الصفحة 2
الصفحة 2
Molecular Neurosurgery with Targeted Toxins
Focuses on the highly successful use of the immunotoxins, 192 IgG-saporin and ME20.4-saporin, to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals. Also discussed are the uses of anti-DBH-saporin immunotoxin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin that can produce narcoleptic animals, and other saporin conjugates, such as neuropeptide-saporin conjugates for pain research and cholera toxin B chain-saporin to produce a model of central nervous system demyelination. Overview perspectives and, in some cases, more practical details are provided that allow the reader to appreciate exactly what is involved in using these agents. Both practical and theoretical, Molecular Neurosurgery With Targeted Toxins provides readers with not only the background to understand these techniques, but also numerous real-life examples that can be readily adapted to new purposes and an ever-increasing number of new targeted toxins.
Modern parallel programming with C++ and assembly language : X86 SIMD development using AVX, AVX2, and AVX-512
Understand the essential details about x86 SIMD architectures and instruction sets including AVX, AVX2, and AVX-512. / Master x86 SIMD data types, arithmetic instructions, and data management operations using both integer and floating-point operands. / Code performance-enhancing functions and algorithms that fully exploit the SIMD capabilities of a modern x86 processor. Employ C++ intrinsic functions and x86-64 assembly language code to carry out arithmetic calculations using common programming constructs including arrays, matrices, and user-defined data structures. Harness the x86 SIMD instruction sets to significantly accelerate the performance of computationally intense algorithms in applications such as machine learning, image processing, computer graphics, statistics, and matrix arithmetic. / Apply leading-edge coding strategies and techniques to optimally exploit the x86 SIMD instruction sets for maximum possible performance.
Modern natural product synthesis
Describes the details of the synthesis routes including unexpected reactions and syntheses. By presenting detailed stories behind the total synthesis developments, including those routes that were unsuccessful the book provides the reader with a better understanding of how other researchers devise their strategy and overcome difficulties in their studies. The contributions in the book have focused on highlighting the research from Japan however it is appealing to researchers and students worldwide. This compilation of cutting-edge natural product synthesis provides high-quality expertise, especially to graduate students and young researchers, regarding research on synthetic organic chemistry. It can be utilized as teaching material in university seminars as well as provide guidance to researchers in the area of total synthesis.
Modern Construction Handbook
Tried and tested component details, examples focusing on sustainability and energy consumption, and an update on finite element analysis (FEA) and computational fluid dynamics (CFD) introduced in the last edition set new standards for this handbook which serves as a foundational textbook in many architecture courses
Modern construction envelopes
Using current examples by renowned architects, Watts presents the constructive and material-related details. It is based on a text, photos, and standardized detail drawings, as well as 3D representations of the components
Modelling of Powder Die Compaction
In particular, the book presents a number of case studies that have been developed to test compaction models. Full details of the data required for input to compaction models of these case studies is given, together with a survey of the techniques used to generate the data. Details are also given of methods to produce and assess components for validation of die compaction models. The inclusion of information on case studies then provides a reference for the testing and validation of compaction models.
Modeling biological systems : Principles and applications
This extensively revised second edition of Modeling Biological Systems: Principles and Applications describes the essentials of creating and analyzing mathematical and computer simulation models for advanced undergraduates and graduate students. It offers a comprehensive understanding of the underlying principle, as well as details and equations applicable to a wide variety of biological systems and disciplines. Students will acquire from this text the tools necessary to produce their own models. The text contains two major sections: Principles and Applications. The first section discusses the principles of biological systems with a thorough description of the essential modeling activities of formulation, implementation, validation, and analysis. These activities are illustrated by a set of example models taken from recent and classical literature, chosen for their breadth of coverage and current timeliness. The new edition updates extensively many of these topics, especially quantitative model formulation, validation and model discrimination using information theory measures and Bayesian probability, and stability analysis and non-dimensionalization.
Micro-Tomographic Atlas of the Mouse Skeleton
Micro-Tomographic Atlas of the Mouse Skeleton serves as an essential guide containing unique systematic description of all calcified components of the mouse. This detailed atlas fulfils an emerging need for high resolution anatomical details as mice become a standard laboratory animal in skeletal research and the use of m CT technology is rapidly increasing as a key analytical tool in the study of bone.
Microformats : Empowering Your Markup for Web 2.0
This book is a comprehensive guide to microformats. It explores why—in Bill Gates' words—"We need microformats," how microformats work, and the kinds of problems microformats help solve. The book covers every current microformat, with complete details of the syntax, semantics, and uses of each, along with real-world examples and a comprehensive survey of the tools available for working with them. the book also features case studies detailing how major web content publishers such as yahoo put microformats to work in their web applications.
Microcontrollers in Practice
Stressing common characteristics and real applications of the most used microcontrollers, this practical guide provides readers with hands-on knowledge of how to implement three families of microcontrollers (HC11, AVR, and 8051). Unlike the rest of the ocean of literature on individual chips, Microcontrollers in Practice supplieS side-by-side comparisons and an overview that treats the systems as resources available for implementation. Packed with hundred of practical examples and exercises to foster mastery of concepts and details, the guide also includes several extended projects. By treating the less expensive 8-bit and RISC microcontrollers, this information-dense manual equips students and home-experimenters with the know-how to put these devices into operation.
Metric Handbook : Planning and Design Data
A major handbook of planning and design data for architects and architecture students. Covering basic design data for all the major building types, it is the ideal starting point for any project. For each building type, the book gives the basic design requirements and all the principal dimensional data, and succinct guidance on how to use the information and what regulations the designer needs to be aware of.
Methods of Celestial Mechanics: Vol. I: Physical, Mathematical, and Numerical Principles
G. Beutler's Methods of Celestial Mechanics is a coherent textbook for students in physics, mathematics and engineering as well as an excellent reference for practitioners. This Volume I gives a thorough treatment of celestial mechanics and presents all the necessary mathematical details that a professional would need. After a brief review of the history of celestial mechanics, the equations of motion (Newtonian and relativistic versions) are developed for planetary systems (N-body-problem), for artificial Earth satellites, and for extended bodies (which includes the problem of Earth and lunar rotation). Perturbation theory is outlined in an elementary way from generally known mathematical principles without making use of the advanced tools of analytical mechanics. The variational equations associated with orbital motion - of fundamental importance for parameter estimation (e.g., orbit determination), numerical error propagation, and stability considerations - are introduced and their properties discussed in considerable detail. Numerical methods, especially for orbit determination and orbit improvement, are discussed in considerable depth. The algorithms may be easily applied to objects of the planetary system and to Earth satellites and space debris.
Men’s care center
"سين" مركزٌ للعافية والاسترخاء، مصمم بمزيج فريد من العناصر الطبيعية والهندسة المعمارية الحديثة ليمنح الزوار تجربة حسية متكاملة. يدمج المشروع المساحات الخضراء الداخلية والإضاءة الهادئة وخطوط التصميم المعاصرة لخلق بيئة فاخرة وهادئة. تشمل المساحات الرئيسية الحديقة الداخلية، والحمام التركي التقليدي، وغرف كبار الشخصيات، ومنطقة الاستقبال - جميعها مُرتبة بعناية لتعزيز الهدوء والتوازن. يركز التصميم على التفاصيل المعمارية والوظيفية، موفرًا للضيوف ملاذًا من ضغوط الحياة اليومية. خضعت التصاميم الداخلية والخارجية لدراسة دقيقة لضمان تجربة راقية وشاملة. “Sén” is a wellness and re laxation center designed with a unique blend of natural elements and modern architecture to provide visitors with a complete sensor experience. The project integrates indoor greenery, calming lighting, and con temporary design lines to create a luxurious and peaceful environment. Key spaces include the indoor garden, traditional hammam, VI P rooms, and reception area — all carefully arranged to promote tranquility and balance. The design focuses on architectural and functional details, offering guests a retreat from the stresses of everyday life. Both interior and exterior designs were carefully studied to ensure a refined and holistic experience.
Memory B-cells : Methods and protocols
Details in methods to assess memory B cell formation and function in mice and humans. Chapters guide readers through tetramer-based methods to assess antigen-specific memory B cell dynamics in humans and mice in different vaccine, next-generation deep-sequencing, single-cell techniques to assess epigenomic, VDJ landscapes, lymph node aspirates from humans, advanced imaging, murine models to determine memory B cells formation, and bioinformatic techniques and in silico modelling of memory b cell formation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Mediterranean Island Landscapes : Natural and Cultural Approaches
Mediterranean islands exhibit many similarities in their biotic ecological, physical and environmental characteristics. There are also many differences in terms of their human colonization and current anthropogenic pressures. This book addresses in three sections these characteristics and examines the major environmental changes that the islands experienced during the Quaternary period. The first section provides details on natural and cultural factors which have shaped island landscapes. It describes the environmental and cultural changes of the Holocene and their effects on biota, as well as on the current human pressures that are now threats to the sustainability of the island communities. The second section focuses on the landscapes of the largest islands namely Sicily, Sardinia, Corsica, Cyprus, Crete, Malta and the Balearics. Each island chapter includes a special topic reflecting a particular characteristic of the island. Part three presents strategies for action towards sustainability in Mediterranean islands and concludes with a comparison between the largest islands.
Medicinal Plants for Holistic Health and Well-Being
Medicinal Plants for Holistic Health and Well-Being discusses, in depth, the use of South African plants to treat a variety of ailments, including tuberculosis, cancer, periodontal diseases, acne, postmacular hypomelanosis, and more. Plants were selected on the basis of their traditional use, and the book details the scientific evidence that supports their pharmacological and therapeutic potential to safely and effectively treat each disease. Thus, this book is a valuable resource for all researchers, students and professors involved in advancing global medicinal plant research
Medical laboratory technology procedure : manual for routine diagnostic tests ; Vol.3
Salient features Predominantly tailored to the requirements of laboratories with limited facilities in developing countries, this manual: Introduces methods and procedures for producing reliable laboratory findings Describes all tests in a step-by-step manner with guidelines to avoid errors and hazards Explains care and use of laboratory equipment and preparation of reagents Details Zika and Chikungunya virus infections Highlights the clinical significance of laboratory findings Provides illustrations for easy comprehension The fourth edition features a number of important additions containing the latest topics relevant to the subject
Medical Emergencies in the Dental Office
Prepares dental professionals to promptly and proactively recognize and manage medical emergencies that may occur in the dental office. It details how to anticipate potential emergencies and what resources must be on hand to deal effectively with these situations. The book is arranged in eight sections concentrating on topics such as prevention of emergencies through patient evaluation (medical history) and specific types of more common emergencies that practitioners may encounter. "It successfully fulfils its aim of stimulating all members of the dental team to improve and maintain their skills in the effective prevention, recognition and management of medical emergencies.
MCITP self-paced training Kit (Exam 70-444) : Optimizing and maintaining a database administration solution microsoft SQL server 2005
Designed to help you make the most of your study time. Maximize your performance on the exam by learning to: * Monitor and troubleshoot queries, databases, and servers * Help defend against injection attacks, denial of service attacks, worms, and viruses * Manage security strategies and perform audits * Detect and resolve data conflicts * Diagnose faults and recover from database failures and disasters * Optimize database availability with failover clustering, database mirroring, log shipping, and replication * Customize a maintenance strategy and automate routine tasks * Build, debug, and deploy SQL Server Integration Services packages PRACTICE TESTS Assess your skills with practice tests on CD. You can work through hundreds of questions using multiple testing modes to meet your specific learning needs. You get detailed explanations for right and wrong answers-including a customized learning path that describes how and where to focus your studies. Your training kit includes: Details inside. * Official self-paced study guide. * Practice tests with multiple, customizable testing options and a learning plan based on your results. *400+ practice and review questions. * Case scenarios, practice exercises, and best practices. *180-day evaluation version of Microsoft SQL Server 2005 Enterprise Edition. * Fully searchable eBook of this guide.
Mathematics - Key Technology for the Future : Joint Projects Between Universities and Industry 2004–2007
This book is about the results of a number of projects funded by the BMBF in the initiative "Mathematics for Innovations in Industry and Services". It shows that a broad spectrum of analytical and numerical mathematical methods and programming techniques are used to solve a lot of different specific industrial or services problems. The main focus is on the fact that the mathematics used is not usually standard mathematics or black box mathematics but is specifically developed for specific industrial or services problems. Mathematics is more than a tool box or an ancilarry science for other scientific disciplines or users. Through this book the reader will gain insight into the details of mathematical modeling and numerical simulation for a lot of industrial applications.
