الصفحة 2
الصفحة 2
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Nonlinear Analysis and Synthesis Techniques for Aircraft Control

Given the continuous increase in the complexity of aircraft control laws, and the corresponding - crease in the demands on their performance and reliability, industrial control law designers are highly motivated to explore the applicability of new and more powerful methods for design and analysis. The successful application of fully nonlinear control techniques to aircraft control problems o?ers the prospect of improvements in several di?erent areas. Firstly, there is the possibility of - proving design and analysis criteria to more fully re?ect the nonlinear nature of the dynamics of the aircraft. Secondly, the time and e?ort required on the part of designers to meet demanding speci?cations on aircraft performance and h- dling could be reduced. Thirdly, nonlinear analysis techniques could potentially reduce the time and resources required to clear ?ight control laws, and help to bridge the gap between design, analysis and ?nal ?ight clearance.

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New Vision of Metformin in treating cancer

The anti-diabetic drug metformin is rapidly emerging as a potential anticancer agent. Metformin is a biguanide that is effective in treating type 2 diabetes and the insulin resistance syndromes, improves insulin resistance by reducing hepatic gluconeogensis and by enhancing glucose uptake by skeletal muscle. Metformin can reduce the incidence of cancers and can reduce the mortality from cancers, increase the response to treatment cancer cells when using radiotherapy and chemotherapy, reduce the likelihood of relapse. Diabetes can be a factor in the occurrence of various types of cancer, and develop a variety of cancers such as colo-rectal, pancreas and liver cancers, compared to non-diabetic patients. Incidence of various cancers is high among patients of T2DM due to insulin resistance and mitogenic effects caused by hyperglycemia.

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New technical approaches and medications to improve fertility for women in Syria

Egg freezing is one way of preserving a woman's fertility so she can try to have a family in the future. It involves collecting a woman's eggs, freezing them and then thawing them later on so they can be used in fertility treatment. Egg freezing won't lower your ovarian reserve and won't decrease your chances of getting pregnancy naturally in the future. To understand why, we will first of all focus on the ovulation process. During each menstrual cycle—typically each month—one egg makes it through the whole ovulatory process, and we will discuss all the reasons which may suggest to do such a specific process in women such as being in malignant diseases and the risk of its side effects of this therapy on fertility for example this medication or radiation therapy mainly in a abdomen area is reducing fertility beside other types of medications mentioned in this research

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New pharmacological hypothesis for cancer therapy and treatment

Despite the considerable development of new cancer drugs the mortality remains high and the improvement in survival rate remains poor compared to the number of new concepts of cancer therapy in which we will review in our study and we will focus on two possible reasons for that delay in success such as the limitation of diagnostic tools to perform early detection for the tumor in a stage where it can be well treated or even cured as it is often a silent disease in the start phase of it...

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New diagnostic method th detect peritoneal metastases in colorectal cancer

Colorectal cancer is the third common reason of death in population worldwide therefore we will focus in our study about description of this type of cancer and its symptoms to raise the public awareness to go to the right specialist as soon as the symptoms appear to improve early detection of this disease and the overall survival and we will highlight the best diet and life style to avoid this type of cancer hopefully beside that we will present all the most successful therapies of this disease from different classes of compounds such as chemotherapy or anti angiogenic and Metformin and other bacterial therapy however the major goal of the experimental part of this research is performed to establish a new promising diagnostic tool by Near Infra-red camera after injection of indyocine green to detection the peritoneal metastasis of colorectal in 15 patients since this kind of metastasis

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New Concepts of Antiviral Therapy

Antiviral drugs are important tools for treatment or prevention of viral infections. These drugs were first used for monotherapy, but nowadays combinations of antiviral agents are often part of a standard treatment as evidenced by e.g. HAART (highly active antiretroviral therapy). However, in almost every case of antiviral therapy, drug resistant viruses appear. In addition, the low oral bioavailability, toxicity and the number of severe side effects still pose significant problems. All of the latter issues limit the clinical usefulness and drive the need for improved antiviral strategies. These strategies include new drugs and targets, novel modes of action, vector-based treatments and even the block of defined genes by inhibiting mRNA formation (siRNA).

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New challenges in software engineering ; Vol 1

Explores the key challenges shaping the future of software development, including automation, AI-driven development, security-focused engineering, resilient and autonomous architectures, business process optimization, cloud computing, microservices, high-performance distributed systems, and sustainable technologies. Software engineering is undergoing a constant transformation, driven by rapid technological advances and evolving market demands. additionally, it delves into the ethical considerations of AI, the evolution of intuitive user interfaces, and the importance of multidisciplinary collaboration.

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New Business Models for the Reuse of Secondary Resources from WEEEs : The FENIX Project

This book summarizes research being pursued within the FENIX project, funded by the EU community under the H2020 programme, the goal of which is to design a new product service paradigm able to promote innovative business models, to open added value to the vessels and to create new market segments. It experiments and validates its approach on three new concepts of added-value specialized vessels able to run requested services for several maritime sectors in the most effective, efficient, economic valuable and eco-friendly way. The three vessels share the same lean design methodology, IoT tools and HPC simulation strategy: a lean fact-based design model approach, which combines real operative data at sea with lean methodology, to support the development and implementation of the vessel concepts; IT customized tools to enable the acquisition, processing and usage of on board and local weather data, through an IoT platform, to provide business services to different stakeholders; HPC simulation, providing a virtual towing tank environment, for early vessel design improvement and testing. The book demonstrates that an integrated LCC analysis and LCC strategy to guarantee sustainability to vessels concepts and the proper environmental attention inside the maritime industry.

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Neutron Scattering in Biology : Techniques and Applications

The advent of new neutron facilities and the improvement of existing sources and instruments world wide supply the biological community with many new opportunities in the areas of structural biology and biological physics. The present volume offers a clear description of the various neutron-scattering techniques currently being used to answer biologically relevant questions. Their utility is illustrated through examples by some of the leading researchers in the field of neutron scattering. This volume will be a reference for researchers and a step-by-step guide for young scientists entering the field and the advanced graduate student.

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Neuroblastoma

Neuroblastoma is a medical enigma. As a childhood neoplasm arising from neural crest cells, it is characterized by diverse clinical behaviors ranging from spontaneous remission to rapid tumor progression and death. Although clinical outcome can be predicted to a large extent by the stage of disease and the age at diagnosis, an in-depth understanding of its clinico-pathological behavior, now greatly aided by sophisticated molecular genetic profiling, will improve diagnostic precision and refine risk-based therapies. Comprehensive international efforts have advanced our understanding of tumor biology and improved the clinical management of children with neuroblastoma. This book reviews our current understanding of the genes and biological pathways that contribute to neuroblastoma pathogenesis, modern risk-based treatment approaches for these patients, and recent advances in biologically based therapy. It provides a concise up-to-date reference for practitioners, students, and researchers.

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Neural Nets ; 16th Italian Workshop on Neural Nets, WIRN 2005, International workshop on natural and artificial immune systems, NAIS 2005, Vietri sul Mare, Italy, June 8-11, 2005, Revised Selected Papers

This book constitutes the thoroughly refereed postproceedings of the 16th Italian Workshop on Neural Nets, WIRN 2005, as well as the satellite International Workshop on Natural and Artificial Immune Systems, NAIS 2005, held in Vietri sul Mare, Italy in June 2005. The 41 revised papers presented together with a lecture by the winner of the Premio Caianiello award were carefully reviewed and improved during two rounds of selection and refereeing.

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Networking -- ICN 2005 ; Vol. 3420 : 4th International Conference on Networking, Reunion Island, France, April 17-21, 2005, Proceedings, Part I

The International Conference on Networking (ICN 2005) was the fourth conf- ence in its series aimed at stimulating technical exchange in the emerging and important ?eld of networking. On behalf of the International Advisory C- mittee, it is our great pleasure to welcome you to the proceedings of the 2005 event. Networking faces dramatic changes due to the customer-centric view, the venue of the next generation networks paradigm, the push from ubiquitous n- working, and the new service models. Despite legacy problems, which researchers and industry are still discovering and improving the state of the art, the ho- zon has revealed new challenges that some of the authors tackled through their submissions. In fact ICN 2005 was very well perceived by the international networking community. A total of 651 papers from more than 60 countries were submitted, from which 238 were accepted. Each paper was reviewed by several members of the Technical Program Committee. This year, the Advisory Committee revalidated various accepted papers after the reviews had been incorporated. We perceived a signi?cant improvement in the number of submissions and the quality of the submissions. The ICN 2005 program covered a variety of research topics that are of current interest, starting with Gridnetworks, multicasting, TCP optimizations, QoS and security, emergency services, and network resiliency. The Program Committee selected also three tutorials and invited speakers that addressed the latest - search results from the international industries and academia, and reports on ?ndings from mobile, satellite, and personal communications related to 3rd- and 4th-generation research projects and standardization.

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Neonatal Cranial Ultrasonography

It provides important information on brain maturation in the (preterm) neonate and enables the detection of frequently occurring brain anomalies in both preterm and full term neonates. Furthermore, it can be repeated as often as is necessary. In this edition of Neonatal Cranial Ultrasonography, the focus is on the basics of the technique, from patient preparation through to screening strategies and the classification of abnormalities. Many new ultrasound images have been included to reflect the improvements in image quality since the first edition. Essential information is provided about both the procedure itself and the normal ultrasound anatomy. Standard technique using the anterior fontanelle as the acoustic window is described and illustrated, but emphasis is also placed on the value of supplementary acoustic windows.

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Negotiations with Asymmetrical Distribution of Power : Conclusions from Dispute Resolution in Network Industries

In many ways, complex negotiations shape the business arena of regulated network markets. In general, negotiating partners are not equal with regard to their various sources and instruments of power. This book unfolds a differentiated and, at the same time, applicable framework for analyzing and managing negotiations. It creatively combines power and negotiations theories. In addition, it illustrates the findings in a very inspiring way by investigating negotiation episodes in network industries such as telecommunications and railways. Thus, this book is highly relevant for all those wanting to better understand the complex political processes and outcomes in regulated industries, but also for those bearing practical responsibility in regulatory and government affairs and wanting to improve their management performance.

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Natural Language Processing – IJCNLP 2004 ; 1st International Joint Conference, Hainan Island, China, March 22-24, 2004, Revised Selected Papers

This book constitutes the thoroughly refereed post-proceedings of the First International Joint Conference on Natural Language Processing, IJCNLP 2004, held in Hainan Island, China in March 2004. The 84 revised full papers presented in this volume were carefully selected during two rounds of reviewing and improvement from 211 papers submitted. The papers are organized in topical sections on dialogue and discourse; FSA and parsing algorithms; information extractions and question answering; information retrieval; lexical semantics, ontologies, and linguistic resources; machine translation and multilinguality; NLP software and applications, semantic disambiguities; statistical models and machine learning; taggers, chunkers, and shallow parsers; text and sentence generation; text mining; theories and formalisms for morphology, syntax, and semantics; word segmentation; NLP in mobile information retrieval and user interfaces; and text mining in bioinformatics.

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Nanotechnology for Smart Concrete

Nanomaterials can markedly improve the mechanical properties of concrete, as well as reduce the porosity and enhance the durability of concrete. The application of nanotechnology in concrete is still in its infancy. However, an ever-growing demand for ultra-high-performance concrete and recurring environmental pollution caused by ordinary Portland cement has encouraged engineers to exploit nanotechnology in the construction industry. Nanotechnology for Smart Concrete discusses the advantages and applications of nanomaterials in the concrete industry, including high-strength performance, microstructural improvement, self-healing, energy storage, and coatings. The book: Analyses the linkage of concrete materials with nanomaterials and nanostructures / Discusses the applications of nanomaterials in the concrete industry, including energy storage in green buildings, anti-corrosive coatings, and inhibiting pathogens and viruses / Covers self-healing concrete / Explores safety considerations, sustainability, and environmental impact of nanoconcrete / Includes an appendix of solved questions

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Nanotechnology and drug delivery : Principles and applications

Presents an overview of the rapidly developing field of nanotechnology applications in drug delivery systems and covers a variety of technologies and materials that help in achieving vast variation in the particle size needed in technology and drug delivery-based research. It discusses nanotechnology’s use in healthcare for the development of target-specific drug therapy and smart field systems and in the pharmaceutical industry to improve the quality, efficacy, and shelf life of medicines. Bringing together principles, theory, practice, and applications of nanotechnology.

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Nanotechnologies, Hazards and Resource Efficiency : A Three-Tiered Approach to Assessing the Implications of Nanotechnology and Influencing its Development

Nanotechnology is frequently described as an enabling technology and 1 fundamental innovation, i.e. it is expected to lead to numerous innovative developments in the most diverse fields of technology and areas of app- cation in society and the marketplace. The technology, it is believed, has the potential for far-reaching changes that will eventually affect all areas of life. Such changes will doubtlessly have strong repercussions for society and the environment and bring with them not only the desired and intended effects such as innovations in the form of improvements to products, pr- esses and materials; economic growth; new jobs for skilled workers; relief for the environment; and further steps toward sustainable business, but also unexpected and undesirable side effects and consequences.

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Nanopharmaceuticals ; Vol.1 : Expectations and realities of multifunctional drug delivery systems

Reviews advances in the drug delivery field via nanovehicles or nanocarriers that offer benefits like targeted therapy and serves as a single dose magic bullet for multiple drug delivery with improved drug efficiency at a lower dose, transportation of the drug across physiological barriers as well as reduced drug-related toxicity. The chapters are written by a diverse group of international researchers from industry and academia. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems.

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Nanometer technology designs high-quality delay tests

Nanometer Technology Designs: High-Quality Delay Tests discusses these challenges in detail and proposes new techniques and methodologies to improve the overall quality of the delay test for nanotechnology designs

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