الصفحة 2
الصفحة 2
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Raisins extracts gel : effect in buccal cavity

In this study, Antibacterial and other compounds of raisin's extract was evaluated. Different methods were utilized to extract the compounds from raisins. The Antibacterial activity of the methanolic extract was evaluated against the bacterial pathogens Staphylococcus aureus, Streptococcus mutans, Escherichia coli, Klebsiella using both disk diffusion and minimum inhibitory concentration (MIC) methods. The methanolic extract exhibited the highest activity against Staphylococcus aureus...

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Railway Development : Impacts on Urban Dynamics

This book addresses the role of railways in urban development. The central aim is to inquire into how especially the development of high-speed rail and light rail links will affect European cities. The analyses are carried out with special attention given to the broader institutional environment of the railway system, including the shift toward privatised railway companies, internationalisation, the occurrence of market and government failures in land markets, and private-public partnerships in the development of railway station areas. The essence of the plans to invest in railway stations is that railway stations are not considered merely as nodes where people transfer from one vehicle to another, but also as places where spatial concentrations of high value activity are recognised as having a positive impact on cities.

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Problems of High Altitude Medicine and Biology

The major characteristic pathological findings of pulmonary vascular remodelling are increased wall thickening of pulmonary vessels and mus- larization of small arteries. In laboratory animals, decreased ambient oxygen concentrations cause similar pathological findings, including pulmonary smooth muscle hypertrophy and proliferation [22,23]. It has been suggested that proliferation of pulmonary arterial smooth muscle cells (PASMC) is a key component of pulmonary vascular remodelling, and several in vitro studies have also addressed that exposure to hypoxia can stimulate prolife- tion of PASMC [13,4,1]. The proliferation of the PASMC begins when the cells enter into the cell cycle.

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Practical Guide to Diagnosing Structural Movement in Buildings

First principles, including crack patterns and cracks, rotational movement, weak routes, load distribution, and movement and orientation ; Expansion cracking, cavity wall tie corrosion, roof spread, springing from deflected beams, and overloaded floors and beams ; Clay heave, uneven loading, eccentric loading on foundations, drains and drain trenches, differential foundation movement, and load concentrations on foundations ; Repair methods, including stitching in brickwork, reinforcing brick mortar joints, tie bars, restraint straps, underpinning, grouting, and root barriers

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Platelet-Rich Plasma (PRP): Therapy and Applications

Platelet-Rich Plasma (PRP) is a portion of the plasma fraction of autologous blood with a platelet concentration above the baseline with the full complement of growth factors and other plasma proteins, the purpose of this research is to evaluate and summarize literature, with particular focus on rejuvenation process, these include regeneration of soft tissue, skin aging mechanisms, as well as wound healing and a study reported in burns. Emerging autologous cellular therapies that utilize platelet-rich plasma (PRP) applications have the potential to play adjunctive roles in a variety of regenerative medicine treatment plans. There is a global unmet need for tissue repair strategies to treat musculoskeletal, osteoarthritis (OA), and patients with chronic complex and recalcitrant wounds.

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Plant Responses to Air Pollution and Global Change

The main force behind climate change is the elevated concentration of CO2 in the at­ mosphere. Carbon dioxide and air pollutants come mostly from the same industrial sources and diffuse globally, so that air pollution is also part of global change in the pre­ sent era. The impacts on plants and plant ecosystems have complex interrelationships and lead to global change in a circular manner as changes in land cover and atmospheric and soil environments. Plant metabolism of CO2 and air pollutants and their gas fluxes in plant ecosystems influence the global gaseous cycles as well as the impacts on plants.The aim of the symposium series is to bring together scien­ tists of various disciplines who are actively involved in research on responses of plant metabolism to air pollution and global change.

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Plant Breeding and Agrarian Research in Kaiserwilhelm-Institutes 1933-1945 : Calories, Caoutchouc, Careers

Offers a history of the agricultural sciences in Nazi Germany. It analyzes scientific practice under the Nazi regime, Nazi agricultural policy and autarkic strategies as well as expansion policy in Eastern Europe. It also offers new insights into the Auschwitz concentration camp. It outlines the Nazi’s comprehensive nutritional and agricultural research program intended to prepare Germany for war by raising productivity through scientific means, researching the relation between nutrition and performance at the edge of starvation, and restructuring the agricultural economy of the continent. The book reveals the relation between science and power in Nazi Germany beyond the usual dichotomy that paints scientists in Nazi Germany either as victims of oppression or as sadistic beasts.

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Periphery and Small Ones Matter : Interplay of Policy and Social Capital

This book analyzes the dualism and inequality insofar as how it is manifested in interregional disparity and small enterprises. Using the case of Indonesia, the author considers how the general direction of policy should be to mitigate the effects of agglomeration forces leading towards concentration, and exploit the same forces by encouraging small businesses to operate in a cluster for collective action. The book addresses these issues by focusing on the role of interactions between policies and institutions, of which social capital is an important part.

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Organic Solid State Reactions

Organic reactions in the absence of solvent, so called “Organic Solid-State Reactions”, have been well established as proceeding much more efficiently and faster than solution reactions in many cases, since solid-state reactions are infinitely high-concentration reactions. Organic solid-state reactions proceed even more selectively than solution reactions in some cases, since substrate molecules in solids or crystals are ordered regularly. Solid-state reactions are important not only for their high efficiency and selectivity but also for their simplicity and cleanness. In this volume, thermochemical and photochemical reactions in the solid state which have been studied mainly during the last five years by eight research groups are included. The editor hopes that this volume will contribute to the further development of organic solid-state reactions and solid-state chemistry.

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Noise-Induced Phenomena in Slow-Fast Dynamical Systems : A Sample-Paths Approach

Stochastic differential equations play an increasingly important role in modeling the dynamics of a large variety of systems in the natural sciences, and in technological applications. This book presents a new constructive approach to the quantitative description of solutions to systems of stochastic differential equations evolving on well-separated timescales. The method, which combines techniques from stochastic analysis and singular perturbation theory, allows the domains of concentration for typical sample paths to be determined, and provides precise estimates on the transition probabilities between these domains. In addition to the detailed presentation of the set-up and mathematical results, applications to problems in physics, biology, and climatology are discussed. The emphasis lies on noise-induced phenomena such as stochastic resonance, hysteresis, excitability, and the reduction of bifurcation delay.

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Natural Fullerenes and Related Structures of Elemental Carbon

This book provides an up-to-date summary of the state of knowledge on natural fullerenes occurrences and the laboratory techniques used to determine their presence at low concentration in rock samples. It demonstrates that natural fullerenes exist and should be searched for in places not yet considered such as carbon-containing deep-seated crustal rocks.Natural Fullerenes and Related Structures of Elemental Carbon is written for professional astronomers, meteoriticists, earth and planetary scientists, biologists and chemists interested in carbon and hydrocarbon vapor condensation. It is an invaluable resource for practicing research scientists and science teachers in Earth and Planetary Science, Astronomy and Carbon Science.

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Mycotoxins in Foodstuffs

Due to the serious spoilage and health issues the presence of mycotoxins can cause, it’s imperative that the food industry has a basic understanding fungi and their corresponding mycotoxins. An indispensable resource, Mycotoxins in Foodstuffs gives an in depth overview by listing the degree of contamination, concentration and country of origin/detection for each case of mycotoxin contamination for each commodity. In addition, the book shows whether or not food is predisposed for mycotoxin contamination.

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Monetary Policy and Macroeconomic Stabilization in Latin America

Latin America is a very important region of the globe, which has been buffeted by successive waves of economic instability within the last decades. These waves have caused several episodes of hyperinflation or near hyperinflation, and several currency and financial crises, which, in certain moments, have even spilled over and affected other emerging markets. This has resulted in huge costs in terms of lost potential growth, and, as is inevitable, the markets most affected by this have been the least capable of defending themselves. In a region plagued by still considerable rates of social exclusion, with some of the highest rates of income concentration in the whole globe, the human costs of these crises have been very substantial. Starting in the early 1990s, the slow implementation of reforms, plus the resumption of more sustained growth—to a substantial degree linked to the increase in commodity prices, especially since the early 2000s—seems to have resulted in a more stable situation. Initially, in early reformers like Chile, later in the larger economies of the region, like Brazil and Mexico, a consensus— embraced by both sides of the political spectrum—towards integration in global markets, both in their trade and financial components, floating exchange rates, independent monetary authorities, and sustainable fiscal policies has emerged.

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Molecular microbiology of heavy metals

Molecular Microbiology of Heavy Metals includes chapters on allocation of metals in cells, metal transporter, storage and metalloregulatory proteins, cellular responses to metal ion stress, transcription of genes involved in metal ion homeostasis, uptake of essential metals, metal efflux and other detoxification mechanisms. Also discussed are metal bioreporters for the nanomolar range of concentration and tools to address the metallome. Chapters in the second part cover specific metals such as Fe, Mn, Cu, Ni, Co, Zn and Mo as key nutrient elements and Ag, As, Cd, Hg and Cr as toxic elements.

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Molecular Biology of the Parathyroid

Caintaining extracellular calcium concentrations within a narrow range is critical for the survival of most vertebrates. PTH, together with vitamin D, responds to hypocalcemia to increase extracellu­ M lar calcium levels, by acting on bone, kidney and intestine. The recent intro­ duction of PTH as a major therapeutic agent in osteoporosis has directed renewed interest in this important hormone and in the physiology of the parathyroid gland. The parathyroid is unique in that low serum calcium stimulates PTH secretion. As hypocalcemia persists, there is also an increase in PTH synthesis. Chronic hypocalcemia leads to hypertrophy and hyper­ plasia of the parathyroid gland together with increased production of the hormone. Phosphate is also a key modulator of PTH secretion, gene expres­ sion and parathyroid cell proliferation. Understanding the biology of the parathyroid as well as the mecha­ nisms of associated diseases has taken great strides in recent years. This book summarizes the molecular mechanisms involved in the function of the para­ thyroid gland. The first chapter reviews the development of the parathyroid gland and the genes involved in this process as identified using genetically manipulated mice. Then the biosynthetic pathway of PTH from gene ex­ pression to its intracellular processing and the sequences in the gene control­ ling its transcription as well as those regulating mRNA processing, stability and translation are described.

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Molecular Biology of Metal Homeostasis and Detoxification : From Microbes to Man

One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits. This book brings together current knowledge of the molecular basis of metal homeostasis and detoxification in various eukaryotic model systems, including yeasts, plants, and mammals. It focuses on the cellular systems controlling metal transport, intracellular distribution, and immobilization as well as on systems regulating metal-dependent transcription. In addition to environmental aspects (including phytoremediation), the book treats the pathophysiology of metal deficiency and overload in relation to disease.

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Methods in Nonlinear Analysis

Nonlinear analysis has developed rapidly in the last three decades. Theories, techniques and results in many different branches of mathematics have been combined in solving nonlinear problems. This book collects and reorganizes up-to-date materials scattered throughout the literature from the methodology point of view, and presents them in a systematic way. It contains the basic theories and methods with many interesting problems in partial and ordinary differential equations, differential geometry and mathematical physics as applications.There are five chapters that cover linearization, fixed-point theorems based on compactness and convexity, topological degree theory, minimization and topological variational methods. Each chapter combines abstract, classical and applied analysis. Particular topics included are bifurcation, perturbation, gluing technique, transversality, Nash–Moser technique, Ky Fan's inequality and Nash equilibrium in game theory, set­valued mappings and differential equations with discontinuous nonlinear terms, multiple solutions in partial differential equations, direct method, quasi­convexity and relaxation, Young measure, compensation compactness method and Hardy space, concentration compactness and best constants, Ekeland variational principle, infinite-dimensional Morse theory, minimax method, index theory with group action, and Conley index theory.

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Medical data processing and analysis

Medical data can be defined as obtaining information from patients (such as signals, images, sounds, chemical components and their concentration, body temperature, respiratory rate, blood pressure, and different treatment measurements) to quantify the patient’s status and disease stage. Computer-aided diagnostic (CAD) systems use classical image processing, computer vision, machine learning, and deep learning methods for image analysis. Using image classification or segmentation algorithms, they find a region of interest (ROI) pointing to a specific location within the given image or an outcome of interest in the form of a label pointing to a diagnosis or prognosis. Computer science, with the evolution of artificial intelligence and machine learning techniques, facilitates the modeling and interpretation of results—from carrying out measurements to experiments and observations.

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Improving Healthcare : A Dose of Competition

Improving Healthcare: A Dose of Competition systematically examines the American health care system from a competition-oriented perspective. The volume surveys the performance of each major sector of the health care system, and identifies impediments to more effective competition. Improving Healthcare examines such issues as competition v. regulation, public and private sector approaches to health care financing, cross-subsidies, licensure, provider market concentration, financial and clinical integration, payment for performance, quality, pharmacy benefit managers, direct-to-consumer advertising of pharmaceuticals, certificates of need, mandates, unionization, the significance of organizational status (nonprofit v. for-profit), and the role of antitrust and consumer protection in health care. It offers concrete recommendations to improve the quality and cost-effectiveness of the American health care marketplace.

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Hormones and the brain

Peripheral hormones have a major impact on the brain: they are able to interfere with its development, to affect release of neurotransmitters and concentrations of receptors, to trigger growth factors involved in lesion repair. These multiple actions account for their capacity to modulate a number of physiological parameters, from reproductive functions to memory, behaviour and aging. Depending upon intensity and duration of exposure, they can be either neuroprotective or neurotoxic, for instance by affecting production of free radicals. This book, based on contributions of pioneer investigators in the field, outlines the ambiguous actions of gonadal steroids (estradiol, progesterone, testosterone, inhibin and activin) and of neurosteroids, related moieties produced in the brain itself. After summarizing their multiple mechanisms of action, which involve both direct effects on neuronal membranes and activation of genes coding for specific proteins in neurons or glial cells, the book outlines the role of hormones in pathogenic processes such as mental disturbances or neurodegenerative diseases.

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