الصفحة 103
الصفحة 103
Chemokines and Viral Infection
This edition of Current Topics in Microbiology and Immunology examines the role of chemokines and chemokine receptors in host defense and disease development following viral infection. Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory diseases and it was recognized that expression may be integral in leukocyte recruitment to inflamed tissue. There are now four sub-families of chemokines identified based on defined structural criteria relating to the positional location of conserved cysteine residues within the amino-terminus of the protein. Chemokines are now recognized as important in numerous biological processes ranging from maintaining the organizational integrity of secondary lymphoid tissue to participating in various aspects of both innate and adaptive immune responses following microbial infection. With this in mind, this book highlights the functional roles of chemokines and their receptors in participating in various aspects of the immune response against well-known viral pathogens.
Chemoinformatics and Bioinformatics in the Pharmaceutical Sciences
Chemoinformatics and Bioinformatics in the Pharmaceutical Sciences brings together two very important fields in pharmaceutical sciences that have been mostly seen as diverging from each other: chemoinformatics and bioinformatics. As developing drugs is an expensive and lengthy process, technology can improve the cost, efficiency and speed at which new drugs can be discovered and tested. This book presents some of the growing advancements of technology in the field of drug development and how the computational approaches explained here can reduce the financial and experimental burden of the drug discovery process.
Chemistry and Safety of Acrylamide in Food
Specifically covered are the following aspects: exposure from the environment and the diet; biomarkers of exposure; risk assessment; epidemiology; mechanism of formation in food; biological alkylation of amino acids, peptides, proteins, and DNA by acrylamide and its epoxide metabolite glycidamide; neurotoxicity, reproductive toxicity, and carcinogenicity; protection against adverse effects; and possible approaches to reducing levels in food. Cross-fertilization of ideas among several disciplines in which an interest in acrylamide has developed, including food science, pharmacology, toxicology, and medicine, will provide a better understanding of the chemistry and biology of acrylamide in food, and can lead to the development of food processes to decrease the acrylamide content of the diet.
Chemical product formulation design and optimization : methods, rechniques, and case studies
A team of renowned technologists and engineers delivers a practice guide to chemical product design. Offering real-world case studies for disinfectant formulation, the optimization of defined media, and the formulation of biocomposites, the book contains introduction to the current product design process. A practical approach to the essentials of product design, related statistical techniques and optimization, patents, green chemistry and gives real life case studies.
Chemical process engineering ; Vol.1 : Design, analysis, simulation, integration, and problem solving with microsoft Excel-UniSim software for chemical engineers computation, physical Property, fluid flow, equipment and instrument sizing
The book provides a detailed description and hands-on experience on process design in chemical engineering, and it is an integrated text that focuses on practical design with new tools, such as Excel spreadsheets and UniSim simulation software.
Chemical Kinetics and Reaction Dynamics
Chemical Kinetics and Reaction Dynamics brings together the major facts and theories relating to the rates with which chemical reactions occur from both the macroscopic and microscopic point of view. This book helps the reader achieve a thorough understanding of the principles of chemical kinetics and includes: *Detailed stereochemical discussions of reaction steps / *Classical theory based calculations of state-to-state rate constants / *A collection of matters on kinetics of various special reactions such as micellar catalysis, phase transfer catalysis, inhibition processes, oscillatory reactions, solid-state reactions, and polymerization reactions at a single source. / The growth of the chemical industry greatly depends on the application of chemical kinetics, catalysts and catalytic processes.
Chemical Evolution and the Origin of Life
Up to now, we do not have a generally accepted theory about the origin of life and about the process of development of life, we only have a great number of - to some extent even contradictory – hypotheses. Meanwhile there came up some scientific findings beyond thought only a few years ago.Horst Rauchfuss is comparing the different theories from the view of the latest results and is giving an exciting and easy understandable insight into the present state of research.
Chemical components in some winter vegetables and their effectiveness in treating diseases
Cruciferous (Brassicaceae) vegetables comprise many important species cultivated worldwide and utilized traditionally for culinary and medicinal purposes in different cultures. In the last couple of decades, growing scientific evidence has suggested that consumption of cruciferous vegetables has a preventive role against a variety of human diseases. This prompted the development of nutritional ingredients derived from these vegetables and their use as dietary supplements in different formulations that contain complete plant extracts or specific compounds...
Chemical and functional properties of food components
Described the contents of food raw materials and products, the chemistry/biochemistry of food components, as well as the changes occurring during post-harvest storage and processing affecting the quality of foods. Discusses the role of chemical compounds in the structure of raw materials and the formation of different attributes of food quality, including nutritional value, safety, and sensory properties. It contains four new chapters: “Non-Protein Nitrogenous Compounds”; “Prooxidants and Antioxidants in Food”; “Non-Nutritive Bioactive Compounds in Food of Plant Origin”; and “Analytical Methods Used for Assessing the Quality of Food Products.”
Charting a new course : Natural language processing and information retrieval : Essays in Honour of Karen Spärck Jones
This book celebrates the life and work of Karen Spärck Jones in her seventieth year. she is one of the major figures of 20th century and early 21st Century computing and information processing. It book consists of fifteen new and original chapters written by leading international authorities reviewing the state of the art and her influence in the areas in which Karen Spärck Jones has been active. Although she has a publication record which goes back over forty years, it is clear even the very early work reviewed in the book can be read with profit by those working on recent developments in information processing like bioinformatics and the semantic web.
Characterization of Polymer Surfaces and Thin Films
Comprehensive characterization of surfaces and interfaces is essential to relate surface and thin film properties to micro structure and molecular origin, which is, on the other hand, the key to technological control and improvement of materials. This volume cover a representative spectrum of surface sensitive techniques and their application to polymer surface and thin film characterization as well as recent examples of technologically relevant materials and process development.
Characteristic based planning with mySAP SCM™ : Scenarios, processes, and functions
Characteristics are used in SAP as attributes, e.g. to specify the configuration of products or the properties of batches. In many industries – engineering, automotive, mill, pharmaceutical and foods to name the most typical – supply chain planning has to consider these characteristics. APO offers many different functionalities for planning with characteristics, where each of the functionalities has some prerequisites and incompatibilities. This book offers help and advice for the basic design of the implementation by explaining the processes and scenarios (process chains) for planning with characteristics, the functionalities for planning with characteristics in APO including their prerequisites and incompatibilities and the entities, dependencies and system configuration determinants for planning with characteristics in R/3 and APO. This book is based on the releases R/3 4.7 and mySAP SCM 4.1.
Channel strategies and marketing mix in a connected world
Aims to revisit the “traditional” interaction between channel strategies and the marketing mix in a connected world. In particular, it focuses on the following four dimensions in this context: Consumers, Products, Value Proposition and Sustainability. Keeping in mind the growing digitalization of business processes in the retail world and the move towards omni-channel retailing.
Changing Land Use Patterns in the Coastal Zone : Managing Environmental Quality in Rapidly Developing Regions
Coastal ecosystems make up some of the most important, yet most endangered, regions in the world. The protection of the unique processes that take place in these ecosystems requires that partnerships be formed among ecologists, resource managers, and planners. Experienced in the challenges of coastal system analysis, the contributors to this book provide multidisciplinary guidance on the assessment and management of environmental impacts caused by development. Each chapter examines an issue important to these fragile ecosystems, first presenting a non-technical summary of the issue and a review of the current state of the knowledge, then following with data and a more detailed consideration of the topic.
Change from the Inside Out : Making you, your team, and your organization change-capable
Change initiatives fail because humans are hardwired to return to what's worked for them in the past. This book offers a straightforward process for building support for change from the ground up
Chance : The life of games and the game of life
With its many easy-to-follow mathematical examples, this book takes the reader on an almost chronological trip through the fascinating and amazing laws of chance, omnipresent in the natural world and in our daily lives. Along the route many fascinating topics are discussed, such as: challenging probability paradoxes; "paranormal" coincidences; game odds; causes and effects; interpretation of opinion polls; winning chances as a game proceeds; the nature of randomness; entropy and randomness; randomness in life; algorithmic complexity and the undecidability of randomness; possibilities and limitations of learning the laws of a Universe immersed in chance events. This charming book will inform and entertain the scientist and non-scientist alike.
Challenges of expanding internet : E-commerce, e-business, and e-government ; 5th IFIP conference on e-commerce, e-business, and e-government (I3E'2005), October 28-30 2005, Poznan, Poland
This book constitutes the refereed proceedings of the5th IFIP Conference e-Commerce, e-Business, and e-Government (I3E’2005), 2005, Poznan, Poland This collection of papers offers Topics e-Commerce/e-business Sales/Distribution / Information Systems Applications (incl. Internet) / Computer Communication Networks / Cryptology / Database Managemen
Challenges in Pediatric Kidney Transplantation : A practical guide
This book provides a comprehensive overview of the unique challenges inherent in pediatric kidney transplantation. The text reviews the problems faced during each stage of the kidney transplantation process, including the occurrence of infections during the pre-transplant stage, surgical challenges during the actual transplantation, and medication issues during the post-transplant stage. The book also features high-yield case presentations of typical pediatric transplant scenarios, from the pre-transplant management of a child with CAKUT to the evaluation and treatment of antibody mediated rejection in children.
Challenges in Ad Hoc Networking ; 4th Annual Mediterranean Ad Hoc Networking Workshop, June 21-24, 2005, Île de Porquerolles, France
The IFIP series publishes state-of-the-art results in the sciences and technologies of information and communication. The scope of the series includes: foundations of computer science; software theory and practice; education; computer applications in technology; communication systems; systems modeling and optimization; information systems; computers and society; computer systems technology; security and protection in information processing systems; artificial intelligence; and human-computer interaction. Proceedings and post-proceedings of referred international conferences in computer science and interdisciplinary fields are featured. These results often precede journal publication and represent the most current research.
Challenges and negotiations for women in higher education
There is much ambivalence in women’s experience of the academy as teachers and students. Although today many more women follow academic careers than in the past, they do not find the welcome that they had hoped for and expected. Additionally, women students find that whilst they can now enter through the doors of universities, academic space remains embedded in structures and cultures of gender and social class. This book is a clear and accessible exploration of lifelong learning and educational opportunities for women in higher education. It has been developed from work undertaken by members of the Women in Higher Education Network with chapters organised in three thematic sections: Ambivalent Positions in the Academy / Process and Pedagogy at Work / Career – Identity – Home
