الصفحة 14
الصفحة 14
Teaching Entrepreneurship : Cases for Education and Training
This book offers various examples for teaching and learning entrepreneurship in academia. Readers gain insight into the real work and experience of entrepreneurship educators from universities and business schools across Europe, especially from Northern Europe. The practice-oriented case studies also highlight the different, sometimes country-dependent contexts of teaching and the challenges for entrepreneurship education and promotion. Moreover, different solutions for the problems entrepreneurship educators face in providing effective learning environments are demonstrated. Thus, the case studies are also an inspiring text book and teaching material.
Teacher Transition into Innovative Learning Environments : A Global Perspective
This book focuses on how the design and use of innovative learning environments can evolve as teaching practices and education policies change. It addresses how these new environments are used, how teachers are adapting their practices, the challenges that these changes pose, and the effective evaluation of these changes.
Taylors Diagnostic and Therapeutic Challenges : A Handbook
With a clinician’s experienced eye, Robert B. Taylor, MD, has carefully chosen chapters from his widely trusted reference, Family Medicine: Principles and Practice, Sixth Edition, that focus on selected problems that clinicians often find a challenge to diagnose or treat. Respected contributors share their wisdom and provide readers with a sense of direction as they consider care options. Chapters address the diagnosis of a variety of difficult diseases and disorders, such as diabetes mellitus, fatigue, and chronic pain. The etiology of conditions is also highlighted to help physicians select the most effective therapeutic courses of treatment. Management strategies for complicated problems, such as alcoholism and obesity, are examined as well. By covering some of medicine’s most challenging clinical problems, this pocket-sized handbook is a convenient timesaving source. The text is invaluable for family physicians and other clinicians who provide primary care, including general internists, general pediatricians, nurse practitioners, and physician assistants.
Tax and Corporate Governance
The interaction of tax and corporate governance forms an emerging issue both in business and administrative practice and in academic research. International organisations (OECD, EC) have begun to explore the effects corporate governance rules exert on the tax policy of large business; governments try to employ corporate and securities law as a means to further their fiscal interest. Academic research shows that well-known principal-agent and capital market problems are strongly influenced by tax considerations. Against this background, this volume is the first to present a fully-fledged overview of the interdependence of tax and corporate governance. Not only the basic political, legal and economic questions but also major topics like income measurement, shareholding structures, corporate social responsibility and tax shelter disclosure are covered extensively by leading authors.
Task design In mathematics education : An ICMI study 22
The authors develop explicit understandings of the opportunities and difficulties involved in designing and implementing tasks and of the interfaces between the teaching, researching and designing roles – recognising that these might be undertaken by the same person or by completely separate teams. Tasks generate the activity through which learners meet mathematical concepts, ideas, strategies and learn to use and develop mathematical thinking and modes of enquiry. Teaching includes the selection, modification, design, sequencing, installation, observation and evaluation of tasks. The book illustrates how task design is core to effective teaching, whether the task is a complex, extended, investigation or a small part of a lesson; whether it is part of a curriculum system, such as a textbook, or promotes free standing activity; whether the task comes from published source or is devised by the teacher or the student.
Targeted Therapies in Cancer
Oncological chemotherapy has been encumbered by its poor selectivity because most antiproliferative drugs are toxic not only to tumor cells but also to important populations of the body’s non-neoplastic cells. The resultant problems with unwanted side effects are compounded by difficulties in predicting the desired effectivity of chemotherapy in individual patients. This unsatisfactory situation has driven intensive research and development towards more specific and less toxic anticancer drugs over the last few decades. Several results of these efforts have reached the clinic and an even greater number are now in preclinical testing. Common to all these targeted therapies is their interaction with defined molecules present on cancer cells, which adds various degrees of increased selectivity to their toxic effects. As a consequence, detecting the target molecule on tumors before therapy holds great diagnostic potential for predicting the efficacy of the drug and personalizing therapy. This book aims to present translational scientists and clinicians with an integrated critical view on the theories, mechanisms, problems and pitfalls of the targeted therapy approach.
Targeted Radionuclide Tumor Therapy : Biological Aspects
The last three decades have provided opportunities to explore the potential of treating malignant diseases with antibodies or other targeting molecules labelled with nuclides. The expanding array of new targeting molecules (recombinant antibodies or peptides) may increase the therapeutic efficacy. The title of this book "Targeted Radionuclide Tumor Therapy – Biological aspects" was selected to reinforce the concept that a major focus was devoted to understanding the biological effects of targeting and radiation. Furthermore, our rapidly expanding knowledge of low dose-rate effects, different types of cell death, autosensitization and the increasingly likely existence of cancer stem cells suggests to us that even more efficient approaches in targeting might be possible in the future.
Targeted metallo-drugs : Design, development, and mode of action
Inspired by the clinical success of cisplatin as a leading anticancer drug but mindful of the shortcomings associated with its use including dose-limiting toxic side effects and acquired or intrinsic drug resistance, scientists across the globe have been endeavoring to identify new metallo-drugs for therapeutic exploitation. This has led to innovative metallo-drug candidates that (i) enhance cancer cell selectivity, thus reducing toxic side effects, and/or (ii) possess new modes of action to improve efficacy and also target resistance pathways. This and more are captured in MILS- 24 which consists of 12 comprehensive, well-illustrated, and up to date chapters with over 1600 citations, 100 figures, and 10 tables with key contributions from 32 international experts from Europe, Asia, and North and South America. MILS- 24 not only keeps the scientific community abreast of latest developments, it also serves as an invaluable resource to stimulate further research on targeted metallo-drug design and development.
Targeted cancer therapy in biomedical engineering
Highlights the role of Biomedical Engineering (BME) used in diagnosis (e.g., body scanners) and treatment (radiation therapy and minimal access surgery in order to prevent various diseases). In recent years, an important progress has been made in the expansion of biomedical microdevices which has a major role in diagnosis and therapy of cancer. When fighting cancer, efficacy and speed are of the utmost importance. A recently developed microfluidic chip has enabled a breakthrough in testing the efficacy of specialized cancer drugs. Effective cancer-targeting therapies will require both passive and active targeting strategies and a thorough understanding of physiologic barriers to targeted drug delivery. Targeted cancer treatments in development and the new combinatorial approaches show promise for improving targeted anticancer drug delivery and improving treatment outcomes.
Targeted Cancer Therapy
In the era of personalized medicine, cancer treatment has become a model for the use of targeted therapeutics. Leaving behind the "one size fits all" approach to cancer care, this book provides the practicing oncologist with an overview of the advances in treatment and an understanding of the implementation of new therapeutic agents. Targeted Cancer Therapy is divided into twenty chapters covering specific hematologic malignancies and solid tumors, targeted and functional imaging, and combination therapies. Each disease specific chapter includes up-to-date information on investigational and FDA approved therapies which will enhance the reader’s ability to prescribe effective drug regimens. This includes combinations of therapies and therapeutic modalities to overcome drug resistance.
Target Cancer Therapy
Cancer is known as abnormal growth of cells due to genetic mutations associated with other factors such as smocking, overweight, physical inactivity and changing reproductive pattern. Each mutation drives a wave of cellular multiplication associated with gradual increases in tumor size, disorganization and malignancy. Cancer treatment are invasive, painful, expensive and often creating long term negative side effect. The most common cancer treatment are chemotherapy, radiation therapy, surgery, hormone therapy, stem cell transplant and the modest one is targeted cancer therapy. Target cancer therapies are drugs or other substances that block the growth and spread of cancer by interfering with specific molecules that are involved in the growth, progression and spread of cancer. Targeted therapies are currently focus of much anticancer drug development, they are cornerstone of precision medicine, a form of medicine that uses information about person’s genes and proteins to prevent, diagnose and treat disease.
Tall buildings : Structural systems and aerodynamic form
The structural challenges of building 800 metres into the sky are substantial, and include several factors which do not affect low-rise construction. This book focusses on these areas specifically to provide the architectural and structural knowledge which must be taken into account in order to design tall buildings successfully. In presenting examples of steel, reinforced concrete, and composite structural systems for such buildings, it is shown that wind load has a very important effect on the architectural and structural design. The aerodynamic approach to tall buildings is considered in this context, as is earthquake induced lateral loading.
System-level design techniques for energy-efficient embedded systems
System-Level Design Techniques for Energy-Efficient Embedded Systems addresses the development and validation of co-synthesis techniques that allow an effective design of embedded systems with low energy dissipation. The book provides an overview of a system-level co-design flow, illustrating through examples how system performance is influenced at various steps of the flow including allocation, mapping, and scheduling. The book places special emphasis upon system-level co-synthesis techniques for architectures that contain voltage scalable processors, which can dynamically trade off between computational performance and power consumption. Throughout the book, the introduced co-synthesis techniques, which target both single-mode systems and emerging multi-mode applications, are applied to numerous benchmarks and real-life examples including a realistic smart phone.
Systematic methodology for real-time cost-effective mapping of dynamic concurrent task-based systems on heterogeneous platforms
Systematic Methodology for Real-Time Cost-Effective Mapping of Dynamic Concurrent Task-Based Systems on Heterogeneous Platforms gives an overview of the state-of-the-art in system-level design trade-off explorations for concurrent tasks running on embedded heterogeneous multiple processors. The targeted application domain covers complex embedded real-time multi-media and communication applications.
Systematic Investing in Credit
Focuses on their latest cutting-edge research into the appropriate role of credit as an asset class, the dynamics of credit benchmarks, and potential ways to benefit from equity information to construct effective credit portfolios. It is must-read material for all serious credit investors.
System Verilog for Verification : A Guide to Learning the Testbench Language Features
Povides practical information for hardware and software engineers using the SystemVerilog language to verify electronic designs. It contains a new chapter covering programs and interfaces as well as chapters with updated information.
Symmetry Rules : How Science and Nature are founded on Symmetry
When we use science to describe and understand the world around us, we are in essence grasping nature through symmetry. In fact, modern theoretical physics suggests that symmetry is a, if not the, foundational principle of nature. Emphasizing the concepts, this book leads the reader coherently and comprehensively into the fertile field of symmetry and its applications. Among the most important applications considered are the fundamental forces of nature and the Universe. It is shown that the Universe cannot possess exact symmetry, which is a principle of fundamental significance. Curie's principle - which states that the symmetry of the effect is at least that of the cause - features prominently. An introduction to group theory, the mathematical language of symmetry, is included. This book will convince all interested readers of the importance of symmetry in science. Furthermore, it will serve as valuable background reading for all students in the physical sciences.
Symmetry and Heterogeneity in High Temperature Superconductors
This book is a collection of the papers presented at the workshop on “Symmetry and Heterogeneity in High Tc Superconductors” The object of the workshop was the quantum mechanism that allows the macroscopic quantum coherence of a superconducting condensate to resist to the attacks of high temperature. Solution to this problem of fundamental physics is needed for the design of room temperature superconductors, for controlling the decoherence effects in the quantum computers and for the understanding of a possible role of quantum coherence in living matter that is debated today in quantum biophysics. The discussions in the informal and friendly atmosphere of Erice was on new experimental data showing that high T in doped cuprate perovskites is c related with the nanoscale phase separation and the two component scenario, the two-band superconductivity in magnesium diboride and the lower symmetry in the superconducting elements at high pressure.
Switched Linear Systems : Control and Design
Switched linear systems have a long history in the control literature but-along with hybrid systems more generally-they have enjoyed a particular growth in interest since the 1990s. The large amount of data and ideas thus generated have, until now, lacked a co-ordinating framework to focus them effectively on some of the fundamental issues such as the problems of robust stabilizing switching design, feedback stabilization and optimal switching.
Sustainable structures and buildings
Includes detail on various structures, buildings, and building materials from different structural and sustainability perspectives. It describes how the building industry is vital for the achievement of the sustainable development goals, namely, economic growth, social progress, and the effective protection of the environment. The aim of this collection is to foster the design and construction of sustainable structures and buildings to reduce the environmental load, connect with the environment, and benefit the health of occupants.
