الصفحة 116
الصفحة 116
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Leibniz : What Kind of Rationalist?

The chapters of the book are the result of intense discussion in the course of an international conference focused on the title question of this book, and were selected in view of their contribution to this topic. They are clustered in thematically organized parts. No effort has been made to hide the controversies underlying the different interpretations of Leibniz’s “rationalism” – in each particular domain and as a whole. On the contrary, the editor firmly believes that only through a variety of conflicting interpretive perspectives can the multi-faceted nature of an oeuvre of such a magnitude and variety as Leibniz’s be brought to light and understood as it deserves.

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Lectures on the Automorphism Groups of Kobayashi-Hyperbolic Manifolds

Presents a coherent exposition of recent results on complete characterization of Kobayashi-hyperbolic manifolds with high-dimensional groups of holomorphic automorphisms. These classification results can be viewed as complex-geometric analogues of those known for Riemannian manifolds with high-dimensional isotropy groups, that were extensively studied in the 1950s-70s. The common feature of the Kobayashi-hyperbolic and Riemannian cases is the properness of the actions of the holomorphic automorphism group and the isometry group on respective manifolds.

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Lectures on Symplectic Geometry

Provides a fast introduction to symplectic geometry for graduate students with some knowledge of differential geometry, de Rham theory and classical Lie groups. This text addresses symplectomorphisms, local forms, contact manifolds, compatible almost complex structures, Kaehler manifolds, hamiltonian mechanics, moment maps, symplectic reduction and symplectic toric manifolds. It contains guided problems, called homework, designed to complement the exposition or extend the reader's understanding.

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Lectures on Probability Theory and Statistics : Ecole d'Eté de Probabilités de Saint-Flour XXXIII - 2003

Contains two of the three lectures that were given at the 33rd Probability Summer School in Saint-Flour (July 6-23, 2003). Amir Dembo’s course is devoted to recent studies of the fractal nature of random sets, focusing on some fine properties of the sample path of random walk and Brownian motion. In particular, the cover time for Markov chains, the dimension of discrete limsup random fractals, the multi-scale truncated second moment and the Ciesielski-Taylor identities are explored. Tadahisa Funaki’s course reviews recent developments of the mathematical theory on stochastic interface models, mostly on the so-called nabla varphi interface model. The results are formulated as classical limit theorems in probability theory, and the text serves with good applications of basic probability techniques.

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Lectures on Algebraic Geometry I : Sheaves, Cohomology of Sheaves, and Applications to Riemann Surfaces

This book and the following second volume is an introduction into modern algebraic geometry. In the first volume the methods of homological algebra, theory of sheaves, and sheaf cohomology are developed. These methods are indispensable for modern algebraic geometry, but they are also fundamental for other branches of mathematics and of great interest in their own.In the last chapter of volume I these concepts are applied to the theory of compact Riemann surfaces. In this chapter the author makes clear how influential the ideas of Abel, Riemann and Jacobi were and that many of the modern methods have been anticipated by them.

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Lectures on Advances in Combinatorics

The main focus of these lectures is basis extremal problems and inequalities – two sides of the same coin. Additionally they prepare well for approaches and methods useful and applicable in a broader mathematical context. Highlights of the book include a solution to the famous 4m-conjecture of Erdös/Ko/Rado 1938, one of the oldest problems in combinatorial extremal theory, an answer to a question of Erdös (1962) in combinatorial number theory "What is the maximal cardinality of a set of numbers smaller than n with no k+1 of its members pair wise relatively prime?", and the discovery that the AD-inequality implies more general and sharper number theoretical inequalities than for instance Behrend's inequality.

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Lecture Notes on General Medicine for Dental Practice : A System based Approach with Dental Management Considerations

Offers a system based approach covering a broad range of topics in general medicine for dental practice. The book includes chapters on history taking and patient interview, general physical examination, system specific examination, common health related complaints, systemic infections, and diseases of the gastrointestinal, cardiovascular, respiratory, neurological, immunological, renal, endocrinal, dermatological and musculoskeletal systems. Nutritional disorders, psychiatric disorders, the female patient with menstrual, menopause and pregnancy related disorders, dental management of patients taking medications for systemic conditions and medical emergencies in dental practice have also been discussed in some detail.

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Learning to Diagnose with Simulations : Examples from Teacher Education and Medical Education

Presents 8 novel approaches to measure and improve diagnostic competences with simulation. The book compares the effects of interventions on these diagnostic competences in both teacher and medical education. It includes analyses showing that important aspects of diagnostic competences and effects of instructional interventions aiming to facilitate them are comparable for teachers and doctors.

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Learning from nature how to design new implantable biomaterialsis : From biomineralization fundamentals to biomimetic materials and processing routes ; Proceedings of the NATO Advanced Study Institute, held in Alvor, Algarve, Portugal, 13-24 October 2003

The demands upon the material properties largely depend on the site of application and the function it has to restore. Ideally, a replacement material should mimic the living tissue from a mechanical, chemical, biological and functional point of view.

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Learning Classifier Systems ; 10th International Workshop, IWLCS 2006, Seattle, MA, USA, July 8, 2006 and 11th International Workshop, IWLCS 2007, London, UK, July 8, 2007, Revised Selected Papers

Constitutes the thoroughly refereed joint post-conference proceedings of two consecutive International Workshops on Learning Classifier Systems that took place in Seattle, WA, USA in July 2006, and in London, UK, in July 2007 - all hosted by the Genetic and Evolutionary Computation Conference, GECCO.The 14 revised full papers presented were carefully reviewed and selected from the workshop contributions. The papers are organized in topical sections on knowledge representation, analysis of the system, mechanisms, new directions, as well as applications.

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Learning and Intelligent Optimization ; 2nd International Conference, LION 2007 II, Trento, Italy, December 8-12, 2007. Selected Papers

The papers cover current issues of machine learning, artificial intelligence, mathematical programming and algorithms for hard optimization problems and are organized in topical sections on improving optimization through learning, variable neighborhood search, insect colony optimization, applications, new paradigms, cliques, stochastic optimization, combinatorial optimization, fitness and landscapes, and particle swarm optimization.

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Leading Pharmaceutical Innovation : Trends and Drivers for Growth in the Pharmaceutical Industry

Pharmaceutical giants have doubled their investments in drug development in the past decade only to see new drug approvals remain constant. This book investigates and highlights a set of proactive strategies aimed at generating sustainable competitive advantage based on value-generating business practices. We focus on three sources of pharmaceutical innovation: new management methods in the drug development pipeline, new technologies as enablers for cutting-edge R&D, and new forms of cooperation and internationalization, such as open innovation in the early phases of R&D. Our findings are illustrated by cases from Europe, the US, and Asia.

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Lead-Free Electronic Solders : A Special Issue of the Journal of Materials Science : Materials in Electronics

In the last few decades the effect of lead contamination on human health has received significant attention. Based on such concerns, elimination of lead from ceramic glaze, paint, plumbing etc. has been legislated and implemented. However, until recently, solders used in electronics, based on suitability and knowledge-base developed over a long period of time, remained lead-based. Successive rapid advances in microelectronic devices in recent decades make them obsolete within a very short period after their introduction resulting in significant quantities of electronic wastes in landfills. Leaching of toxic lead from such electronic wastes can result in contamination of the human food chain causing serious health hazards. As a consequence, several European and Pacific Rim countries have passed legislations warranting elimination of lead from electronic solders by fast approaching deadlines. Global economic pressures brought on by such legislations have resulted in a flurry of research activities to find suitable lead-free substitutes for the traditional leaded electronic solders.

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Le raisonnement bayésien : Modélisation et inférence = Bayesian reasoning : Modeling and inference

Describes in detail the practice of the Bayesian statistical approach using many examples chosen for their educational interest. The first part gives the general principles of statistical modeling making it possible to supervise but also to come to the aid of the imagination of the apprentice modeler. By examining examples of increasing difficulty, the reader forges the keys to building their own model. The second part presents the most useful calculation algorithms for estimating the unknowns of the model. Each inference method is presented and illustrated by numerous application cases.

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Le piante e linquinamento dellaria ; 3rd ed.

Il volume approfondisce il complesso tema dei rapporti tra vegetazione e inquinanti dell’aria, affrontandone in modo capillare e ben documentato sia gli aspetti scientifici sia le implicazioni storico-culturali. La ricca iconografia a colori, l’approccio didattico, gli aggiornamenti normativi nazionali e comunitari, così come la dettagliata trattazione di tematiche quali la fitotossicologia, l’ecologia, la patologia vegetale, il biomonitoraggio, l'educazione ambientale e la valutazione di impatto ambientale, rendono il testo un sussidio indispensabile per i laureandi e gli specializzandi nelle Facoltà di Agraria e di Scienze Biologiche, Ambientali e Naturali

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Le manuel de réanimation, soins intensifs et médecine durgence = The manual of resuscitation, intensive care and emergency medicine

Offers an update of this book in a field that remains fascinating yet constantly evolving. Each chapter has been completely revised, expanded, and updated by the author. The didactic and practical approach has been maintained to ensure easy access for young doctors working in intensive care units, emergency physicians, and doctors on call in hospitals. These practitioners will find it helpful in understanding pathologies and implementing the most appropriate treatment.

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Le Distilbène trente ans après : Les enfants des 2èmes et 3èmes générations = Distilbene thirty years later : The children of the 2nd and 3rd generations

The various consequences on the anatomy and physiology of the female genitalia, as well as male, of children exposed in utero are reviewed. The impact on girls is greater than on boys: modification of the uterine cervix, reduction in the volume of the uterus with its consequences on fertility and the progress of pregnancies, risk of cancer of the vagina and the cervix. . The potential repercussions on the third generation are analyzed from experimental studies. Finally, the medico-legal implication is studied from the various trials that took place in the United States and from the first French trial that took place in Nanterre in November 2003. This work is the result of the collaboration of several experts recognized for their competence in this field. It will be of interest to all obstetrician gynecologists, urologists, but also public health physicians and midwives.

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Le dépistage du cancer du sein : un enjeu de santé publique = Breast cancer screening: a public health issue

Fifteen years after the first experiments, the breast cancer screening program was rolled out in France in 2004. It is aimed at more than eight million women aged 50 to 74. Public health action on such a scale is exemplary in Europe and especially in France where the health system is not centralized. The new edition of this book takes stock of the current state of the program and its initial results. It updates technical and radiological aspects, assessment indicators, communication and forensic problems and finally the progress of foreign programs. The history of the French program is detailed from the 1990s until 2006, with the publication of the latest version of the specifications by the Directorate General of Health. The short and medium term objectives are re-specified: to increase the participation of women, to retain them and to further improve the quality of practices. The challenge is to combine the performance of screening and therapeutic management to finally achieve a clear reduction in mortality, which has remained stable for twenty years.

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Le dépistage du cancer du col de lutérus = Cervical cancer screening

Each year, cervical cancer kills approximately 1,000 people in France, making it the fifth leading cause of cancer death and the eighth most common cancer among women. While eradicating cervical cancer is not possible, a national screening campaign should significantly reduce its incidence. This campaign should be based, in particular, on the systematic use of Pap smears. Conventional Pap smears have already reduced the number of invasive cancers by more than 50%. Improving them requires optimizing their sensitivity. This book details the natural history of cervical cancer, its incidence and mortality, and the various aspects of screening: general principles, the French screening program, the different types of Pap smears, the role and contribution of the HPV test, the management of abnormal Pap smears, the role of colposcopy, and the follow-up of treated women. It is intended for all those involved in this screening : specialist interns and gynecologists, pathologists and biologists, public health physicians, but also general practitioners whose role in screening is privileged since they are at the forefront of medical demand.

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Le dépistage du cancer colorectal : État des lieux et perspectives = Colorectal cancer screening: Current status and perspectives

Prevention and screening are two major challenges for Public Health to reduce cancer mortality in our country. Screening for colorectal cancer is therefore quite exemplary. The number one cancer in both sexes in France, its incidence continues to increase due to the aging of the population. Its mortality remains high, in the order of fifty percent, despite the major therapeutic advances made in recent years. Preceded by a precancerous lesion - the adenomatous polyp, which can be removed by colonoscopy - colorectal cancer is also curable at the early stage. Finally, it can be the subject of a screening strategy, the impact of which has been demonstrated today on the reduction in mortality, when it is detected before any symptom by a simple test for blood in the stool followed by , in case of positivity, by a total colonoscopy. This book takes stock of the scientific rationale and the state of play of organized colorectal cancer screening in France. It is also an opportunity to discuss emerging techniques and strategies that can help improve the results of this screening if they prove their superiority over the current strategy. Intended primarily for doctors, this book is also intended for healthcare professionals and all those who, concerned about their health, have a proactive attitude in terms of screening and preventing this cancer.

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