الصفحة 15
الصفحة 15
Mechanisms of the Glaucomas : Disease Processes and Therapeutic Modalities
In this book leaders in the various fields of glaucoma review our current understanding of glaucoma from epidemiology and genetics through molecular, cellular and tissue responses to the mechanisms of the glaucomas and the mechanisms by which we manage them.
Mechanisms of Insulin Action
More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. In addition, between 17 and 40 million people have insulin resistance, impaired glucose tolerance, or the cluster of abnormalities referred to variably as the metabolic syndrome, the dysmetabolic syndrome, syndrome X, or the insulin resistance syndrome. In all of these disorders, a central component of the pathophysiology is insulin resistance, i.e., reduced responsiveness to insulin in tissues such as muscle, fat and liver. Insulin resistance is also closely linked to other common health problems, including obesity, polycystic ovarian disease, hyperlipidemia, hypertension, and atherosclerosis. In this book, we will attempt to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. We explore insulin action at the most basic levels, through complex systems. The book will be appealing to basic and clinical scientists.
Mechanics of Structural Elements : Theory and Applications
The book systematically presents variational principles and methods of analysis for applied elasticity and structural mechanics. The variational approach is used consistently for both, constructing numerical procedures and deriving basic governing equations of applied mechanics of solids; it is the derivation of equations where this approach is most powerful and best grounded by mathematics. The book is oriented towards experts in civil engineering, researchers, developers of software for mechanical strength, stability, and oscillation analysis; it can be used by practical engineers who employ software tools to do their job and who want to know more about the theoretical background of the strength analysis. The book will be useful to senior and postgraduate students of engineering, to professors of structural analysis at civil or mechanical engineering departments of technical universities.
Mechanics and natural philosophy before the scientific revolution
This volume deals with a variety of moments in the history of mechanics when conflicts arose within one textual tradition, between different traditions, or between textual traditions and the wider world of practice. Its purpose is to show how the accommodations sometimes made in the course of these conflicts ultimately contributed to the emergence of modern mechanics.
Measuring the Business Value of Cloud Computing
The importance of demonstrating the value achieved from IT investments is long established in the Computer Science (CS) and Information Systems (IS) literature. However, emerging technologies such as the ever-changing complex area of cloud computing present new challenges and opportunities for demonstrating how IT investments lead to business value.
Measuring Precipitation from Space : EURAINSAT and the Future
More than 20 years after the last book on the subject the worldwide precipitation community has produced a comprehensive overview of its activities, achievements, ongoing research and future plans. Measuring Precipitation from Space presents state-of-the-art rainfall estimation algorithms, validation strategies, precipitation modelling, and assimilation in numerical weather prediction models. Clouds and precipitation observations and modelling are addressed for the improvement of the rainfall product quality. Special attention is given to the applications to monitoring and forecasting weather events and to climate monitoring in a frame of growing public interest.
Measuring human trafficking : Complexities and pitfalls
Measuring Human Trafficking needs to be read by scholars, professionals, and policymakers in the criminology and human rights fields. The ideas in this important volume can serve to improve the global knowledge base, strengthen coordination between agencies, and develop more effective solutions for combating this most pressing moral issue.
Measurement, Control, and Communication Using IEEE 1588
IEEE 1588, published in November 2002, is a technology new to the engineering community expanding the performance capabilities of Ethernet networks so that they become relevant for measurement and control; this monograph embodies the first unified treatment of the associated technology, standards and applications. Readers unfamiliar with IEEE 1588 will gain understanding of the context of the technology it represents and, from three chapters of case studies, its role in a variety of application settings.
Means, Ends and Medical Care
In this remarkable book, Gary Wright brings his thirty years of experience as a physician in pediatric and family medicine together with his Ph.D. in philosophy to address the important problem of the nature of good medical reasoning. Wright gives a brilliant analysis of the complex internal structure of our concepts of health and disease, showing that our present models are wholly incapable of dealing with the realities of actual human disease. He then shows the error of assuming that we always know in advance what the medical and moral ends are for any medical situation. This leads to a radical questioning of so-called "rational actor" or "economic" models of rationality that are popular in medicine today.
Meaning-Making for Living : The Emergence of the Presentational Self in Children’s Everyday Dialogues
This Brief analyzes the dynamics in which children’s selves emerge through their everyday activities of meaning construction, both in their relationships with family and within school education. It begins with a discussion of new psychological inquiries into children's selves and builds upon the innovative theoretical notion of the Presentational Self, developed by the author over the last decade. The book illustrates how the observation of children’s meaning construction in their everyday lives becomes a starting point for theoretical and empirical inquiries into child development and gives a framework that promotes new inquiries in this area. The book describes the Presentational Self Theory as a sense of how the notion of the Self is being worked upon in everyday life encounters. Chapters feature in-depth analyses of exchanges between adults and children in the Japanese cultural context.
Meaning in Mathematics Education
This book presents a wide variety of theoretical reflections and research results about meaning in mathematics and mathematics education based on long-term and collective reflection by the group of authors as a whole. It is the outcome of the work of the BACOMET (BAsic COmponents of Mathematics Education for Teachers) group who spent several years deliberating on this topic. The ten chapters in this book, both separately and together, provide a substantial contribution to clarifying the complex issue of meaning in mathematics education.
Meaning in Action : Constructions, Narratives, and Representations
are far from genetically ? xing what behavioral preferences they may possess. Instead, learning mechanisms offer a ? exible way of attaining locally important cultural knowledge within temporal windows of opportunity as has been convi- ingly shown by research in language and culture attainment. Similar mechanisms are likely to exist for other social capacities, such as mate preferences, for example. It is this role of our biological inheritance that social science must appreciate in order to furnish a more complete understanding of human behavior. Within the natural range of variation of capacities and armed with biologically conditioned learning mechanisms we live out lives of meaning – in which we hold some things to be real, rational, valuable or morally right, and others not. It is this world of meaning in which we ? nd love and hate, struggles for justice, power, and money, and the dramas that lend to life both its depth and passion.
Meaning and Use
The second Jerusalem Philosophical Encounter was held in Jerusalem on April 25-28, 1976, The topic of the symposiumwas Meaning and Use. For Bar-Hillel, the question 'meaning or use?' was of great importance, one which he took as a question of priorities. Which approach to natural language is prior: the formal, semantical approach, which accords a central position to the truth functional concept of meaning and to the theory of reference, or rather the alternative approach which accords the central position to linguistic commu nication and prefers dealing with speech acts to dealing with Statements? Bar Hillel's answer to this question, in his later years, can be summed up by our title, meaning and use: neither approach deserves priority, each is equally necessary, and they both complement each other.
Meaning and Language : Phenomenological Perspectives
This book is the first anthology to provide a wide-ranging picture of how phenomenology relates to language. It contains both in-depth studies on new aspects of language in Husserl’s thought as well as original phenomenological research that explores the respective potentials and limits of linguistic expression and conceptualization.
Mean Oscillations and Equimeasurable Rearrangements of Functions
Various applications of equimeasurable function rearrangements to the ''best constant"-type problems are considered in this volume. Several classical theorems are presented along with some very recent results. In particular, the text includes a product-space extension of the Rising Sun lemma, a product-space version of the John-Nirenberg inequality for bounded mean oscillation (BMO) functions with sharp exponent, a refinement of the Gurov-Reshetnyak lemma, sharp embedding theorems for Muckenhoupt, Gurov-Reshetnyak, reverse Hölder, and Gehring classes, etc. This volume is interesting for graduate students and mathematicians involved with these topics.
MDATA : A New Knowledge Representation Model: Theory, Methods and Applications
This book introduces a new knowledge representation model called MDATA (Multi-dimensional Data Association and inTelligent Analysis). By modifying the representation of entities and relations in knowledge graphs, dynamic knowledge can be efficiently described with temporal and spatial characteristics. The MDATA model can be regarded as a high-level temporal and spatial knowledge graph model, which has strong capabilities for knowledge representation. This book introduces some key technologies in the MDATA model, such as entity recognition, relation extraction, entity alignment, and knowledge reasoning with spatiotemporal factors. The MDATA model can be applied in many critical applications and this book introduces some typical examples, such as network attack detection, social network analysis, and epidemic assessment.
Maxillofacial surgery and craniofacial deformity: practices and updates
Collects various aspects of facial and cranial deformities in one single textbook in order to have a systematic way of thinking when approaching these interconnected manifestations. Furthermore, other associated social aspects of health care are integrated to give a wider view of the problem and some important considerations of care.
Matrix Metalloproteinases in Tissue Remodelling and Inflammation
Matrix metalloproteinases (MMPs) are proteolytic enzymes believed to be involved in many physiological and pathological processes associated with inflammatory reactions. This volume presents new advances in the involvement of MMPs in various diseases associated with inflammatory processes. Moreover, the recent development of selective and non selective inhibitors of MMPs provides new insights in the relationship between activation of inflammatory cells and tissue remodelling and advises new therapeutic possibilities for the treatment of inflammatory diseases.
Mathematics teacher education in the Andean region and Paraguay : A comparative analysis of issues and challenges
This Open Access book is an excellent synthesis of the initial and continuing preparation for Mathematics Teaching in Bolivia, Ecuador, Paraguay and Peru, from which comparative analyses can be made that show similarities and differences, and highlight various perspectives. This book brings to the international Educational Community an important collection of experiences and ideas in the Mathematics Education of four Latin-American countries in the developing Andean region and Paraguay. The dissemination of these results can promote the search for international collaborative actions in a wider scale.
Mathematics of Financial Markets
This book presents the mathematics that underpins pricing models for derivative securities, such as options, futures and swaps, in modern financial markets. The idealized continuous-time models built upon the famous Black-Scholes theory require sophisticated mathematical tools drawn from modern stochastic calculus. However, many of the underlying ideas can be explained more simply within a discrete-time framework. This is developed extensively in this substantially revised second edition to motivate the technically more demanding continuous-time theory, which includes a detailed analysis of the Black-Scholes model and its generalizations, American put options, term structure models and consumption-investment problems. The mathematics of martingales and stochastic calculus is developed where it is needed.
