الصفحة 19
الصفحة 19
Artificial intelligence in medicine ; 10th conference on artificial intelligence in medicine, AIME 2005, Aberdeen, UK, July 23-27, 2005, Proceedings
This book constitutes the refereed proceedings of the 10th Conference on Artificial Intelligence in Medicine in Europe, AIME 2005, held in Aberdeen, UK in July 2005. The 35 revised full papers and 34 revised short papers presented together with 2 invited contributions were carefully reviewed and selected from 148 submissions. The papers are organized in topical sections on temporal representation and reasoning, decision support systems, clinical guidelines and protocols, ontology and terminology, case-based reasoning, signal interpretation, visual mining, computer vision and imaging, knowledge management, machine learning, knowledge discovery, and data mining.
Artificial intelligence applications and innovations II; IFIP TC12 and WG12.5 ; 2nd IFIP conference on artificial intelligence applications and innovations (AIAI-2005), Sept. 7-9, 2005, Beijing, China
Artificial Intelligence is one of the oldest and most exciting subfields of computing, covnering such areas as intelligent robotics, intelligent planning and scheduling, model-based reasoning, fault diagnosis, natural language processing, maching translation, knowledge representation and reasoning, knowledge-based systems, knowledge engineering, intelligent agents, machine learning, neural nets, genetic algorithms and knowledge management. The papers in this volume comprise the refereed proceedings of the Second International Conference on Artificial Intelligence Applications and Innovations,held in Beijing, China in 2005.
Artificial intelligence and machine learning in health care and medical sciences : Best practices and pitfalls
Provides a detailed review of the latest methods and applications of artificial intelligence (AI) and machine learning (ML) in medicine. With chapters focusing on enabling the reader to develop a thorough understanding of the key concepts in these subject areas along with a range of methods and resulting models that can be utilized to solve healthcare problems, the use of causal and predictive models are comprehensively discussed. Care is taken to systematically describe the concepts to facilitate the reader in developing a thorough conceptual understanding of how different methods and resulting models function and how these relate to their applicability to various issues in health care and medical sciences. Guidance is also given on how to avoid pitfalls that can be encountered on a day-to-day basis and stratify potential clinical risks.
Artificial intelligence : Theories, models and applications ; 5th Hellenic Conference on AI, SETN 2008, Syros, Greece, October 2-4, 2008. Proceedings
This book constitutes the refereed proceedings of the 5th Hellenic Conference on Artificial Intelligence, SETN 2008, held at Syros, Greece in October 2008.
Artificial intelligence : The revolution of drug discovery
The successful application of AI is dependent on the availability of high-quality data, the addressing of ethical concerns, and the recognition of the limitations of AI-based approaches. Moreover artificial intelligence has been a game changer in the past decade. AI proved his worth by making the impossible possible in a short period of time. The health care industry has adopted artificial intelligence technology to deal with the ever-changing therapeutic and drug requirements of patients every day, as we encounter new viruses for which no antidote has been prepared, such as the Corona virus, diseases such as malaria, and the most important problem is the resistance to antibiotics by superbugs that are constantly developing new resistance mechanisms causing harm and confusion.
Artificial intelligence : Methodology, systems, and applications ; 13th International Conference, AIMSA 2008, Varna, Bulgaria, September 4-6, 2008. Proceedings
This book constitutes the refereed proceedings of the 13th International Conference on Artificial Intelligence: Methodology, Systems, and Applications, AIMSA 2008, held in Varna, Bulgaria in September 2008.
Artificial immune systems ; 7th International Conference, ICARIS 2008, Phuket, Thailand, August 10-13, 2008. Proceedings
This book constitutes the refereed proceedings of the 7th International Conference on Artificial Immune Systems, ICARIS 2008, held in Phuket, Thailand, in August 2008.
Arrhythmogenic RV cardiomyopathy / dysplasia : Recent advances
This book covers all aspects (biological, pathological, genetic, clinical and therapeutical) of arrhythmogenic right ventricular cardiomyopathy/dysplasia, a recent cardiomyopathy which represents a very high risk of sudden death in the young and in athletes. The monograph presents the results of 5-year research program on ARVC/D supported by grants of both the European Commission and the NIH, which enabled the discovery of seven disease-causing genes, thus opening new avenues for the early identification of affected patients and for sudden death prevention.
Applied biophysics for drug discovery
It is a guide to new techniques and approaches to identifying and characterizing small molecules in early drug discovery. Biophysical methods are reasserting their utility in drug discovery and through a combination of the rise of fragment-based drug discovery and an increased focus on more nuanced characterisation of small molecule binding, these methods are playing an increasing role in discovery campaigns.
Applications of nanotechnology in drug discovery and delivery
Presents complete coverage of the application of nanotechnology in the discovery of new drugs and efficient target delivery of drugs. The book highlights recent advances of nanotechnology applications in the biomedical sciences, starting with chapters that provide the basics of nanotechnology, nanoparticles and nanocarriers. Part II deals with the application of nanotechnology in drug discovery, with an emphasis on enhanced delivery of pharmaceutical products, with Part III discussing toxicological and safety issues arising from the use of nanomaterials
Apoptosis, cell signaling, and human diseases : Molecular mechanisms ; Vol.2
Volume 1 is divided into two sections: "Malignant Transformation and Metastasis" and "Molecular Basis of Disease Therapy." Volume 2 follows a similar structure and is divided into sections entitled "Kinases and Phosphate" and "Molecular Basis of Cell Death." All of the contributors are at the forefront of scientific discovery, and the reviews they present systemically examine the most exciting and innovative aspects of their particular areas of expertise. Researchers will find these volumes of major benefit as they search for novel and more effective treatments for human diseases.
Apoptosis, cell signaling, and human diseases : Molecular mechanisms ; Vol.1
Volume 1 is divided into two sections: “Malignant Transformation and Metastasis” and “Molecular Basis of Disease Therapy.” Volume 2 follows a similar structure and is divided into sections entitled “Kinases and Phosphate” and “Molecular Basis of Cell Death.” All of the contributors are at the forefront of scientific discovery, and the reviews they present systemically examine the most exciting and innovative aspects of their particular areas of expertise. Researchers will find these volumes of major benefit as they search for novel and more effective treatments for human diseases.
Antiviral drug discovery and development
Summarizes antiviral drug design and discovery approaches Provides the latest update in the field of antiviral therapeutics Includes antiviral research of coronaviruses
Antimalarial natural products
Begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine’s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine’s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type.
Antidiabetic plants for drug discovery pharmacology, secondary metabolite profiling, and ingredients with insulin mimetic activity
Takes an in-depth look at the potential pharmacological applications of 11 important antidiabetic plants, examining their antihyperglycemic, hypoglycemic, and anti-lipidemic properties along with current genome editing research perspectives. Plant natural products, or phytoconstituents, are promising candidates for antidiabetic pharmacological actions. The phytoconstituents, such as fl avonoids, terpenoids, saponins, carotenoids, alkaloids and glycosides, play vital roles in the current and future potent antidiabetic drug development programs. Each chapter reviews a particular plant with antidiabetic properties, explaining the therapeutic aspects, its active antidiabetic compounds, and relevant genome editing technology.
Antidepressants Beyond Depression, and Into Bacteria
Antidepressants are one of the most predominant drug groups in the pharmaceutical world, primary care units and the general public. Their original use was majorly for the treatment of depression along with other mental disorders. Today, antidepressant consume over 20% of the medical prescriptions and healthcare plans due to their recently discovered applications outside the psychiatry field. Due to the alarming rise of antibiotic resistance and the slow pace of new drug discovery, the world has been searching frantically for new or alternative drugs with antibacterial activity. Repurposing already FDA- approved drugs for uses that are off-label has become an important preposition in the pharmacy world due to its availability, low risk and low cost.
Anticancer activity in heterocyclic organic structures : A pathway to novel drug development : Part 1
New Directions in Organic & Biological Chemistry, explores the development of cancer therapeutics, focusing on molecular chemistry and advanced drug design approaches. Written by experts in theoretical chemistry and molecular chemistry, they bridge the gap between theoretical chemistry, molecular biology, and drug development. In Part I, they focus on the fundamental properties of heterocyclic compounds and innovative methodologies being employed to enhance therapeutic potential. By exploring various classes of heterocyclic compounds and diverse anticancer mechanisms.
Antibiotic Drug Resistance
This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases.
Anthracycline Chemistry and Biology I : Biological Occurence and Biosynthesis, Synthesis and Chemistry
"This book … covers many different aspects of the origin, chemistry, and biosynthesis of one of the oldest but most important classes of anticancer agents. … In summary, the book is nicely produced, very well edited, and should serve as a valuable source of information … . This book will serve as an inspiration for scientists and students in the areas of chemistry, drug discovery, and biological evaluation. It should be an essential addition to institutional library collections … ."
Animal Models of T Cell-Mediated Skin Diseases
Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly predictive in vitro and in vivo models. The "50th International Workshop of the Ernst Schering Research Foundation" focussed on "Animal Models of T Cell-Mediated Skin Diseases". Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character. The current volume summarises recent advances in animal research that are important for anti-inflammatory drug discovery.
