الصفحة 12
الصفحة 12
Quasispecies : Concept and Implications for Virology
Continuous genetic variation and selection of virus subpopulations in the course of RNA virus replications are intimately related to viral disease mechanisms. The central topics of this volume are the origins of the quasispecies concept, and the implications of quasispecies dynamics for viral populations.
Quantum dots : A doorway to nanoscale pPhysics
Devoted to an introduction to some of these fascinating aspects, addressing in particular graduate students and young researchers in the field. In the first lecture by R. Shankar the general theoretical aspects of Fermi liquids are addressed, in particular the renormalization group approach. This is then aptly applied to large quantum dots. A completely different approach is encountered in the second contribution by J.M. Elzerman et al. in that it is a thorough experimental expose of what can be done or expected in the study of small quantum dots. Here the emphasis lies on the electron spin to be used as a qubit. In the third lecture series, by M. Pustilnik and Leonid I. Glazman mechanisms of low-temperature electronic transport through a quantum dot -- weakly coupled to two conducting leads -- are reviewed. The fourth series of lectures by C.W.J. Beenakker deals with a very interesting aspect of nanophysics: a peculiar property of superconducting mirrors discovered by Andreev about forty years ago and still a challenge to experimental physicists.
Quality of Service in Optical Burst Switched Networks
Quality of Service in Optical Burst Switched Networks is a broad review and reference for researchers and professionals of Quality of Service (QoS) support in Optical Burst Switching (OBS) networks. The authors start with an overview of OBS architecture, then categorize and discuss existing QoS support in OBS including relative and absolute models, mechanisms for supporting multiple traffic classes, edge-to-edge provisioning, and other non-mainstream mechanisms. Optical networking professionals will find the literature review as an up-to-date coverage of topics which is both timely and helpful.
Quadratic Mappings and Clifford Algebras
After a classical presentation of quadratic mappings and Clifford algebras over arbitrary rings (commutative, associative, with unit), other topics involve more original methods: interior multiplications allow an effective treatment of deformations of Clifford algebras; the relations between automorphisms of quadratic forms and Clifford algebras are based on the concept of the Lipschitz monoid, from which several groups are derived; and the Cartan-Chevalley theory of hyperbolic spaces becomes much more general, precise and effective.
PTSD : Brain Mechanisms and Clinical Implications
This book breaks new ground by offering neuroscientific insights into PTSD and their implications for diagnosis, prevention, and treatment. The recent explosion of biological investigation into this distressing and disabling condition has been led by this volume’s authors, who range from skilled basic scientists to experienced diagnosticians and therapists. Their contributions epitomize state-of-the-art, translational research in clinical neuroscience, and will prove to be an invaluable source of reference for practitioners and researchers in this field.
Psychrophiles : From Biodiversity to Biotechnology
Of the current studies on extremophiles, approximately 30,000 articles by the year 2007, almost two-thirds have been performed on organisms adapted to outstanding temperatures, but much more attention has been paid to thermophiles than to psychrophiles. However, over the past 10 years, scientific publications on cold-adapted microorganisms have increased by a factor of ten. These microorganisms have evolved a number of strategies to thrive success-fully in cold habitats where they play key roles in nutrient cycling, such as nitrogen fixation, nitrification and denitrification, photosynthesis, sulfur oxidation and reduction, methanogenesis, and transformation of organic compounds. This book is focused on psychrophiles and describes, at the edge of knowledge, representative groups of cold-adapted microorganisms as well as the habitats in which they live and their strategies to cope with the cold.
Psychopharmacogenetics
In this book, the basic and advanced knowledge on psychiatric disorders will be provided for non-clinicians: What is schizophrenia? What are the risk factors? What are the core symptoms? How is it treated? What are the efficacy and side effects of the available treatments and their mechanisms? Are there already some psychopharmacogenetic data useful in clinical practice?
Psoriasis and Psoriatic Arthritis : An Integrated Approach
In the past decade it has become increasingly clear that psoriatic disease, both of the skin and joints, can be a significant diagnostic and therapeutic challenge for the physician and a debilitating illness for the patient. At the same time, advances in genetics and immunology have increased our understanding of the pathophysiology of psoriasis and psoriatic arthritis. This text contains a comprehensive discussion by an international group of experts in psoriatic disease of the pathomechanisms, genetics, diagnosis, and treatment of psoriasis and psoriatic arthritis. The information is presented in parallel in order to emphasize the similarities and differences between these two diseases that so commonly occur together. We believe that this approach will make this text an important resource for all practitioners who treat patients with psoriasis and psoriatic arthritis.
Pseudomonas syringae Pathovars and Related Pathogens : Identification, Epidemiology and Genomics
This book reports on recent advances on: (1) new methods and approaches for specific and sensitive detection and identification of Pseudomonas syringae and Ralstonia solanacearum; (2) ecology and epidemiology bases of Pseudomonas syringae that enable the development of management strategies; (3) pathogenesis and determinant of pathogenicity, and in particular, mechanisms involved in virulence and virulence gene expression; (4) evolution and diversity of the pseudomonads through multilocus sequence typing (MLST) analysis; (5) determination of pathogens associated with new and emerging diseases; (6) effect of global warming on increase and emergence of new bacterial diseases."
Protein Misfolding, Aggregation and Conformational Diseases ; Part B : Molecular Mechanisms of Conformational Diseases
This volume summarizes recent achievements in the understanding of the molecular mechanisms of conformational diseases. Research indicates that these mechanisms are highly diverse and range from the altered protein structure leading to the enhanced propensity for aggregation/deposition or the impaired functions and ending with changes in supra-molecular structures or posttranslational modification.
Promising Antimicrobials from Natural Products
Present a comprehensive outlook of current research in the field of natural antimicrobials. It discusses the antimicrobial activity of medicinal plants, beehives, and mushrooms with a global coverage of antimicrobial agents from rich forests of Brazil (Amazon), North-Eastern forests of Peru, Argentina, Colombia, India, Bangladesh, Nepal, Middle East, Turkey, Croatia, Greece, Germany and Russia.
Promises and challenges of regenerative medicine
The attitude to the possibility of regeneration in mammals has changed in recent years to one of cautious optimism that the endogenous mechanisms can be exploited for the medical armentarium. In this volume leading experts discuss the molecular, in vivo and clinical aspects of the use of stem cells in various disease contexts. With the current excitement in the research and clinical communities over the potential of regenerative medicine it is hoped that novel therapies will emerge that target intractable degenerative diseases. The book contains accounts of the latest advances in stem cell biology from the foremost researchers in the field. It discusses the analysis and use of stem cells in basic biology but also their application in clinical practice and is therefore unique in combining basic and applied approaches.
Progressive collapse resilience of concrete structures : Mechanisms, simulations and experiments
The book introduces the comprehensive analysis methodology regarding progressive collapse, and the critical issues may happen in concrete structures. Main topics include: the influential parameters of the development of the main load-resisting mechanisms; the dynamic effects with sudden column removal scenarios; the contribution of non-structural components to improve the resilience of concrete structures; uncertainties in progressive collapse analysis.
Progress in the Chemistry of Organic Natural Products 109
This volume comprises three reviews. The first describes isolation, structure determination, syntheses, and biochemistry of the low molecular weight compounds of the secretion of exocrine glands of termies with emphasis to pheromones and defensive compounds. The second review describes recent studies on isolation and structure elucidation of bioactive compounds involved in the life cycle and determination of the molecular mechanisms of the developmental events observed in higher plants. The third contribution reports on the current body of knowledge of African propolis, with a particular emphasis on its chemistry and biological activity.
Progress in Scale Modeling : Summary of the 1st International Symposium on Scale Modeling (ISSM I in 1988) and Selected Papers from Subsequent Symposia (ISSM II in 1997 through ISSM V in 2006)
A selection of seminal papers given at the past International Symposia on Scale Modeling (ISSM). Scale modeling is a simplifying and clarifying tool used by scientists and engineers in many disciplines to help them grasp essential or salient aspects of bewilderingly complex systems, mechanisms and phenomena -- In addition, scale modeling is an approach that offers engineers and designers a new point of view, liberating creative and innovative ideas and solutions. Scale modeling is employed to study weather systems, diffusion of pollution in air or water, chemical process in 3-D turbulent flow, multiphase combustion, flame propagation, biological systems, behavior of materials at nano- and micro- scales and so on.
Progress in Galois Theory ; Proceedings of John Thompson's 70th Birthday Conference
A recent trend in the field of Galois theory is to tie the previous theory of curve coverings (mostly of the Riemann sphere) and Hurwitz spaces (moduli spaces for such covers) with the theory of algebraic curves and their moduli spaces. A general survey of this is given in the article by Voelklein. Further exemplifications come in the articles of Guralnick on automorphisms of modular curves in positive characteristic, of Zarhin on the Galois module structure of the 2-division points of hyperelliptic curves and of Krishnamoorthy, Shashka and Voelklein on invariants of genus 2 curves.
Programming languages and systems
Notions of computation can be modelled by monads. Algebraic effects offer a characterization of monads in terms of algebraic operations and equational axioms, where operations are basic programming features, such as reading or updating the state, and axioms specify observably equivalent expressions. However, many useful programming features depend on additional mechanisms such as delimited scopes or dynamically allocated resources. Such mechanisms can be supported via extensions to algebraic effects including scoped effects and parameterized algebraic theories.
Programmed Cell Death in Protozoa
Under the name of programmed cell death (PCD) are included diverse molecular mechanism of cell suicide which play an essential role in the development of multicellular organisms. The best known PCD mechanism in multicellular organisms is called apoptosis. However, recent studies indicate that PCD is also present in protozoa and unicellular eukaryotes. The eleven chapters of this book give the reader a comprehensive update of the progress in the understanding of the mechanisms of PCD in protozoa. The chapters have been written by experts in this field of research and are arranged following an evolutionary point of view starting with PCD in protists and ending with PCD in ciliated protozoa.
Programmed Cell Death in Cancer Progression and Therapy
With this book, we give a comprehensive overview of the mechanisms that are involved in mediating and regulating PCD in cancer. We also provide a detailed indication of the utility of PCD in cancer therapy. This book will be a valuable resource for researchers investigating the role of PCD in cancer and other diseases, researchers investigating the molecular mechanism of chemotherapeutic agents and drug-resistance in cancer and for physicians using chemotherapeutic agents.
Probiotics for better future
Probiotics are defined as live microorganisms, which when administered in adequate amounts, confer a health benefit on the host. Health benefits have mainly been demonstrated for specific probiotic strains of the following genera: Lactobacillus, Bifidobacterium, Saccharomyces, Enterococcus, Streptoc occus, Pediococcus, Leuconostoc, Bacillus, Escherichia coli. The human microbiota is getting a lot of attention today and research has already demonstrated that alteration of this microbiota may have far-reaching consequences. One of the possible routes for correcting dysbiosis...
