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Alzheimer : 100 Years and Beyond
Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4th, 1906 in Tübingen. The celebratory event, "Alzheimer 100 Years and Beyond" organized on the initiative of the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen, at the very site of the original lecture, namely the Institute of Psychiatry at the University of Tübingen in Germany from November 2nd to 5th, 2006, was the highlight of the Alzheimer Year. Over the last century of Alzheimer research (1906-2006), remarkable progress has been achieved. Most of the authors of the major discoveries and the people involved in research in this field will present, during the meeting and in this volume, the pioneering research explaining the conditions under which they were conducted. The goal of this book is to honor the work accomplished, to summarize the most important knowledge and to provide material for the history of science.
Alternative Splicing and Disease
Splicing of primary RNA transcript, i.e. removal of introns and joining of exons to produce mature mRNAs competent for translation into proteins, is a quasi-systematic step of gene expression in higher organisms. However, this process is not unequivocal but can follow alternate pathways. Alternative splicing of a given transcript can therefore yield several distinct mRNAs encoding as many different proteins. Its full biological significance has not been appreciated until it was recognized that alternative splicing is so general as to affect about 75% of all human genes. Therefore, alternative splicing not only vastly increases protein diversity but also offers numerous opportunities for aberrant splicing events with pathological consequences.
Alternative pseudodifferential analysis : With an application to modular forms
This volume introduces an entirely new pseudodifferential analysis on the line, the opposition of which to the usual (Weyl-type) analysis can be said to reflect that, in representation theory, between the representations from the discrete and from the (full, non-unitary) series, or that between modular forms of the holomorphic and substitute for the usual Moyal-type brackets. This pseudodifferential analysis relies on the one-dimensional case of the recently introduced anaplectic representation and analysis, a competitor of the metaplectic representation and usual analysis.
Alternative Education : Global Perspectives Relevant to the Asia-Pacific Region
Alternative streams of education have been and remain an important but difficult theme for teachers, parents, policy-makers, and scholars. By focusing on case studies of six countries (Bolivia, Thailand, Australia, USA, The Netherlands, and Denmark), and by comprehensively analysing these by means of international comparative methodologies, the author approaches the nuts and bolts issues of alternative and mainstream education systems. The case studies include Charter Schools in the USA and Waldorf Schools in Australia. The study presents not only an insightful analysis of alternative forms of education with regard to actual issues in societies and also legal and administrative features of education. It provides insights into the kind of school development that could be appropriate in the 21st century and the types of educational communities we should seek to create in the age of globalisation.
Alternative concrete - geopolymer concrete : Emerging research and opportunities
Focuses on fly ash-based alkali-activated geopolymer concrete, its production and characteristic properties. The re-use of waste materials and industrial by-products, such as fly ash, is not only economically of interest but also helps to reduce carbon dioxide emissions. The carbon footprint of these materials is much lower than that of concrete using ordinary Portland cement. They thus offer new sustainable solutions to the construction industry.
Alpha-1 antitrypsin : Methods and protocols
Provides a collection of protocols that will allow researchers to further explore the multiple, fascinating activities of Alpha-1 Antitrypsin (AAT) isoforms in innate immunity, and gene therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Algorithms for a New World : When Big Data and Mathematical Models Meet
Algorithms, artificial neural networks, and machine learning help us discover the opportunities and pitfalls of a world governed by mathematics and artificial intelligence.
Algebra and Coalgebra in Computer Science; First International Conference, CALCO 2005, Swansea, UK, September 3-6, 2005, Proceedings
CALCO, the Conference on Algebra and Coal-gebra in Computer Science, was created to bring together researchers and practitio-ners to exchange new results related to foundational aspects, and both traditional and emerging uses of algebras and coalgebras in computer science. CALCO 2005 was the first instance of this new conference. The interest that it generated in the scientific community suggests that it will not be the last. Indeed, it attracted as many as 62 submissions covering a wide range of topics roughly divided into two areas: Algebras and Coalgebras as Mathematical Objects: Automata and languages; categorical semantics; hybrid, probabilistic, and timed systems; inductive and coin-ductive methods; modal logics; relational systems and term rewriting.
AI*IA 2005 : Advances in artificial intelligence ; 9th congress of the Italian Association for Artificial Intelligence Milan, Italy, September 21-23, 2005, Proceedings
This volume collects the papers selected for presentation at the IX Congress of the Italian Association for Arti?cial Intelligence (AI*IA), 2005 On the one hand this congress continues the tradition of AI*IA in organizing its biannual s- enti?c meeting from 1989; on the other hand, this edition is a landmark in the involvement of the international community of arti?cial intelligence (AI), directly involving a broad number of experts from several countries in the P- gramCommittee. Moreover,the peculiar nature of scienti?c researchin arti?cial intelligence (which is intrinsically international) and several consolidated int- national collaborations in projects and mobility programs allowed the collection and selection of papers from many di?erent countries, all around the world, enlarging the visibility of the Italian contribution within this research ?eld. Arti?cial intelligence is today a growing complex set of conceptual, theor- ical, methodological, and technological frameworks, o?ering innovative com- tational solutions in the design and development of computer-based systems. Within this perspective, researchers working in this area must tackle a broad range of knowledge about methods, results, and solutions coming from di?erent classical areas of this discipline. The congress was designed as a forum allowing researchers to present and discuss specialized results as general contributions to AI growth.
AI in learning : Designing the future
AI (artificial intelligence) is predicted to radically change teaching and learning in both schools and industry causing radical disruption of work. AI can support well-being initiatives and lifelong learning but educational institutions and companies need to take the changing technology into account. Moving towards AI supported by digital tools requires a dramatic shift in the concept of learning, expertise and the businesses built off of it. Based on the latest research on AI and how it is changing learning and education, this book will focus on the enormous opportunities to expand educational settings with AI for learning in and beyond the traditional classroom. This book also introduces ethical challenges related to learning and education, while connecting human learning and machine learning.
AI in disease detection : Advancements and applications
Discusses the integration of artificial intelligence to revolutionize disease detection approaches, with case studies of AI in disease detection as well as insight into the opportunities and challenges of AI in healthcare as a whole. The book explores a wide range of individual AI components such as computer vision, natural language processing, and machine learning as well as the development and implementation of AI systems for efficient practices in data collection, model training, and clinical validation.
Aging Well : Solutions to the Most Pressing Global Challenges of Aging
Outlines the challenges of supporting the health and wellbeing of older adults around the world and offers examples of solutions designed by stakeholders, healthcare providers, and public, private and nonprofit organizations in the United States. The solutions presented address challenges including: providing person-centered long-term care, making palliative care accessible in all healthcare settings and the home, enabling aging-in-place, financing long-term care, improving care coordination and access to care, delivering hospital-level and emergency care in the home and retirement community settings, merging health and social care, supporting people living with dementia and their caregivers, creating communities and employment opportunities that are accessible and welcoming to those of all ages and abilities, and combating the stigma of aging. The innovative programs of support and care in Aging Well serve as models of excellence that, when put into action, move health spending toward a sustainable path and greatly contribute to the well-being of older adults.
Agile processes in software engineering and extreme programming ; 17th International Conference, XP 2016, Edinburgh, UK, May 24-27, 2016, Proceedings
Contains the refereed proceedings of the 17th International Conference on Agile Software Development, XP 2016, held in Edinburgh, UK, in May 2016. While agile development has already become mainstream in industry, this field is still constantly evolving and continues to spur an enormous interest both in industry and academia. To this end, the XP conference attracts a large number of software practitioners and researchers, providing a rare opportunity for interaction between the two communities.
Agile Marketing Performance Management : 10 Success Factors for Maximizing Marketing ROI Dynamically
Helps marketing decision makers in allocating their budget to diverse communication channels and different business units in an ROI-optimal way, and to adapt it in an agile manner.
Agile Development with the ICONIX Process : People, Process, and Pragmatism
Describes how to apply ICONIX Process (a minimal, use case-driven modeling process) in an agile software project. It's full of practical advice for avoiding common agile pitfalls. Further, the book defines a core agile subset so those of you who want to get agile need not spend years learning to do it. Instead, you can simply read this book and apply the core subset of techniques. The book follows a real-life .NET/C# project from inception and UML modeling, to working code through several iterations. You can then go on-line to compare the finished product with the initial set of use cases. The book also introduces several extensions to the core ICONIX Process, including combining test-driven development (TDD) with up-front design to maximize both approaches (with examples using Java and JUnit). And the book incorporates persona analysis to drive the projects goals and reduce requirements churn.
Agents and peer-to-peer computing ; Vol. 4118 : 4th International workshop, AP2PC 2005, Utrecht, Netherlands, J uly 25, 2005, Revised and Invited Papers
Constitutes the thoroughly refereed post-proceedings of the 4th International Workshop on Agents and Peer-to-Peer Computing, AP2PC 2005, held in Utrecht, Netherlands, July 2005, in the context of the 4th International Joint Conference on Autonomous Agents and Multi-Agent Systems, AAMAS 2005. The 13 revised full papers cover trust and reputation, P2P infrastructure, semantic infrastructure, as well as community and mobile applications.
Agents and peer-to-peer computing ; Vol. 3601 ; 3rd international workshop, AP2PC 2004, New York, NY, USA, July 19, 2004, revised and invited papers
This volume presents the fully revised papers presented at the Third International Workshop on Agents and Peer-to-Peer Computing, AP2PC 2004, held in New York City on July 19, 2004 in the context of the Third International Joint Conference on Autonomous Agents and Multi-Agent Systems (AAMAS 2004). The volume is organized in topical sections on P2P networks and search performance, emergent communities and social behaviours, semantic integration, mobile P2P systems, adaptive systems, agent-based resource discovery, as well as trust and reputation.
Agent-mediated electronic commerce VI ; Theories for and engineering of distributed mechanisms and systems, AAMAS 2004 Workshop, Amec 2004, New York, NY, USA, July 19, 2004, revised selected papers
The design of intelligent trading agents, mechanisms, and systems has receivedgrowing atttention in the agents and multiagent systems communities in aneffort to address the increasing costs of search, transaction, and coordinationwhich follows from the increasing number of Internet-enabled distibuted elec-tronic markets. Furthermore, new technologies and supporting business modelsare resulting in a growing volume of open and horizontally integrated markets fortrading of an increasingly diverse set of goods and services. However, growth oftechnologies for such markets requires innovative solutions to a diverse set of ex-isting and novel technical problems which we are only beginning to understand.Specifically, distributed markets present not only traditional
Agent Intelligence Through Data Mining
AGENT INTELLIGENCE THROUGH DATA MINING offers a self-contained overview of a relatively young but important area of research: the intersection of agent technology and data mining. This intersection leads to considerable advancements in the area of information technologies, drawing the increasing attention of both research and industrial communities. It can take two forms: a) the more mundane use of intelligent agents for improved data mining and; b) the use of data mining for smarter, more efficient agents. The second approach is the main focus of this volume. this book presents a methodology for developing multi-agent systems, describes available open-source tools to support this process, and demonstrates the application of the methodology on three different cases. AGENT INTELLIGENCE THROUGH DATA MINING is designed for a professional audience composed of researchers and practitioners in industry.
African Land Reform Under Economic Liberalisation: States, Chiefs, and Rural Communities
This book offers unique in-depth, comprehensive, and comparative analyses of the motivations, context, and outcomes of recent land reforms in Africa. Whereas a considerable number of land reforms have been carried out by African governments since the 1990s, no systematic analysis on their meaning has so far been conducted. In the age of land reform, Africa has seen drastic rural changes. Analysing the relationship between those reforms and change, the chapters in this book reveal not only their socio-economic outcomes, such as accelerated marketisation of land, but also their political outcomes, which have often been contrasting.
