book describes the practical utilization of chiral catalytic systems in processes of hydrogenation. The a - and b -hydroxy carboxylic acid esters produced are precursors for manufacturing many synthones used for medicines as well as for monomers used for biodegradable polyesters, both of which have important practical applications. The book summarizes more than 800 scientific papers in the field of enantioselective catalytic hydrogenation reactions, mainly those using heterogeneous metal catalysts. It provides detailed explanations of special techniques for the preparation of effective dissymmetric catalysts which provide highly efficient catalytic systems.
Heterogeneity in statistical genetics : How to assess, address, and account for mixtures in association studies
Heterogeneity, or mixtures, are ubiquitous in genetics. Even for data as simple as mono-genic diseases, populations are a mixture of affected and unaffected individuals. Still, most statistical genetic association analyses, designed to map genes for diseases and other genetic traits, ignore this phenomenon.In this book, we document methods that incorporate heterogeneity into the design and analysis of genetic and genomic association data. Among the key qualities of our developed statistics is that they include mixture parameters as part of the statistic, a unique component for tests of association. A critical feature of this work is the inclusion of at least one heterogeneity parameter when performing statistical power and sample size calculations for tests of genetic association.
Healthcare solutions using machine learning and informatics
Covers novel and innovative solutions for the healthcare that apply machine learning and biomedical informatics technology. The healthcare sector is one of the most critical in society. This book presents a series of artificial intelligence, machine learning, intelligent IoT-based solutions for medical image analysis, medical big data processing, disease predictions. Machine learning and artificial intelligence use cases in healthcare presented in the book give researchers, practitioners, and students a wide range of practical examples of cross-domain convergence. The wide variety of topics covered include: Artificial Intelligence in healthcare Machine learning solutions for such disease as diabetes, arthritis, cardiovascular disease, and COVID-19 Big data analytics solutions for healthcare data processing Reliable biomedical applications using AI models Intelligent IoT in healthcare. The book explains fundamental concepts as well as the advanced use cases illustrating how to apply emerging technologies such as machine learning, AI models, data informatics into practice to tackle challenges in the field of healthcare with real-world scenarios. Chapters contributed by noted academicians and professionals examine various solutions, frameworks, applications, case studies, and best practices in the healthcare domain
Health information systems : Technological and management perspectives
Details a variety of scenarios in the context of both health and heath care, including where prevention and wellness are related, such as the treatment of both acute and chronic diseases. Stakeholder requirements are also described to provide perspectives for describing the architectures and management techniques associated with health information systems, enabling the reader to develop a detailed holistic overview of the subject. Health Information Systems: Technological and Management Perspectives features a detailed overview of how information systems in health care can be managed and is a vital resource for medical informatics students seeking an up-to-date text on the topic.
Headache and Chronic Pain Syndromes
Headache and Chronic Pain Syndromes provides a case-based approach to state-of-the-art evaluation and treatment of patients with common chronically painful conditions. Offering strategies for rapidly evaluating and treating pain complaints by body region, this innovative title also provides patient educational handouts that explain the diagnosis and treatment in easy-to-understand language for each condition. Tools for implementing both medication and non-medication therapies, such as exercises and relaxation techniques, are also included. Each chapter opens with typical presentations of three to five common patient scenarios, including pediatric, adult, and geriatric patients. A targeted approach for patient assessment is provided and applied to each scenario, showing how to rapidly identify important clues to distinguish among common diagnoses, including both benign and malignant causes of pain. Standard treatment regimens are then provided for each patient, along with patient-friendly educational flyers for each common pain condition. Figures and drawings help provide ready identification of these common chronic pain syndromes.
Haptics : Perception, Devices and Scenarios ; 6th International Conference, EuroHaptics 2008 Madrid, Spain, June 10-13, 2008 Proceedings
This book constitutes the refereed proceedings of the 6th International Conference on Human Haptic Sensing and Touch Enabled Computer Applications, EuroHaptics 2008, held in Madrid, Spain, in June 2008.The 119 revised full papers presented were carefully reviewed and selected from 150 submissions. The papers are organized in topical sections on control and technology, haptic perception and psychophysics, haptic devices, haptics rendering and display, multimodal interaction and telepresence, as well as haptic applications.



















