الصفحة 13
الصفحة 13
Metabolome Analyses : Strategies for Systems Biology
Metabolome Analyses is intended as a follow-up to Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis (Kluwer, 2003). That text offered guidelines to currently available technology, bioinformatics and databases. Evidence was presented showing metabolic profiling as a valuable addition to genomics and proteomics strategies devoted to drug discovery and development. This book focuses on how metabolic profiling is being more comprehensively integrated with the other "omics" technologies. It provides more practical applications of such "panomics" or "Systems Biology" approaches. The expanding use of mass spectrometry as a measurement technology in metabolic profiling is addressed through demonstrated applications. The integration of metabolic profiling and proteomics is probably most developed for plant-based studies, which was not addressed in Volume 1. Other areas related to metabolic profiling continue to show significant development. These include database strategies and an increased acceptance by the pharmaceutical industry of metabolic profiling. Also covered is the use of in silico metabolic networks. Again the focus is primarily on the pharmaceutical industry but the importance of metabolic profiling to studies on human nutrition (a burgeoning area) is discussed.
Messenger RNA therapeutics
Focuses on the fundamentals and applications of messenger RNA (mRNA)-based therapeutics and discusses the strengths and key challenges of this emerging class of drugs. In the past 30 years, extensive research and technological development in many areas have contributed to the emergence of in vitro transcribed mRNA as a therapeutic that has now reached clinical testing. Formulations that protect the mRNA from nucleases and accelerate its cellular uptake, combined with improvements to the mRNA molecules themselves, have been critical advancements for mRNAs to become viable therapeutics. Though once regarded as a serious impediment, the transient nature of mRNA technology is now considered a major advantage in making mRNA therapies safe and, ultimately, a potential game changer in the field of medicine. This new book in the RNA Technologies series provides a state-of-the-art overview on the emerging field of mRNA therapeutics covering essential strategies for formulation, delivery, and application. It also reviews the promising role in cancer immunotherapy, respiratory diseases, and chronic HBV infection and discusses RNA vaccines in light of the current COVID-19 pandemic. mRNA-based approaches have great potential to revolutionize molecular biology, cell biology, biomedical research, and medicine.
Messages security application
The rapid development of communication technology, is bringing many technological conveniences with it and simplifying our lives. On the other hand, it has disadvantages such as hiding the information that is continuously roaming through various communication media resources between senders and receivers and avoid sharing them with third parties. Eliminating these disadvantages via specific security methods and algorithms is related to the discipline called cryptography, which includes information security. Encryption is the process of turning a plaintext to jargon or the method of changing a confidential file to jargon in order to prevent unauthorized persons from gaining access to confidential message. A Message is the transfer of information from the sender to the receiver through a particular medium. Encryption is the most effective process for achieving data security.
MEMS/NEMS : (1) Handbook Techniques and Applications Design Methods, (2) Fabrication Techniques, (3) Manufacturing Methods, (4) Sensors and Actuators, (5) Medical Applications and MOEMS
Micro-Electro Mechanical Systems (MEMS) is the integration of mechanical elements, sensors, actuators, and electronics on a common silicon substrate. While the electronics are fabricated using integrated circuit (IC) process sequences (e.g., CMOS, Bipolar, or BICMOS processes),the micromechanical components are fabricated using compatible micromachining processes that selectively etch away parts of the silicon wafer or add new structural layers to form the mechanical and electromechanical devices. MEMS promises to revolutionize nearly every product category by bringing together silicon-based microelectronics with micromachining technology, thereby, making possible the realization of complete systems-on-a-chip.
Memory B-cells : Methods and protocols
Details in methods to assess memory B cell formation and function in mice and humans. Chapters guide readers through tetramer-based methods to assess antigen-specific memory B cell dynamics in humans and mice in different vaccine, next-generation deep-sequencing, single-cell techniques to assess epigenomic, VDJ landscapes, lymph node aspirates from humans, advanced imaging, murine models to determine memory B cells formation, and bioinformatic techniques and in silico modelling of memory b cell formation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Memories in Wireless Systems
This book is a guide which treats many components used in mobile communications, and in particular focuses on non-volatile memories. It emerges following the conducting line of the non-volatile memory in the wireless system: On the one hand it develops the foundations of the interdisciplinary issues needed for design analysis and testing of the system. On the other hand it deals with many of the problems appearing when the systems are realized in industrial production. These cover the difficulties from the mobile system to the different types of non-volatile memories.
Medicinal plants : From farm to pharmacy
Discuss current research on medicinal plants that connects traditionally accumulated botanical wisdom with current bioprospecting trends and (pre-clinical studies Provide an account of recent research activities on select medicinal plants from various phytogeographical regions all over the world Cater to the interest of a wide range of readers including lay enthusiasts, traditional practitioners as well as research and clinical professionals
Medicinal plants : Bioprospecting and pharmacognosy
Touches on a diverse selection of topics related to medicinal plants. Chapters look at the use of medicinal plants in healthcare and disease management, such as to treat inflammation, anti-hyperglycemia, and obesity and as immunity boosters. The authors also address the conservation, maintenance, and sustainable utilization of medicinal plants along with postharvest management issues. Topics include consumption, supply chain, marketing, trade, and future directions of research. Some specific plants discussed include fennel, basil, clove, ginger, lavender, turmeric, ginsing, and asparagus in connection with their various therapeutic properties, including anti-rheumatic, anti-asthmatic, anti-diabetic, carminative, diuretic, fever-reducing, and hypotensive. Medicinal Plants: Bioprospecting and Pharmacognosy will prove informative for scientists and researchers in medicinal plants as well as for faculty and students, pharmaceutical researchers, and others.
Medicinal compounds in modern healthcare : From tradition to innovation
Reviews the evolution, development, and application of medicinal compounds, beginning with their historical context and advancing to modern innovations. The book describes the therapeutic potential of bioactive compounds from microorganisms, the role of antioxidants and anti-inflammatory agents in managing chronic diseases, and the use of small molecules in pain management and mental healthcare. It further explores immunomodulatory compounds, epigenetic modifiers, and the latest advancements in drug development, including integrative medicine approaches and the applications of nanotechnology in traditional medicine. Additionally, the book addresses the use of immunomodulatory agents like methotrexate and paclitaxel in cancer treatment, regulatory considerations for ensuring safety and efficacy in medicinal compounds, and the growing field of nutraceuticals. Towards the end, the book covers the extraction, profiling, and ADMET evaluation of medicinal compounds, intellectual property challenges, and the significance of traditional medicine in modern healthcare.
Medical Reprints: 3D ed.
3D printing or additive manufacturing is a novel method of manufacturing parts directly from a digital model by using layer by layer material build-up approaches. This discovery is predicted to have the greatest impact on the future industries. Additive manufacturing has numerous applications in different areas including healthcare. Applications encompass many medical fields such as dentistry, surgery, and medical devices as well as the pharmaceutical field. Due to transplant donor deficiencies, ‘bioprinting’ has been invented to print biocompatible organs. Adding ‘time’ as a 4th dimension, 4D printing uses ‘smart materials’ to initiate the ‘smart drugs’ era.
Medical laboratory technology procedure : manual for routine diagnostic tests ; Vol.3
Salient features Predominantly tailored to the requirements of laboratories with limited facilities in developing countries, this manual: Introduces methods and procedures for producing reliable laboratory findings Describes all tests in a step-by-step manner with guidelines to avoid errors and hazards Explains care and use of laboratory equipment and preparation of reagents Details Zika and Chikungunya virus infections Highlights the clinical significance of laboratory findings Provides illustrations for easy comprehension The fourth edition features a number of important additions containing the latest topics relevant to the subject
Medical biotechnology, biopharmaceutics, forensic : science and bioinformatics
Covers a range of topics on exploiting Nigeria’s mega biodiversity for food security and health; DNA forensic science and its applications; medical biotechnology and biopharmaceutics; medicinal and underutilized plants; impact and mitigation of antibiotic resistance; bioinformatics applications; medical insect biotechnology; etc. The book will be useful reference material for the scientists and researchers working in the fields of nutraceuticals, molecular diagnostics and DNA forensics, biopharmaceuticals and medical biotechnology, nanotechnology, antimicrobials from indigenous plant species, bioinformatics, etc.
Medial Representations : Mathematics, Algorithms and Applications
The last half century has seen the development of many biological or physical theories that have explicitly or implicitly involved medial descriptions of objects and other spatial entities in our world. Simultaneously mathematicians have studied the properties of these skeletal descriptions of shape, and, stimulated by the many areas where medial models are useful, computer scientists and engineers have developed numerous algorithms for computing and using these models. We bring this knowledge and experience together into this book in order to make medial technology more widely understood and used.
Media Theory : Interdisciplinary Applied Mathematics
The focus of this book is a mathematical structure modeling a physical or biological system that can be in any of a number of `states.' Each state is characterized by a set of binary features, and differs from some other neighbor state or states by just one of those feature. A simple example of a `state’ is a partial solution of a jigsaw puzzle, which can be transformed into another partial solution or into the final solution just by adding or removing a single adjoining piece. The evolution of such a system over time is considered. Such a structure is analyzed from algebraic and probabilistic (stochastic) standpoints.
Mechanochemistry in Nanoscience and Minerals Engineering
Mechanochemistry as a branch of solid state chemistry enquires into processes which proceed in solids due to the application of mechanical energy. This provides a thorough, up to date overview of mechanochemistry of solids and minerals. Applications of mechanochemistry in nanoscience with special impact on nanogeoscience are described. Selected advanced identification methods, most frequently applied in nanoscience, are described as well as the advantage of mechanochemical approach in minerals engineering. Examples of industrial applications are given. Mechanochemical technology is being applied in many industrial fields: powder metallurgy (synthesis of nanometals, alloys and nanocompounds), building industry (activation of cements), chemical industry (solid waste treatment, catalyst synthesis, coal ashes utilization), minerals engineering (ore enrichment, enhancement of processes of extractive metallurgy), agriculture industry (solubility increase of fertilizers), and pharmaceutical industry (improvement of solubility and bioavailability of drugs).
Meat Biotechnology
The main goal of this book is to provide the reader with the recent developments in biotechnology and their applications in the meat processing chain. To achieve this goal, the book is divided into four parts. The first part deals with the use of modern biotechnology applied to farm animals. The second part focuses on the recent biotechnological developments in starter cultures for better meat fermentation. The third part discusses current approaches to improve the quality and nutritional properties of meats. The final part presents the latest advances in protection against foodborne pathogens, and other recent trends in the field. Written by distinguished international contributors, this book brings together the advances in such varied and different biotechnological topics
Measuring the Business Value of Cloud Computing
The importance of demonstrating the value achieved from IT investments is long established in the Computer Science (CS) and Information Systems (IS) literature. However, emerging technologies such as the ever-changing complex area of cloud computing present new challenges and opportunities for demonstrating how IT investments lead to business value.
Measurement, Control, and Communication Using IEEE 1588
IEEE 1588, published in November 2002, is a technology new to the engineering community expanding the performance capabilities of Ethernet networks so that they become relevant for measurement and control; this monograph embodies the first unified treatment of the associated technology, standards and applications. Readers unfamiliar with IEEE 1588 will gain understanding of the context of the technology it represents and, from three chapters of case studies, its role in a variety of application settings.
Measurement Uncertainties in Science and Technology
At the turn of the 19th century, Carl Friedrich Gauß founded error calculus by predicting the then unknown position of the planet Ceres. Ever since, error calculus has occupied a place at the heart of science. In this book, Grabe illustrates the breakdown of traditional error calculus in the face of modern measurement techniques. Revising Gauß’ error calculus ab initio, he treats random and unknown systematic errors on an equal footing from the outset. Furthermore, Grabe also proposes what may be called well defined measuring conditions, a prerequisite for defining confidence intervals that are consistent with basic statistical concepts. The resulting measurement uncertainties are as robust and reliable as required by modern-day science, engineering and technology.
MDCT : From Protocols to Practice
MDCT: From Protocols to Practice tackles contemporary and topical issues in MDCT technology and applications. This volume offers new content as well as revised chapters from the previous volume.
