الصفحة 24
الصفحة 24
Hepatitis Delta Virus ; Vol. 307
Since its discovery nearly 30 years ago, hepatitis delta virus (HDV) has continued to surprise and fascinate. At 1,680 nucleotides the HDV genome is the smallest known to infect man. It is unique among animal viruses, the closest known relatives being plant viroids. To compensate for its limited protein coding capacity, HDV relies heavily on host functions and on structural features of its circular RNA genome. HDV infection depends on hepatitis B virus as a helper, and increases the severity of liver disease caused by HBV alone. There is currently neither an effective HDV vaccine nor a generally accepted useful therapy for HDV infection. This volume encompasses recent developments in HDV research, from molecular virology to genetics to experimental investigation of new therapeutic and vaccine candidates.
Hepatitis Delta Virus ; Medical Intelligence Unit (MIUN)
Hepatitis Delta Virus is an up-to-date guide to hepatitis D virus (HDV), a human virus with a number of distinctive features. Each chapter of this book describes one of the broad aspects of HDV from virology to molecular biology, and from diagnosis to therapy.
Hepatitis C virus-host interactions and therapeutics : Current insights and future perspectives
The burden of hepatitis C virus (HCV) infection on the public health care system continues to remain significant despite the remarkable progress made in HCV therapeutics in the recent past. There are now almost a dozen oral interferon-free direct-acting antivirals available for the treatment of hepatitis C virus infection. Despite advances in the treatment of HCV, therapeutic gaps remain that are yet to be fully explored. Researchers and scientists still strive to understand virus-host interactions to map the disease’s progression along with extrahepatic manifestations and virus invasion strategies impacting the host’s immune system. This book briefly discusses the biology of HCV infection, virus-host interactions, molecular epidemiology of the infection, and the full spectrum of immune responses to hepatitis C. It also provides in-depth information about HCV, clinical diagnostics, and therapeutic knowledge to all stakeholders involved in HCV screening, diagnosis, treatment, and management.
Hepatitis C Virus Disease
Emphasizes the most recent advances on the Hepatitis C virus infection (HCV) moving from basic research to clinical application. In spite of the numerous studies on HCV infection, its pathogenesis and medical treatment have not been fully explained. The first chapters of this volume analyize the full spectrum of immune responses to HCV taking into account either innate or adoptive immunity involvement. The volume also includes a series of contributions which explain the state of art of IFN-alpha treatment in HCV patients and the effectiveness of therapy also in relation to HCV genotypes. The use and applications of pegylated IFNs will also be discussed as well as the complicated HCV disease and its treatment. Hepatitis C Virus Disease: Immunobiology and Clinical Applications is an ideal volume for researchers, scientists, professionals, clinicians, physicians and graduate students in the fields of infectious disease, immunology, virology, microbiology, pharmacology and medicine.
Hedgehog-Gli Signaling in Human Disease
Hedgehog-GLI Signaling in Human Disease represents the first compilation of up-to-date reviews by top-level scientists in this important field of research. The chapters cover a wide spectrum of related interests, from the molecular bases of morphogen function, to human genetics to cancer research. The aim of the book is to disseminate information on this exciting field, to allow students, scientists and the public in general to gain access current information from research leaders and to provide a book that encompasses different aspects of research showing the fusion of basic research in model systems and medicine. This is a timely primer on how a system of cell communication, Hedgehog-GLI signaling, plays a critical role in human disease and thus provides the background for the development of novel and rational therapies.
Heat Shock Proteins in Cancer
Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery.
Heat Shock Proteins and the Brain : Implications for Neurodegenerative Diseases and Neuroprotection
Neurodegenerative disorders such as Alzheimer’s disease, Huntington’s disease, Parkinson’s disease and amyotrophic lateral sclerosis have been termed ‘protein misfolding disorders’ that are char- terized by the neural accumulation of protein aggregates. Manipulation of the cellular stress response involving the induction of heat shock proteins offers a the- peutic strategy to counter conformational changes in neural proteins that trigger pathogenic cascades resulting in neurodegenerative diseases. Heat shock proteins are protein repair agents that provide a line of defense against misfolded, aggregati- prone proteins. Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection reviews current progress on neural heat shock proteins (HSP) in relation to neurodegenerative diseases (Part I), neuroprotection (Part II), ext- cellular HSP (Part III) and aging and control of life span (Part IV).
Heat shock proteins : Potent mediators of inflammation and immunity
Written by leaders in the field of heat shock protein immunobiology, the chapters systematically and in a step wise fashion takes the reader through the fascinating sequence of events by which heat shock proteins activate immune responses and provides answers as to its biological significance to the host.
Hearing and Sound Communication in Amphibians
Hearing and Sound Communication in Amphibians is a compendium of the latest research on acoustic communication in these highly vocal vertebrates. The chapters are written by experts currently investigating the physiology and behavior of amphibians both in the laboratory and in the field. This integrated approach guides each chapter and provides a neuroethologically-driven and evolutionary basis for our understanding of acoustic communication and its underlying mechanisms. The intended audience ranges from senior undergraduates to physiologists, zoologists, evolutionary biologists and communication specialists.
Hearing : From Sensory Processing to Perception
Hearing – From Sensory Processing to Perception presents the papers of the latest International Symposium on Hearing. The 59 chapters treat topics such as: the physiological representation of temporal and spectral stimulus properties as a basis for the perception of modulation patterns, pitch and signal intensity; spatial hearing and the physiological mechanisms of binaural processing in mammals.
Healthcare solutions using machine learning and informatics
Covers novel and innovative solutions for the healthcare that apply machine learning and biomedical informatics technology. The healthcare sector is one of the most critical in society. This book presents a series of artificial intelligence, machine learning, intelligent IoT-based solutions for medical image analysis, medical big data processing, disease predictions. Machine learning and artificial intelligence use cases in healthcare presented in the book give researchers, practitioners, and students a wide range of practical examples of cross-domain convergence. The wide variety of topics covered include: Artificial Intelligence in healthcare Machine learning solutions for such disease as diabetes, arthritis, cardiovascular disease, and COVID-19 Big data analytics solutions for healthcare data processing Reliable biomedical applications using AI models Intelligent IoT in healthcare. The book explains fundamental concepts as well as the advanced use cases illustrating how to apply emerging technologies such as machine learning, AI models, data informatics into practice to tackle challenges in the field of healthcare with real-world scenarios. Chapters contributed by noted academicians and professionals examine various solutions, frameworks, applications, case studies, and best practices in the healthcare domain
Health information systems : Technological and management perspectives
Details a variety of scenarios in the context of both health and heath care, including where prevention and wellness are related, such as the treatment of both acute and chronic diseases. Stakeholder requirements are also described to provide perspectives for describing the architectures and management techniques associated with health information systems, enabling the reader to develop a detailed holistic overview of the subject. Health Information Systems: Technological and Management Perspectives features a detailed overview of how information systems in health care can be managed and is a vital resource for medical informatics students seeking an up-to-date text on the topic.
Health Information Science ; 9th International Conference, HIS 2020, Amsterdam, The Netherlands, October 20–23, 2020, Proceedings
This book constitutes the proceedings of the 9th International Conference on Health Information Science, HIS 2020, which took place in Amsterdam, The Netherlands, during October 20-23, 2020. The 11 full papers and 6 short papers presented in this volume were carefully reviewed and selected from 62 submissions. They were organized in topical sections named: mental health; medical record processing; medical information systems; medical diagnosis with machine learning; and health behavior and medication.
Health Communication
The effective communication of information on medical conditions and healthy lifestyles has played an important part in the improvement of the health status of the American population. At the same time, it is hard to ignore the negative impact that ineffective communication can have within the healthcare arena.communication. The benefits of good health communication are many, from better relationships between providers and patients to improved treatment compliance to reduced inequities of care.
HCI and usability for medicine and health care ; 3rd Symposium of the Workgroup Human-computer interaction and usability engineering of the Austrian Computer Society, USAB 2007 Graz, Austria, November, 22, 2007, Proceedings
The work group Human–Computer Interaction & Usability Engineering (HCI&UE) of the Austrian Computer Society (OCG) serves as a platform for interdisciplinary exchange, research and development. Our 2007 topic was “Human–Computer Interaction for Medicine and Health Care” (HCI4MED), Medical information systems are already extremely sophisticated and technological performance increases exponentially.
Harvesting Operations in the Tropics
The book brings together information on harvest methods, system productivity, and methods for conducting safe, efficient, and environmentally acceptable operations in tropical forests. It highlights the challenges of harvest operations in the tropics, includes techniques that have been shown to be successful, and discusses newer technologies.
Harty’s endodontics in clinical practice
A guide to proven, current clinical endodontic practice. It is designed, primarily, with the undergraduate readership in mind but is also suitable for anyone pursuing specialist training, including extended skills in endodontics, and general dental practitioners undertaking CPD, or wishing to keep up-to-date. The seventh edition is available with an online question bank containing MCQs and Clinical Cases.
Harnessing the Power of the Criminal Corpse
This book is the culmination of many years of research on what happened to the bodies of executed criminals in the past. Focusing on the eighteenth and nineteenth centuries, it looks at the consequences of the 1752 Murder Act. These criminal bodies had a crucial role in the history of medicine, and the history of crime, and great symbolic resonance in literature and popular culture. Starting with a consideration of the criminal corpse in the medieval and early modern periods, chapters go on to review the histories of criminal justice, of medical history and of gibbeting under the Murder Act, and ends with some discussion of the afterlives of the corpse, in literature, folklore and in contemporary medical ethics. Using sophisticated insights from cultural history, archaeology, literature, philosophy and ethics as well as medical and crime history, this book is a uniquely interdisciplinary take on a fascinating historical phenomenon.
Harmful Cyanobacteria
The purpose of this work is to provide an up-to-date overview of the advances in our knowledge of harmful cyanobacteria. The work is directed towards graduate students and scientists in aquatic microbiology, aquatic ecology, environmental toxicology, and water management, and academic professionals in water management and environmental policy.
Haploids in Crop Improvement II
This volume provides an excellent overview of haploid induction and the application of doubled haploids. The authors emphasize advances made in the understanding of microspore embryogenesis, but treat also advances in gynogenesis and the manipulation of parthenogenetic haploid development. The text contains a thorough discussion of the application of haploidy to the improvement of a number of species from various families.
