Applied biophysics for drug discovery
- المؤلف
- Donald Preston Huddler, Edward Zartler
- سنة النشر
- 2017
- الناشر
- Wiley
- لغة الملف
- انكليزي
- نوع الملف
- Book
- تصنيف الكتاب
- Medical Science
- تحميل الكتاب قراءة الكتاب
It is a guide to new techniques and approaches to identifying and characterizing small molecules in early drug discovery. Biophysical methods are reasserting their utility in drug discovery and through a combination of the rise of fragment-based drug discovery and an increased focus on more nuanced characterisation of small molecule binding, these methods are playing an increasing role in discovery campaigns.
الكلمات المفتاحية: Drug Discovery / Thermodynamics of Biomolecular Interactions / Isothermal Titration Calorimetry / Thermodynamic Rules of Thumb / Fragment‐Based Drug Design / Enthalpic Screening / Protein–Protein Interactions / Microscale Thermophoresis in Drug Discovery / Weak Affinity Chromatography / NMR Methods /
