الصفحة 19
الصفحة 19
Behavioral pharmacology of the cholinergic system
The molecular genetics of the cholinergic system including both muscarinic and nicotinic acetylcholine receptors, cholinesterases, acetylcholine synthesis and release have provided significant insights into potential targeting for pharmacological intervention. Cholinergic drugs are being used or evaluated for the treatment of diseases. Thus, this volume aims to broaden our understanding of the current state of cholinergic mechanisms to enable implementation of novel approaches for the development of more effective treatments.
Basis and Treatment of Cardiac Arrhythmias
Incorporating the information related to mechanisms and treatment of cardiac arrhythmia, this book discusses genetics of arrhythmias, cell signalling molecules as potential therapeutic targets and trafficking to the membrane. These approaches and implementations of anti-arrhythmic therapy derive from many decades of research.
Basic & Clinical Pharmacology
Covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. This edition has been extensively updated to provide expanded coverage of transporters, pharmacogenomics, and new drugs Delivers the knowledge and insight needed to excel in every facet of pharmacology!. Encompasses all aspects of medical pharmacology, including botanicals and over-the-counter drugs Major revisions of the chapters on immunopharmacology, antiseizure, antipsychotic, antidepressant, antidiabetic, anti-inflammatory, and antiviral drugs, prostaglandins, and central nervous system neurotransmitters New chapter on the increasingly relevant topic of cannabis pharmacology Each chapter opens with a case study, covers drug groups and prototypes, and closes with summary tables and diagrams that encapsulate important information Revised full-color illustrations provide more information about drug mechanisms and effects and help clarify important concepts Trade Name/Generic Name tables are provided at end of each chapter for easy reference when writing a chart order or prescription Includes descriptions of important new drugs released through May 2019 New and updated coverage of general concepts relating to recently discovered receptors, receptor mechanisms, and drug transporters
Barile's clinical toxicology : Principles and mechanisms ; 3rd ed.
Examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. Special emphasis is placed on signs and symptoms of diseases and pathology caused by toxins and clinical drugs. Includes the source, pharmacological and toxicological mechanism of action, detection and identification in body fluids, and treatment of exposure. An overview of protocols for managing various toxic ingestions, and the antidotes and treatments associated with their pathology, are discussed. In addition, effect of toxins on a limited number of body systems and drug-induced adverse drug reactions are also covered
Bacterial resistance to disinfectants
Bacterial resistance to disinfection is an escalating concern within healthcare facilities, as it poses a significant threat to patient safety and infection control. This research paper aims to explore the various mechanisms underlying bacterial resistance to disinfection, including intrinsic and acquired resistance, as well as the phenomenon of cross-resistance to antibiotic which poses a serious threat worldwide...
Bacterial Genomes and Infectious Diseases
This book imparts fundamental knowledge on the structure, organization, and evolution of bacterial genomes. The value and power of comparative genomics and proteomics, bioinformatics, microarrays, and knockout animal models in analyzing genomes, bacteria-host interactions and disease are demonstrated. Also discussed are the genomes of virulent and nonvirulent strains and species, origin and evolution of pathogens, different models of bacteria-host interactions, and diseases mechanisms.
Augmented Humanity : Being and Remaining Agentic in a Digitalized World
This book will examine the implications of digitalization for the understanding of humanity, conceived as a community of intelligent agency. It addresses important topics across a range of social and behavioral theories and identifies a range of novel mechanisms and their social behavioral effects. Across the book, the author highlights the expansion of intelligent processing capability brought about by digitalization and the challenges this exposes for integrating artificial and human capabilities
Auditory Trauma, Protection, and Repair
Protection and Repair presents recent developments in auditory research and their potential translation to the clinical setting. In particular the authors address the major entities of peripheral auditory trauma, discuss the underlying mechanisms, the central nervous system consequences, protective interventions and finally explore the possibilities to restore cochlear morphology and function.Two themes run through the chapters in this book: cellular homeostasis and cell death. In the broadest sense, all auditory pathologies are disorders of cellular homeostasis.
Atomistic modeling of materials failure
Atomistic Modeling of Materials Failure is an introduction to molecular and atomistic modeling techniques applied to solid deformation and fracture. Focusing on a variety of brittle, ductile and geometrically confined materials, this detailed overview includes computational methods at the atomic scale, and describes how these techniques can be used to model the dynamics of cracks, dislocations and other deformation mechanisms.
Asymmetric hydrogenation and transfer hydrogenation
Details its complex subject matter clearly and plainly and covers everything from catalyst development and reactions to mechanisms and applications in academia and industry. The papers included within come from many of the leading voices in their respective fields and represent the newest and best research available today.
Asset Sales : Their Role in Restructuring and Financing Firms
Examines the corporate asset market and the mechanisms of asset sale transactions. The book then focuses on the theory of finance in asset sales (the efficiency and financing theory) and the extensive empirical literature now available. In light of recent and rapid technological and digital advances, the last section presents new perspectives on analyzing asset sales transactions. Chiefly intended as a primer for PhD students and academics, the book offers a road map of the empirical research landscape and suggests future research directions.
Aspects of physical biology : Biological water, protein solutions, transport and replication
The present volume focuses on three main subtopics (biological water, protein solutions as well as transport and replication), presenting for each of the them the on-going debates on recent results. The role of water in biological processes, the mechanisms of protein folding, the phases and cooperative effects in biological solutions, the thermodynamic description of replication, transport and neural activity, all are subjects that are revised in this volume, based on new experiments and new theoretical interpretations.
Artificiality and sustainability in entrepreneurship : Exploring the unforeseen, and paving the way to a sustainable future
Explores the past, present, and future of artificiality and sustainability in entrepreneurship – the unforeseen consequences and ways to advance to a sustainable future. In particular, it connects artificiality, sustainability and entrepreneurship, intertwining artificial with the specific phenomenon of those novel digital technologies that provoke continuous and significant change in our lives and business. Unlike digital entrepreneurship research, which focuses on digital technology development and management, this book covers processes and mechanisms of sustainable adaptability of entrepreneurs, the business logic of start-ups, and the collaborative behaviours under the mass digital transformation, including the prevalence of artificial intelligence. Some of the questions that this book answers are as follows: How has entrepreneurship reacted to such challenges previously? What lessons have been learned and need to be carried forward? How can entrepreneurship and the artefacts of entrepreneurship respond to current challenges? What should be the mindset of the entrepreneur to assure sustainable adaptation? How to embrace and embed the new business logic?
Artificial Intelligent Techniques for Wireless Communication and Networking
Wireless communication and networking based on AI concepts and techniques are explored in this book, specifically focusing on the current research in the field by highlighting empirical results along with theoretical concepts. The possibility of applying AI mechanisms towards security aspects in the communication domain is elaborated; also explored is the application side of integrated technologies that enhance AI-based innovations, insights, intelligent predictions, cost optimization, inventory management, identification processes, classification mechanisms, cooperative spectrum sensing techniques, ad-hoc network architecture, and protocol and simulation-based environments.
Artificial intelligence and knowledge engineering applications : A bioinspired approach ; 1st international work-Conference on the interplay between natural and artificial computation, IWINAC 2005, Las Palmas, Canary Islands, Spain, June 15-18, 2005, Proceedings, Part II
The computational paradigm considered here is a conceptual, theoretical andformal framework situated above machines and living creatures (two instantia-tions), sufficiently solid, and still non-exclusive, that allows us:1. to help neuroscientists to formulate intentions, questions, experiments, meth-ods and explanation mechanisms assuming that neural circuits are the psy-chological support of calculus;2. to help scientists and engineers from the fields of artificial intelligence (AI)and knowledge engineering (KE) to model, formalize and program the com-putable part of human knowledge;3. to establish an interaction framework between natural system computation(NSC) and artificial system computation (ASC) in both directions, fromASC to NSC (in computational neuroscience), and from NSC to ASC (inbioinspired computation).
Artificial intelligence and data mining approaches in security frameworks
Offers solutions to the problems of security, outlining the concepts behind allowing computers to learn from experience and understand the world in terms of a hierarchy of concepts, with each concept defined through its relation to simpler concepts. provides state of the art approaches of artificial intelligence and data mining in these areas. It includes areas of detection, prediction, as well as future framework identification, development, building service systems and analytical aspects. In all these topics, applications of AI and data mining, such as artificial neural networks, fuzzy logic, genetic algorithm and hybrid mechanisms, are explained and explored. This book is aimed at the modeling and performance prediction of efficient security framework systems, bringing to light a new dimension in the theory and practice. This groundbreaking new volume presents these topics and trends, bridging the research gap on AI and data mining to enable wide-scale implementation. Whether for the veteran engineer or the student, this is a must-have for any library. This groundbreaking new volume: Clarifies the understanding of certain key mechanisms of technology helpful in the use of artificial intelligence and data mining in security frameworks ; Covers practical approaches to the problems engineers face in working in this field, focusing on the applications used every day ; Contains numerous examples, offering critical solutions to engineers and scientists ; Presents these new applications of AI and data mining that are of prime importance to human civilization as a whole
Artificial intelligence : The revolution of drug discovery
The successful application of AI is dependent on the availability of high-quality data, the addressing of ethical concerns, and the recognition of the limitations of AI-based approaches. Moreover artificial intelligence has been a game changer in the past decade. AI proved his worth by making the impossible possible in a short period of time. The health care industry has adopted artificial intelligence technology to deal with the ever-changing therapeutic and drug requirements of patients every day, as we encounter new viruses for which no antidote has been prepared, such as the Corona virus, diseases such as malaria, and the most important problem is the resistance to antibiotics by superbugs that are constantly developing new resistance mechanisms causing harm and confusion.
Applied pharmacology for the dental hygienist ; 9th ed.
Provides an in-depth understanding of the pharmacologic principles needed for safe and effective dental treatment and oral health care. It discusses drug properties and mechanisms of action, dosages, intended effects, interactions, and adverse reactions — both for the medications a patient may already be taking and for the drugs prescribed by the dentist.
Applied pharmacology for the dental hygienist ; 8th ed.
Provides you with an in-depth understanding of the pharmacologic principles needed for safe and effective dental treatment and oral health care. It discusses drug properties and mechanisms of action, dosages, intended effects, interactions, and adverse reactions - both for the medications a patient may already be taking and for the drugs prescribed by the dentist. This new edition has been updated throughout to give you a firm foundation in pharmacology in order to assess and educate patients so they can maintain optimal oral health!
Apoptosis, cell signaling, and human diseases : Molecular mechanisms ; Vol.2
Volume 1 is divided into two sections: "Malignant Transformation and Metastasis" and "Molecular Basis of Disease Therapy." Volume 2 follows a similar structure and is divided into sections entitled "Kinases and Phosphate" and "Molecular Basis of Cell Death." All of the contributors are at the forefront of scientific discovery, and the reviews they present systemically examine the most exciting and innovative aspects of their particular areas of expertise. Researchers will find these volumes of major benefit as they search for novel and more effective treatments for human diseases.
