الصفحة 6
الصفحة 6
Microfluidics diagnostics : Methods and protocols
Explores a wide range of microfluidic-based approaches that exploit the unique features of microfluidic devices, which hold significant potential in the field of diagnosis. Beginning with a section on microchips for sample preparation, including cell-free DNA, exosomes, and cells, the book continues by covering protein marker analysis and detection, single-cell analysis, analysis of bacteria and viruses, as well as human cell-based culture and analysis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Microfinance, EU structural funds and capacity building for managing authorities : A comparative analysis of European convergence regions
Presents a study of capacity building and structural funds in public managing authorities for the microcredit sector. It presents two surveys to highlight the strengths and weaknesses of the managing authorities' capacity building. The first survey investigates the authorities' need for and interests in capacity building activities, assessing the areas in which capacity building support is needed, and explores the different types of support offered. The second survey analyses the results of the microcredit and microfinance programming activity, investigating its target groups and other operational features. It examines the key monitoring and reporting issues involved in this activity, before analysing the regulatory framework of the microcredit and microfinance sector.
Microeconomics for Managers ; 2nd ed.
Shows future managers how economics can provide practical answers to critical business problems. Focuses on case studies and real companies, such as Amazon, Microsoft, General Motors, United Airlines, and Xerox. Covers essential topics for future managers—including price discrimination, Porter’s five forces, risk sharing and spreading, signaling and screening, credibility and reputation, and economics and organizational behavior / Features an online supplement (available at micro4managers.stanford.edu) for students that provides solutions to the problems in the book, longer caselike exercises, review problems, a calculus review, and more
Micro-Assembly Technologies and Applications ; IFIP TC5 WG5.5 Fourth International Precision Assembly Seminar (IPAS’2008) Chamonix, France February 10–13, 2008
The IFIP series publishes state-of-the-art results in the sciences and technologies of information and communication. The scope of the series includes: foundations of computer science; software theory and practice; education; computer applications in technology; communication systems; systems modeling and optimization; information systems; computers and society; computer systems technology; security and protection in information processing systems; artificial intelligence; and human-computer interaction. Proceedings and post-proceedings of referred international conferences in computer science and interdisciplinary fields are featured. These results often precede journal publication and represent the most current research.
Microarray technology and cancer gene profiling
Cancer is a heterogeneous disease in most respects, including its cellularity, different genetic alterations and diverse clinical behaviors. In the present book, written by leading experts in each field, the technical features characterizing this powerful laboratory tool are discussed, and the applications so far described in the field of oncology are reviewed.
Methods of Legal Reasoning
The book attempts to describe and criticize four methods used in legal practice, legal dogmatics and legal theory: logic, analysis, argumentation and hermeneutics. Apart from a presentation of basic ideas connected with the above mentioned methods, the essays contained in this book seek to answer questions concerning the assumptions standing behind these methods, the limits of using them and their usefulness in the practice and theory of law. A specific feature of the book is that in one study four different, sometimes competing concepts of legal method are discussed. The panorama, sketched like this, allows one to reflect deeply on the questions concerning the methodological conditioning of legal science and the existence of a unique, specific legal method. The authors argue that there exists no such method.
Metalliferous Sediments of the World Ocean : Fundamental Theory of Deep-Sea Hydrothermal Sedimentation
Dramatic advances in understanding global tectonics have been made in the last half century and the information and specific data acquired on the floor of the World Ocean by the scientific community probably has exc- ded that available in all previous time. With the benefit of new technology and advanced concepts in the earth sciences extensive exploration of the deep seabed became possible, and has been carried out in many parts of the world. Many features have been recognized and data recorded that are vital for understanding the fundamental processes that shape the earth=s surface and control the habitable environment. The data collected to date on the o- an floor and its physical environment greatly exceeds our understanding and appreciation of their fundamental importance in the earth sciences, and our ability to apply this knowledge effectively in improving our way of life.
Metakaolin and Fly Ash as Mineral Admixtures for Concrete
Deals with modern theoretical concepts related to the impact of fly ash and metakaolin admixtures on structure formation processes of concrete. Results of the effect of fly ash, metakaolin and their composition on properties of self-compacting and self-leveling concrete are presented. Based on mathematical models, obtained using mathematical experiments planning methodology, the impact of the main factors and their combination on workability, strength and other properties that determine efficiency and durability of concrete are analyzed. Using calculated dependencies, a methodology for designing optimal compositions of concrete containing active mineral admixtures and superplasticizers is proposed. Features of industrial production of concrete for the proposed compositions are discussed. The book is intended for specialists working in the production of concrete and reinforced concrete products and elements. It can also be used by construction engineers to design compositions of cost-effective self-compacting and self-leveling concrete as well as to determine the rational direction of using technogenic raw materials like ash and metakaolin.
Metaheuristics for Scheduling in Industrial and Manufacturing Applications
This book deals with the application of various novel metaheuristics in scheduling. Addressing the various issues of scheduling in industrial and manufacturing applications is the novelty of this edited volume. Important features include the detailed overview of the various novel metaheuristic scheduling approaches, excellent coverage of timely, advanced scheduling topics, state-of-the-art theoretical research and application developments and chapters authored by pioneers in the field.
Meeting Basic Learning Needs in the Informal Sector : Integrating Education and Training for Decent Work, Empowerment and Citizenship
This anthology brings together basic facts and features about basic learning needs and skills of people working and living in the informal economy and presents case studies from different countries examining educational and training strategies for meeting these learning needs. It portrays the grave problems facing educational and training systems vis-á-vis informal sector workers, even as they look at holistic solutions that take into account principles of lifelong learning and innovations in informal, non-formal and formal adult learning, and show a growing awareness that education is a human right of fundamental significance to promoting decent work and humane living conditions.
Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes
Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes features important insights into the applications of fullerenes and carbon nanotubes. It discusses the fullerene and nanotubes derivatives which are effective against viruses, cells, and bacteria and those which are able to interact and inhibit certain enzymes. Also covered in this book are the formation of complex structures between biologically active molecules and carbon materials. Furthermore, the application of fullerenes in certain medical therapies is explored, including the very recent discovery of new bio-compatible media which could be used as carriers in the delivery of fullerenes in vivo. An additional topic of this text is the formation of hybrids between nanotubes and biological molecules and their use as chemical sensors.
Medical laboratory technology procedure : manual for routine diagnostic tests ; Vol.3
Salient features Predominantly tailored to the requirements of laboratories with limited facilities in developing countries, this manual: Introduces methods and procedures for producing reliable laboratory findings Describes all tests in a step-by-step manner with guidelines to avoid errors and hazards Explains care and use of laboratory equipment and preparation of reagents Details Zika and Chikungunya virus infections Highlights the clinical significance of laboratory findings Provides illustrations for easy comprehension The fourth edition features a number of important additions containing the latest topics relevant to the subject
Medical Image Computing and Computer-Assisted Intervention – MICCAI 2006 ; Vol. 4191; 9th International Conference, Copenhagen, Denmark, October 1-6, 2006, Proceedings, Part II
T MICCAI papers are of high standard and have a long lifetime. In this v- ume as well as in the latest journal issues of Medical Image Analysis and IEEE Transactions on Medical Imaging papers cite previous MICCAIs including the ?rst MICCAI conference in Cambridge, Massachusetts, 1998. It is obvious that the community requires the MICCAI papers as archive material. Therefore the proceedingsofMICCAIarefrom2005andhenceforthbeing indexedbyMedline. Acarefulreviewandselectionprocesswasexecutedinordertosecurethebest possible program for the MICCAI 2006 conference. We received 578 scienti?c papers from which 39 papers were selected for the oral program and 193 papers for the poster program.
Medical Image Computing and Computer-Assisted Intervention – MICCAI 2006 ; Vol. 4190 ; 9th International Conference, Copenhagen, Denmark, October 1-6, 2006, Proceedings, Part I
MICCAI papers are of high standard and have a long lifetime. In this v- ume as well as in the latest journal issues of Medical Image Analysis and IEEE Transactions on Medical Imaging papers cite previous MICCAIs including the ?rst MICCAI conference in Cambridge, Massachusetts, 1998. It is obvious that the community requires the MICCAI papers as archive material. Therefore the proceedingsofMICCAIarefrom2005andhenceforthbeing indexedbyMedline. Acarefulreviewandselectionprocesswasexecutedinordertosecurethebest possible program for the MICCAI 2006 conference. We received 578 scienti?c papers from which 39 papers were selected for the oral program and 193 papers for the poster program.
Medical Image Computing and Computer-Assisted Intervention – MICCAI 2005 ; 8th International Conference, Palm Springs, CA, USA, October 26-29, 2005, Proceedings, Part I
This paper presents a method for classification of medical images, using machine learning and deformation-based morphometry. A morphological representation of the anatomy of interest is first obtained using highdimensional template warping, from which regions that display strong correlations between morphological measurements and the classification (clinical) variable are extracted using a watershed segmentation, taking into account the regional smoothness of the correlation map which is estimated by a crossvalidation strategy in order to achieve robustness to outliers. A Support Vector Machine-Recursive Feature Elimination (SVM-RFE) technique is then used to rank computed features from the extracted regions, according to their effect on the leave-one-out error bound. Finally, SVM classification is applied using the best set of features, and it is tested using leave-one-out. The results from a group of 61 brain images of female normal controls and schizophrenia patients demonstrate not only high classification accuracy (91.8%) and steep ROC curves, but also exceptional stability with respect to the number of selected features and the SVM kernel size
Medical Biometrics ; 1st International Conference, ICMB 2008, Hong Kong, China, January 4-5, 2008, Proceedings
Medical biometrics primarily refers to the usage of beh- ioral and physiological characteristics of humans for medical diagnosis and body care. Thus the goal of medical biometrics is to explore solutions to the open problems in medicine using biometric measurements, technologies and systems.
Media Theory : Interdisciplinary Applied Mathematics
The focus of this book is a mathematical structure modeling a physical or biological system that can be in any of a number of `states.' Each state is characterized by a set of binary features, and differs from some other neighbor state or states by just one of those feature. A simple example of a `state’ is a partial solution of a jigsaw puzzle, which can be transformed into another partial solution or into the final solution just by adding or removing a single adjoining piece. The evolution of such a system over time is considered. Such a structure is analyzed from algebraic and probabilistic (stochastic) standpoints.
Mechanisms of Insulin Action
More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. In addition, between 17 and 40 million people have insulin resistance, impaired glucose tolerance, or the cluster of abnormalities referred to variably as the metabolic syndrome, the dysmetabolic syndrome, syndrome X, or the insulin resistance syndrome. In all of these disorders, a central component of the pathophysiology is insulin resistance, i.e., reduced responsiveness to insulin in tissues such as muscle, fat and liver. Insulin resistance is also closely linked to other common health problems, including obesity, polycystic ovarian disease, hyperlipidemia, hypertension, and atherosclerosis. In this book, we will attempt to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. We explore insulin action at the most basic levels, through complex systems. The book will be appealing to basic and clinical scientists.
Mechanics and Physics of Fracture : Multiscale Modeling of the Failure Behavior of Solids
Provides a comprehensive understanding of the macroscopic failure behavior of solids from the description of the microscopic failure processes and their coupling with the microstructure. Several fundamental questions were addressed: the relation between the microstructural features of materials and their fracture properties and crack trajectories; the role of damage mechanisms and non-linear deformations near the crack tip on the failure behavior of solids; and finally the role of dynamic inertial effects during fast fracture was more briefly evoked.
Meaning-Making for Living : The Emergence of the Presentational Self in Children’s Everyday Dialogues
This Brief analyzes the dynamics in which children’s selves emerge through their everyday activities of meaning construction, both in their relationships with family and within school education. It begins with a discussion of new psychological inquiries into children's selves and builds upon the innovative theoretical notion of the Presentational Self, developed by the author over the last decade. The book illustrates how the observation of children’s meaning construction in their everyday lives becomes a starting point for theoretical and empirical inquiries into child development and gives a framework that promotes new inquiries in this area. The book describes the Presentational Self Theory as a sense of how the notion of the Self is being worked upon in everyday life encounters. Chapters feature in-depth analyses of exchanges between adults and children in the Japanese cultural context.
