الصفحة 138
الصفحة 138
Biocombinatorial approaches for drug finding
Genome- and proteome-based research is generating a significant increase in the number of available drug targets. Correspondingly there is an increasing need for novel, diverse compounds, particularly based on natural compounds, as screening resource
Biochemistry
Biochemistry and the organization of cells -- Water : the solvent for biochemical reactions -- Amino acids and peptides -- The three-dimensional structure of proteins -- Protein purification and characterization techniques -- The behavior of proteins : enzymes -- The behavior of proteins : enzymes, mechanisms, and control -- Lipids and proteins are associated in biological membranes -- Nucleic acids : how structure conveys information -- Biosynthesis of nucleic acids : replication -- Transcription of the genetic code : the biosynthesis of RNA -- Protein synthesis : translation of the genetic message -- Nucleic acid biotechnology techniques -- Viruses, cancer, and immunology -- The importance of energy changes and electron transfer in metabolism -- Carbohydrates -- Glycolysis
Bioceramics and alternative bearings in joint arthroplasty ; 12th BIOLOX® Symposium Seoul, Republic of Korea September 7 - 8, 2007. Proceedings
th ® Dear Colleague and Participant of the 12 International BIOLOX Symposium ® It is an honor for CeramTec to have the BIOLOX Symposium in Asia. The selection of Seoul, Korea as the site was a difficult one due to the fact that there are many wonderful location options in this dynamic and fast growing region of the world. The selection was made easier by the outstanding support of our Symposium Chairman, Prof. Chang, as well as the excellent airline service and meeting facilities present in Seoul. We hope that conducting the Symposium in this region will serve as a foundation for the increased recognition of the potential patient benefits to be derived from the use of ceramics and other alternative bearing technologies in Korea, China, India, Japan and the rest of the countries of the region.
Bio-based Building Skin
This book provides a compendium of material properties, demonstrates several successful examples of bio-based materials’ application in building facades, and offers ideas for new designs and novel solutions. It features a state-of-the-art review, addresses the latest trends in material selection, assembling systems, and innovative functions of facades in detail. Selected case studies on buildings from diverse locations are subsequently presented to demonstrate the successful implementation of various biomaterial solutions, which defines unique architectural styles and building functions. The structures, morphologies and aesthetic impressions related to bio-based building facades are discussed from the perspective of art and innovation; essential factors influencing the performance of materials with respect to functionality and safety are also presented. Special emphasis is placed on assessing the performance of a given facade throughout the service life of a building, and after its end.
Bioanalytical aspects in biological therapeutics
The book discusses the challenges and considerations for bioanalytical support, covering a wide range of central topics in the field, including overview and basic immunology for testing of biological therapeutics, pharmacokinetic aspects, clinical immunogenicity prediction and testing, biomarker testing, biotransformation assessment for biologics, statistical aspects of bioanalytical testing, regulatory expectations, and more
Bioactives and pharmacology of medicinal plants : Vol.1
Bioctives and Pharmacology of Medicinal Plants, concisely presents an abundance of important information on the bioactive and pharmacological properties of medicinal plants. It provides valuable comprehensive research and studies on bioactive phytocompounds of over 68 important medicinal plants with beneficial properties. For each species included in the volume, a brief introduction is given along with their bioactive compounds and chemical structures, followed by their chief pharmacological activities that include antiviral, antimicrobial, antioxidant, anti-cancer, anti-inflammatory, antidiabetic, hepatoprotective, nephroprotective, and cardioprotective activities. A review of the published literature on pharmacological activities on each species is included also, providing a thorough resource on each of the plants covered in the volume.
Bioactives and pharmacology of Legumes
A variety of bioactives and therapeutics from the legume family (Fabaceae or Leguminosae) are thoroughly detailed. For each species included in the volume, a brief introduction is given, the plant’s bioactive compounds are listed, and its chemical structures shown, followed by their pharmacological activities. Many of these plants have medicinal activities that include antiviral, antimicrobial, antioxidant, anticancer, anti-inflammatory, and antidiabetic, hepatoprotective, nephroprotective and cardioprotective. The biochemical characteristics of the 37 plants included, such as the type of starch, protein, and fibers, can be exploited as binders, excipients, thickeners, and dispersants in the formulation of various products in the pharmaceutical industry. The published literature on the pharmacological activities on each species is reviewed and presented in a concise and clear manner.
Bioactive Molecules and Medicinal Plants
Use of medicinal plants is as old as human civilization and continuous efforts are being made to improve medicinal plants or produce their products in high amounts through various technologies. About 200,000 natural products of plant origin are known and many more are being identifed from higher plants and microorganisms. Some plant-based drugs have been used for centuries and there is no alternative medicine for many drugs, such as cardiac glycosides. However, natural products research was sidelined to pave the way for com- natorial chemistry, which was expected to produce large numbers of synthetic compounds for high-throughput screening (HTS). This line of work has failed to deliver desirable results. Moreover, it is not possible for all pharmaceutical companies and institutions to adopt costly HTS technology. Therefore, medi- nal plants and their bioactive molecules are always in demand and are a central point of research. While planning this book, we endeavored to incorporate - ticles that cover the entire gamut of current medicinal plants research.
Bioactive Heterocycles II
As part of the series Topics in Heterocyclic Chemistry, this volume titled Bio- tive Heterocycles II presents comprehensive and up-to-date reviews on selected topics regarding synthetic as well as naturally occurring bioactive heterocycles. The frst chapter, "High Pressure Synthesis of Heterocycles Related to Bio- tive Molecules" by Kiyoshi Matsumoto, presents a unique high-pressure s- thetic methodology in heterocyclic chemistry. Basic principles and fruitful examples for pericyclic reactions, such as Diels-Alder reactions, 1,3-dipolar reactions, and also for ionic reactions, such as S and addition reactions, are N discussed.
Bioactive egg compounds
Hen eggs have exceptional potential as an inexhaustible source for a variety of products with unique properties. These products are valuable to human health and nutrition and can be used as raw materials for diverse purposes in the cosmetics and pharmaceutical industries. Bioactive Egg Compounds presents the latest results and concepts in the biotechnological use of egg compounds. Following an introduction to the different compounds of egg white, yolk and shell, the nutritive value of egg compounds is discussed. Procedures for processing egg compounds to improve their nutritive value are described, including the concept of so-called enriched eggs. Also described is the isolation and application of egg compounds with special properties, such as antibiotic action.
Bioactive composite (cention N) : Sensitivity and microleakage
Recently, a new direct tooth-coloured, bulk-fill, and aesthetic restorative material, Cention N, was developed. This material presents with good mechanical properties and long-term stability due to the crosslinking of methacrylates in the final restoration hence it can be used in load-bearing areas. This graduation project provides an update on the composition and properties of Cention N restorative material, and evaluate the microleakage of Cention-N with Nano-Hybrid composite.
Bioactive and therapeutic dental materials
Special attention has been given to bioactive materials developed to induce cells differentiation/stimulation, hard tissue formation and exert antimicrobial actions. New innovations are necessary to continue to help reinforcing existing technologies and to introduce new paradigms for treating dental disease and restoring teeth seriously compromised by caries lesions via biomimetic and more biological operative approaches. Dental bioactive materials is arguably the latest research area in dentistry and thus the amount of new research is overwhelming. However, in this day and age of evidence based practice it important for this new information to be distilled into a practical and understandable format.
Binary Rare Earth Oxides
The book begins with a brief introduction to binary rare earth oxides, their physical and chemical stabilities, polymorphism, crystal structures and phase transformation and the association with current applications. The book goes on to present the band structure of the oxides using several quantum chemical calculations, which belong to a newly developed area in the binary rare earth oxides. Central to this chapter are the characterizations of electrical, magnetic and optical properties, as well as details of single crystal growth and particle preparation methods that have progressed in recent years. Later chapters concentrate on thermo-chemical properties and trace determination techniques. The final chapter contains a variety of useful applications in various fields such as phosphors, glass abrasives, automotive catalysts, fuel cells, solid electrolytes, sunscreens, iron steels, and biological materials.
BIM for design firms : Data rich architecture at small and medium scales
Expands on Building Information Modeling, showing its applicability to a range of design-oriented projects. It emphasizes the full impact that a data modeling tool has on design processes, systems, and the high level of collaboration required across the design team. It also explains the quantitative analysis opportunities that BIM affords for sustainable design and for balancing competing design agendas, while highlighting the benefits BIM offers to designing in 3D for construction. The book concludes with a deep look at the possible future of BIM and digitally-enhanced design.
Big little hotel : Small hotels designed by architects
This book showcases small hotels, all located in the United States, designed by architects who use light and materials in interesting and intentional ways. The designs also deliberately connect to their local history, context, or land – in many cases all three. Both the architecture and the operations harmonize with the place, whether that is a bustling city, small town, or natural area. Many are new buildings but some are adaptive reuse projects or renovations of historic properties, extending the connectivity of the place into the future.
Big Data Recommender Systems ; Vol.2 : Application Paradigms
Combines experimental and theoretical research on big data recommender systems to help computer scientists develop new concepts and methodologies for complex applications. It includes original scientific contributions in the form of theoretical foundations, comparative analysis, surveys, case studies, techniques and tools. First designed to generate personalized recommendations to users in the 90s, recommender systems apply knowledge discovery techniques to users’ data to suggest information, products, and services that best match their preferences. In recent decades, we have seen an exponential increase in the volumes of data, which has introduced many new challenges. recommender systems. Volume 2 covers a broad range of application paradigms for recommender systems over 22 chapters
Big Data Recommender Systems ; Vol.1 : Algorithms, Architectures, Big Data, Security and Trust
Combines experimental and theoretical research on big data recommender systems to help computer scientists develop new concepts and methodologies for complex applications. It includes original scientific contributions in the form of theoretical foundations, comparative analysis, surveys, case studies, techniques and tools.
Big Data : A Road Map for Successful Digital Marketing
Explores recent trends in the use of big data to predict consumer behavior, strategies to engage online customers, integration of big data with other data sources, and its applications in social media analytics, mobile marketing, search engine optimization and customer relationship management.
Beyond the Worst-Case Analysis of Algorithms
There are no silver bullets in algorithm design, and no single algorithmic idea is powerful and flexible enough to solve every computational problem. Nor are there silver bullets in algorithm analysis, as the most enlightening method for analyzing an algorithm often depends on the problem and the application. However, typical algorithms courses rely almost entirely on a single analysis framework, that of worst-case analysis, wherein an algorithm is assessed by its worst performance on any input of a given size. The purpose of this book is to popularize several alternatives to worst-case analysis and their most notable algorithmic applications, from clustering to linear programming to neural network training. Forty leading researchers have contributed introductions to different facets of this field, emphasizing the most important models and results, many of which can be taught in lectures to beginning graduate students in theoretical computer science and machine learning.
Beyond the limits to growth : New ideas for sustainability from Japan
This book offers an optimistic view of the future and provides a road map for societies to get there. Drawing upon extensive research and many years as a thought leader in environmental and sustainability issues in Japan and internationally, Hiroshi Komiyama analyzes the most pressing challenges to the attainment of sustainability of economically advanced nations and argues forcefully for Japan to lead them out of the present dilemma through active promotion of creative consumer and societal demand. He shows how an active industry–government–academic partnership can provide the environment needed to promote such new creative demand and illustrates its potential through presentation of a Platinum Society Network that was launched on a regional basis in Japan in 2010 to facilitate the solution of common issues through the exchange of information and ideas.
