الصفحة 2
الصفحة 2
Funds, Flows and Time : An Alternative Approach to the Microeconomic Analysis of Productive Activities
The subject of this book is production, which is an important and extensive field in economic science. In fact, production, distribution and consump tion were long considered the three federated kingdoms which together formed the great empire of the economy. According to other slightly dif ferent traditions, production also held pride of place, specifically as a basic link in the long chain of social reproduction. Today, whatever the theoreti cal approach, production is a fundamental requirement for human survival. This was not, however, always the case. For much of the history of man kind hominids were hunter, scavenger and gatherers, with very little con trol over their environment, and extremely little in the way of artefacts with which to work. However, since the Neolithic revolution, productive processes have constituted an essential mechanism, providing human soci ety with goods and services to satisfy its needs and cravings.
Functional Neuroanatomy of Pain
Pain is an unpleasant but very important biological signal for danger. Nociception is necessary for survival and maintaining the integrity of the organism in a potentially hostile environment. Pain is both a sensory experience and a perceptual metaphor for damage and it is activated by noxious stimuli that act on a complex pain sensory apparatus. However, chronic pain having no more a protective role can become a ruining disease itself, termed "neuropathic pain".
Functional Hemodynamic Monitoring
Hemodynamic monitoring is one of the major diagnostic tools available in the acute care setting to diagnose cardiovascular insufficiency and monitor changes over time in response to interventions. However, the rationale and efficacy of hemodynamic monitoring to affect outcome has come into question. We now have increasing evidence that outcome from critical illness can be improved by focused resuscitation based on existing hemodynamic monitoring, whereas non-specific aggressive resuscitation impairs survival. Thus, this book frames hemodynamic monitoring into a functional perspective wherein hemodynamic variables and physiology interact to derive performance and physiological reserve estimates that themselves drive treatment. This philosophy, as well as the limitations and applications of common and evolving hemodynamic measures and their focused use in the care of critically ill patients are discussed, relevant to one underlying truth: No monitoring device, no matter how simple or sophisticated, will improve patient-centered outcomes useless coupled to a treatment which, itself, improves outcome.
From industry 4.0 to Quality 4.0 : An innovative TQM guide for sustainable digital age businesses
Describes the development of quality over various stages, from product inspection, through quality control to the present ISO 9000 systems. It also highlights the advantages of the quality management system (QMS) standards and the need for certification by organizations and enterprises/firms interested in taking advantage of the various benefits of these standards to improve their systems and aid their survival in a globally competitive market.
Food safety and toxicology : Present and future perspectives
Safety assurance of consumer goods has become a global challenge. The presence of natural and synthetic contaminants in food compromises food safety and poses a risk to public health. Discusses biological and chemical food contaminants, predictive and detection methods of food toxicants, survival mechanism of food pathogens, legislation on microbial contaminants to prevent public health risks and strategies to mitigate contamination.
Financial Distress, Corporate Restructuring and Firm Survival : An Empirical Analysis of German Panel Data
Philipp Jostarndt analyzes the anatomy of financial distress for a large sample of German corporations. He studies distress-induced changes in ownership and control, success factors in distressed equity infusions, and firms’ choice between in- and out-of-court debt restructurings. Moreover, he conducts a survival analysis to examine the determinants of survival, acquisition, and bankruptcy as alternative paths to exit financial distress. He includes both the firm perspective as well as the market valuations of the undertaken restructurings and, where applicable, relates the findings to the microstructure of Germany’s revised bankruptcy legislation.
Failure rate modelling for reliability and risk
Failure Rate Modelling for Reliability and Risk focuses on reliability theory and, specifically, on the failure rate (the hazard rate, the force of mortality) modelling and its generalizations, on systems operating in a random environment and on repairable systems. The failure rate is one of the crucial probabilistic characteristics for a number of disciplines; including reliability, survival analysis, risk analysis and demography.
Exceptional Lifespans
How long can humans live? This open access book documents, verifies and brings to life the advance of the frontier of human survival. It carefully validates data on supercentenarians, aged 110+, and semi-supercentenarians, aged 105-109, stored in the International Database on Longevity (IDL).
Emergence and Survival of New Businesses : Econometric Analyses
Using Germany as an example, the book gives a comprehensive review on entrepreneurial activity, and draws the general conclusion that new businesses should not be subsidized with a watering can.
EGFR Signaling Networks in Cancer Therapy
EGFR Signaling Networks in Cancer Therapy, is separated into two sections. The first of which probes the molecular pathways and the intersection of signaling networks which are frequently deregulated in human cancers, the second section illustrates the many ways in which EGF receptor contribute to abnormal survival and migration signaling in cancer cells and to epithelial to mesenchymal transition and metastasis.
Eating, Drinking: Surviving : The International Year of Global Understanding - IYGU
This publication addresses the global challenges of food and water security in a rapidly changing and complex world. The essays highlight the links between bio-physical and socio-cultural processes, making connections between local and global scales, and focusing on the everyday practices of eating and drinking, essential for human survival. Written by international experts, each contribution is research-based but accessible to the general public.
Dynamic Regression Models for Survival Data
This book studies and applies modern flexible regression models for survival data with a special focus on extensions of the Cox model and alternative models with the aim of describing time-varying effects of explanatory variables.
Dissecting the Criminal Corpse : Staging Post-Execution Punishment in Early Modern England
Those convicted of homicide were hanged on the public gallows before being dissected under the Murder Act in Georgian England. Yet, from 1752, whether criminals actually died on the hanging tree or in the dissection room remained a medical mystery in early modern society. Dissecting the Criminal Corpse takes issue with the historical cliché of corpses dangling from the hangman’s rope in crime studies. Some convicted murderers did survive execution in early modern England. Establishing medical death in the heart-lungs-brain was a physical enigma. Criminals had large bullnecks, strong willpowers, and hearty survival instincts. Extreme hypothermia often disguised coma in a prisoner hanged in the winter cold. The youngest and fittest were capable of reviving on the dissection table. Many died under the lancet. Capital legislation disguised a complex medical choreography that surgeons staged. They broke the Hippocratic Oath by executing the Dangerous Dead across England from 1752 until 1832.
Digital Peripheries : The Online Circulation of Audiovisual Content from the Small Market Perspective
This is book. Media industry research and EU policymaking are predominantly tailored to large (and, in the latter case, Western) European markets. This open access book addresses the specific qualities of smaller media markets, highlighting their vulnerability to global digital competition and outlining survival strategies for them.
Digital Imaging and Communications in Medicine (DICOM) : A Practical Introduction and Survival Guide
This is the first Digital Imaging and Communications in Medicine (DICOM) book to introduce this complex imaging standard from a very practical point of view. It is aimed at a broad audience of radiologists, clinical administrators, information technologists, and digital medicine practitioners.
Data analytics, computational statistics, and operations research for engineers : Methodologies and applications
Presents applications of computationally intensive methods, inference techniques, and survival analysis models. It discusses how data mining extracts information and how machine learning improves the computational model based on the new information.
Cyclin Dependent Kinase 5 (Cdk5)
Cyclin Dependent Kinase 5 provides a comprehensive and up-to-date collection of reviews on the discovery, signaling mechanisms and functions of Cdk5, as well as the potential implication of Cdk5 in the treatment of neurodegenerative diseases. Since the identification of this unique member of the Cdk family, Cdk5 has emerged as one of the most important signal transduction mediators in the development, maintenance and fine-tuning of neuronal functions and networking. Further studies have revealed that Cdk5 is also associated with the regulation of neuronal survival during development as well as in neurodegenerative diseases. These observations indicate that precise control of Cdk5 is essential for the regulation of neuronal survival. The pivotal role that Cdk5 appears to play in both the regulation of neuronal survival and synaptic functions thus raises the interesting possibility that Cdk5 inhibitors may have therapeutic potential for the treatment of a number of neurodegenerative diseases.
Computational Probability : Algorithms and Applications in the Mathematical Sciences
Computational probability encompasses data structures and algorithms that have emerged over the past decade that allow researchers and students to focus on a new class of stochastic problems. COMPUTATIONAL PROBABILITY is the first book that examines and presents these computational methods in a systematic manner. The techniques described here address problems that require exact probability calculations, many of which have been considered intractable in the past. The first chapter introduces computational probability analysis, followed by a chapter on the Maple computer algebra system. The third chapter begins the description of APPL, the probability modeling language created by the authors. The book ends with three applications-based chapters that emphasize applications in survival analysis and stochastic simulation.
Cold War Civil Defence in Western Europe : Sociotechnical Imaginaries of Survival and Preparedness
This edited collection brings together established and new perspectives on Cold War civil defence in Western Europe within a common analytical framework that also facilitates comparative and transnational dimensions. The current interest in creating disaster-resilient societies demands new histories of civil defence. Historical contextualization is essential in order to understand what is at stake in preparing, devising, and implementing forms of preparedness, protection, and security that are specifically targeted at societies and citizens. Applying the concept of sociotechnical imaginaries to civil defence history, the chapters of this volume cover a range of new themes, from technology and materiality to media, memory, and everyday experience.
Mastering Your PhD : Survival and Success in the Doctoral Years and Beyond
Mastering your PhD" helps guide PhD students through their graduate student days. Filled with practical advice on getting started, communicating with your supervisor, staying the course, and planning for the future, this book is a handy guide for graduate students who need that extra bit of help getting started and making it through. Every year, thousands of students around the world embark on the long and difficult journey toward a PhD. Some of these students will make it through their program with flying colors. Others will experience difficulty getting to the end: some will sink and some will manage to swim – barely. The doctoral years can be daunting. While mainly directed to PhD students in the sciences, the book's scope is broad enough to encompass the obstacles and hurdles that almost all PhD students face at some point in their doctoral training. Who should read this book? Students of the physical and life sciences, computer science, math, and medicine thinking about entering a PhD program, doctoral students at the beginning of their research and any graduate student who is feeling frustrated and stuck. It’s never too early or too late
