An introduction to pharmacovigilance ; 2nd ed.
Designed to aid the rapid understanding of the key principles of pharmacovigilance. Packed full of examples illustrating drug safety issues it not only covers the processes involved, but the regulatory aspects and ethical and societal considerations of pharmacovigilance. Covering the basics step-by-step, this book is perfect for beginners and is essential reading for those new to drug safety departments and pharmaceutical medicine students. The second edition is thoroughly revised and updated throughout and includes a new chapter on clinical aspects of pharmacovigilance.
An Introduction to Ordinary Differential Equations
This textbook provides a rigorous and lucid introduction to the theory of ordinary differential equations (ODEs), which serve as mathematical models for many exciting real-world problems in science, engineering, and other disciplines.
An Introduction to Optical Wireless Mobile Communications
Discusses existing conventional radio frequency (RF)-based wireless access technology and presents the challenges that can impact the requirements of the future wave of new wireless services in the context of artificial intelligence (AI) driven autonomous systems and machine-type communications. The relationship between visible light communications (VLC) and light fidelity (LiFi), is explored, and the major advantages of VLC and LiFi such as security and data density, and discuss existing research challenges are also introduced. Channel modeling techniques are provided for mobile multiuser scenarios, and will introduce key building blocks to achieve LiFi cellular networks achieving orders of magnitude improvements of area spectral efficiency compared to state-of-the-art. Challenges that arise from moving from a static point-to-point visible light link to a LiFi network that is capable of serving hundreds of mobile and fixed nodes are discussed. An overview of recent standardization activities and the commercialization challenges of this disruptive technology is also provided.
An introduction to ontology engineering
Provides the reader with a comprehensive introductory overview of ontology engineering. A secondary aim is to provide hands-on experience in ontology development that illustrate the theory. The book is divided into three blocks: Block I: logic foundations for ontologies both regarding the languages (mainly First Order predicate Logic, Description Logics, and OWL) and automated reasoning. Block II: developing good ontologies with methods and methodologies, the top-down approach with foundational ontologies, and the bottom-up approach to extract as much useful content as possible from legacy material. Block III: advanced topics with a selection of areas of specialisation, including Ontology-Based Data Access, the interaction between ontologies and natural languages (multilingual ontologies, controlled natural language), and advanced modelling with additional language features (fuzzy and temporal ontologies)
An Introduction to Number Theory
An Introduction to Number Theory provides an introduction to the main streams of number theory. Starting with the unique factorization property of the integers, the theme of factorization is revisited several times throughout the book to illustrate how the ideas handed down from Euclid continue to reverberate through the subject. In particular, the book shows how the Fundamental Theorem of Arithmetic, handed down from antiquity, informs much of the teaching of modern number theory. The result is that number theory will be understood, not as a collection of tricks and isolated results, but as a coherent and interconnected theory. A number of different approaches to number theory are presented, and the different streams in the book are brought together in a chapter that describes the class number formula for quadratic fields and the famous conjectures of Birch and Swinnerton-Dyer. The final chapter introduces some of the main ideas behind modern computational number theory and its applications in cryptography.
An Introduction to Network Programming with Java
This book provides an overview of Java … . Each chapter is supplemented with practical programming exercises.The combination of code templates with good supporting discussions allows a competent Java programmer to rapidly expand his or her skill base to include network programming.
An Introduction to Meshfree Methods and Their Programming
This book aims to present meshfree methods in a friendly and straightforward manner, so that beginners can very easily understand, comprehend, program, implement, apply and extend these methods. It provides first the fundamentals of numerical analysis that are particularly important to meshfree methods. Typical meshfree methods, such as EFG, RPIM, MLPG, LRPIM, MWS and collocation methods are then introduced systematically detailing the formulation, numerical implementation and programming. Many well-tested computer source codes developed by the authors are attached with useful descriptions. The application of the codes can be readily performed using the examples with input and output files given in table form. These codes consist of most of the basic meshfree techniques, and can be easily extended to other variations of more complex procedures of meshfree methods. Readers can easily practice with the codes provided to effective learn and comprehend the basics of meshfree methods.
An introduction to medicinal chemistry
Providing an introduction to medicinal chemistry, this resource covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug
An Introduction to Mathematics of Emerging Biomedical Imaging
Biomedical imaging is a fascinating research area to applied mathematicians. Challenging imaging problems arise and they often trigger the investigation of fundamental problems in various branches of mathematics. This is the first book to highlight the most recent mathematical developments in emerging biomedical imaging techniques. The main focus is on emerging multi-physics and multi-scales imaging approaches. For such promising techniques, it provides the basic mathematical concepts and tools for image reconstruction. Further improvements in these exciting imaging techniques require continued research in the mathematical sciences, a field that has contributed greatly to biomedical imaging and will continue to do so.
An Introduction to Mathematical Cryptography
This self-contained introduction to modern cryptography emphasizes the mathematics behind the theory of public key cryptosystems and digital signature schemes. The book focuses on these key topics while developing the mathematical tools needed for the construction and security analysis of diverse cryptosystems. Only basic linear algebra is required of the reader; techniques from algebra, number theory, and probability are introduced and developed as required.
An Introduction to Markov Processes
Provides a more accessible introduction than other books on Markov processes by emphasizing the structure of the subject and avoiding sophisticated measure theoryLeads the reader to a rigorous understanding of basic theory
An Introduction to Language Processing with Perl and Prolog : An Outline of Theories, Implementation, and Application with Special Consideration of English, French, and German
This book teaches the principles of natural language processing, first covering linguistics issues such as encoding, entropy, and annotation schemes; defining words, tokens and parts of speech; and morphology. It then details the language-processing functions involved, including part-of-speech tagging using rules and stochastic techniques; using Prolog to write phase-structure grammars; parsing techniques and syntactic formalisms; semantics, predicate logic and lexical semantics; and analysis of discourse, and applications in dialog systems. The key feature of the book is the author's hands-on approach throughout, with extensive exercises, sample code in Prolog and Perl, and a detailed introduction to Prolog. The reader is supported with a companion website that contains teaching slides, programs, and additional material.
An Introduction to Infinite-Dimensional Analysis
In this revised and extended version of his course notes from a 1-year course at Scuola Normale Superiore, Pisa, the author provides an introduction – for an audience knowing basic functional analysis and measure theory but not necessarily probability theory – to analysis in a separable Hilbert space of infinite dimension.Starting from the definition of Gaussian measures in Hilbert spaces, concepts such as the Cameron-Martin formula, Brownian motion and Wiener integral are introduced in a simple way. These concepts are then used to illustrate some basic stochastic dynamical systems (including dissipative nonlinearities) and Markov semi-groups, paying special attention to their long-time behavior: ergodicity, invariant measure. Here fundamental results like the theorems of Prokhorov, Von Neumann, Krylov-Bogoliubov and Khas'minski are proved. The last chapter is devoted to gradient systems and their asymptotic behavior.
An Introduction to Global Spectral Modeling
Numerical weather prediction is receiving increased attention as weather forecasters aim to improve the numerical models used to forecast the weather. This is a textbook on global spectral modeling, which is an important component for global weather forecasts at numerous operational centers. This book covers all areas of model development including numerical analysis, treatment of clouds, mountains, radiation, precipitation processes, and the surface layers over land and the ocean. The objectives of this book are to provide a systematic and sequential background for students, researchers, and operational weather forecasters in order to develop comprehensive weather forecast models. This is designed for a one semester introductory graduate level course on weather prediction methodologies. As a prerequisite it requires a basic background in meteorology, applied mathematics, and numerical analysis.
An introduction to generative drug discovery
Describes the state‑of‑the‑art methods and applications for de novo design of drug candidates using generative chemistry models as well as the ethical aspects of this technology. It will provide a foundation for those new to the field as well as those that may already have some experience of its utility. With contributions from scientists in both academia and industry ‘Introduction to Generative Drug Discovery’ may represent one of the earliest if not the first book to focus on this topic.
An Introduction to Formal Languages and Automata
Designed for an introductory course on formal languages, automata, compatibility, and related matters forming what is known as the theory of computation
An Introduction to Ethics in Robotics and AI
This book provides an introduction into the ethics of robots and artificial intelligence. The book was written with university students, policy makers, and professionals in mind but should be accessible for most adults. The book is meant to provide balanced and, at times, conflicting viewpoints as to the benefits and deficits of AI through the lens of ethics. As discussed in the chapters that follow, ethical questions are often not cut and dry. Nations, communities, and individuals may have unique and important perspectives on these topics that should be heard and considered. While the voices that compose this book are our own, we have attempted to represent the views of the broader AI, robotics, and ethics communities.
An Introduction to Efficiency and Productivity Analysis
It is designed to be a "first port of call" for people wishing to study efficiency and productivity analysis. The book provides an accessible introduction to the four principal methods involved: econometric estimation of average response models; index numbers; data envelopment analysis (DEA); and stochastic firontier analysis (SFA). For each method, we provide a detailed introduction to the basic concepts, give some simple numerical examples, discuss some of the more important extensions to the basic methods, and provide references for further reading. In addition, we provide a number of detailed empirical applications using real-world data.
An Introduction to Echo Analysis : Scattering Theory and Wave Propagation
The use of various types of wave energy is an increasingly promising, non-destructive means of detecting objects and of diagnosing the properties of quite complicated materials. An analysis of this technique requires an understanding of how waves evolve in the medium of interest and how they are scattered by inhomogeneities in the medium. These scattering phenomena can be thought of as arising from some perturbation of a given, known system and they are analysed by developing a scattering theory. This monograph provides an introductory account of scattering phenomena and a guide to the technical requirements for investigating wave scattering problems.
An Introduction to Difference Equations
The book integrates both classical and modern treatments of difference equations. It contains the most updated and comprehensive material, yet the presentation is simple enough for the book to be used by advanced undergraduate and beginning graduate students. This third edition includes more proofs, more graphs, and more applications. The author has also updated the contents by adding a new chapter on Higher Order Scalar Difference Equations, along with recent results on local and global stability of one-dimensional maps, a new section on the various notions of asymptoticity of solutions, a detailed proof of Levin-May Theorem, and the latest results on the LPA flour-beetle model



















