الصفحة 5
الصفحة 5
Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity
This comprehensive volume, written by experts in the integrative fields of neuroscience, endocrinology and immunology, provides insight into the mechanisms by which neural and neuroendocrine factors influence susceptibility to infection and autoimmunity. The book focuses on multiple sclerosis as the prototypic autoimmune disease and discusses infectious diseases including anthrax, influenza virus, herpes virus and human immunodeficiency virus. The effects of stress on experimental models of multiple sclerosis and also clinical observations of stress in multiple sclerosis patients are discussed. Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity is an ideal book for researches and professionals in the fields of immunology, neuroscience, infectious disease, psychology, microbiology, virology, public health and pharmaceutical sciences.
NETWORKING 2008 Ad Hoc and Sensor Networks, Wireless Networks, Next Generation Internet ; 7th International IFIP-TC6 Networking Conference Singapore, May 5-9, 2008 Proceedings
The 82 revised full papers were carefully reviewed and selected from numerous submissions for inclusion in the book. The papers are organized in topical sections on ad hoc and sensor networks: design and optimization, MAC protocol, overlay networking, and routing; next generation internet: authentication, modeling and performance evaluation, multicast, network measurement and testbed, optical networks, peer-to-peer and overlay networking, peer-to-peer services, QoS, routing, security, traffic engineering, and transport protocols; wireless networks: MAC performance, mesh networks, and mixed networks.
Network Classification For Traffic Management : Anomaly detection, feature selection, clustering and classification
Investigates network traffic classification solutions by proposing transport-layer methods to achieve better run and operated enterprise-scale networks. With the massive increase of data and traffic on the Internet within the 5G, IoT and smart cities frameworks, current network classification and analysis techniques are falling short. Novel approaches using machine learning algorithms are needed to cope with and manage real-world network traffic, including supervised, semi-supervised, and unsupervised classification techniques. Accurate and effective classification of network traffic will lead to better quality of service and more secure and manageable networks. Investigates network traffic classification solutions by proposing transport-layer methods to achieve better run and operated enterprise-scale networks. The authors explore novel methods for enhancing network statistics at the transport layer, helping to identify optimal feature selection through a global optimization approach and providing automatic labelling for raw traffic through a SemTra framework to maintain provable privacy on information disclosure properties.
Neglected tropical diseases and phytochemicals in drug discovery
Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections.
Nb3Sn Accelerator Magnets : Designs, Technologies and Performance
This book is written by world-recognized experts in the fields of applied superconductivity and superconducting accelerator magnet technologies. It provides a contemporary review and assessment of the experience in research and development of high-field accelerator dipole magnets based on Nb3Sn superconductor over the past five decades. The reader attains clear insight into the development and the main properties of Nb3Sn composite superconducting wires and Rutherford cables, and details of accelerator dipole designs, technologies and performance. Special attention is given to innovative features of the developed Nb3Sn magnets. The book concludes with a discussion of accelerator magnet needs for future circular colliders.
Natural Products Targeting Clinically Relevant Enzymes
Covers the full spectrum of clinically relevant enzymes that are known to be targeted by natural products. Key enzymes include acetylcholine esterase, angiotensin-I-converting enzyme, cyclooxygenase, dihydrofolate reductase, phospholipase A2, respiratory complexes, and many more. By connecting the diversity of medicinal natural product sources with their potential clinical applications, this volume serves as a companion for the medicinal chemist looking for innovative small molecule compounds as well as for pharmacologist interested in the clinical effects and mode of action of herbal and traditional medicines.
Natural products and human diseases : Pharmacology, molecular targets, and therapeutic benefits
Provides insight into the clinical and translational application of natural products in human diseases Details the impact of natural products on a molecular basis Describes the identification of biomarkers, therapeutic effects of phytochemicals, and and new targets
Natural Products : Drug Discovery and Therapeutic Medicine
Although the natural product drug discovery programs of the large drug companies are now equaled by programs for the high throughput screening of synthetic compounds generated through combinatorial chemistry, natural compounds still hold great promise to overcome such problems as antibiotic resistance, the emergence of new diseases, the failure to conquer old diseases, and the toxicity of some contemporary medical products. In Natural Products: Drug Discovery and Therapeutic Medicine, a panel of recognized experts and leaders in the field discuss the past successes of natural products as medicines and review future possibilities arising from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discovery, to accessing microbial diversity, to investigating specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to exploiting specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
Natural product experiments in drug discovery
Explores a wide range of evidence-based complementary medicine and various bio-analytical techniques used to define botanical products. Collecting recent work and current developments in the field of contemporary phytomedicine as well as their future possibilities in human health care, the book includes unique contributions in the form of chapters on phytomedicine and screening biological activities explained with diverse hyphenated techniques, as well as issues related to herbal medications, such as efficacy, adulteration, safety, toxicity, regulations, and drug delivery. Written for the Springer Protocols Handbooks series, chapters feature advice from experts on how to best conduct future experiments. Extensive and practical, Natural Product Experiments in Drug Discovery serves as an ideal reference for students, professors, and researchers in universities, R&D institutes, pharmaceutical and herbal enterprises, and health organizations.
Natural Polysaccharides in Drug Delivery and Biomedical Applications
Provides a fundamental overview of natural polysaccharides, their sources, extraction methodologies, and characterizations. It covers specific natural polysaccharides and their effective application in drug delivery and biomedical use. Additionally, chapters in the book discuss key topics including the sources and extraction methodologies of natural polysaccharides, their role in tissue engineering applications, polysaccharide-based nanoparticles in biomedical applications, and their role in the delivery of anticancer drugs. Written by industry leaders and edited by experts, this book emphasizes recent advances made in the field.Natural Polysaccharides in Drug Delivery and Biomedical Applications provides academics, researchers, and pharmaceutical health care professionals with a comprehensive book on polysaccharides in pharmaceutical delivery process.
Natural poisons and venoms: Plant toxins : Polyketides, phenylpropanoids and further compounds
Biogenic toxins are fascinating natural products characterized by an enormous diversity of chemical structures and pharmacological activities. They not only pose hazards to humans and animals, but they are important components in the interplay of substances and living beings in nature and, moreover, important sources for new drugs.
Natural poisons and venoms : Animal toxins
Biogenic toxins are fascinating natural products characterized by an enormous diversity of chemical structures and pharmacological activities. They not only pose hazards to humans and animals, but they are important components in the interplay of substances and living beings in nature and, moreover, important sources for new drugs.
Natural poisons and venom : Plant toxins : Terpenes and steroids
Biogenic toxins are fascinating natural products characterized by an enormous diversity of chemical structures and pharmacological activities. They not only pose hazards to humans and animals, but they are important components in the interplay of substances and living beings in nature and, moreover, important sources for new drugs.
Natural occurrence and biological activities of quinoline derivatives
Provides a comprehensive overview of quinoline derivatives, focusing on their chemical structure, biological activities, and therapeutic benefits. It delves into the natural sources of these derivatives, covering their isolation, characterization, and potential therapeutic applications, particularly in areas such as anti-cancer, anti-inflammatory, antimicrobial, and antimalarial activity. With its emphasis on providing valuable reference material, this book is an indispensable resource for researchers, educators, and professionals in the fields of chemistry, biology, pharmacology, and drug discovery.
Natural Language Processing and Information Systems ; Vol. 3513 ; 10th International Conference on Applications of Natural Language to Information Systems, NLDB 2005, Alicante, Spain, June 15-17, Proceedings
The development and convergence of computing, telecommunications and information systems has already led to a revolution in the way that we work, communicate with each other, buy goods and use services, and even in the way that we entertain and educate ourselves.The revolution continues, and one of its results is that large volumes of information will increasingly be held in a form which is more natural for users than the data presentation formats typical of computer systems of the past. Natural language processing (NLP) is crucial in solving these problems, and language technologies will make an indispensable contribution to the success of information systems. We hope that NLDB 2005 was a modest contribution to this goal. NLDB 2005 contributed to advancing the goals and the high international standing of these conferences, largely due to its Program Committee, composed of renowned researchers in the field of natural language processing and inf- mation system engineering. Papers were reviewed by three reviewers from the Program Committee. This clearly contributed to the significant number of - pers submitted (95). Twenty-nine were accepted as regular papers, while 18 were accepted as short papers.
Natural language processing and information systems ; 12th International Conference on Applications of Natural Language to Information Systems, NLDB 2007, Paris, France, June 27-29, 2007, Proceedings
NLP techniques may substantially enhance most phases of the information system lifecycle, starting with requirement analysis, specification and validation, and going up to conflict resolution, result processing and presentation.
Natural Language Processing and Chinese Computing ; 9th CCF International Conference, NLPCC 2020, Zhengzhou, China, October 14–18, 2020, Proceedings, Part II
This two-volume set of LNAI 12340 and LNAI 12341 constitutes the refereed proceedings of the 9th CCF Conference on Natural Language Processing and Chinese Computing, NLPCC 2020, held in Zhengzhou, China, in October 2020. The 70 full papers, 30 poster papers and 14 workshop papers presented were carefully reviewed and selected from 320 submissions. They are organized in the following areas: Conversational Bot/QA; Fundamentals of NLP; Knowledge Base, Graphs and Semantic Web; Machine Learning for NLP; Machine Translation and Multilinguality; NLP Applications; Social Media and Network; Text Mining; and Trending Topics.
Natural language processing and chinese computing ; 9th CCF International conference, NLPCC 2020, Zhengzhou, China, October 14–18, 2020, Proceedings, Part I
This two-volume set of LNAI 12340 and LNAI 12341 constitutes the refereed proceedings of the 9th CCF Conference on Natural Language Processing and Chinese Computing, NLPCC 2020, held in Zhengzhou, China, in October 2020. The 70 full papers, 30 poster papers and 14 workshop papers presented were carefully reviewed and selected from 320 submissions. They are organized in the following areas: Conversational Bot/QA; Fundamentals of NLP; Knowledge Base, Graphs and Semantic Web; Machine Learning for NLP; Machine Translation and Multilinguality; NLP Applications; Social Media and Network; Text Mining; and Trending Topics.
Natural Language Processing – IJCNLP 2005 ; 2nd International Joint Conference, Jeju Island, Korea, October 11-13, 2005, Proceedings
The Theme of IJCNLP 2005: “NLP with Kimchee”, a Conference with a Unique Flavor Welcometo IJCNLP 2005,thesecondannualconferenceof theAsian Federation ofNaturalLanguageProcessing(AFNLP). Followingthesuccessofthe?rstc- ference held in the beautiful cityof Sanya,Hainan Island,China, in March2004, IJCNLP 2005 is held in yet another attractive Asian resort, namely Jeju Island in Korea, on October 11–13, 2005
Natural Language Processing – IJCNLP 2004 ; 1st International Joint Conference, Hainan Island, China, March 22-24, 2004, Revised Selected Papers
This book constitutes the thoroughly refereed post-proceedings of the First International Joint Conference on Natural Language Processing, IJCNLP 2004, held in Hainan Island, China in March 2004. The 84 revised full papers presented in this volume were carefully selected during two rounds of reviewing and improvement from 211 papers submitted. The papers are organized in topical sections on dialogue and discourse; FSA and parsing algorithms; information extractions and question answering; information retrieval; lexical semantics, ontologies, and linguistic resources; machine translation and multilinguality; NLP software and applications, semantic disambiguities; statistical models and machine learning; taggers, chunkers, and shallow parsers; text and sentence generation; text mining; theories and formalisms for morphology, syntax, and semantics; word segmentation; NLP in mobile information retrieval and user interfaces; and text mining in bioinformatics.
