الصفحة 33
الصفحة 33
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Entry Inhibitors in HIV Therapy

The introductory chapters of this book present an overview of entry inhibitors, review current knowledge of how Env mediates entry, and discuss the challenge of genetic diversity in this region of the viral genome. Subsequent chapters feature current information on individual classes of entry inhibitors that target each step of the virus entry pathway, from attachment to membrane fusion. There is an emphasis on the complex determinants of entry inhibitor susceptibility, resistance mechanisms, the need for clinical phenotyping, and how these issues create new challenges for antiretroviral therapy. Encouraging pre-clinical studies of entry inhibitors as microbicidesare also discussed. The final chapters highlight the current status of entry inhibitors in clinical studies, the major milestone achieved with FDA approval of enfuvirtide, and review drug development, past and present.

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English for Everyone Junior Beginner's Practice Book : Look, Listen, Learn, and Practise

Featuring hundreds of exercises, this practice book tests all the vocabulary and grammar structures taught in the English for Everyone Junior: Beginner's Course, making use of a range of both familiar and new exercise mechanisms.

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End-to-End Quality of Service Over Heterogeneous Networks

The book presents mechanisms, protocols, and system architectures to achieve end-to-end Quality-of-Service (QoS) over heterogeneous wired/wireless networks in the Internet. Particular focus is on measurement techniques, traffic engineering mechanisms and protocols, signalling protocols as well as transport protocol extensions to support fairness and QoS. It shows how those mechanisms and protocols can be combined into a comprehensive end-to-end QoS architecture to support QoS in the Internet over heterogeneous wired/wireless access networks. Finally, techniques for evaluation of QoS mechanisms such as simulation and emulation are presented.

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Endophytic microbes: Isolation, identification, and bioactive potentials

Provides basic insight and protocols relating to endophytic microbes. Chapter are divided into five major sections detailing basic isolation, bioactive metabolites production. endophytism, isolation and identification of endophytes, bioactive potentials, and screening of metabolites.

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Endocrinology : Basic and Clinical Principles

For this new edition of Conn & Melmed's Endocrinology: Basic and Clinical Principles, a panel of distinguished scientists and clinicians has completely rewritten every chapter to reflect the latest advances in our understanding of the endocrine system. Maintaining the original goal of the first edition to integrate the basic science of endocrinology with its physiological and clinical principles, the authors have succinctly summarized in 450 pages the latest findings on hormone secretion and hormone action, as well as all of the most recent insights into the physiology and pathophysiology of hormonal disorders. Coverage extends across the entire spectrum of endocrinology-from mammalian cells, plants, and insects to animal models and human diseases-with much increased coverage of diabetes and metabolism. Highlights include cutting-edge discussions of appetite disorders, obesity, reproductive failure, control of thyroid function, hormone action in humans and the lower species, and the mechanisms subserving hormone secretion.

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Endocrine-Disrupting Chemicals : From Basic Research to Clinical Practice

This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians’ office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs.

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Encyclopedia of Molecular Pharmacology

It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.

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Encyclopedia of Molecular Pharmacology

Covers all aspects of pharmacology, from the chemistry of drugs and the biochemistry of drug targets to the clinical application of drugs, with emphasis on molecular mechanisms. It also includes techniques for describing the effects of drugs and characterizing drug targets. With over 2,000 entries and 350 detailed essays by leading experts, this book is also an up-to-date and important reference for scientists in fields outside pharmacology, students, health care workers, teachers, physicians, and laypersons.

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Emerging Organic Pollutants in Waste Waters and Sludge

Over the past fifteen years regulatory agencies have relied on their approaches to characterise and control the release of toxic substances into the aquatic environment: a GC/MS analysis for U.S. EPA designated 126 priority pollutants and 132 dangerous substances according to the European 76/464/CEE Directive and on the bioassays with aquatic bioorganisms. "Emerging Contaminants" correspond in most cases to irregulated contaminants, e.g. surfactants, pharmaceuticals and personal care products (PPCP), or gasoline additives. These two volumes, 5/I and 5/O, of this Handbook deal with the analytical, toxicological and environmental issues of these toxicants. Based on results of up-to-date research they give the reader a balanced view on this rapidly developing and complex subject.

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Emergency Vascular Surgery : A Practical Guide

The book provides detailed guidelines to any physician treating patients with emergency vascular disorders, such as ruptured abdominal aortic aneurysms, acute limb ischemia, vascular trauma, iatrogenic vascular injuries and complications to vascular surgery. It provides an introduction to vascular surgical operations and focuses on how to manage patients from the emergency ward through the urgent operation and all the way to the immediate postoperative period. Numerous figures illustrate the particular points in vascular techniques and diagnostic problems in the emergency situation.

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Emergence of Communication and Language

This volume brings together studies from diverse disciplines, showing how they can inform and stimulate each other. It includes work in linguistics, psychology, neuroscience, anthropology and computer science. New empirical work is reported on both human and animal communication, using some novel techniques that have only recently become viable. A principal theme is the importance of studies involving artificial agents, their contribution to the body of knowledge on the emergence of communication and language, and the role of simulations in exploring some of the most significant issues. A number of different synthetic systems are described, demonstrating how communication can emerge in natural and artificial organisms. Theories on the origins of language are supported by computational and robotic experiments. Worldwide contributors to this volume include some of the most influential figures in the field, delivering essential reading for researchers and graduates in the area, as well as providing fascinating insights for a wider readership.

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Elliptic Theory and Noncommutative Geometry : Nonlocal Elliptic Operators

This comprehensive yet concise book deals with nonlocal elliptic differential operators, whose coefficients involve shifts generated by diffeomorophisms of the manifold on which the operators are defined. The main goal of the study is to relate analytical invariants (in particular, the index) of such elliptic operators to topological invariants of the manifold itself. This problem can be solved by modern methods of noncommutative geometry. This is the first and so far the only book featuring a consistent application of methods of noncommutative geometry to the index problem in the theory of nonlocal elliptic operators. Although the book provides important results, which are in a sense definitive, on the above-mentioned topic, it contains all the necessary preliminary material, such as C*-algebras and their K-theory or cyclic homology.

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Electronic Postage Systems : Technology, Security, Economics

This book introduces a taxonomy of electronic postage systems and explains their security risks and countermeasures. The underlying cryptographic mechanisms are introduced and explained, and the industrial-scale electronic postage systems existing worldwide, are sorted out with respect to this taxonomy. The author also discusses privacy and anonymous mail, the state of standardization of electronic postage, and the process of security evaluation and testing of electronic postage systems. This volume including electronic postage designers of postal operators and standardization bodies, software and test engineers, software vendors integrating electronic postage solutions into their applications, security engineers and cryptography experts, and accredited test laboratories evaluating electronic postage systems.

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Electronic Noise and Interfering Signals

Electronic Noise and Interfering Signals" is a comprehensive reference book on noise and interference in electronic circuits, with particular focus on low-noise design. The first part of the book deals with mechanisms, modeling, and computation of intrinsic noise which is generated in every electronic device. The second part analyzes the coupling mechanisms which can lead to a contamination of circuits by parasitic signals and provides appropriate solutions to this problem. The last part contains more than 100 practical, elaborate case studies

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Electronic Irradiation of Foods : An Introduction to the Technology

Electronic Irradiation of Foods describes all the key aspects of electron accelerator technology in detail. It emphasizes the physical science and technology aspects of food irradiation using machine sources of ionizing radiation. The book provides significant technical depth for interested workers and present descriptive, introductory material that should help demystify technology for businessmen to make informed choices regarding important investments decisions.Introductory chapters summarize the effects of ionizing radiation on biological organisms and the organic compounds comprising foods, and give an overview of the food irradiation process. Subsequent chapters cover the details of the electron beam and x-ray energy deposition, electron accelerator technologies, beam scanning systems, material handling systems, shielding design, and process control considerations. Important appendices cover radiation dosimetry, induced radioactivity, and ozone generation.

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Electron transfer : Mechanisms and applications

Written by one of the top scientists in this field, this is a systematic overview of the fundamental concepts and powerful applications. The author presents the central theories and mechanisms in electron transfer, followed by several systems in nature where this is important, while also covering modern green applications.

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Electromagnetics in Biology

In this book, the authors intended to focus their effort on describing (1) biological responses of human and animals, both in vivo and in vitro methodologies, to magnetic and/or electromagnetic field exposure, (2) characteristics of effective fields, (3) hypotheses to explain possible mechanisms of interaction between the fields and cells, and (4) induced current in ELF and induced heat in RF fields as key interaction mechanisms. The readers can have the present-day comprehensive knowledge about biological responses to electromagnetic field exposure.

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Electrochemical processes and corrosion in reinforced concrete

Some reinforced concrete structures prematurely corrode as they age, with significant financial implications, but it is not immediately clear why some are more durable than others. This book looks at the various mechanisms for corrosion and how what seemed to be a relatively simple matter has become more complex the further it is understood due to the properties of concrete, steel and the way reinforced concrete structures are constructed. The significance of electrochemical processes is identified with recent research using new technology discussed.

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Electrical Diseases of the Heart : Genetics, Mechanisms, Treatment, Prevention

Electrical Diseases of the Heart is a thorough clinical reference on the current status of cardiac electrophysiological disease,emphasizing common and diverse clinical features. The latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology, and interventional therapies of various clinical arrhythmogenic entities are featured and discussed in terms of recent advances in basic and clinical science.

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Educational Decentralization : Asian Experiences and Conceptual Contributions

Decentralization and Education: Asian Experiences and Conceptual Contributions examines the specific ways in which decentralization policies have affected the structure and delivery of education in eleven Asian nations. Written by top scholars in the field, the case studies provide detailed and rich empirical evidence documenting the tensions as well as synchronisms between the ideas that form the basis of decentralization policy and the contexts into which they are introduced. The high quality of this collection essays and the careful attention to local contexts for implementation will make this book a must read for academics, policy planners, practitioners, and students of Asia.

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