الصفحة 341
الصفحة 341
Amartya Sens Capability Approach: Theoretical Insights and Empirical Applications
Kuklys examines how Nobel Prize-winning economist Amartya Sen’s approach to welfare measurement can be put in practice for poverty and inequality measurement in affluent societies such as the UK. Sen argues that an individual’s welfare should not be measured in terms of her income, but in terms what she can actually do or be, her capabilities. In Chapters 1 and 2, Kuklys describes the capability approach from a standard welfare economic point of view and provides a comprehensive literature review of the empirical applications in this area of research. In the remaining chapters, novel econometric techniques are employed to operationalise the concepts of functionings and capability to investigate inequality and poverty in terms of capability in the UK. Kuklys finds that capability measurement is always a useful complement to traditional monetary analysis, and particularly so in the case of capability-deprived disabled individuals.
Alzheimer's disease : Peptide vaccine and immunotherapy
Peptide vaccines and immunotherapies against aggregating proteins involved in the pathogenesis and progression of Alzheimer's disease (AD) the ẞ-amyloid peptide (Aẞ) and tau are promising therapeutic avenues against AD. Two decades of effort has led to the controversial United States Food and Drug Administration (FDA) approval of the monoclonal antibody Aducamumab (Aduhelm), which has subsequentially sparked the revival and expedited review of promising monoclonal antibody immunotherapies that target Aẞ.
Alzheimers Disease : Advances in genetics, molecular and cellular biology
Alzheimer’s Disease: Advances in Genetics, Cellular and Molecular Biology provides exciting, comprehensive and up-to-date summaries of the most important recent advances in the genetic, molecular, biochemical, and cell biological studies of AD. The studies and advances described in this volume will help to accelerate the process of rational drug discovery and soon serve to extend and enhance the mental health and lifespan of our burgeoning elderly population.
Alzheimer's Disease
Alzheimer is a disease which has not a cure yet, and about 10% of the population worldwide will suffer from it. However younger people may also develop this disease mainly at 45 years old mainly women who has double the rate of incidence since 1 if five women will certainly develop it. Therefore the goal of our research is to study first of all the history of such popular disease and its risk factors and current therapies or iagnostic tools and more important we will introduce a test which was discovered few months ago to predict the risk of developing Alzheimer few decades before it occurs and we will apply it in our laboratories in Syria as well. Beside this preventive test we will add also a very important diet to follow up by people who has a family history.
Alzheimers Disease
Alzheimer’s disease (AD) is a neurodegenerative disease that robs the minds of our elderly population. Approximately one in every eight adults over the age of 65 and nearly half of those over 85 are afflicted with this disease. The aging population in developed societies will impose an ever increasing socioeconomic threat in the future. Current medicines for AD patients are mainly symptomatic treatments and a huge unmet medical need exists to slow the progression of this disease. A great deal of research has been dedicated to understanding the pathogenesis of AD from which comes many ideas for intervening with its progression. Some of these ideas have been fast-tracked to clinical trials due to the availability of medicines with proven clinical efficacies for other diseases (e.g. atorvastatin, simvastatin, rosiglitazone and clioquinol) while others represent novel chemical entities (e.g. glycogen synthase kinase-3 inhibitors).
Alzheimer : 100 Years and Beyond
Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4th, 1906 in Tübingen. The celebratory event, "Alzheimer 100 Years and Beyond" organized on the initiative of the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen, at the very site of the original lecture, namely the Institute of Psychiatry at the University of Tübingen in Germany from November 2nd to 5th, 2006, was the highlight of the Alzheimer Year. Over the last century of Alzheimer research (1906-2006), remarkable progress has been achieved. Most of the authors of the major discoveries and the people involved in research in this field will present, during the meeting and in this volume, the pioneering research explaining the conditions under which they were conducted. The goal of this book is to honor the work accomplished, to summarize the most important knowledge and to provide material for the history of science.
Alvar Aalto Houses
Finnish architect and designer Alvar Aalto (1898-1976) designed nearly one hundred single-family houses. Aalto, who is also known for his furniture and glassware, worked in a unique style that blended modernism and traditional vernacular architecture. Authors Jari and Sirkkaliisa Jetsonen (Finnish Summer Houses) present twenty-six of Aalto's innovative residences—from small summer homes and postwar standardized housing to large housing complexes for industrial commissions—built between the 1920s to the 1960s.
Alternatives to Animal Testing : Proceedings of Asian Congress 2016
This book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs.
Alternative Splicing and Disease
Splicing of primary RNA transcript, i.e. removal of introns and joining of exons to produce mature mRNAs competent for translation into proteins, is a quasi-systematic step of gene expression in higher organisms. However, this process is not unequivocal but can follow alternate pathways. Alternative splicing of a given transcript can therefore yield several distinct mRNAs encoding as many different proteins. Its full biological significance has not been appreciated until it was recognized that alternative splicing is so general as to affect about 75% of all human genes. Therefore, alternative splicing not only vastly increases protein diversity but also offers numerous opportunities for aberrant splicing events with pathological consequences.
Alternative medicines for diabetes management : Advances in pharmacognosy and medicinal chemistry
Apart from diet and exercise, the strategic use of different classes of prescribed or non-prescribed xenobiotic compounds for the restoration of euglycemic levels in the body is well known. The ongoing rivalry between the recommended usage of allopathic medicines versus ayurvedic remedies has encouraged many researchers to focus their studies on thoroughly isolating and characterizing the extracts from different parts of plants and then evaluating their relative activities via in vitro, in vivo and in some cases clinical studies.
Alternative breast imaging : Four model-based approaches
Medical imaging has been transformed over the past 30 years by the advent of computerized tomography (CT), magnetic resonance imaging (MRI), and various advances in x-ray and ultrasonic techniques. An enabling force behind this progress has been the (so far) exponentially increasing power of computers, which has made it practical to explore fundamentally new approaches. In particular, what our group terms "model-based" modalities-which produce tissue property images from data using nonlinear, iterative numerical modeling techniques-have become increasingly feasible. Alternative Breast Imaging: Four Model-Based Approaches explores our research on four such modalities, particularly with regard to imaging of the breast: (1) MR elastography (MRE), (2) electrical impedance spectroscopy (EIS), (3) microwave imaging spectroscopy (MIS), and (4) near infrared spectroscopic imaging (NIS).
Altering nature ; Vol.2 : Religion, Biotechnology, and Public Policy
The two volumes of Altering Nature consider the complex ways that concepts of 'nature' and 'the natural' are understood and the relevance of those understandings to discussions of biotechnology.Volume Two, Religion, Biotechnology, and Public Policy, reviews recent religious and ethical analyses of four specific areas of biotechnology: assisted reproduction, genetic therapy and enhancement, human-machine incorporation, and biodiversity. It identifies and explores the richer normative themes that inform particular debates and suggests ways that policy choices in biotechnology may be illuminated by devoting greater attention to religious perspectives.
Allosteric Regulatory Enzymes
This book provides a logical introduction to the limits for enzyme function as dictated by the factors that are limits for life. This book presents a complete description of all the mechanisms used for changing enzyme acticity. Eight enzymes are used as model systems after extensive study of their mechanisms. Wherever possible, the human form of the enzyme is used to illustrate the regulatory features.
Allergy in Practice
This book reflects the rich personal experience of a German allergist with international training and reputation, who is active in immunology and allergy research and practice for almost 30 years. In this book, not only IgE-mediated allergic reactions are covered but all other kinds of allergies such as atopic eczema, contact dermatitis, drug eruptions, anaphylaxis and food allergies are equally represented as well as psychosomatic aspects and problems of environmental intolerances.
Allergic rhinitis
Allergic rhinitis is a very common disorder that affects people of all ages, peaking in the teenage years. It is frequently ignored, underdiagnosed, misdiagnosed, and mistreated, which not only is detrimental to health but also has societal costs. Although allergic rhinitis is not a serious illness, it is clinically relevant because it underlies many complications, is a major risk factor for poor asthma control, and affects quality of life and productivity at work or school. Management of allergic rhinitis is best when directed by guidelines. A diagnostic trial of a pharmacotherapeutic agent could be started in people with clinically identified allergic rhinitis; however, to confirm the diagnosis, specific IgE reactivity needs to be recorded.
Allelopathy : A Physiological Process with Ecological Implications
This book provides the reader relevant information about actual knowledge about the process of allelopathy, covering all aspects from the molecular to the ecological level. Special relevance is given to the physiological and ecophysiological aspects of allelopathy. Several ecosystems are studied and methodological considerations are taken into account in several different chapters. The book has been written to be useful both for Ph.D. students and for senior researchers, so the chapters include all necessary information to be read by beginners, but they also include a lot of useful information and discussion for the initiated.
Allelochemicals : Biological Control of Plant Pathogens and Diseases
This book is organized around the indication that allelochemicals can be employed for biological control of plant pathogens and plant diseases. Specifically, this volume focuses on (i) discovery and development of natural product based fungicides for agriculture, (ii) direct use of allelochemicals as well as indirect effects through cover crops and organic amendments for plant parasitic pest control and (iii) application of allelopathy in pest management.
Alla ricerca della via più breve : Un'avventura matematica = Finding the shortest way : A mathematical adventure
Il libro narra la vicenda di Rut, quindicenne, trasferitasi da poco in Germania con la famiglia, al seguito del padre che lavora per un’azienda internazionale produttrice di Software. Sarà proprio il padre a regalare a Rut un computer nuovo, mentre a scuola attraversa un periodo di crisi.E’ l’inizio di un’avventura. Nel computer è installato Vim: un programma che ascolta, capisce e risponde alle domande che la ragazza, inizialmente incredula, fa. Raccontata da Vim, la matematica prende una forma completamente nuova, sorprendente e affascinante.
All of Nonparametric Statistics
The goal of this text is to provide the reader with a single book where they can find a brief account of many, modern topics in nonparametric inference. The book is aimed at Master's level or Ph.D. level students in statistics, computer science, and engineering. It is also suitable for researchers who want to get up to speed quickly on modern nonparametric methods.This text covers a wide range of topics including: the bootstrap, the nonparametric delta method, nonparametric regression, density estimation, orthogonal function methods, minimax estimation, nonparametric confidence sets, and wavelets. The book has a mixture of methods and theory.
Alkaliphiles : Genetic properties and applications of enzymes
The pioneering work of Dr. Koki Horikoshi on the discovery, research and applications of alkaliphilic bacteria are described here in their entirety. The isolation, distribution and taxonomy of alkaliphilic microorganisms as well as their cell structure and physiology are discussed for a basic understanding of these entities. The molecular biology and genome sequencing of some alkaliphilic bacterial strains are also presented. Part II of the volume focuses on enzymes of alkaliphiles and their applications. These include alkaline proteases, starch-degrading enzymes and numerous others. Some of these enzymes are currently in wide commercial use as laundry detergent additives and in wastewater treatment. Alkaliphiles are a relatively recent field of research that will no doubt provide avenues to a wide range of further discoveries and applications for a new generation of workers in bioscience and technology.
