الصفحة 13
الصفحة 13
Collagen : Primer in Structure, Processing and Assembly
This volume of Topics in Current Chemistry is an attempt to update and compile the biochemical, molecular knowledge of the still growing family of collagenous proteins. Its intention is to provide a comprehensive summary of all mechanisms known to be involved in synthesis, processing and deposition of collagen molecules, all of which are apparently shared by any known collagen type as part of a common biosynthetic route. From the intracellular initiation of protein translation to the extracellular deposition of mature molecules into the scaffold of the preformed tissue texture, collagen biosynthesis exhibits a profile of mechanisms absolutely unique when compared to other proteins
CO-ENZYME Q10
Coenzyme Q10 (CoQ10) is a fat-soluble compound that is synthesized by the body and can be obtained from the diet. Co-Q10 plays a central role in mitochondrial oxidative phosphorylation and the production of adenosine triphosphate (ATP). It also functions as an antioxidant in cell membranes and lipoproteins. Endogenous synthesis and dietary intake provide sufficient C0- Q10 to prevent deficiency in healthy people, although coenzyme Q10 concentrations in tissues decline with age. Oral supplementation of coenzyme Q10 increases coenzyme Q10 concentrations in plasma and lipoproteins. Oral high-dose co- Q10 is usually effective to treat mitochondrial disorders that are caused by mutations in coenzyme Q10 biosynthetic genes.
Coding, shaping, making : experiments in form and form-making
Combines inspiration from architecture, mathematics, biology, chemistry, physics and computation to look towards the future of architecture, design and art. It presents ongoing experiments in the search for fundamental principles of form and form-making in nature so that we can better inform our own built environment.
Coastal Fluxes in the Anthropocene : The Land-Ocean Interactions in the Coastal Zone Project of the International Geosphere-Biosphere Programme
In global coastal zones, the major fabric of goods and services for human welfare as well as global changes are extraordinarily visible. They are shaped by natural Earth systems processes on a planetary scale, which are reflected in a continuously adapting coastal environment. Now, in the "Anthropocene", human society is a greater catalyst for change - impacting and modifying coastal processes. This book synthesizes knowledge on coastal and riverine material fluxes, biogeochemical processes and indications of change, and the human influence, before looking at future research and management needs. It is a milestone rather than a destination on the journey which continues under the new International Geosphere-Biosphere Programme (IGBP), the International Human Dimensions Programme on Global Environmental Change (IHDP) and the LOICZ II (Land-Ocean Interactions in the Coastal Zone) Project.
Co- and post-translational modifications of therapeutic antibodies and proteins
A Comprehensive Guide to Crucial Attributes of Therapeutic Proteins in Biological Pharmaceuticals With this book, Dr. Raju offers a valuable resource for professionals involved in research and development of biopharmaceutical and biosimilar drugs. This is a highly relevant work, as medical practitioners have increasingly turned to biopharmaceutical medicines in their search for safe and reliable treatments for
CMOS Biotechnology
"CMOS Biotechnology reviews the recent research and developments joining CMOS technology with biology. Written by leading researchers these chapters delve into four areas including: Microfluidics for electrical engineers / CMOS Actuators CMOS Electrical Sensors CMOS Optical Sensors Bioanalytical instruments have been miniaturized on ICs to study various biophenomena or to actuate biosystems. These bio-lab-on-IC systems utilize the IC to facilitate faster, repeatable, and standardized biological experiments at low cost with a small volume of biological sample. CMOS Biotechnology will interest electrical engineers, bioengineers, biophysicists as well as researchers in MEMS, bioMEMS, microelectronics, microfluidics, and circuits and systems."
Mathematical Modelling of Biosystems
This volume is an interdisciplinary book, which introduces, in a very readable way, state of the art research in the fundamental topics of mathematical modelling of Biosystems. These topics include: the study of Biological Growth and its mechanisms, the coupling of pattern to form via theorems of Differential Geometry, the human immunodeficiency virus dynamics, the inverse folding problem and the possibility of analysing true protein backbone flexibility, the Biclustering techniques for the organization of microarray data, the analytical approach to the modelling of biomolecular structure via Steiner trees, the action of biocides on resistance mechanisms of mutated and phenotypic bacteria strains, a description of the fundamental processes for the distribution and abundances of species towards a unified theory of Ecology, and a special introduction to Protein Physics aiming to explain the all-or-none first order phase transitions from native to denatured states.
Mathematical Formulas for Economists
This collection of formulas constitutes a compendium of mathematics for eco nomics and business. It contains the most important formulas, statements and algorithms in this significant subfield of modern mathematics and addresses primarily students of economics or business at universities, colleges and trade schools. But people dealing with practical or applied problems will also find this collection to be an efiicient and easy-to-use work of reference. First the book treats mathematical symbols and constants, sets and state ments, number systems and their arithmetic as well as fundamentals of com binatorics. The chapter on sequences and series is followed by mathematics of finance, the representation of functions of one and several independent vari ables, their differential and integral calculus and by differential and difference equations. In each case special emphasis is placed on applications and models in economics. The chapter on linear algebra deals with matrices, vectors, determinants and systems of linear equations. This is followed by the representation of struc tures and algorithms of linear programming. Finally, the reader finds formu las on descriptive statistics (data analysis, ratios, inventory and time series analysis), on probability theory (events, probabilities, random variables and distributions) and on inductive statistics (point and interval estimates, tests). Some important tables complete the work.
Master Dentistry ; Vol.1 : Oral and Maxillofacial Surgery, Radiology, Pathology and Oral Medicine
Provides a comprehensive overview of the oral and maxillofacial subjects in dentistry that students will need in order to pass their final exams. This invaluable adjunct to exam preparation provides a practical synthesis of core information, reflecting real-life case scenarios. Information is structured to enhance understanding and clinical decision making, and a variety of self-assessment methods prepare students for success. Comprehensively updated, the book covers a range of essential topics in the field of contemporary oral and maxillofacial subjects, including surgical flap design, state-of-the-art surgical techniques, zygomatic implants, molecular pathology, current imaging applications and pain management. The text is integrated and evidence based throughout. Covers oral and maxillofacial surgery, radiology, pathology and oral medicine subjects Brand new chapter on facial skin broadens diagnostic ability Range of self-assessment tasks to support learning Aligns to dental school curricula globally Concise and easy to follow Designed to support recall for examination purposes Practical guidance on examination preparation and skills Perfect for BDS exam preparation and candidates taking the MFDS, MJDF, ORE or other post-graduate exams
Martens and Fishers (Martes) in human-altered environments : An international perspective
Examines the conditions where humans and martens are compatible and incompatible, and promotes land use practices that allow Martes to be representatively distributed and viable. All Martes have been documented to use forested habitats and 6 species (excluding the stone marten) are generally considered to require complex mid- to late-successional forests throughout much of their geographic ranges. All species in the genus require complex horizontal and vertical structure to provide escape cover protection from predators, habitat for their prey, access to food resources, and protection from the elements. Martens and the fisher have high metabolic rates, have large spatial requirements, have high surface area to volume ratios for animals that often inhabit high latitudes, and often require among the largest home range areas per unit body weight of any group of mammals. Resulting from these unique life history characteristics, this genus is particularly sensitive to human influences on their habitats, including habitat loss, stand-scale simplification of forest structure via some forms of logging, and landscape-scale effects of habitat fragmentation. Given their strong associations with structural complexity in forests, martens and the fisher are often considered as useful barometers of forest health and have been used as ecological indicators, flagship, and umbrella species in different parts of the world. Thus, efforts to successfully conserve and manage martens and fishers are associated with the ecological fates of other forest dependent species and can greatly influence ecosystem integrity within forests that are increasingly shared among wildlife and humans.We have made great strides in our fundamental understanding of how animals with these unique life history traits perceive and utilize habitats, respond to habitat change, and how their populations function and perform under different forms of human management and mismanagement.
Marketing Analytics : A Practical Guide to Improving Consumer Insights Using Data Techniques
Simplifies intimidating data, segmentation and predictive analytics tools for everyday use in business, using real-world marketing problems to apply to a range of practical scenarios / Provides accessibility and insightful application of techniques regardless of experience level
Managing Socio-ecological Production Landscapes and Seascapes for Sustainable Communities in Asia : Mapping and Navigating Stakeholders, Policy and Action
This book presents up-to-date analyses of community-based approaches to sustainable resource management of SEPLS (socio-ecological production landscapes and seascapes) in areas where a harmonious relationship between the natural environment and the people who inhabit it is essential to ensure community and environmental well-being as well as to build resilience in the ecosystems that support this well-being.
Making with data : Physical design and craft in a data-driven world
Making with Data: Physical Design and Craft in a Data-Driven World provides a snapshot of the diverse practices contemporary creators are using to produce objects, spaces, and experiences imbued with data. Across 25+ beautifully-illustrated chapters, international artists, designers, and scientists each explain the process of creating a specific data-driven piece—illustrating their practice with candid sketches, photos, and design artifacts from their own studios. Featuring influential voices in computer science, data science, graphic design, art, craft, and architecture, Making with Data is accessible and inspiring for enthusiasts and experts alike.
Machine learning in healthcare : Fundamentals and recent applications
Discusses how to build various ML algorithms and how they can be applied to improve healthcare systems. Healthcare applications of AI are innumerable: medical data analysis, early detection and diagnosis of disease, providing objective-based evidence to reduce human errors, curtailing inter- and intra-observer errors, risk identification and interventions for healthcare management, real-time health monitoring, assisting clinicians and patients for selecting appropriate medications, and evaluating drug responses. Extensive demonstrations and discussion on the various principles of machine learning and its application in healthcare is provided, along with solved examples and exercises.
Machine learning for biomedical application
Biomedicine is a multidisciplinary branch of medical science that consists of many scientific disciplines, e.g., biology, biotechnology, bioinformatics, and genetics; moreover, it covers various medical specialties. In recent years, this field of science has developed rapidly. This means that a large amount of data has been generated, due to (among other reasons) the processing, analysis, and recognition of a wide range of biomedical signals and images obtained through increasingly advanced medical imaging devices. The analysis of these data requires the use of advanced IT methods, which include those related to the use of artificial intelligence, and in particular machine learning. It is a summary of the Special Issue “Machine Learning for Biomedical Application”, briefly outlining selected applications of machine learning in the processing, analysis, and recognition of biomedical data, mostly regarding biosignals and medical images.
Machine learning and deep learning in medical data analytics and healthcare applications
Introduces and explores a variety of schemes designed to empower, enhance, and represent multi-institutional and multi-disciplinary machine learning (ML) and deep learning (DL) research in healthcare paradigms. Serving as a unique compendium of existing and emerging ML/DL paradigms for the healthcare sector, this book demonstrates the depth, breadth, complexity, and diversity of this multi-disciplinary area. It provides a comprehensive overview of ML/DL algorithms and explores the related use cases in enterprises such as computer-aided medical diagnostics, drug discovery and development, medical imaging, automation, robotic surgery, electronic smart records creation, outbreak prediction, medical image analysis, and radiation treatments.
Machine Ethics : From Machine Morals to the Machinery of Morality
Offers the first systematic guide to machine ethics, bridging between computer science, social sciences and philosophy. Based on a dialogue between an AI scientist and a novelist philosopher, the book discusses important findings on which moral values machines can be taught and how. In turn, it investigates what kind of artificial intelligence (AI) people do actually want.
Mac OS X Leopard : Beyond the Manual
Good computer books make assumptions about the reader: what they do and don't know when they pick up the book, and what they want to know when they put it down. For each reader this could be very different; therefore, a book that suits one person may not be the best for another. Mac OS X Leopard: Beyond the Manual makes some assumptions too, ones that tend to differ from other Mac OS X books. First of all, we assume that you have used a computer in that past: that you know how to use a mouse and you know the proper place to stick a DVD to get it to play in your computer. We won't be showing you these things. (We will, however, demonstrate to our Mac converts how to “right click” on a trackpad with only one button!).
Lung biology and pathophysiology
The lungs are the organ for gas exchange between the body and the external environment. Dysfunction of upper airway epithelium and smooth muscle cells leads to pathogenesis of asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, and other conditions, resulting in airway inflammation and narrowing. Injury to alveolar epithelium and endothelium causes influx of neutrophil and protein-rich fluid from circulation, resulting in edema and disruption of gas exchange. In addition to lung structural cells, immune cells, including alveolar macrophages and lymphocytes play critical roles in the maintenance of lung function. This book contributes to the understanding homeostasis of lung cells in the physiological and pathological conditions critical to the development of novel therapeutics.
Logging in Java with the JDK 1.4 Logging API and Apache log4j
In development scenarios where things can't be run in a debugger, or when you run the risk of masking the problem, logs are the greatest source of information about running a program. Pro Apache Log4j, Second Edition provides best practices guidelines and comprehensive coverage of the most recent release. Step by step, the book explains core concepts, from basic to advanced. Code samples are in Java and include guidelines for different application-specific needs. You'll also learn how to extend the API to write custom components and best practices for using the feature-rich log4j API. This book concludes with enterprise Java applications using log4j with JSP and J2EE.
