الصفحة 16
الصفحة 16
Drug Selectivity : An Evolving Concept in Medicinal Chemistry
Provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process. The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist.
Drawing for Interior Designers
The perfect guide to producing successful hand drawings of interior designs. Sitting quietly at home, sketchbook in hand, is the ideal way to tackle drawing. In fact, your home is an absolute mine of subjects to draw. Perhaps you already have a plan in your head for a makeover or conversion? This book is filled with practical principles which will help you put your plans down on paper and better express your ideas, for no serious project gets made without a progressive plan. Teaches you some tricks of the trade and conventions which are part of an architect's know-how and which will help you with ideas. Packed with beautiful sketches, provides advice from drawing perspective, floor plans and furniture to rendering rooms and taking down a partition wall.
Dr.phone
Dr phone is a software system that helps in talking with the doctor automatically and easily without the need to go to the doctor's clinic to diagnose the patient's condition. our application presents an available platform to make a video call between the doctor and the patient according to the patient’s needs. The system accepts the patient’s request after choosing an available doctor andthen waits for the doctor to accept his request, if there is no doctor available, the system performs an AI chatbot to the patient's need to give him the appropriate diagnosis. when the call finished the doctor represents medical record including the medicine and the analytics and record the next appointment if it’s needed then send them to the patient's email, the patient also can see the nearest pharmacies or labs according to his location, and finally the patient rates the doctor after the call is finished then payment by his available wallet.
DNA barcoding : Methods and protocols
Covers the latest advancements and methods used to study DNA barcoding. The chapters in this book are organized into six parts: theory, DNA manipulation, specialized barcoding methods, analysis of DNA barcodes, completing a successful DNA barcode project, and barcoding as citizen science. Part One looks at several theoretical issues in DNA barcoding concerned with DNA barcodes that can and should be used. Part Two discusses protocols for processing samples into DNA barcodes, including DNA isolation, sequencing and managing samples, and the resulting DNA barcodes. Part Three explores the next generation of DNA barcoding such as FRET-based detection, dual nanopore detection, skimming, and closed-tube methods. Part Four addresses programs and websites that handle DNA barcoding data, and includes character-based approaches, barcode gap methods, integrated approaches, and Barcode of Life Database
D-Modules, Perverse Sheaves, and Representation Theory
D-modules continues to be an active area of stimulating research in such mathematical areas as algebra, analysis, differential equations, and representation theory. Key to D-modules, Perverse Sheaves, and Representation Theory is the authors' essential algebraic-analytic approach to the theory, which connects D-modules to representation theory and other areas of mathematics. Significant concepts and topics that have emerged over the last few decades are presented, including a treatment of the theory of holonomic D-modules, perverse sheaves, the all-important Riemann-Hilbert correspondence, Hodge modules, and the solution to the Kazhdan-Lusztig conjecture using D-module theory.
Distributed Ledgers : Design and Regulation of Financial Infrastructure and Payment Systems
In this book, Robert Townsend steps back from the hype and controversy surrounding DLT (and the related, but not synonymous, innovations of blockchain and Bitcoin) to offer an economic analysis of what distributed ledgers can do and a blueprint for the optimal design and regulation of financial systems. He analyzes four crucial components of distributed ledgers—ledgers as accounts, e-messages and e-value transfers, cryptography, and contracts—assessing each in terms of both economics and computer science, and forges some middle ground. Relatedly, Townsend highlights hybrid systems in which some of these components allow useful innovation while legacy or alternative pieces deal with the problem of scale.
Distributed Applications and Interoperable Systems ; Vol. 4025 ; 6th IFIP WG 6.1 International Conference, DAIS 2006, Athens, Greece, June 14-16, 2006
This volume contains the proceedings of the IFIP WG 6.1 International Working Conference on Distributed Applications and Interoperable Systems VI held in Bologna, Italy, on June 14-16, 2006. The conference program presents the state of the art in research on d- tributed and interoperable systems. In recent years, distributed applications have indeed gained a practical and widely-known footing in everyday computing.
Distributed and Parallel Systems : In Focus : Desktop Grid Computing
In this book contributors investigate parallel and distributed techniques, algorithms, models and applications; present innovative software tools, environments and middleware; focus on various aspects of grid computing; and introduce novel methods for development, deployment, testing and evaluation.
Discovery Science ; 11th International Conference, DS 2008, Budapest, Hungary, October 13-16, 2008. Proceedings
This book constitutes the refereed proceedings of the 11th International Conference on Discovery Science, DS 2008, held in Budapest, Hungary, in October 2008, co-located with the 19th International Conference on Algorithmic Learning Theory, ALT 2008.
Disasters : Core Concepts and Ethical Theories
Examines disasters from a multidisciplinary perspective. Justification of actions in the face of disasters requires recourse both to conceptual analysis and ethical traditions. Part 1 of the book contains chapters on how disasters are conceptualized in different academic disciplines relevant to disasters. Part 2 has chapters on how ethical issues that arise in relation to disasters can be addressed from a number of fundamental normative approaches in moral and political philosophy. This book sets the stage for more focused normative debates given that no one book can be completely comprehensive. Providing analysis of core concepts, and with real-world relevance, this book should be of interest to disaster scholars and researchers, those working in ethics and political philosophy, as well as policy makers, humanitarian actors and intergovernmental organizations.
Diophantine Approximation : Festschrift for Wolfgang Schmidt
This volume contains 22 research and survey papers on recent developments in the field of diophantine approximation. The first article by Hans Peter Schlickewei is devoted to the scientific work of Wolfgang Schmidt. Further contributions deal with the subspace theorem and its applications to diophantine equations and to the study of linear recurring sequences. The articles are either in the spirit of more classical diophantine analysis or of geometric or combinatorial flavor. In particular, estimates for the number of solutions of diophantine equations as well as results concerning congruences and polynomials are established. Furthermore, the volume contains transcendence results for special functions and contributions to metric diophantine approximation and to discrepancy theory.
Digital Terrain Modelling : Development and Applications in a Policy Support Environment
This book presents a set of papers on Digital Terrain Modelling for Policy Support which aims to be informative and stimulating for both developers and users of digital terrain models. It should also be useful for professi- als who are interested in the wider aspects of the applications of terrain models in support for policies and decision making. There is an increasing demand for regional and continental scale data for use in environmental modelling and spatial analysis to support envir- mental policy development and implementation. Important environmental processes act at regional and continental scales, for example climatic change inducing floods and soil erosion, and management of these pr- esses for the sustainable development of society requires policies to be - plied at the corresponding scales. One of the most important factors inf- encing these environmental processes which act on the earth’s surface is the surface topography, hence the need for extensive, harmonised digital terrain models.
Digital Phase Lock Loops : Architectures and Applications
This exciting new book covers various types of digital phase lock loops. It presents a comprehensive coverage of a new class of digital phase lock loops called the time delay tanlock loop (TDTL). It also details a number of architectures that improve the performance of the TDTL through adaptive techniques that overcome the conflicting requirements of the locking rage and speed of acquisition. These requirements are of paramount importance in many applications including wireless communications, consumer electronics and others. Digital Phase Lock Loops then illustrates the process of converting the TDTL class of digital phase lock loops for implementation on an FPGA-based reconfigurable system. These devices are being utilized in software-defined radio, DSP-based designs and many other communication and electronic systems to implement complex high-speed algorithms.
Diapause in Aquatic Invertebrates : Theory and Human Use
Contributors to this new book are leaders in the field of diapause studies, and many authors were participants at a recent workshop on diapause in aquatic invertebrates (Pallanza, Italy 2003). The book consists of two major parts, as indicated in its title: Phenomenology of diapause and significance of this adaptation in scientific and practical uses. Application to newly developing areas such as cultivation of live food, like rotifers or Artemia, in modern aquaculture is covered, as are aspects of diapause that promote the colonization of new environments by facilitating the passive transport of resting stages of invasive species. Creation of artificial ecosystems outside of the Earth’s biosphere using dormant propagules becomes an actual possibility as humankind develops plans to colonize our nearest planets.
Diagnosis of endometrial biopsies and curettings : A practical approach
Diagnosis of Endometrial Biopsies and Curettings, 2nd edition, revised and now with color illustrations, continues the tradition of its predecessor as being the concise and complete diagnostic guide to the endometrial biopsy. The text is structured to present a logical approach to formulating a pathologic diagnosis from the diverse array of tissue received in the surgical pathology laboratory with an emphasis on differential diagnosis. More than 220 illustrations complement the text, with 70 of them in full color throughout. Each chapter includes a section on "Clinical Queries and Reporting", which summarizes the features that must be discussed in the final pathology report. The authors are two prominent gynecologic pathologists, and this book is derived from their long-running Short Course presented at the International Academy of Pathology.
Diagnosis of Aging Skin Diseases
Diagnosis of Aging Skin Diseases provides the clinician with an encyclopedia of geriatric dermatoses that can be used on rounds or in a reference environment. It provides a structured illustrated review of the various lesions encountered, which will make this an invaluable reference resource for all physicians dealing with older skin.
Detection of Liquid Explosives and Flammable Agents in Connection with Terrorism
The organization of an Advanced Research Workshop with the title “Detection and Disposal of Liquid Explosives and Flammable Agents in Connection with Terrorism” was motivated by international findings about activities in this field of application. This ARW followed a meeting about the “Detection of Disposal Improvised Explosives” (St. Petersburg, 2005). Both items show the logistic problems as one of the lessons, terrorists have to overcome. These problems are connected with the illegal supply and transport of explosives and fuels and as counter-measure the detection of these materials. The invention of liquid explosives goes back to the middle of the 19th century and was used for special purposes in the commercial field of application. Because of the high sensitivity of liquid explosives against mechanical shock, caused by adiabatic compression of air-bobbles producing “hot spots” as origin of initiation the commercial application was not very successful. Because of this high risk, liquid explosives are not used in military or commercial application with some exceptions. In the commercial field explosives as slurries or emulsions consisting of suitable salts (Ammoniumnitrate etc.) and water are used to a large extend because of their high insensitivity. In many cases these slurries or emulsions were unfit for terrorist actions, because of their low sensitivity, large critical diameter and using in confinement. In the military field liquid explosives are used in World War I and II as bomb-fillings.
Detection and Disposal of Improvised Explosives
It including: Methods of detection of Improvised Explosives (IE). Methods of detection of Improvised explosives devices (IED). Disposal and safe handling of ID and IED. The treatment of detection methods may be divided in the following groups: Overview about the different methods; Trace- and vapor detection; Electromagnetic methods; Neutron methods; Laser techniques. Because of different definitions of Improvised Explosives the parti- pants of the workshop agreed after some discussions with the following definition: An Improvised Explosive (IE) can be any chemical compound or mixture capable of an explosive reaction. They are normally easily prepared by a knowledgeable layman under simple conditions. Components of IE are typically inorganic salts containing molecular bound oxygen like nitrates, chlorates or perchlorates etc. or organic compounds with nitro-, nitami- or nitrate-groups or peroxides. Admixtures of military or commercial explosive materials are also used. From the chemical point of view IE can be divided into the following types: Salts containing chemical groups with oxygen (like nitrates, chlorates or perchlorates etc.) in mixtures with combustible substances like carbon-hydrogen compounds.
Design of Wireless Autonomous Datalogger ICs
The book starts with a comprehensive introduction on the most important design aspects and trade-offs for miniaturized low-power telemetric dataloggers. After the general introduction follows an in-depth case study of an autonomous CMOS datalogger IC for the registration of in vivo loads on oral implants. After tackling the design of the datalogger on the system level, the design of the different building blocks is elaborated in detail, with emphasis on low power
Design of High Voltage xDSL Line Drivers in Standard CMOS
The book focusses on the line driver, the most demanding building block of the xDSL modem for lowering power. To reduce the cost, the cheapest technology is selected: standard CMOS, without any extra process options to increase the nominal supply voltage.
