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الصفحة 1
الصفحة 1
Mass Vaccination : Global Aspects - Progress and Obstacles
Mass immunization is the blitzkrieg of vaccination practice. It serves to rapidly protect populations, both because of the high coverage achieved and because of the herd immunity thereby induced. However, as in war, mass immunization campaigns must be conducted intelligently, with careful strategy and strong attention to logistics of supply and deployment. If conducted badly, mass immunization may fail or even be counter-productive. In this volume, some of the most successful practitioners of mass im- nization tell us about its art and science. David Heymann and Bruce Aylward of WHO begin the book with a theoretical and practical overview of mass immunization. Michael Lane, who participated in the successful effort to eradicate smallpox relates how this was done using mass vaccination and other strategies. Application of mass immunization by the US military is c- ered by John Grabenstein and Remington Nevin, who have a large experience in these matters. Karen Noakes and David Salisbury recount the striking s- cesses of mass immunization in the United Kingdom. The global control of the clostridia that produce diphtheria toxin is described by Charles Vitek. Hepa- tis A is decreasing dramatically under the impact of large-scale vaccination, as Francis André illustrates. The French experience with Hepatitis B vac- nation has been mixed, and François Denis and Daniel Levy-Bruhl explain the circumstances. In?uenza vaccination is an annual example of large-scale campaigns, the complexity of which is recounted by Benjamin Schwartz and Pascale Wortley.
Le dépistage du cancer du col de lutérus = Cervical cancer screening
Each year, cervical cancer kills approximately 1,000 people in France, making it the fifth leading cause of cancer death and the eighth most common cancer among women. While eradicating cervical cancer is not possible, a national screening campaign should significantly reduce its incidence. This campaign should be based, in particular, on the systematic use of Pap smears. Conventional Pap smears have already reduced the number of invasive cancers by more than 50%. Improving them requires optimizing their sensitivity. This book details the natural history of cervical cancer, its incidence and mortality, and the various aspects of screening: general principles, the French screening program, the different types of Pap smears, the role and contribution of the HPV test, the management of abnormal Pap smears, the role of colposcopy, and the follow-up of treated women. It is intended for all those involved in this screening : specialist interns and gynecologists, pathologists and biologists, public health physicians, but also general practitioners whose role in screening is privileged since they are at the forefront of medical demand.
Le dépistage du cancer bronchique : De l'espoir à la réalité = Lung cancer screening : From hope to reality
An ambitious program has been launched in terms of research, diagnosis, prevention, and screening. Among cancers, the leading cause of cancer death is lung cancer. This disease, so closely linked to behavioral habits, both focuses and encapsulates the problem. Despite constant progress in treatment, the prognosis remains bleak, explaining the fatalistic impression left by the last decade. While significant efforts were being made in screening for other cancer sites, lung cancer remained in the shadows, with studies showing limited effectiveness in this approach. The advent of spiral CT scanning has revolutionized the field, giving rise to new hope alongside anti-smoking campaigns. Autofluorescence endoscopy, by enabling the diagnosis of pre-neoplastic lesions, completes an arsenal that finally allows us to envision an effective, combined strategy. This book brings together all the elements relating to screening and early diagnosis. The road from hope to reality is long, but we must acknowledge that, for the first time, we know it exists.
Applied biophysics for drug discovery
It is a guide to new techniques and approaches to identifying and characterizing small molecules in early drug discovery. Biophysical methods are reasserting their utility in drug discovery and through a combination of the rise of fragment-based drug discovery and an increased focus on more nuanced characterisation of small molecule binding, these methods are playing an increasing role in discovery campaigns.
Marketing metrics : Leverage analytics and data to optimize marketing strategies
Featuring examples from a range of organizations including Coca-Cola and Mercedes-Benz, it shows how to create a strategy which leverages consumer data for customer-centric marketing, establishes the ROI of channels and campaigns, strengthens brands and creates data-driven product strategies. Covering the range of new global laws that impact consumer privacy and data collection and usage, Marketing Metrics shows how to use data in a non-invasive, secure and ethical way.
Advertising management : Concepts, theories, research and trends
Explores the concept of advertising and the different ways advertising is understood and evaluated. It dives deep into planning, designing, and executing advertising campaigns on different mediums. It discusses the theoretical and research parts of advertising by critically examining how over the years various hierarchical models and theories are developed by advertising experts. It examines various models and theories that explain why and how advertising is successful in persuading customers target audiences to buy a product or accept an idea for behavioural change.
Kristian Birkeland : The First Space Scientist
PREFACEThisscientific biography of Kristian Birkeland (1867–1917) was written to bring the story ofa Norwegian national hero to the attention ofthe English-speaking world. Birkeland’sheroic stature was established not on a field of military battle,but in the bitter cold of the Artic wilderness ashe sought to answer basic questions abouthow the Sun controlled northern lights andmag-netic storms. He was also afather of Norsk Hydro one ofNorway’s largest industries. Birkel and died before reaching the age of 50.Because Birkel and never kept adiary, documented information about his family and private life is sparse. Before he died, Olaf Devik, the last of Birke-ffland’s close friends, gave along interview and graciously transferred his personal archive to A.E. Birkeland’s 82 scientific papers and three book-length publications map the progress of his investigations. addressed this book questions that had vexed European scientists for centuries. Why do the northern lights appear overhead when the Earth’s magnetic field is disturbed? How are magnetic storms connected to disturbances on the Sun? To answer these questions Birkeland interpreted his advance laboratory simulations and daring campaigns in the Arctic wilderness in the light of Maxwell’s newly discovered laws of electricity and magnetism. Birkeland’s ideas were dismissed for decades, only to be vindicated when satellites could fly above the Earth’s atmosphere.
Bearing Witness : Ruth Harrison and British Farm Animal Welfare (1920–2000)
This book is the biography of one of Britain’s foremost animal welfare campaigners and of the world of activism, science, and politics she inhabited. In 1964, Ruth Harrison’s bestseller Animal Machines triggered a gear change in modern animal protection by popularising the term ‘factory farming’ alongside a new way of thinking about animal welfare.
Anti-vivisection and the profession of medicine in Britain : A social history
This book explores the social history of the anti-vivisection movement in Britain from its nineteenth-century beginnings until the 1960s. It discusses the ethical principles that inspired the movement and the socio-political background that explains its rise and fall. Opposition to vivisection began when medical practitioners complained it was contrary to the compassionate ethos of their profession. Christian anti-cruelty organizations took up the cause out of concern that callousness among the professional classes would have a demoralizing effect on the rest of society. As the nineteenth century drew to a close, the influence of transcendentalism, Eastern religions and the spiritual revival led new age social reformers to champion a more holistic approach to science, and dismiss reliance on vivisection as a materialistic oversimplification.
