Bioanalytics : Analytical methods and concepts in biochemistry and molecular biology
Analytical methods are the essential enabling tools of the modern biosciences. This book presents a comprehensive introduction into these analytical methods, including their physical and chemical backgrounds, as well as a discussion of the strengths and weakness of each method. It covers all major techniques for the determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids.
Bioactive Heterocycles V
This volume contains 10 chapters. The contributions are from researchers famous in their respective fields and the chapters contain high quality reviews on topics related to the chemo-biological studies of several different heterocyclic groups. The first chapter from Saracoglu reviews the functionalization of indoles and the pyrroles via Michael additions, as these compounds have potential for their biological activities. In second chapter Men ́endez reviews the chemistry of the welwitindolinones. Topcu and Demirkiran, in the third chapter, describe the chemistry and biological studies of lignans from Taxus species, including their biosynthesis and recent strategies for the synthesis of lignans.
Bioactive Heterocycles IV
This volume contains nine more contributions from expert researchers of the?eld, providing readers with in depth and current research results regarding therespective topics. In the?rst chapter, Flemming et al. review the chemistry, biosynthesis, metabolism and biological activities of tetrahydrocannabinol and its deri- tives. Hansch and Verma contribute to the quantitative structure-activity re- tionship (QSAR) analysis of heterocyclic topoisomerase I and II inhibitors. These inhibitors, knowntoinhibit either enzyme, actasantitumoragentsand are currently used in chemotherapy and in clinicaltrials. In the third chapter, Khan reviews some aspects of molecular modeling studies on biologically active alkaloids.
Bioactive Heterocycles III
Bioactive Heterocycles III provides readers with a comprehensive overview of the most recent breakthroughs in the ?eld of heterocycles. This volume contains 8 chapters written by experts in their respective ?elds from all over the world. The chapters summarize years of extensive research in each area, and providein sight in the new themesofnaturalproduct research.Manyofthe contributors illustrate their laboratory experiences. It's obvious that readers will gain exciting and essential information fromthe volume. In the ?rst chapter, Kayser et al. describe the chemistry, biosynthesis and biological activities of artemisinin, one of the most promising antimalarial molecules, and its related natural peroxides.
Bioactive and therapeutic dental materials
Special attention has been given to bioactive materials developed to induce cells differentiation/stimulation, hard tissue formation and exert antimicrobial actions. New innovations are necessary to continue to help reinforcing existing technologies and to introduce new paradigms for treating dental disease and restoring teeth seriously compromised by caries lesions via biomimetic and more biological operative approaches. Dental bioactive materials is arguably the latest research area in dentistry and thus the amount of new research is overwhelming. However, in this day and age of evidence based practice it important for this new information to be distilled into a practical and understandable format.
Big Data in Context : Legal, Social and Technological Insights
Sheds new light on a selection of big data scenarios from an interdisciplinary perspective. It features legal, sociological and economic approaches to fundamental big data topics such as privacy, data quality and the ECJ’s Safe Harbor decision on the one hand, and practical applications such as smart cars, wearables and web tracking on the other. Addressing the interests of researchers and practitioners alike, it provides a comprehensive overview of and introduction to the emerging challenges regarding big data.All contributions are based on papers submitted in connection with ABIDA (Assessing Big Data), an interdisciplinary research project exploring the societal aspects of big data and funded by the German Federal Ministry of Education and Research.
Benefit/Cost-Driven Software Development : With Benefit Points and Size Points
This book presents a set of basic techniques for estimating the benefit of IT development projects and portfolios. It also offers methods for monitoring how much of that estimated benefit is being achieved during projects. Readers can then use these benefit estimates together with cost estimates to create a benefit/cost index to help them decide which functionalities to send into construction and in what order. This allows them to focus on constructing the functionality that offers the best value for money at an early stage.
Beginning Web Development with Perl
Beginning Perl Web Development: From Novice to Professional introduces you to the world of Perl Internet application development. This book tackles all areas crucial to developing your first web applications and includes a powerful combination of real-world examples coupled with advice. Topics range from serving and consuming RSS feeds, to monitoring Internet servers, to interfacing with e-mail. You'll learn how to use Perl with ancillary packages like Mason and Nagios. Though not version-specific, this book is an ideal read if you have had some grounding in Perl basics and now want to move into the world of web application development. Author Steve Suehring emphasizes the security implications of Perl, drawing on years of experience teaching readers how to think safe, avoid common pitfalls, and produce well-planned, secure code.
Beginning Excel What-If Data Analysis tools : Getting started with goal seek, data tables, scenarios, and solver
Excels what-if data analysis tools let you experiment with your data to project future results. In turn, these predictions will lead to better decision making and unlock the mystery of many business analysis scenarios. For example, what-if data analysis tools will enable you to forecast how lowering the price per unitwhile increasing projected unit salesmight affect your profit margins. Beginning Excel What-If Data Analysis Tools explores the use of Goal Seek, Data Tables, Scenarios, and Solver to help you get insight on your data. This book is focused and to the point, and it provides tutorial treatment of what-if tools in a practical, hands-on manner.
Be data literate : The data literacy skills everyone needs to succeed
It is not enough for a business to have the best data if those using it don't understand the right questions to ask or how to use the information generated to make decisions. Be Data Literate is the essential guide to developing the curiosity, creativity and critical thinking necessary to make anyone data literate, without retraining as a data scientist or statistician.
Basic & Clinical Biostatistics
Provides medical students, researchers, and practitioners with the knowledge needed to develop sound judgment about data applicable to clinical care. This fifth edition has been updated throughout to deliver a comprehensive, timely introduction to biostatistics and epidemiology as applied to medicine, clinical practice, and research. Particular emphasis is on study design and interpretation of results of research.
Barriers and Biases in Computer-Mediated Knowledge Communication : And How They May Be Overcome
This books deals with computer-mediated cooperation and communication scenarios in teaching and learning situations, leisure activities (e.g. laypersons looking for expert information on the internet), and net-based communication at work. Such scenarios will become increasingly important. But the successful use of such computer-mediated settings is not trivial. Cooperative learning and work itself requires special skills and strategies. And the technical settings with sometimes restricted, sometimes new possibilities for communication add problems on top of the cooperation itself. What are the barriers in computer-mediated communication for cooperative learning and work? Which are the most relevant biases in computer-mediated information processing? Based on empirical research the contributors from psychology, education and computer sciences offer different perspectives on the nature and causes of such barriers.
Bacterial regulatory RNA : Methods and protocols
Details new and updated methods used for studying prokaryotic non-coding RNAs and their protein accomplices. Chapters detail discovery of ncRNAs, characterization of their structure, functions, and their interactomes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Azaheterocycles Based on -, ß-Unsaturated Carbonyls
Devoted to heterocyclizations of aliphatic and aromatic, -unsaturated carbonyls with various binucleophiles leading to three-, five-, six and seven-membered partially hydrogenated nitrogen-containing heterocycles. During the last decade interest in these classes of organic c- pounds has been experiencing a scientific renaissance owing to their significant role in biological processes in living cells and diverse effects on physiological activities. In addition, such compounds are also more prevalent from the vi- point of ''classical'' problems of organic chemistry, among them reactivity, chemo- and regioselectivity, tautomerism, conformational analysis and features of their electronic structure. The character of these problems in the case of partially hydrogenated heterocycles differs sufficiently from that for hetero- omatized and perhydrogenated heterocyclic compounds and investigations in this field very often lead to interesting and unusual results. Extensively characterized cyclocondensations of, -unsaturated carbonyls, their synthetic equivalents and their precursors are the most widespread, facile and generally valid pathway to dihydroazaheterocycles.
Autonomous control for a reliable internet of services : Methods, models, approaches, techniques, algorithms, and tools
This open access book was prepared as a Final Publication of the COST Action IC1304 “Autonomous Control for a Reliable Internet of Services (ACROSS)”. The book contains 14 chapters and constitutes a show-case of the main outcome of the Action in line with its scientific goals. It will serve as a valuable reference for undergraduate and post-graduate students, educators, faculty members, researchers, engineers, and research strategists working in this field. The objective of this book is, by applying a systematic approach, to assess the state-of-the-art and consolidate the main research results achieved in this area.
Automated multi-camera surveillance : Algorithms and practice
This book discusses and proposes techniques for development of an automated multi-camera surveillance system for outdoor environments, while identifying the important issues that a system needs to cope with in realistic surveillance scenarios. The goal of the research presented in this book is to build systems that can deal effectively with these realistic surveillance needs.
Asymmetric metal catalysis in Enantioselective Domino reactions
Collects the major progress in the field of enantioselective one-, two-, and multicomponent domino reactions promoted by chiral metal catalysts. It clearly illustrates how enantioselective metal-catalyzed processes constitute outstanding tools for the development of a wide variety of fascinating one-pot asymmetric domino reactions, thereby allowing many complex products to be easily generated from simple materials in one step. The book also strictly follows the definition of domino reactions by Tietze as single-, two-, as well as multicomponent transformations.
Asset allocation and private markets : A guide to investing with private equity, private debt, and private real assets
Asset Allocation and Private Markets provides institutional investors, such as pension funds, insurance groups and family offices, with a single-volume authoritative resource on including private markets in strategic asset allocation. The discussion focuses on private equity, private debt and private real assets, and their correlation with other asset classes to establish optimized investment portfolios.
Assessment of the fate and effects of toxic agents on water resources
Like all limited and vulnerable resources, water has become one of the potential targets of terrorists. Coastal lagoons are especially vulnerable as they are densely populated centers of commerce and/or tourism. This volume addresses the basic scientific concepts that must be integrated by decisionmakers to minimize damages and optimize recovery operations in the aftermath of such an attack. Scientists from many disciplines including water resource management, hydrodynamics, aquatic ecology and social science combine their expertise in an effort to assess and model emergency scenarios for coastal lagoon systems. This case study uses existing numerical models such as-EFCD, WASP and AQUATOX are used to demonstrate how to optimize rapid response and decision-making
Artificial Intelligent Techniques for Wireless Communication and Networking
Wireless communication and networking based on AI concepts and techniques are explored in this book, specifically focusing on the current research in the field by highlighting empirical results along with theoretical concepts. The possibility of applying AI mechanisms towards security aspects in the communication domain is elaborated; also explored is the application side of integrated technologies that enhance AI-based innovations, insights, intelligent predictions, cost optimization, inventory management, identification processes, classification mechanisms, cooperative spectrum sensing techniques, ad-hoc network architecture, and protocol and simulation-based environments.



















