الصفحة 2
الصفحة 2
Mémento de la recherche biomédicale portant sur un médicament à usage humain = Summary of biomedical research on a medicinal product for human use
Presents the reference texts, structures and authorities that govern clinical research in France, as well as its practical aspects. It is aimed at all of its stakeholders, both caregivers and patients. It will allow the most novices to familiarize themselves with the specific vocabulary of this discipline, to answer the questions raised during the conduct or participation in a therapeutic trial, and the most experienced to consider setting up a research structure. clinic in the rules of art.
Mécanique céleste et contrôle des véhicules spatiaux = Celestial mechanics and spacecraft control
The textbook contains two parts: Part 1 is an introduction to celestial mechanics, and part II is devoted to the control of cosmic vehicles motion.The book is written in a clear mathematical style-Definition-Proposition-Lemma-Theorem-Corollary-and is almost self contained.
Max-Plus Linear Stochastic Systems and Perturbation Analysis
This book provides a thorough treatment of the theory of stochastic max-plus linear systems. Max-plus algebra is an algebraic approach to discrete event systems (DES), like queuing networks that are prone to synchronization. Perturbation analysis studies the sensitivity of the performance of DES with respect to changes in a particular system parameter.
Ion Channels
Ion channels play a vital role in basic physiological functions such as generation of electrical activity in nerves and muscle, control of cardiac excitability, intracellular signaling, hormone secretion, cell proliferation and many other biological processes. Because of their prevalence and the critical role they play in virtually all tissue types and organs, ion channels are also involved in a number of pathophysiological conditions. The aim of this volume is to review recent advances in the field of ion channel related diseases. Following an overview chapter summarizing the current state of ion channel screening technologies, five topics covering areas such as cancer, cardiac arrhythmias, cystic fibrosis, and pain have been selected, and the current state of knowledge is presented by leading experts in their field.
Introduction to Computational Biology : An Evolutionary Approach
Molecular biology has changed dramatically over the past two decades. Until the early 1990s genes were studied one at a time by small teams of researchers; today entire genomes are sequenced by internationally collaborating laboratories. In the bygone gene-centered era the accumulation of data was the rate-limiting step in research. Now that step is often data interpretation. This is increasingly dependent on computational methods and as a consequence, computational biology has emerged in the past decade as a new subdiscipline of biology. This introduction to computational biology is centered on the analysis of molecular sequence data. There are two closely connected aspects to biological sequences: (i) their relative position in the space of all other sequences, and (ii) their movement through this sequence space in evolutionary time. Accordingly, the first part of the book deals with classical methods of sequence analysis: pairwise alignment, exact string matching, multiple alignment, and hidden Markov models. In the second part evolutionary time takes center stage and phylogenetic reconstruction, the analysis of sequence variation, and the dynamics of genes in populations are explained in detail. In addition, the book contains a computer program with a graphical user interface that allows the reader to experiment with a number of key concepts developed by the authors.
Introduction à la résolution des systèmes polynomiaux = Introduction to solving polynomial systems
This book is an introduction to algebraic methods for solving this type of equations. We show how the geometry of algebraic varieties defined by these equations, their dimension, their degree, or their components can be deduced from the properties of the corresponding quotient algebras. For this, we approach methods of effective algebraic geometry, such as Grobner bases, resolution by eigenvalues and vectors, resultants, bezoutians, duality, Gorenstein algebras and algebraic residues.
Interventional Radiology in Pain Treatment
Disease whether it is acute, chronic, or at end stage, is all too regularly accompanied by pain. Pain is often difficult to control, in malignant disease in particular, even by using appropriate medications. Anesthesiologists and pain therapists have developed new invasive therapies including nerve block, sympatholysis, and neurolysis useful for both diagnosis and pain management. To insure the efficiency and safety of these procedures, and furthermore for elaborate techniques such as vertebroplasty, cementoplasty, and radio frequency bone ablation, imaging guidance becomes mandatory. This state-of-the-art book describes the techniques elaborated by interventional radiologists in the treatment and palliation of a variety of benign and malignant painful conditions.
Internationalisation of European ICT Activities : Dynamics of Information and Communications Technology
The internationalisation of information and communication technologies has accelerated since the 1990s in Europe and worldwide. Taking a close look at the empirical analysis of competitive trade positions, trends in foreign direct investment and the internationalisation of research and development in ICT brings many new insights about the expansion, innovation and adjustment in the EU’s most dynamic sector. Moreover, the analysis discusses case studies on key players in ICT and suggests major policy conclusions for a field considered fundamental in the context of the EU’s Lisbon Agenda. The theoretical and empirical analysis gives a new and differentiated picture of European ICT where the links between telecommunications dynamics, software innovation and digital services are crucial. Outsourcing, insourcing and offshoring are natural elements of a new digital international division of labour which require reforms in both the EU member countries and at the supranational level.
Intelligent Organizations : Powerful Models for Systemic Management
This innovative book opens a path to overcoming the crisis of management in the face of complexity. The systems approach on which this work is grounded enables the development of the new kind of intelligent organizations so urgently needed. Powerful models, grounded in organizational cybernetics and system dynamics
Intelligent engineering systems and computational cybernetics
A further important component of machine intelligence is a kind of “structural uniformity” giving room and possibility to model arbitrary particular details a priori not specified and unknown.This idea is similar to the ready-to-wear industry, which introduced products, which can be slightly modified later on in contrast to tailor-made creations aiming at maximum accuracy from the beginning. These subsequent corrections can be carried out by machines automatically. This “learning ability” is a key element of machine intelligence.The past decade confirmed that the view of typical components of the present soft computing as fuzzy logic, neural computing.
Information Systems Outsourcing : Enduring Themes, New Perspectives and Global Challenges
This book deals with enduring themes, new perspectives, and global challenges. In addition to classical themes like Sourcing Determinants (Part I), Relationship Aspects (Part II), and Experiences (Part III), we felt it worthwhile to add three new parts. They cover information systems outsourcing from a Vendor and Individual Perspective (Part IV), Application Service Providing (Part V) as well as Offshoring and Global Outsoucing (Part VI). Again we have thoughtfully tried to arrange a compilation of contemporary outsourcing research as a primer and a platform for scientific discourse
Information and Management Systems for Product Customization
This book consists of three parts. In the first part, within the theoretical basics of mass customization are discussed, and within the theoretical context, the main problems that are encountered with the implementation of mass customization are outlined. Part two deals with the development of appropriate information systems for mass customization. Part three discusses the topic of product modularity. More specifically, this part develops a managerial approach or tool to assess and solve complexity issues induced by the variety of needs expressed by customers. Using the tools and the conceptual frameworks developed in INFORMATION AND MANAGEMENT SYSTEMS FOR PRODUCT CUSTOMIZATION, the main problems of mass customization can be resolved. The book is the result of a privately funded, multi-year research project on "Modeling Planning, and Assessment of Business Transformation Processes in the area of Mass Customization."
Inductive logic programming ; 15th International Conference, ILP 2005, Bonn, Germany, August 10-13, 2005, Proceedings
“Change is inevitable.” Embracing this quote we have tried to carefully exp- iment with the format of this conference, the 15th International Conference on Inductive Logic Programming, hopefully making it even better than it already was. But it will be up to you, the inquisitive reader of this book, to judge our success. The major changes comprised broadening the scope of the conference to include more diverse forms of non-propositional learning, to once again have tutorials on exciting new areas, and, for the ?rst time, to also have a discovery challenge as a platform for collaborative work. This year the conference was co-located with ICML 2005, the 22nd Inter- tional Conference on Machine Learning, and also in close proximity to IJCAI 2005, the 19th International Joint Conference on Arti?cial Intelligence. - location can be tricky, but we greatly bene?ted from the local support provided by Codrina Lauth, Michael May, and others. We were also able to invite all ILP and ICML participants to shared events including a poster session, an invited talk, and a tutorial about the exciting new area of “statistical relational lea- ing”. Two more invited talks were exclusively given to ILP participants and were presented as a kind of stock-taking—?ttingly so for the 15th event in a series—but also tried to provide a recipe for future endeavours.
In the Presence of English : Media and European Youth
The starting point for this comparative study on the role of English within the media worlds of European youth is the recognition of the increasing importance of communication with peoples from other cultures and countries. The primary goals of "In the Presence of English: Media and European Youth" are to gain insight into the roles of English in and for Europe; to contribute to discussions of the possibilities of transnational media offerings; to better understand the influence of media in foreign language acquisition and of its role in promoting cross cultural understanding across European cultures; and to better understand the role of English media in the construction of the world view of European youth.
Impact of Pollution on Animal Products
The present workshop contributed highly to the exchange between scientists giving the opportunity for researchers from Central Asia to access to new scientific approaches and methodologies, and for European scientists to assess the extent of the environmental problems in this part of the world. No doubt that these exchanges were the main success of the workshop marked by very stimulating discussions. Such meeting was also the opportunity to put on the first stone of a scientific network focused on the subject of the workshop. The importance of pollution in Central Asia in general and in Kazakhstan in p- ticular is a well-known feature and several references are available on the source and localization of pollution problems in those countries. The references are also abundant on the impact of the environmental failures on human health.
Imaging of Carotid Artery Stenosis
This book take the reader step by step through illustrated descriptions of state-of-the-art imaging techniques that they have helped to develop, and demonstrate that these techniques are crucial in the management of patients. This book covers all facets of imaging in carotid artery stenosis and gives an outlook to future aspects. The "take-home-messages" at the end of each chapter are a quick help in daily practice.
Imagination and Rigor : Essays on Eduardo R. Caianiello's Scientific Heritage
The aim of this Volume of scientific essays is twofold. From one side, by remembering the scientific figure of Eduardo R. Caianiello, it aims at focusing his outstanding contributions - from theoretical physics to cybernetics - which after so many years still represent occasion of innovative paths to be fruitfully followed. It must be stressed the contribution that his interdisciplinary methodology can still be of great help in affording and solving present day complex problems. On the other side, it aims at pinpointing with the help of the scientists contributing to the Volume - some crucial problems in present day research in the fields of interest of Eduardo Caianiello and which are still among the main lines of investigation of some of the Istitutes founded by Eduardo (Istituto di Cibernetica del CNR, IIAS, etc).
Hypoelliptic estimates and spectral theory for Fokker-Planck operators and witten Laplacians
There has recently been a renewal of interest in Fokker-Planck operators, motivated by problems in statistical physics, in kinetic equations and differential geometry. Compared to more standard problems in the spectral theory of partial differential operators, those operators are not self-adjoint and only hypoelliptic. The aim of the analysis is to give, as generally as possible, an accurate qualitative and quantitative description of the exponential return to the thermodynamical equilibrium. While exploring and improving recent results in this direction this volume proposes a review of known techniques on: the hypoellipticity of polynomial of vector fields and its global counterpart; the global Weyl-Hörmander pseudo-differential calculus, the spectral theory of non-self-adjoint operators, the semi-classical analysis of Schrödinger-type operators.
Human Cell Culture ; Vol. VI : Embryonic Stem Cells
If you wish to grow or characterize embryonic stem cells or persuade them to differentiate into a particular cell type, then this book contains information that is vital to your success. The aim is to provide clear simple instructions and protocols for growing, maintaining and characterizing embryonic stem cells and details of the various methods used to make stem cells differentiate into specific cell types.
High-Dynamic-Range (HDR) Vision : Microelectronics, Image Processing, Computer Graphics
This first comprehensive account of high-dynamic-range (HDR) vision focusses on HDR real-time, high-speed digital video recording and also systematically presents HDR video transmission and display. The power of the eye-like, logarithmic optoelectronic conversion concept is demonstrated in machine-vision, medical, automotive, surveillance and cinematic applications, and it is extended to HDR sub-retinal implants for the vision impaired. While the book conveys the overall picture of HDR vision, specific knowledge of microelectronics and image processing is not required. It provides a quantitative summary of the major issues to allow the assessment of the state of the art and a glimpse at future developments. Selected experts share their know-how and expectations in this rapidly evolving art related to the single most powerful of our senses.
