الصفحة 38
الصفحة 38
Sparking Signals : Kinases as Molecular Signaltransducers and Pharmacological Drug Targets in Inflammation
Protein phosphorylation is an essential post-translational modification that modulates cell–cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups.
Spanish Economic Growth, 1850–2015
This text offers a comprehensive and nuanced view of the economic development of Spain since 1850. It provides a new set of historical GDP estimates for Spain from the demand and supply sides, and presents a reconstruction of production and expenditure series for the century prior to the introduction of modern national accounts. The author splices available national accounts sets over the period 1958–2015 through interpolation, as an alternative to conventional retropolation. The resulting national accounts series are linked to the historical estimates providing yearly series for GDP and its components since 1850.
Spaces of Holomorphic Functions in the Unit Ball
There has been a flurry of activity in recent years in the loosely defined area of holomorphic spaces. This book discusses the most well-known and widely used spaces of holomorphic functions in the unit ball of C^n. Spaces discussed include the Bergman spaces, the Hardy spaces, the Bloch space, BMOA, the Dirichlet space, the Besov spaces, and the Lipschitz spaces. Most proofs in the book are new and simpler than the existing ones in the literature. The central idea in almost all these proofs is based on integral representations of holomorphic functions and elementary properties of the Bergman kernel, the Bergman metric, and the automorphism group. The unit ball was chosen as the setting since most results can be achieved there using straightforward formulas without much fuss. The book can be read comfortably by anyone familiar with single variable complex analysis; no prerequisite on several complex variables is required. The author has included exercises at the end of each chapter that vary greatly in the level of difficulty.
Space, Movement, and Visibility in Pompeian Houses
Examines the pivotal role of movement, visibility, and experience within Pompeian houses as a major factor determining house form; the use of space; and the manner, meaning, and modalities of domestic daily life, through the application of GIS-based analysis. Through close consideration of ancient literature, detailed explanations of methodology, and exploration of results, Michael Anderson provides new perspectives on Pompeian domestic space including room types and household activities that rarely feature in the discussion of ancient housing. Readers gain a better understanding of priorities in the design of Pompeian houses, the degree to which daily life was interrupted by earthquake damage in the site’s final years, and evolving motivations behind wall painting decoration. The volume not only explores how Pompeian houses reflected the needs of everyday life as imagined by their architects, but also how these spaces served to influence and control daily activities and ultimately how they were transformed by the spatial and visual requirements of domestic life.
Space Weather : Research Towards Applications in Europe
This book shows the state of the art in Europe on a very new discipline, Space Weather. This discipline lies at the edge between science and industry. This book reflects such a position, with theoretic papers and applicative papers as well. It is divided into 5 chapters.
Space Shuttle Challenger : Ten Journeys into the Unknown
This book details the stories of Challenger's missions from the points of view of the astronauts, engineers, and scientists who flew and knew her and the managers, technicians, and ground personnel who designed her and nursed her from humble beginnings as a structural test article into one of the most capable Shuttles in NASA's service.
Space Planning Basics ; 4th ed.
Conquer the complexity of interior design with a logical, methodical approach. Shows you how to approach space planning in a way that ensures all considerations are met, and nothing gets lost in the process. Adopt an organized and comprehensive planning methodology / Work effectively with dimensionally challenging spaces / Consider building systems, codes, lighting, acoustics, and more / Develop advanced skills and conquer new challenges
Space Exploration 2008
Provides a yearly update on recent space launches, missions and results, to be published every September. The annual will cover space exploration from a variety of angles, looking back at past missions, reviewing those currently under way and detailing those planned for the future, and encompassing both manned and unmanned spaceflight. The invited contributions, authored by leading figures in astronomy and space exploration and which make up the bulk of the annual each year, will cover a variety of topics and are written to appeal to a wide readership. One feature introduced in the first volume ‘Solar System Log’ featuring the very latest in the exploration of the planets, their moons and small Solar System bodies, will be retained for Space Exploration 2008, and will comprise seven chapters. In addition, there will be a special additional section entitled, ‘Return to the Moon’ containing three chapters.
South-North Migration of EU Citizens in Times of Crisis
Identifies the scale and nature of this new Southern European emigration and examines these migrants’ socio-economic integration in Northern European destination countries. This is achieved through an analysis of the most recent data on flows and profiles of this new labour force using sending-country and receiving-country databases. Second, it looks at the politics and policies of immigration, both from the perspective of the sending- and receiving-countries.
Solid-State Fermentation Bioreactors : Fundamentals of Design and Operation
Although solid-state fermentation (SSF) has been practiced for many centuries in the preparation of traditional fermented foods, its application to newer products within the framework of modern biotechnology is relatively restricted. It was c- sidered for the production of enzymes in the early 1900s and for the production of penicillin in the 1940s, but interest in SSF waned with the advances in submerged liquid fermentation (SLF) technology. The current dominance of SLF is not s- prising: For the majority of fermentation products, it gives better yields and is e- ier to apply. It is notoriously difficult to control the fermentation conditions in SSF; these difficulties are already apparent at small scale in the laboratory and are exacerbated with increase in scale.
Solar-Type Activity in Main-Sequence Stars
In this monograph observational results are summarized in a systematic and comprehensive fashion. The analysis of the various manifestations of such stellar activity leads to the identification of these phenomena with macroscopic non-linear processes in a magnetized plasma. Comparative study of flare stars and the Sun has become increasingly fruitful and is presently an active field of research involving stellar and solar physicists, experts in plasma physics and high-energy astrophysicists. This book will provide them with both an introduction and overview of observational results from the first optical photometry and spectroscopy, from the satellite telescopes International Ultraviolet Explorer to Hubble Space Telescope, XMM-Newton and Chandra, as well as with the present physical interpretation of solar-type activity in main sequence stars. Gershberg's 40-year career studying UV Cet type stars and related objects enables him to provide readers with expert insight into the characteristics of such stars in both the quiescent state and during flares and the reliability of the data over the electromagnetic spectrum and wide temporal scales.
Solar Hydrogen Generation : Toward a Renewable Energy Future
Examines strategies for generating hydrogen from sunlight and water in a sustainable way. Authoritative discussions are provided by experts on topics ranging from a description of the solar resource, electrolysis of water, solar concentrator pathway to low cost electrolytic hydrogen, thermal/photo hybrid splitting of water, photochemical water splitting, hydrogen generation at inorganic semiconductor-electrolyte interfaces, to photobiological schemes for producing hydrogen from water. The book culminates with an analysis of a coupled water electrolyzer-solar photovoltaic system for the centralized production of hydrogen. The literature citation is extensive and comprehensive in each chapter and the book provides a broad perspective of the rapid developments in an important aspect of energy science and technology.
Solar Energy Fundamentals and Modeling Techniques : Atmosphere, Environment, Climate Change and Renewable Energy
Collects together material from the current literature in atmospheric environmental sciences, climate change research, meteorology, engineering and renewable energy, liberally illustrated by diagrams and worked examples.the book includes an innovative exposition of expert system methodologies used in the domain of solar irradiation and energy. In addition to methodologies such as statistics and geo-statistics (regionalized variables), new modeling approaches such as fuzzy logic inference, artificial neural network (ANN) and genetic algorithm techniques are introduced, along with both classical Kriging and newly developed techniques for spatial solar irradiation modeling.
Solar electric power generation - photovoltaic energy systems : Modeling of optical and thermal performance, electrical yield, energy balance, effect on reduction of greenhouse gas emissions
Professor Krauter demonstrates how the importance of accurate yield calculations, optimal system performance, and new prototypes aid in cost reductions. The potential of solar electric power generation as a means to significantly reduce CO2 emissions is also detailed. In addition, various locations for the production and installation of photovoltaic power plants are considered – with surprising results.
Solar Desalination for the 21st Century : A Review of Modern Technologies and Researches on Desalination Coupled to Renewable Energies
The countries affected by water scarcity are found in the African, Asian, European and American continents, and also are on the southern and eastern coasts of the Mediterranean Sea. Severe drought usually generates a general malaise in populations which are already affected by a number of social and poverty problems, which often lead to significant and uncontrolled emigration towards richer countries, especially if one takes into account the increasing economic and lifestyle gap between north and south Mediterranean countries.
Solar Architecture : Strategies, Visions, Concepts
Whether insulating glazing, multifunctional facades or organic solar cells, there have been important new developments in the areas of solar thermal technology, photovoltaics, heating and ventilation technology which can make a significant contribution to the conservation of natural resources in sustainable building. They are suitable for a wide range of uses from largescale urban-planning projects, to individual single family houses.
Solar and Space Weather Radiophysics : Current Status and Future Developments
Most of the chapters of this book are based on invited talks at the FASR Science Workshop, held in Greenbank, W Vin May 2002, and a special session on Solar and Space Weather Radiophysics held at the 200th American Astronomical Society meeting held in Albuquerque, NM in June 2002. Although many of the chapters deal with topics of interest in planning for FASR, other topics in Solar and Space Weather Radiophysics, such as solar radar and interplanetary scintillation, are covered to round out the discipline. The authors have been asked to write with a tutorial approach, to make the book useful to graduate students and scientists new to radio physics. This book is more than a compilation of FASR science topics. The FASR instrument concept is so revolutionary — by extending capability by an order of magnitude in several dimensions at once (frequency coverage, spatial resolution, dynamic range,time resolution,polarizationprecision)—that it challenges scientists to think in new ways.
Solar and Heat Pump Systems for Residential Buildings
Compares different systems, analyses their performance and illustrates monitoring techniques. It helps the reader to design, simulate and assess solar and heat pump systems. Good examples of built systems are discussed in detail and advice is given on how to design the most efficient system.
Soils of Volcanic Regions in Europe
Soils of volcanic areas often exhibit unique properties differentiating them from other soils on Earth. This publication compiles information gained by an EU research network over six years of research on European volcanic soils. The book gives comprehensive coverage of soils in volcanic regions within Europe, dealing with most aspects of modern day soil science. New methodology is introduced and the synthesis of the research casts a new light on soils with andic soil properties. It covers a range of issues such as mineralogy, chemistry, physics, biology, soil genesis, classification, land use and pollution.
Software-Intensive Systems and New Computing Paradigms : Challenges and Visions
The objective was to imagine the landscape in which next generations of software-intensive systems will operate and the challenges they present to computing, software engineering, cognition and intelligence. The volume starts with an overview of the current state of the art and the research missions in engineering software-intensive systems. The book is structured in three major parts: ensemble engineering, theory and formal methods, and novel computing paradigms. These papers cover a broad spectrum of relevant topics ranging from methods, languages and tools for ensemble engineering, socio-technical and cyber-physical systems, ensembles in urban environments, formal methods and mathematical foundations for ensembles, orchestration languages to disruptive paradigms such as molecular and chemical computing.
