الصفحة 3
الصفحة 3
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Micro and Nano Mechanical Testing of Materials and Devices

Nanoscale and nanostructured materials have exhibited different physical properties from the corresponding macroscopic coarse-grained materials due to the size confinement. As a result, there is a need for new techniques to probe the mechanical behavior of advanced materials on the small scales. Micro and Nano Mechanical Testing of Materials and Devices presents the latest advances in the techniques of mechanical testing on the micro- and nanoscales, which are necessary for characterizing the mechanical properties of low-dimensional materials and structures.

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Methods in Modern Biophysics

Incorporating recent dramatic advances, this textbook presents a fresh and timely introduction to modern biophysical methods. An array of new, faster and higher-power biophysical methods now enables scientists to examine the mysteries of life at a molecular level. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, proteomics, and protein folding and structure. Incorporating much information previously unavailable in tutorial form, Nölting employs worked examples and 267 illustrations to fully detail the techniques and their underlying mechanisms.

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Methods and Tools for Drought Analysis and Management

Implementation of effective drought management policies requires both advanced technologies and appropriate methods. Monitoring and forecasting systems, practical tools for risk assessment, as well as simple and objective criteria to select and implement appropriate drought mitigation measures are key elements for a successful drought management strategy.These key issues have been tackled by universities and public agencies involved in the EU projects Sedemed and Sedemed II (Programme Interreg IIIB MEDOCC), aimed at the definition of an integrated network for real time monitoring of drought, the development of common methodologies for drought analysis and forecasting, as well as the definition of proper mitigation strategies for the Mediterranean countries.The book presents the main outcomes of such projects with a special focus on: drought monitoring and forecasting echniques at different spatial scales; new or modified agrometeorological indices and remote sensing technique for drought identification and characterization; tools to improve surface water resources management under drought conditions; methods and tools for groundwater resources monitoring and management, based on hydrogeological and hydrodynamics characteristics of aquifers; general criteria to select and implement mitigation strategies to prevent or minimize drought impacts.

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Metastasis of Breast Cancer

The book has covered a broad range of topics in the metastasis of breast cancer, from genetics, biology to clinical management. Main topics include genetic control, biology, growth factors, cell adhesion, cell motility and invasion, natures of bone metastasis, sentinel node therapies, hormonal links, new biomarkers and detection of micrometastasis, and diagnosis The book also covers the current treatment options including surgical management, chemotherapy and hormonal therapies.

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Metabolomics : The frontier of systems biology

Metabolism is the sum of the chemical reactions in cells that produce life-sustaining chemical energy and metabolites. In the post-genome era, metabolism has taken on new significance for biological scientists: metabolites are the chemical basis of phenotypes that are final expressions of genomic information. This book covers research on metabolomics, ranging from the development of specialized chemical analytical techniques to the construction of databases and methods for metabolic simulation. The authors have been directly involved in the development of all the subject areas, including capillary electrophoresis, liquid chromatography, mass spectrometry, metabolic databases, and metabolic simulation. Breakthrough achievements and the future of metabolome studies are described, making this book a valuable source for researchers in metabolomics in diverse fields, such as plant, animal, cellular, microbial, pharmaceutical, medical, and genetic sciences.

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Metabolome Analyses : Strategies for Systems Biology

Metabolome Analyses is intended as a follow-up to Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis (Kluwer, 2003). That text offered guidelines to currently available technology, bioinformatics and databases. Evidence was presented showing metabolic profiling as a valuable addition to genomics and proteomics strategies devoted to drug discovery and development. This book focuses on how metabolic profiling is being more comprehensively integrated with the other "omics" technologies. It provides more practical applications of such "panomics" or "Systems Biology" approaches. The expanding use of mass spectrometry as a measurement technology in metabolic profiling is addressed through demonstrated applications. The integration of metabolic profiling and proteomics is probably most developed for plant-based studies, which was not addressed in Volume 1. Other areas related to metabolic profiling continue to show significant development. These include database strategies and an increased acceptance by the pharmaceutical industry of metabolic profiling. Also covered is the use of in silico metabolic networks. Again the focus is primarily on the pharmaceutical industry but the importance of metabolic profiling to studies on human nutrition (a burgeoning area) is discussed.

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Mercury Pollution in Minamata

It overviews the poisoning which occurred in the 1950s and 1960s among the residents in Minamata who ate seafood contaminated with methylmercury discharged from the chemical factory, Chisso Corporation. It describes the history, symptoms pathogenesis and research on the causal agent, and discusses the responses of Chisso and the national and local governments to the outbreak, the victims, the compensation and environmental restructuring as well as the court ruling on claims. Based on lecture notes from a university course, it includes students’ suggestions for avoiding a repeat of the tragedy. The issue has not been settled yet, and this analysis of the incident provides useful insights into solutions to the current global mercury pollution problem.

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MEMS/NEMS : (1) Handbook Techniques and Applications Design Methods, (2) Fabrication Techniques, (3) Manufacturing Methods, (4) Sensors and Actuators, (5) Medical Applications and MOEMS

Micro-Electro Mechanical Systems (MEMS) is the integration of mechanical elements, sensors, actuators, and electronics on a common silicon substrate. While the electronics are fabricated using integrated circuit (IC) process sequences (e.g., CMOS, Bipolar, or BICMOS processes),the micromechanical components are fabricated using compatible micromachining processes that selectively etch away parts of the silicon wafer or add new structural layers to form the mechanical and electromechanical devices. MEMS promises to revolutionize nearly every product category by bringing together silicon-based microelectronics with micromachining technology, thereby, making possible the realization of complete systems-on-a-chip.

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Mechatronics : Dynamics of Electromechanical and Piezoelectric Systems

Deals with Lagrange equations for electromechanical systems, including piezoelectric transducers and selected applications. Intended for the research community and graduate students at the MSc and PhD level, this book is an extension to piezoelectric systems of the work, ""Dynamics of Mechanical and Electromechanical Systems"", published in 1968.

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Mechanisms of Insulin Action

More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. In addition, between 17 and 40 million people have insulin resistance, impaired glucose tolerance, or the cluster of abnormalities referred to variably as the metabolic syndrome, the dysmetabolic syndrome, syndrome X, or the insulin resistance syndrome. In all of these disorders, a central component of the pathophysiology is insulin resistance, i.e., reduced responsiveness to insulin in tissues such as muscle, fat and liver. Insulin resistance is also closely linked to other common health problems, including obesity, polycystic ovarian disease, hyperlipidemia, hypertension, and atherosclerosis. In this book, we will attempt to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. We explore insulin action at the most basic levels, through complex systems. The book will be appealing to basic and clinical scientists.

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Mechanics of Microelectromechanical Systems

This book offers a comprehensive coverage to the mechanics of microelectromechanical systems (MEMS), which are analyzed from a mechanical engineer’s viewpointelectric energy.

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Mayo clinic infectious disease case review : With board-style questions and answers

Addresses many of the current-day illnesses seen by primary care clinicians and infectious diseases specialists. A case presentation format is used for all 54 chapters, and this framework serves as a wonderful educational tool that mirrors, in many respects, the objectives of a “case conference” format. The dozens of authors from different areas of our specialty have ensured that a robust clinical examination of specific infection syndromes has been included. In addition, the Question and Answer section solidifies the educational benefits for all levels and types of clinicians who seek an understanding of disease diagnosis, management, and prevention. A well-recognized characteristic of infectious diseases specialists is our focus on epidemiology, and this trait has served us well in developing successful clinical careers.

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Irritable Bowel syndrome I.B.S

Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder with a range of symptoms that significantly affect quality of life for patients. Is currently one of the most common disorders of the digestive system in the Western society? Almost 2 out of 10 people suffer from IBS, and it is associated with abdominal pain, bloating and altered stool consistency and imposes a heavy burden for the affected patients. The difficulty of differential diagnosis and its treatment may significantly delay initiation of optimal therapy. Hence, persons with IBS often self-treat symptoms with non-prescribed pharmacological regimens and/or complementary and alternative medicines (CAM) and by modifying diet and daily activities.

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International Cooperation for Enhancing Nuclear Safety, Security, Safeguards and Non-proliferation–60 Years of IAEA and EURATOM ; Proceedings of the XX Edoardo Amaldi Conference, Accademia Nazionale dei Lincei, Rome, Italy, October 9-10, 2017

Examines key aspects of international cooperation to enhance nuclear safety, security, safeguards, and non-proliferation, thereby assisting in development and maintenance of the verification regime and fostering progress toward a nuclear weapon-free world. The book opens by addressing important political, institutional, and legal dimensions. Current challenges are discussed and attempts made to identify possible solutions and future improvements. Subsequent sections consider scientific developments that have the potential to increase the effectiveness of implementation of international regimes, particularly in critical areas, technology foresight, and the ongoing evaluation of current capabilities. The closing sections examine scientific and technical challenges and discuss the role of international cooperation and actions of the scientific community in leading the world toward peace and security.

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International Cooperation for Enhancing Nuclear Safety, Security, Safeguards and Non-proliferation ; Proceedings of the XXI Edoardo Amaldi Conference, Accademia Nazionale dei Lincei, Rome, Italy, October 7–8, 2019

This book examines key aspects of international cooperation to enhance nuclear safety, security, safeguards, and nonproliferation, thereby assisting in development and maintenance of the verification regime and fostering progress toward a nuclear weapon-free world.

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International aviation law for aerodrome planning

The objective of to provide ICAO, States, competent authorities and aerodrome operators with a comprehensive overview of legal challenges related to international aerodrome planning. Answers to derived legal questions as well as recommendations thereafter shall help to enhance regulatory systems and to establish a safer aerodrome environment worldwide. Compliant aerodrome planning has an immense impact on the safety of passengers, personnel, aircraft – and of course the airport.

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Interferometry and Synthesis in Radio Astronomy

This book is open access under a CC BY-NC 4.0 license.The third edition of this indispensable book in radio interferometry provides extensive updates to the second edition, including results and technical advances from the past decade; discussion of arrays that now span the full range of the radio part of the electromagnetic spectrum observable from the ground, 10 MHz to 1 THz; an analysis of factors that affect array speed; and an expanded discussion of digital signal-processing techniques and of scintillation phenomena and the effects of atmospheric water vapor on image distortion, among many other topics.

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Integration of Insect-Resistant Genetically Modified Crops within IPM Programs

The goal of this book is to provide an overview on the role insect-resistant GM plants play in different crop systems worldwide. We hope that the book will contribute to a more rational debate about the role GM crops can play in IPM for food and fiber production.

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Insulin Resistance and Polycystic Ovarian Syndrome : Pathogenesis, Evaluation, and Treatment

This book highlights the recent transition of PCOS from an infertility disorder with a diagnosis based on ovarian tissue histology to a more complex clinical entity, a metabolic disorder in which insulin resistance plays a central role. With an expert panel of authors, each chapter provides an up-to-date and balanced overview of PCOS, paying special attention to the central role of insulin resistance in the syndrome’s pathogenesis and in the management of its reproductive and metabolic abnormalities.

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Insulin resistance

Insulin is a peptide hormone secreted by the B cells of the pancreatic islets of Langerhans and maintains normal blood glucose levels by facilitating cellular glucose uptake, regulating carbohydrate, lipid and protein metabolism and promoting cell division and growth through its mutagenic effects.

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