Alternative Splicing and Disease
Splicing of primary RNA transcript, i.e. removal of introns and joining of exons to produce mature mRNAs competent for translation into proteins, is a quasi-systematic step of gene expression in higher organisms. However, this process is not unequivocal but can follow alternate pathways. Alternative splicing of a given transcript can therefore yield several distinct mRNAs encoding as many different proteins. Its full biological significance has not been appreciated until it was recognized that alternative splicing is so general as to affect about 75% of all human genes. Therefore, alternative splicing not only vastly increases protein diversity but also offers numerous opportunities for aberrant splicing events with pathological consequences.
Algorithmic Foundation of Robotics VII : Selected Contributions of the 7th International Workshop on the Algorithmic Foundations of Robotics
This book contains the proceedings from the 2006 Workshop on the Algorithmic Foundations of Robotics. The 32 papers in this book span a wide variety of topics: from fundamental motion planning algorithms to applications in medicine and biology, but they have in common a foundation in the algorithmic problems of robotic systems.
Ajax Patterns and Best Practices
Ajax is taking us into the next generation of web applications. Ajax has broken the client-server barrier by decoupling the client from the server, but an Ajax application still needs a server to extract content from. The most effective use of Ajax and the server requires an understanding of REST, an architectural style used to define Web services. Ajax Patterns and Best Practices explores dynamic web applications that combine Ajax and REST as a single solution. A major advantage of REST is that, like Ajax, it can be used with today's existing technologies.
Ajax in Oracle JDeveloper
The book covers web search and RSS Feed with Ajax as well as form validation with Ajax frameworks for Java, JSP, JSF, and PHP. It discusses using Ajax in Oracle JDeveloper and is IDE based. JDeveloper has the following advantages over Eclipse IDE.
Aging and the Heart : A Post-Genomic View
In this book, the genetic and molecular basis of cardiovascular aging will be discussed. In addition, a comprehensive assessment of the bioenergetic changes that occur in human and animal models of cardiac aging as well as current diagnostic and future therapeutic modalities will be undertaken.
Aging and Senescence
Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. This deterioration is the primary risk factor for major human pathologies, including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases. Aging research has experienced an unprecedented advance over recent years, particularly with the discovery that the rate of aging is controlled, at least to some extent, by genetic pathways and biochemical processes conserved in evolution. Although recent developments in molecular biology are far from understanding the biological basis of aging, research suggests that targeting the aging process itself could ameliorate many age-related pathologies.
Aging and Chronic Disorders
Aging and Chronic Disorders brings the most up-to-date answers into clear, readable focus. Focusing on the most prevalent conditions affecting older adults (diabetes, cardiovascular disease, cancer, osteoporosis, osteoarthritis, rheumatoid arthritis, low back pain, and fibromyalgia), Morewitz and Goldstein analyze disabilities and risk factors, stressors and coping strategies, treatment and rehabilitation methods, and patient education and self-management. Separate chapters are devoted to cognitive changes, psychological problems, and trends in health care utilization among seniors, and all chapters are amplified by current research findings and instructive case studies. As in their recent work.
Aesthetic Facial Surgery
Rhytidoplasty is a palliative procedure in which face wrinkles are surgically removed to promote a more youthful appearance.The first sections focus on the surgical planning, including psychological considerations, preparation of the patient and anatomical and biochemical changes caused by the aging process. It also describes the surgical anatomy of the forehead, face, neck and eyelids. The third section provides a comprehensive overview of the basic techniques of facelift with details of refined surgical approaches for each segment of the face and neck. It highlights liposuction techniques, lipoinjection as well as transference of stem cells, showing their importance in reshaping the facial contours. It addresses both the treatment of soft tissue and craniofacial bone structures to improve the aesthetics of the face. The next sections present the final scars after face-lifting, minimally invasive procedures as complementary approaches during rhytidoplasty and the associated procedures during rhytidoplasty. The last section discusses postoperative care.
Adverse Food Reaction
Adverse food reaction is a broad term indicating a link between an ingestion of a food and an abnormal response. Adverse reactions to foods, aside from those considered toxic, are caused by a particular individual intolerance towards commonly tolerated foods. Intolerance derived from an immunological mechanism is referred to as Food Allergy, the non-immunological form is called Food Intolerance. IgE-mediated food allergy is the most common and dangerous type of adverse food reaction. It is initiated by an impairment of normal Oral Tolerance to food in predisposed individuals (atopic). Food allergy produces respiratory, gastrointestinal, cutaneous and cardiovascular symptoms but often generalized, life-threatening symptoms manifest at a rapid rate-anaphylactic shock.
Advances in web mining and web usage analysis ; 8th International workshop on knowledge discovery on the web, WebKDD 2006 Philadelphia, USA, August 20, 2006 Revised Papers
The discipline of data mining delivers methodologies and tools for the an- ysis of large data volumes and the extraction of comprehensible and non-trivial insights from them. Web mining, a much younger discipline, concentrates on the analysisofdata pertinentto the Web.Web mining methods areappliedonusage data and Web site content; they strive to improve our understanding of how the Web is used, to enhance usability and to promote mutual satisfaction between e-business venues and their potential customers.Many ofthe infancy problems in Web mining have been solvedby now, but the tremendous potential for new and improved uses, as well as misuses, of the Web are leading to new challenges.
Advances in Targeted Cancer Therapy
This volume is the first book to cover the general topic of targeted cancer therapy. It presents a range of targets such as tumor angiogenesis, cell cycle control and cell signalling, COX-2, apoptosis/cell survival, invasion and metastasis and approaches like kinase inhibitors, antisense, and antibody-based therapeutics. The emphasis is on preclinical development, including target validation, development of biomarkers, strategies for combination approaches, and development of resistance. The particular challenges involved in translating these data to clinical application are discussed.
Advances in pervasive computing and networking
"Pervasive Computing and Networking aim at providing ubiquitous, ever-present, adaptable, smart, enveloping and immersive environments in which computing components and humans can interact regardless of the location. The combination of an abundance of computational power of the processors and the communication bandwidth provided by the wireless and mobile networking everywhere and all the time makes such environments within the reach of current technology. Yet, to realize the full potential of such environments, many technical and economical challenges needs to be overcome. These challenges and the perspective on the seminal directions of the research in this area were the subject of the Workshop for Pervasive Computing and Networking at Rensselaer Polytechnic Institute, Troy, NY, USA.
Advances in information retrieval ; 30th European Conference on IR Research, ECIR 2008, Glasgow, UK, March 30-April 3, 2008. Proceedings
This book constitutes the refereed proceedings of the 30th annual European Conference on Information Retrieval Research, ECIR 2008, held in Glasgow, UK, in March/April 2008.
Advances in grid and pervasive computing ; 3rd International Conference, GPC 2008, Kunming, China, May 25-28, 2008. Proceedings
This book constitutes the refereed proceedings of the Third International Conference on Grid and Pervasive Computing, GPC 2008, held in Kunming, China, in May 2008.
Advances in grid and pervasive computing ; 2nd International Conference, GPC 2007, Paris, France, May 2-4, 2007, Proceedings
This book address all aspects of grid and pervasive computing and focus on topics such as cluster computing, high performance computing, grid computing, semantic Web and semantic grid, service-oriented computing, peer-to-peer computing, pervasive computing, mobile computing, network storage, as well as grid and pervasive related applications.
Advances in grid and pervasive computing ; 1st International Conference, GPC 2006, Taichung, Taiwan, May 3-5, 2006, Proceedings
This book constitutes the refereed proceedings of the First International Conference on Grid and Pervasive Computing, GPC 2006, held in Taichung, Taiwan, in May 2006.The 64 revised full papers were carefully reviewed and selected from 267 submissions. The papers are organized in topical sections on grid scheduling, peer-to-peer computing, Web/grid services, high performance computing, ad hoc networks, wireless sensor networks, grid applications, data grid, pervasive applications, semantic Web, semantic grid, grid load balancing, wireless ad hoc/sensor networks, and mobile computing.
Advances in flavonoids for human health and prevention of diseases
In response to the recent upsurge of interest in the therapeutic potential of medicinal plants, with their promising phenolic compounds, this new book offers an important overview of advances in the applications of flavonoids for health. The book explores the nutritional and pharmacological properties of polyphenols and flavonoids, including their ability to prevent the start and development of diseases and how they aid in the management of several chronic pathological illnesses, including cancer, diabetes, cardiovascular disease, neuro-degenerative illness and aging, pregnancy-induced disorders, and others. Also discussed in depth are the properties, classes, and degrees that formulate a phenolic compound and which subsequently supports the development of drugs/products with health benefits.
Advances in Evolutionary Computing for System Design
Evolutionary computing paradigms offer robust and powerful adaptive search mechanisms for system design. This book includes thirteen chapters covering a wide area of topics in evolutionary computing and applications including: -Introduction to evolutionary computing in system design - Evolutionary neuro-fuzzy systems - Evolution of fuzzy controllers - Genetic algorithms for multi-classifier design -Evolutionary grooming of traffic -Evolutionary particle swarms -Fuzzy logic systems using genetic algorithms - Evolutionary algorithms and immune learning for neural network-based controller design - Distributed problem solving using evolutionary learning -Evolutionary computing within grid environment -Evolutionary game theory in wireless mesh networks - Hybrid multiobjective evolutionary algorithms for the sailor assignment problem - Evolutionary techniques in hardware optimization
Advances in Electromagnetic Fields in Living Systems ; Vol.4
Advances in Electromagnetic Fields in Living Systems , Volume 4 begins with fetal magnetocardiography (fMCG), a noninvasive method of detecting components of the magnetic field produced by the electrical activity of the fetal heart. FMCG is experiencing steady growth, and is expected to gain influence in diagnosing certain congenital fetal heart defects while at the same time providing optimal care for patients. FMCG provides a distinct signal, free of maternal cardiac interference, which can be detected throughout the last half of pregnancy.
Advances in Electrical and Computer Technologies ; Select Proceedings of ICAECT 2019
Contains the papers presenting the latest developments in the areas of Electrical, Electronics, Communication systems and Computer Science such as smart grids, soft computing techniques in power systems, smart energy management systems, power electronics, feedback control systems, biomedical engineering, geo informative systems, grid computing, data mining, image and signal processing, video processing, computer vision, pattern recognition, cloud computing, pervasive computing, intelligent systems, artificial intelligence, neural network and fuzzy logic, broad band communication, mobile and optical communication, network security, VLSI, embedded systems, optical networks and wireless communication.



















