الصفحة 107
الصفحة 107
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The Local Cardiac Renin Angiotensin-Aldosterone System

How exciting it is to see a field so well established as the ren- angiotensin system continue to grow and mature. Originally, following the original identification of renin by Tigerstedt and Bergman over 100 years ago, workers in this area spent years attempting to establish its role in experimental and renal hypertension. The early work by Goldblatt, in 1934, demonstrated that the placement of a clip around a renal artery was clearly related to the subsequent development of hypertension.

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The Lisbon Treaty : EU Constitutionalism without a Constitutional Treaty?

When EU leaders signed the Lisbon Treaty in late 2007, it seemed that the constitutional process in Europe was close to fruition. This volume presents several works by renowned EU lawyers discussing the consequences of 'Lisbon' in various policy fields, as well as the pros and cons of the Union's 'constitution' as it stands with the Lisbon Treaty.

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The Link Between Inflammation and Cancer : Wounds that do not heal

The transcription factor NF-kB has long been known to play a central role in the immune system by regulating the expression of key genes. Moreover, activation of this transcription factor helps a wide variety of cell types survive damage induced by pro-apoptotic stimuli. Owing to its critical role in the regulation of pro-inflammatory genes, NF-kB has long been regarded as a promising target for the discovery of anti-inflammatory drugs. More recently, NF-kB has emerged as a major culprit in a variety of human cancers mainly due to its ability to protect transformed cells from apoptosis. This finding should not have come as a surprise since there exists a link between inflammation and many types of cancer which was already suggested by Galen and later demonstrated by Virchow. This link, of crucial importance for the design of novel strategies for cancer treatment, is the topic of this book.

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The Linearization Of Affixes : Evidence From Nuu-Chah-Nulth

The linearization of syntactic constructs stands at the forefront of current research on the syntax-phonology interface. This book examines the problem of linearization from a new perspective: that of the linearization of affixes. The driving proposal of this book is that affixation provides a means of satisfying the universal requirement that linguistic outputs be linearized. This hypothesis is tested against extensive original data from Nuu-chah-nulth ("Nootka"; Wakashan family), an endangered Amerindian language remarkable for its complex morphology. This volume introduces typologically rare affixation effects to current theoretical debates surrounding the division of labour between the modules of the grammar.

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The linear algebra : A beginning graduate student ought to know

Linear algebra is a living, active branch of mathematics which is central to almost all other areas of mathematics, both pure and applied, as well as computer science, the physical and social sciences, and engineering. It entails an extensive corpus of theoretical results as well as a large body of computational techniques.The volume is self-contained to the extent that it does not assume any previous formal knowledge of linear algebra.

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The Limits of Logical Empiricism : Selected Papers of Arthur Pap

This volume brings together a selection of the most philosophically significant papers of Arthur Pap. As Sanford Shieh explains in the Introduction to this volume, Pap’s work played an important role in the development of the analytic tradition. This role goes beyond the merely historical fact that Pap’s views of dispositional and modal concepts were influential. As a sympathetic critic of logical empiricism, Pap, like Quine, saw a deep tension in logical empiricism at its very best, in the work of Carnap. But Pap’s critique of Carnap is quite different from Quine’s, and represents the discovery of limits beyond which empiricism cannot go, where there lies nothing other than intuitive knowledge of logic itself. Pap’s arguments for this intuitive knowledge anticipate Etchemendy’s recent critique of the model-theoretic account of logical consequence.

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The Limits of Art : On Borderline Cases of Artworks and their Aesthetic Properties

This book is about exploring interesting borderline cases of art. It discusses the cases of gustatory and olfactory artworks (focusing on food), proprioceptive artworks (dance, martial arts, and rock climbing qua proprioceptive experiences), intellectual artworks (philosophical and scientific theories), as well as the vague limits between painting and photography.

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The life cycle of psychological ideas : Understanding prominence and the dynamics of intellectual change

Focuses on what other volumes have only touched on, that is the factors that contribute to the rise of certain persons and ideas in the field of psychology. Bringing together noted experts in the field, it describes the process of intellectual reconstructions that determines how we view historical events, and why some ideas die only to be reborn again, as well as why new ideas can quickly topple traditional views

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The Life Cycle of Entrepreneurial Ventures

Discusses topical issues in entrepreneurship organized around the various stages of venture creation, development and performance. The book is arranged in several parts, dealing with the pre-start stage, followed by venture creation, financing ventures, venture development, and venture performance. Each part contains several chapters written by experts in the relevant field. Like its predecessors, there are contributions from several disciplines, including economics, strategy, business, industrial organization, economic geography, finance and sociology. The multi-disciplinary flavor of the book is complemented by its international evidence base, featuring results from a range of different countries.

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The Life and afterlife of gay neighborhoods : Renaissance and resurgence

Examines the significance of gay neighborhoods (or ‘gayborhoods’) from critical periods of formation during the gay liberation and freedom movements of the 1960s and 1970s, to proven durability through the HIV/AIDS pandemic during the 1980s and 1990s, to a mature plateau since 2000. The book provides a framework for contemplating the future form and function of gay neighborhoods. Social and cultural shifts within gay neighborhoods are used as a framework for understanding the decades-long struggle for LGBTQ+ rights and equality.

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The Libyan Economy : Economic Diversification and International Repositioning

Delivers a thorough and essential analysis of current economic policy, transformation and legislative changes in Libya. The authors have comprehensively surveyed and analysed the country’s social development and trends, its current infrastructural deficit, and its often controversial foreign relations. Thereby, they answer many questions about Libya’s distinctive society and economic system and explain the necessity for the major restructuring of the Libyan economy which is currently in process.

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The Leydig Cell in Health and Disease

Nearly ten years after they published the first book devoted entirely to the Leydig cell, Matthew Hardy and Anita Payne have collaborated again to provide a comprehensive study of this fascinating and important cell type. The Leydig Cell in Health and Disease presents all of the developments in our understanding of Leydig cell biology and explores a wide variety of current and potential clinical applications. All aspects of Leydig cell biology, development, regulation, and physiology are explored in thirty-one expertly written chapters. The Leydig Cell in Health and Disease explores topics of great interest to the private sector, including the possible application of steroidogenesis discoveries to androgen synthesis or suppressing Leydig cell function as a key mechnanism in the development of a male contraceptive. This in-depth volume is an invaluable resource for information on the science and application of Leydig cell biology and function.

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The Legibility of Serif and Sans Serif Typefaces : Reading from Paper and Reading from Screens

Provides a detailed and up-to-date account of the relevant literature on the legibility of different kinds of typefaces, which goes back over 140 years in the case of reading from paper and more than 50 years in the case of reading from screens. It describes the origins of serif and sans serif styles in ancient inscriptions, their adoption in modern printing techniques, and their legibility in different situations and in different populations of readers. It also examines recent research on the legibility of serif and sans serif typefaces when used with internet browsers, smartphones and other hand-held devices. The book investigates the difference in the legibility of serif typefaces and sans serif typefaces when they are used to produce printed material or when they are used to present material on computer monitors or other screens and it explores the differences in readers’ preferences among typefaces.

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The LegalTech Book : The Legal Technology Handbook for Investors, Entrepreneurs and FinTech Visionaries

Written by prominent thought leaders in the global fintech and legal space, The LegalTech Book aggregates diverse expertise into a single, informative volume. Key industry developments are explained in detail, and critical insights from cutting-edge practitioners offer first-hand information and lessons learned.

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The Legal Environment and Risks for Foreign Investment in China

The Chinese market is appealing, but its legal environment is very complicated and full of nooses that await investors. This book intends to provide an in-depth analysis of the legal environment and its hidden risks for foreign investment.

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The Legacy of Mario Pieri in Geometry and Arithmetic

The Italian mathematician Mario Pieri (1860-1913) played an integral part in the research groups of Corrado Segre and Giuseppe Peano, and thus had a significant, yet somewhat underappreciated impact on several branches of mathematics, particularly on the development of algebraic geometry and the foundations of mathematics in the years around the turn of the 20th century. This book is the first in a series of three volumes that are dedicated to countering that neglect and comprehensively examining Pieri’s life, mathematical work, and influence in such diverse fields as mathematical logic, algebraic geometry, number theory, inversive geometry, vector analysis, and differential geometry.

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The Legacy of Felix Klein

Provides an overview of Felix Klein’s ideas, highlighting developments in university teaching and school mathematics related to Klein’s thoughts, stemming from the last century. It discusses the meaning, importance and the legacy of Klein’s ideas today and in the future, within an international, global context. Presenting extended versions of the talks at the Thematic Afternoon at ICME-13, the book shows that many of Klein’s ideas can be reinterpreted in the context of the current situation, and offers tips and advice for dealing with current problems in teacher education and teaching mathematics in secondary schools. It proves that old ideas are timeless, but that it takes competent, committed and assertive individuals to bring these ideas to life.

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The Legacies of Richard Popkin

Richard H. Popkin (1923-2005) transformed the study of the history of philosophy in the second half of the twentieth century. His History of Scepticism and his many other publications demonstrated the centrality of the problem of skepticism in the development of modern thought, the intimate connections between philosophy and religion, and the importance of contacts between Jewish and Christian thinkers. In this volume, scholars from around the world assess Popkin’s contributions to the many fields in which he was interested.

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The Lebanese financial crisis and it’s impact on Syrian Bank

Lebanon is now facing a deep financial crisis, and commercial banks face the worse liquidity stress in the country’s history. Researches done till now do not correlate other factors to each other and to the crisis. Those factors are mainly: banking activities and decisions, compliance, political issues, economic factors, as well as crisis and “black swans”. As Macroeconomic and financial factors may combine supporting economic development and so the Sustainable Development Goals (SDGs) set by the United Nations for a better and safer future for society, the significance of this study is that, by defining and analysing the fragility factors will assist to develop an effective and efficient early banking crisis warning system and developing a financial innovation framework which contributes to societies’ well-being.

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The lean CFO : Architect of the lean management accounting system

It’s about how a chief financial officer (CFO) becomes a Lean CFO to lead the transformation of a company’s management accounting system into a lean management accounting system.

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