الصفحة 5
الصفحة 5
Introduction to organic and medicinal chemistry
Designed to be an undergraduate reference textbook for students of chemistry who aim to select degree modules geared towards medicinal chemistry. The first two chapters offer an overview of basic organic chemistry, followed by organic synthesis in Chapter 3, with an emphasis on the importance of synthetic procedures in relation to the chemistry of drug design. In Chapter 4, the book covers foundational aspects of biochemistry and biomedical science to provide a basis for students understanding where and how drugs work on selected targets. Later, the book explains how medicines have been created for selected topics in medicinal chemistry – namely against pathogens, cancer and neurological targets.
Introduction to Empirical Processes and Semiparametric Inference
This book provides a self-contained, linear, and unified introduction to empirical processes and semiparametric inference. These powerful research techniques are surprisingly useful for developing methods of statistical inference for complex models and in understanding the properties of such methods. The targeted audience includes statisticians, biostatisticians, and other researchers with a background in mathematical statistics who have an interest in learning about and doing research in empirical processes and semiparametric inference but who would like to have a friendly and gradual introduction to the area. The book can be used either as a research reference or as a textbook. The level of the book is suitable for a second year graduate course in statistics or biostatistics, provided the students have had a year of graduate level mathematical statistics and a semester of probability.
Introduction to Biosemiotics : The New Biological Synthesis
This book is addressed to students, researchers and academics who have barely heard of the emerging young science of Biosemiotics, and who want to know more about it. Written by many of the field’s major contributors, it provides a highly qualified introduction to Biosemiotics and illustrates the most recent views in its background and development.
Introduction to biologic and biosimilar product development and analysis
Gives a concise introduction to development and analysis of pharmaceutical biologics for those in the pharmaceutical industry who are switching focus from small molecules to biologics processing, analysis, and delivery. In order to maintain a limited focus, Introduction to Biologic and Biosimilar Product Development and Analysis, will deal only with peptides, proteins and monoclonal antibodies.
Introduction to basics of pharmacology and toxicology ; Vol.3 : Experimental pharmacology : Research methodology and biostatistics
Elaborates on the general principles of experimental pharmacology. Describes about the screening methods for the evaluation of different categories of drugs. Summarizes the various aspects of research methodology and biostatistics.
Interventions for Persisting Ductus Arteriosus in the Preterm Infant
Over the past few years a remarkably rapid evolution in the professional level of neonatology and in the survival of immature infants has been witnessed. Persisting ductus arteriosus is common in this population and is associated with impaired longterm outcome. Many uncertainties exist concerning indication, approach, best time, and side effects of necessary measurements and interventions to avoid later neurodevelopmental handicaps of the survivors. Experts in neonatology and pediatric cardiology give their opinion in this book. We are sure it will help to define the level of evidence and to develop standards of intervention for persisting ductus arteriosus in Europe. Adequate dealing with the ductus will become a challenge for every perinatal center.
Internet and Network Economics ; Vol. 4286 ; 2nd International Workshop, WINE 2006, Patras, Greece, December 15-17, 2006, Proceedings
Constitutes the refereed proceedings of the Second International Workshop on Internet and Network Economics, WINE 2006, held in Patras, Greece in December 2006. The 32 revised full papers presented together with 3 invited talks were carefully reviewed and selected from 79 submissions. The papers contain foundational and mathematical work from theories, methodologies, and applications in computer science, economics, mathematics, and management sciences for solving problems arisen in internet technologies, grid computing, network communication protocols, as well as social economic issues in virtual communities enabled through the World Wide Web.
International Organizations in Global Social Governance
This book enhances and systematizes our understanding of IOs in global social governance. It provides studies on a variety of social policy fields in which different, but also the same, International Organizations (IOs) operate.
Interface oral health science 2016 : Innovative research on biosis-abiosis intelligent interface
This volume broadens understanding of dentistry and promotes interdisciplinary research across a wide range of related fields, based on the symposium entitled "Innovative Research for Biosis–Abiosis Intelligent Interface 2016". It aims to create highly functional and autonomic intelligent interface by combining highly functional interface science with the technology of an evaluation and a control at the interface, with the various topics of biomaterials, innovation for oral science and application, regenerative oral science, and medical engineering. Since 2002, the Tohoku University Graduate School of Dentistry has hosted “Interface Oral Health Science” several times as the main theme of dental research in the twenty-first century, and this is the sixth proceedings of the symposiums following the ones in 2005, 2007, 2009, 2011, and 2014.
Interface oral health science 2014 : Innovative research on biosis-abiosis intelligent interface
The Tohoku University Graduate School of Dentistry first introduced the concept of “Interface Oral Health Science”, designed to establish and maintain healthy oral cavities, which are home to a number of mixed systems. Included in those systems are: (1) host tissues such as teeth, mucosa, muscle and bone, (2) parasites and microorganisms cohabiting the surfaces of the oral cavity, and (3) biomaterials that are used for the rehabilitation of oral functions. In addition, (4) these systems are subject to severe and complex mechanical forces. Therefore, it is critical to promote dental studies that integrate a wide range of interdisciplinary research as medicine, agriculture, material science, engineering, and pharmacology.
Interest Rate Models : an Infinite Dimensional Stochastic Analysis Perspective
Interest Rate Models: an Infinite Dimensional Stochastic Analysis Perspective studies the mathematical issues that arise in modeling the interest rate term structure. These issues are approached by casting the interest rate models as stochastic evolution equations in infinite dimensions. The book is comprised of three parts. Part I is a crash course on interest rates, including a statistical analysis of the data and an introduction to some popular interest rate models. Part II is a self-contained introduction to infinite dimensional stochastic analysis, including SDE in Hilbert spaces and Malliavin calculus. Part III presents some recent results in interest rate theory, including finite dimensional realizations of HJM models, generalized bond portfolios, and the ergodicity of HJM models.
Intelligence and security informatics : Biosurveillance ; 2nd NSF Workshop, BioSurveillance 2007, New Brunswick, NJ, USA, May 22, 2007, Proceedings
The 2007 NSF BioSurveillance Workshop (BioSurveillance 2007) was built on the success of the first NSF BioSurveillance Workshop, hosted by the University of Arizona’s NSF BioPortal Center in March 2006.
Integrated Urban Water Resources Management
Growing populations and rising standards of living exert stress on water supply and the quality of drinking water. In wastewater management, new challenges are caused by new chemicals of concern, including endocrine disrupters, pharmaceuticals, hormones, and personal care products, which often pass through wastewater treatment plants unabated, but may cause serious impacts on receiving aquatic ecosystems. Advanced wastewater treatment leads to production of biosolids, which are processed in various ways, including on-land applications in agriculture. Municipal effluents, combined with increasing withdrawals of water, lead to the worsening of receiving water quality. Expert opinions indicate that the only way to deal with the current urban water management dilemmas is by integrated management and innovative delivery of water services. This book presents important aspects of Challenges in Management of Urban Water Resources, Challenges in Urban Water Supply, Urban Drainage and Water Bodies, Wastewater Treatment and Security, and Wastewater Treatment and Reuse.
Integrated Information Management : Applying Successful Industrial Concepts in IT
After years of apparent dormancy, once again companies are paying more att- tion to information management. IT departments and CIOs are confronted with a number of new challenges, which force them to reconsider past information m- agement strategies and solutions. Recently cited as positive trends in IT are only those developments concerning stronger customer service and process orientation or pertaining to new forms of IT governance.
Insulin Resistance and Polycystic Ovarian Syndrome : Pathogenesis, Evaluation, and Treatment
This book highlights the recent transition of PCOS from an infertility disorder with a diagnosis based on ovarian tissue histology to a more complex clinical entity, a metabolic disorder in which insulin resistance plays a central role. With an expert panel of authors, each chapter provides an up-to-date and balanced overview of PCOS, paying special attention to the central role of insulin resistance in the syndrome’s pathogenesis and in the management of its reproductive and metabolic abnormalities.
Innovative Internet Community Systems ; Vol. 3473 ; 4th International Workshop, IICS 2004, Guadalajara, Mexico, June 21-23, 2004. Revised Papers
This book constitutes the thoroughly refereed postproceedings of the 4th International Workshop on Innovative Internet Community Systems, IICS 2004, held in Guadalajara, Mexico, in June 2004. The 25 revised full papers presented together with 2 invited papers have been carefully reviewed. They focus mainly on system-oriented problems, text processing, and theoretical foundations of distributed and Internet systems. They also deal with speed and quality-of-service problems of Internet protocols, aspects of cooperation and collaboration in Internet systems, as well as agent and text-processing-based methods. In addition, 9 papers stem from two mini-workshops, one on computational epidemiology and the other on optimization of urban traffic systems.
Innovation : Center for Televion Radio and Contempo Rary Film
يهدف إنشاء الوجه الحديث إلى تجميع سلسلة من صور الوجه التي تتوافق مع مقطع الكلايبني المشروع نموذجًا محددًا لمظهر الوجه على موضوعات محددة ونماذج للتحول بين حركة الشفاه والكلام ، ويمتاز هذا التمثيل غير المتشابك بميزة حيث يمكن أن يكون الصوت والفيديو بمثابة مدخلات للجيل
Indian Agriculture Towards 2030 : Pathways for Enhancing Farmers’ Income, Nutritional Security and Sustainable Food and Farm Systems
The book comprises of ten contributions. Apart from the overview chapter on transformational change and the concluding chapter on pathways for 2030, there are eight thematic chapters on topics such as transforming Indian agriculture, dietary diversity for nutritive and safe food; climate crisis and risk management; water in agriculture; pests, pandemics, preparedness and biosecurity natural farming; agroecology and biodiverse futures; science, technology and innovation in agriculture; and structural reforms and governance.
In Vitro Culture of Mycorrhizas
biologists have made important progress in understanding better the functioning of AM fungi. An in vitro technique has been developed using mycorrhizal root organ cultures, which made it possible to investigate the genetics, cell biology and physiology of AM fungi. We can now be objective enough to critically evaluate the impacts the in vitro technique has had to improve our knowledge on mycorrhizal symbiosis.
Implementing machine learning for finance : A systematic approach to predictive risk and performance analysis for investment portfolios
Introduces pattern recognition and future price forecasting that exerts effects on time series analysis models, such as the Autoregressive Integrated Moving Average (ARIMA) model, Seasonal ARIMA (SARIMA) model, and Additive model, and it covers the Least Squares model and the Long Short-Term Memory (LSTM) model. It presents hidden pattern recognition and market regime prediction applying the Gaussian Hidden Markov Model. The book covers the practical application of the K-Means model in stock clustering. It establishes the practical application of the Variance-Covariance method and Simulation method (using Monte Carlo Simulation) for value at risk estimation. It also includes market direction classification using both the Logistic classifier and the Multilayer Perceptron classifier. Finally, the book presents performance and risk analysis for investment portfolios. You will: Understand the fundamentals of the financial market and algorithmic trading, as well as supervised and unsupervised learning models that are appropriate for systematic investment portfolio management / Know the concepts of feature engineering, data visualization, and hyperparameter optimization / Design, build, and test supervised and unsupervised ML and DL models / Discover seasonality, trends, and market regimes, simulating a change in the market and investment strategy problems and predicting market direction and prices / Structure and optimize an investment portfolio with preeminent asset classes and measure the / underlying risk
