الصفحة 20
الصفحة 20
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Angiogenesis in Inflammation : Mechanisms and Clinical Correlates

This volume relates the lessons learned from tumour biology applied to inflammation. This issue of Angiogenesis in Inflammation: Mechanisms and Clinical Correlates develops current knowledge on the mechanisms at the molecular and cellular levels as they relate to inflammation, including acute and chronic inflammation, neurogenic initiation, and the role of the multiple cellular components that comprise inflammation: granulocytes, macrophages, fibroblasts, dendritic cells and lymphocytes. This is related to inflammatory disease: not only the familiar angiogenesis dependent diseases of rheumatoid arthritis and psoriasis, but also loci such as the lung, gastric ulcers, the eye with uveitis, wound healing and periodontal disease and their therapy, how this knowledge may be used in the discovery of novel therapeutics. The volume brings together experts in each of these fields to link the molecular and cellular processes in angiogenesis to those of inflammation and disease, culminating in a discourse on areas for future therapies.

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Analogy in Indian and western philosophical thought

This book was assembled from numerous excerpts, notes, and fragments according to his initial plans. Zilberman’s legacy still awaits its true discovery and this book is a second installment to it after The Birth of Meaning in Hindu Thought (Kluwer, 1988). Zilberman’s treatment of analogy is unique in its approach, scope, and universality for Western philosophical thought.

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An introduction to generative drug discovery

Describes the state‑of‑the‑art methods and applications for de novo design of drug candidates using generative chemistry models as well as the ethical aspects of this technology. It will provide a foundation for those new to the field as well as those that may already have some experience of its utility. With contributions from scientists in both academia and industry ‘Introduction to Generative Drug Discovery’ may represent one of the earliest if not the first book to focus on this topic.

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Ambient intelligence for scientific discovery : Foundations, theories, and systems

Many difficult scientific discovery tasks can only be solved in interactive ways, by combining intelligent computing techniques with intuitive and adaptive user interfaces. It is inevitable to use human intelligence in scientific discovery systems: human eyes can capture complex patterns and relationships, along with detecting the exceptional cases in a data set; the human brain can easily manipulate perceptions to make decisions. Ambient intelligence is about this kind of ubiquitous and autonomous human interaction with information. Scientific discovery is a process of creative perception and communication, dealing with questions like: how do we significantly reduce information while maintaining meaning, or how do we extract patterns from massive data and growing data resources. Originating from the SIGCHI Workshop on Ambient Intelligence for Scientific Discovery, this state-of-the-art survey is organized in three parts: new paradigms in scientific discovery, ambient cognition, and ambient intelligence systems. Many chapters share common features such as interaction, vision, language, and biomedicine.

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Alzheimers Disease : Advances in genetics, molecular and cellular biology

Alzheimer’s Disease: Advances in Genetics, Cellular and Molecular Biology provides exciting, comprehensive and up-to-date summaries of the most important recent advances in the genetic, molecular, biochemical, and cell biological studies of AD. The studies and advances described in this volume will help to accelerate the process of rational drug discovery and soon serve to extend and enhance the mental health and lifespan of our burgeoning elderly population.

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Allelochemicals : Biological Control of Plant Pathogens and Diseases

This book is organized around the indication that allelochemicals can be employed for biological control of plant pathogens and plant diseases. Specifically, this volume focuses on (i) discovery and development of natural product based fungicides for agriculture, (ii) direct use of allelochemicals as well as indirect effects through cover crops and organic amendments for plant parasitic pest control and (iii) application of allelopathy in pest management.

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Alkaliphiles : Genetic properties and applications of enzymes

The pioneering work of Dr. Koki Horikoshi on the discovery, research and applications of alkaliphilic bacteria are described here in their entirety. The isolation, distribution and taxonomy of alkaliphilic microorganisms as well as their cell structure and physiology are discussed for a basic understanding of these entities. The molecular biology and genome sequencing of some alkaliphilic bacterial strains are also presented. Part II of the volume focuses on enzymes of alkaliphiles and their applications. These include alkaline proteases, starch-degrading enzymes and numerous others. Some of these enzymes are currently in wide commercial use as laundry detergent additives and in wastewater treatment. Alkaliphiles are a relatively recent field of research that will no doubt provide avenues to a wide range of further discoveries and applications for a new generation of workers in bioscience and technology.

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Algorithms and Models for the Web-Graph ; 4th International Workshop, WAW 2006, Banff, Canada, November 30 - December 1, 2006. Revised Papers

his book constitutes the revised papers of the Fourth International Workshop on Algorithms and Models for the Web-Graph, WAW 2006, held in Banff, Canada, November 30 - December 1, 2006.

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Algorithmic learning theory ; Vol.4264 : 17th International Conference, ALT 2006, Barcelona, Spain, October 7-10, 2006, Proceedings

This book constitutes the refereed proceedings of the 17th International Conference on Algorithmic Learning Theory, ALT 2006, held in Barcelona, Spain in October 2006, colocated with the 9th International Conference on Discovery Science, DS 2006.The 24 revised full papers presented together with the abstracts of five invited papers were carefully reviewed and selected from 53 submissions. The papers are dedicated to the theoretical foundations of machine learning.

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Algorithmic learning theory ; 19th International Conference, ALT 2008, Budapest, Hungary, October 13-16, 2008. Proceedings

This book constitutes the refereed proceedings of the 19th International Conference on Algorithmic Learning Theory, ALT 2008, held in Budapest, Hungary, in October 2008, co-located with the 11th International Conference on Discovery Science, DS 2008.

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AiREAS : Sustainocracy for a healthy city : Phase 3 : Civilian participation – Including the global health deal proposition

This volume describes phase 3 of the AiREAS multidisciplinary cocreation effort to produce a Healthy City. Phase 1 referred to making visible the invisible from an air quality and human exposure perspective. Phase 2 studies air quality related to health and Phase 3 looks at air quality, health and lifestyle from the perspective of persuasion to innovative change. The three books together describe the coming about and first results of the AiREAS "healthy city" cooperative in the city of Eindhoven and Province of North Brabant in the Netherlands. AiREAS is an initiative focused on the multidisciplinary co-creation of healthy cities using the core human value of human health and air quality as guiding principle for profound regional innovation.

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AI in drug discovery

Constitutes the refereed proceedings of the First international workshop on ai in Drug Discovery, AIDD 2024, held as a part of the 33rd International Conference on Artificial Neural Networks, ICANN 2024, in Lugano, Switzerland, on September 19, 2024. These papers focus on various aspects of the rapidly evolving field of Artificial Intelligence (AI)-driven drug discovery in chemistry, including Big Data and advanced Machine Learning, eXplainable AI (XAI), Chemoinformatics, Use of deep learning to predict molecular properties, Modeling and prediction of chemical reaction data and Generative models.

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AI 2008 : Advances in artificial intelligence ; 21st Australasian Joint Conference on Artificial Intelligence Auckland, New Zealand, December 1-5, 2008. Proceedings

This book constitutes the refereed proceedings of the 21th Australasian Joint Conference on Artificial Intelligence, AI 2008, held in Auckland, New Zealand, in December 2008.

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AI 2007: Advances in artificial intelligence ; 20th Australian Joint Conference on Artificial Intelligence, Gold Coast, Australia, December 2-6, 2007, Proceedings

The book is organized in topical sections on machine learning, neural networks, evolutionary computing, constraint satisfaction, satisfiability, automated reasoning, knowledge discovery, robotics, social intelligence, ontologies and semanti.

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AI 2006 : Advances in artificial intelligence ; 19th Australian Joint Conference on Artificial Intelligence, Hobart, Australia, December 4-8, 2006, Proceedings

This volume contains the proceedings of the 19th Australian Joint Conference on Artificial Intelligence (AI 2006) held at Hobart, Australia. AI 2006 received a record number of submissions, a total of 689 submissions from 35 countries. The papers in this volume give an indication of recent advances in artificial int- ligence. The topics covered include Machine Learning, Robotics, AI Applications, Planning, Agents, Data Mining and Knowledge Discovery, Cognition and User Interface, Vision and Image Processing, Information Retrieval and Search, AI in the Web, Knowledge Representation, Knowledge-Based Systems, and Neural Networks.

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AI 2004 : Advances in artificial intelligence ; 17th Australian Joint conference on artificial intelligence, Cairns, Australia, December 4-6, 2004, proceedings

AI 2004 was the seventeenth in the series of annual Australian artificial intelli-gence conferences. This conference is the major forum for artificial intelligenceresearch in Australia. It has consistently attracted strong international partic-ipation. This year more than two thirds of the submissions were from outsideAustralia.The current volume is based on the proceedings of AI 2004. AI 2004 was collo-cated with Complex 2004, the 7th Asia-Pacific Conference on Complex Systems,with the aim of promoting cross-fertilization and collaboration in areas of com-plex and intelligent systems

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Aging and Senescence

Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. This deterioration is the primary risk factor for major human pathologies, including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases. Aging research has experienced an unprecedented advance over recent years, particularly with the discovery that the rate of aging is controlled, at least to some extent, by genetic pathways and biochemical processes conserved in evolution. Although recent developments in molecular biology are far from understanding the biological basis of aging, research suggests that targeting the aging process itself could ameliorate many age-related pathologies.

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Agents and peer-to-peer computing ; Vol. 3601 ; 3rd international workshop, AP2PC 2004, New York, NY, USA, July 19, 2004, revised and invited papers

This volume presents the fully revised papers presented at the Third International Workshop on Agents and Peer-to-Peer Computing, AP2PC 2004, held in New York City on July 19, 2004 in the context of the Third International Joint Conference on Autonomous Agents and Multi-Agent Systems (AAMAS 2004). The volume is organized in topical sections on P2P networks and search performance, emergent communities and social behaviours, semantic integration, mobile P2P systems, adaptive systems, agent-based resource discovery, as well as trust and reputation.

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Agent Intelligence Through Data Mining

AGENT INTELLIGENCE THROUGH DATA MINING offers a self-contained overview of a relatively young but important area of research: the intersection of agent technology and data mining. This intersection leads to considerable advancements in the area of information technologies, drawing the increasing attention of both research and industrial communities. It can take two forms: a) the more mundane use of intelligent agents for improved data mining and; b) the use of data mining for smarter, more efficient agents. The second approach is the main focus of this volume. this book presents a methodology for developing multi-agent systems, describes available open-source tools to support this process, and demonstrates the application of the methodology on three different cases. AGENT INTELLIGENCE THROUGH DATA MINING is designed for a professional audience composed of researchers and practitioners in industry.

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Agent and Multi-Agent Systems : Technologies and Applications ; 2nd KES International Symposium, KES-AMSTA 2008, Incheon, Korea, March 26-28, 2008. Proceedings

The KES-AMSTA Symposium Series is a sub-series of the KES Conference Series. The aim of the symposium was to provide an international forum for scientific research into the technologies and applications of agent and multi-agent systems.

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