الصفحة 21
الصفحة 21
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Molecular Basis of Symbiosis

Symbiotic associations involving prokaryotes occur ubiquitously and are ecologically highly significant. In symbiotic associations, co-evolution of the partner organisms has led to specific mechanisms of signal exchange and reciprocal regulation, and resulted in novel physiological capabilities of the association as compared to those of the individual partners. Symbiosis research has recently entered an exciting era because molecular biology techniques are available for studying partner organisms in association and in a culture-independent manner. It is the goal of this book to contribute towards a broader perspective and an understanding of the function of symbiotic systems. 14 different model systems have been chosen, comprising well known symbioses as well as novel experimental systems which have only recently become amenable to experimental manipulation.

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Molecular autoimmunity

The autoimmune disease paroxysmal cold hemoglobinuria, a rare hemolytic disorder. After a century of research, the list of autoimmune diseases has become impressive. With a prevalence of approximately 5% of the world-wide population, these chronic, debilitating conditions affect almost every major organ of the body and, for reasons that remain unclear, are much more prevalent in woman than in men. Despite our rapidly expanding knowledge of the cellular and molecular pathways that govern a normal immune response, deciphering the precise etiology of autoimmune diseases remains an important challenge. Over the last few years, our understanding of the pathogenesis of autoimmune diseases has improved rapidly, leading to the emergence of elegant immunointervention strategies. Molecular Autoimmunity illustrates how cutting-edge research is continuing to advance our understanding of autoimmune disease mechanisms and identifies novel therapeutic targets that provide a hope for effective future treatments. This volume contains a selected number of exciting advances in unraveling autoimmune reactions, and the resulting new armory of experimental immunotherapies that may lead to new ways of controlling autoimmune reactions.

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Molecular analysis of B lymphocyte development and activation

The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation. In addition new insights became available for the processes of B cell activation, class switch recombination and somatic hypermutation. Many of the new findings and their implications for a molecular understanding of B cell biology in particular and cell differentiation in general are covered in this volume.

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Modules and Comodules

The 23 articles in this volume encompass the proceedings of the International Conference on Modules and Comodules held in Porto (Portugal) in 2006 and dedicated to Robert Wisbauer on the occasion of his 65th birthday. These articles reflect Professor Wisbauer's wide interests and give an overview of different fields related to module theory, some of which have a long tradition whereas others have emerged in recent years. They include topics in the formal theory of modules bordering on category theory, in ring theory, in Hopf algebras and quantum groups, and in corings and comodules.

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Modular Forms

It provides the reader with the basic knowledge of elliptic modular forms necessary to understand the recent developments in number theory. The first part gives the general theory of modular groups, modular forms and Hecke operators, with emphasis on the Hecke-Weil theory of the relation between modular forms and Dirichlet series. The second part is on the unit groups of quaternion algebras, which are seldom dealt with in books. The so-called Eichler-Selberg trace formula of Hecke operators follows next and the explicit computable formula is given. In the last chapter, Eisenstein series with parameter are discussed following the recent work of Shimura: Eisenstein series are likely to play a very important role in the future progress of number theory, and this chapter provides a good introduction to the topic.

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Modular Algorithms in Symbolic Summation and Symbolic Integration

Brings together two streams in computer algebra: symbolic integration and summation on the one hand, and fast algorithmics on the other hand. In many algorithmically oriented areas of computer science, the analysis of al gorithms placed into the lime light by DonKnuth’stalkat the 1970ICM –provides a crystal-clear criterion for success. The researcher who designs an algorithm that is faster (asymptotically, in the worst case) than any previous method receives instant gratification : her result will be recognized as valuable. Al as, the downside is that such results come along quite infrequently, despite our best efforts. An alternative evaluation method is to run a new algorithm on examples; this has its obvious problems, but is sometimes the best we can do. George Collins, one of the fathers of computer algebra and a great experimenter,wrote in 1969: “I think this demonstrates again that a simple analysis is often more revealing than a ream of empirical data (although both are important). ” Within computer algebra, some areas have traditionally followed the former methodology, notably some parts of polynomial algebra and linear algebra. Other areas, such as polynomial system solving, have not yet been amenable to this - proach. The usual “input size” parameters of computer science seem inadequate, and although some natural “geometric” parameters have been identified (solution dimension, regularity), not all (potential) major progress can be expressed in this framework. Symbolic integration and summation have been in a similar state.

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Modernizing the academic teaching and research environment : Methodologies and cases in business research

Constitutes a valuable manual for young and seasoned business researchers alike, and provides a comprehensive summary for the whole research journey. It is a must-read for all researchers who need to understand the basics of business research, from identifying research topics, to planning and organizing the research process, and selecting the most appropriate methodology for the topic at hand. This book also provides insights on how to avoid common pitfalls in business research and outlines the research skills needed to write a fine piece of research. In order to capture the innovative element of research, the book also highlights methods for thinking outside the box. It also stresses the importance of respecting ethics while conducting business research. Lastly, it presents important cases and provides hands-on training for preparing survey tools. Readers looking to master business research won’t want to miss out on this unique and insightful book.

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Modern Trends in Pseudo-Differential Operators

The ISAAC Group in Pseudo-diferential Operators (IGPDO) was formed at the Fourth ISAAC Congress held at York University in Toronto in 2003 and the Frst volume entitled Advances in Pseudo-di?erential Operators and devoted to papers focussing on pseudo-di?erential operators and its diverse applications was then initiated and published in Professor Israel Gohberg’s series Operator Theory: - vances and Applications in 2004.The vision is to seek new directionsfor the broadsubjectonpseudo-diferentialoperatorsand the strategy is to devote the Catania Volume not only to papers based on lectures given at the special session on pseudo-diferential operators, but also invited - pers that bear on the themes of IGPDO.

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Modern Theatres 1950–2020

Explores in detail 30 of the most significant theatres, concert halls, opera houses and dance spaces that opened between 1950 and 2010. Each theatre is reviewed and assessed by experts in theatre buildings, such as architects, acousticians, consultants and theatre practitioners, and illustrated with full-colour photographs and comparative plans and sections. A further 20 theatres that opened from 2009 to 2020 are concisely reviewed and illustrated. An excellent resource for students of theatre planning, theatre architecture and architectural design, Modern Theatres 1950 – 2020 discusses the role of performing arts buildings in cities, explores their public and performances spaces and examines the acoustics and technologies needed in a great building. This beautifully illustrated book is also a must-read for architects, theater designers, theatre historians, and theatre practitioners.

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Modern Testing Techniques for Structural Systems : Dynamics and Control

The articles in this book describe new developments in the area of structural testing, particularly those based upon the principle of fusing numerical and experimental methods such as real-time dynamic substructuring and hardware-in-the loop testing. In addition to the hybrid methods, chapters on the latest develoments in more established techniques, such as shaking table testing, provide a completely up-to-date survey of structural testing methods.

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Modern structural analysis : Modelling process and guidance

Essential reading for 21st century practitioners and students who need to do structural analysis. It contains a great deal of information that is not available in any other book on the subject. This is because the conventional view of structural analysis is rooted in the early part of the 20th century in the pre-computer era rather than present time.

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Modern Sliding Mode Control Theory : New Perspectives and Applications

This book is a collection of invited chapters covering several areas of modern sliding mode control theory. The authors identify key contributions defining the theoretical and applicative state of the art of the sliding mode control theory and the most promising trends of the ongoing research activities. The contributions is divided in four main parts: Part I: Basic Theory. Part II: Design Methods. Part III: Observers and Fault Detection. Part IV: Applications.

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Modern parallel programming with C++ and assembly language : X86 SIMD development using AVX, AVX2, and AVX-512

Understand the essential details about x86 SIMD architectures and instruction sets including AVX, AVX2, and AVX-512. / Master x86 SIMD data types, arithmetic instructions, and data management operations using both integer and floating-point operands. / Code performance-enhancing functions and algorithms that fully exploit the SIMD capabilities of a modern x86 processor. Employ C++ intrinsic functions and x86-64 assembly language code to carry out arithmetic calculations using common programming constructs including arrays, matrices, and user-defined data structures. Harness the x86 SIMD instruction sets to significantly accelerate the performance of computationally intense algorithms in applications such as machine learning, image processing, computer graphics, statistics, and matrix arithmetic. / Apply leading-edge coding strategies and techniques to optimally exploit the x86 SIMD instruction sets for maximum possible performance.

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Modern Optical Spectroscopy : With Exercises and Examples from Biophysics and Biochemistry

This textbook offers clear explanations of the theory of optical spectroscopic phenomena and shows how these ideas are used in modern molecular and cellular biophysics and biochemistry. The topics covered include electronic and vibrational absorption, fluorescence, resonance energy transfer, exciton interactions, circular dichroism, coherence and dephasing, ultrafast pump-probe and photon-echo spectroscopy, single-molecule and fluorescence-correlation spectroscopy, Raman scattering, and multiphoton absorption.

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Modern Operative Dentistry : Principles for Clinical Practice

Provides the theoretical knowledge required by students when learning how to diagnose oral diseases, plan treatment, and perform various types of dental restoration. It is also useful for clinicians wishing to update their treatment skills and broaden their understanding operative dentistry. Adopting an evidence-based approach, and in accordance with the philosophy of minimally invasive dentistry, it explains in detail the use of both classic and new restorative materials in various clinical situations. It also discusses the principles of smile analysis, as well the technique for esthetic composite restorations on posterior and anterior teeth, including direct and indirect veneers.

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Modern Morphometrics in Physical Anthropology

Morphometrics has undergone a revolutionary transformation in the past two decades as new methods have been developed to address shortcomings in the traditional multivirate analysis of linear distances, angles, and indices. While there is much active research in the field, the new approaches to shape analysis are already making significant and ever-increasing contributions to biological research, including physical anthropology. Modern Morphometrics in Physical Anthropology highlights the basic machinery of the most important methods, while introducing novel extensions to these methods and illustrating how they provide enhanced results compared to more traditional approaches. Modern Morphometrics in Physical Anthropology provides a comprehensive sampling of the applications of modern, sophisticated methods of shape analysis in anthropology, and serves as a starting point for the exploration of these practices by students and researchers who might otherwise lack the local expertise or training to get started. This text is an important resource for the general morphometric community that includes ecologists, evolutionary biologists, systematists, and medical researchers.

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Modern Methods in the Calculus of Variations : L^p Spaces

This is the first of two books on methods and techniques in the calculus of variations. Contemporary arguments are used throughout the text to streamline and present in a unified way classical results, and to provide novel contributions at the forefront of the theory.This book addresses fundamental questions related to lower semicontinuity and relaxation of functionals within the unconstrained setting, mainly in L^p spaces. It prepares the ground for the second volume where the variational treatment of functionals involving fields and their derivatives will be undertaken within the framework of Sobolev spaces.

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Modern medicines from plants : Botanical histories of some of modern medicine’s most important drugs

Features information on plants from which we obtain modern prescription medicines. It outlines their historical uses as herbal medicines in the past two millennia, using primary sources, and describes how extracts from them, and their semisynthetic and synthetic derivatives, were developed to be today’s therapeutic drugs and diagnostic chemicals. This book describes medicinal plants and their habitats, the diseases that their medicines treat, and the science of how they work.

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Modern Mathematics Education for Engineering Curricula in Europe : A Comparative Analysis of EU, Russia, Georgia and Armenia

Provides a comprehensive overview of the core subjects comprising mathematical curricula for engineering studies in five European countries and identifies differences between two strong traditions of teaching mathematics to engineers. The collective work of experts from a dozen universities critically examines various aspects of higher mathematical education.

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Modern Magnetic Resonance ; Part 1 : Applications in Chemistry, Biological and Marine Sciences ; Part 2 : Applications in Medical and Pharmaceutical Sciences ; Part 3 : Applications in Materials Science and Food Science

Modern Magnetic Resonance provides a unique and comprehensive resource on up-to-date uses and applications of magnetic resonance techniques in the sciences, including chemistry, biology, materials, food, medicine, pharmaceuticals and marine sciences.The widespread appeal of MMR methods for revealing information at the molecular and microscopic levels is noted and examples are provided from the chemical and other sciences.Until now, there has been no single publication that covers all the areas encompassed by "Modern Magnetic Resonance", by bringing together the various techniques and their applications in many scientific areas, the internationally renowned Editors have created a resource of broad appeal to the scientific community.

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