Biophysical characterization of functional peptides
Presents reproducible and step-by-step procedures for the peptide synthesis, their characterization and applications. The volume includes an introductory section on in silico modelling of new peptide molecules, Molecular Dynamics Simulations, Docking, Electrostatic fingerprinting of peptides, and other modelling tools for peptide designing and optimization. Further, it covers protocols for the solid phase peptide synthesis, chromatographic and mass spectrometric characterization of peptides. Importantly, it covers methods for biophysical characterizations of peptides for their potential applications as drug delivery vehicles, peptide nano-assembly, bionanocatalysis, protein aggregation diseases, and peptide-based anti-bacterial.
Bio-mechanisms of swimming and flying ; Fluid dynamics, biomimetic robots, and sports science
This book follows "Bio-mechanisms of Animals in Swimming and Flying" published in 2004 including 11 chapters. This time, the book includes 31 chapters on the latest researches into natural autonomous systems and locomotion in both flying and swimming organisms. The area of sports science such as analysis and simulation of human swimming is newly added. The computational frameworks for the modeling, simulation and optimization of animals in swimming and flying demonstrate an important role in the progress of interdisciplinary work in the fields of biology and engineering. An innovative technology is exhibited for the flight of an insect size micro air vehicle. Neuronal science is not only unveiling the locomotion mechanisms of swimming in fish from the aspect of the neuronal activities, but also applied to underwater biomimetic robots. The interdisciplinary works are exhibited in the fields of biology and engineering, yielding real-world benefits in innovative technologies.
Basic pharmacokinetics
Introduces basic pharmacokinetic concepts to beginner learners to help them understand the absorption, distribution, metabolism, and excretion of drugs. Accompanying the book is a website with self-instructional tutorials and pharmacokinetic and pharmacokinetic-pharmacodynamic simulations, allowing visualization of concepts for enhanced comprehension. This learning tool received an award from the American Association of Colleges of Pharmacy for innovation in teaching, making it a valuable supplement to this essential text.
Anticancer activity in heterocyclic organic structures : A pathway to novel drug development : Part 1
New Directions in Organic & Biological Chemistry, explores the development of cancer therapeutics, focusing on molecular chemistry and advanced drug design approaches. Written by experts in theoretical chemistry and molecular chemistry, they bridge the gap between theoretical chemistry, molecular biology, and drug development. In Part I, they focus on the fundamental properties of heterocyclic compounds and innovative methodologies being employed to enhance therapeutic potential. By exploring various classes of heterocyclic compounds and diverse anticancer mechanisms.
Advances in pharmacokinetics and pharmacodynamics
Provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using PBPK modeling (Chapter 2). Chapters 3 and 4 describe the recent development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) models and their applications to pharmacokinetic data. The pharmacodynamics section focuses on PK/PD modeling. Chapter 5 provides an overview of PK/PD modeling and simulation in clinical practice and studies. Chapter 6 deals with the subject/physiology variability issue encountered in PK/PD studies, while Chapter 7 reviews the influence of clinical pharmacology in the modernization of drug development and regulation. This book is an essential reference for pharmaceutical scientists.
Advances in cognitive neurodynamics ICCN 2007; Proceedings of the International conference on cognitive neurodynamics - 2007
Contains the Proceedings of the 1st International Conference on Cognitive Neurodynamics held in Shanghai, November 17-21, 2007. The participants were treated to an exciting and stimulating conference that left everyone with an enthusiastic vision for the future of the field. The latest important progress was covered by 13 mini-symposia including: Models of Mental Disorders; Cognitive Machines; Dynamics in learning and memory; Central nervous system synchronization; Neuroinformatics; Cognitive Computational Modeling of Human Language Processing; Cognitive Neurodynamics of Attention; Bottom-Up and Top-Down; Brain Networks; From Anatomy to Dynamics; Translational Cognitive Neuroimaging; K-sets; Theory and Applications; Advanced Signal Processing Techniques for Brain Data Analysis; Visual cortex: information processing and dynamics; Dynamics of Firing Patterns and Synchronization in Neuronal Systems.
Macroscopic Transport Equations for Rarefied Gas Flows : Approximation Methods in Kinetic Theory
This book discusses classical and modern methods to derive macroscopic transport equations for rarefied gases from the Boltzmann equation, for small and moderate Knudsen numbers, i.e.as well as the new order of magnitude method, which avoids the short-comings of the classical methods, but retains their benefits.
Machine Learning for Multimedia Content Analysis
Challenges in complexity and variability of multimedia data have led to revolutions in machine learning techniques. Multimedia data, such as digital images, audio streams and motion video programs, exhibit richer structures than simple, isolated data items. A number of pixels in a digital image collectively conveys certain visual content to viewers. A TV video program consists of both audio and image streams that unfold the underlying story. To recognize the visual content of a digital image, or to understand the underlying story of a video program, we may need to label sets of pixels or groups of image and audio frames jointly.
Machine learning and its application to reacting flows: ml and combustion
These two fields, ML and turbulent combustion, have large body of work and knowledge on their own, and this book brings them together and explain the complexities and challenges involved in applying ML techniques to simulate and study reacting flows. This is important as to the world’s total primary energy supply (TPES), since more than 90% of this supply is through combustion technologies and the non-negligible effects of combustion on environment. Although alternative technologies based on renewable energies are coming up, their shares for the TPES is are less than 5% currently and one needs a complete paradigm shift to replace combustion sources. The book covers the current state of the art in these two topics and outlines the challenges involved, merits and drawbacks of using ML for turbulent combustion simulations including avenues which can be explored to overcome the challenges.
Machine Learning and Big Data Analytics Paradigms : Analysis, Applications and Challenges
Intended to present the state of the art in research on machine learning and big data analytics. The accepted chapters covered many themes including artificial intelligence and data mining applications, machine learning and applications, deep learning technology for big data analytics, and modeling, simulation, and security with big data. It is a valuable resource for researchers in the area of big data analytics and its applications.
LNA-ESD Co-Design for Fully Integrated CMOS Wireless Receivers
LNA-ESD Co-Design for Fully Integrated CMOS Wireless Receivers fits in the quest for complete CMOS integration of wireless receiver front-ends. With a combined discussion of both RF and ESD performance, it tackles one of the final obstacles on the road to CMOS integration.
Laser additive manufacturing: design, materials, processes and applications
Laser-based additive manufacturing (LAM) is a revolutionary advanced digital manufacturing technology developed in recent decades, which is also a key strategic technology for technological innovation and industrial sustainability. This technology unlocks the design and constraints of traditional manufacturing and meets the needs of complex geometry fabrication and high-performance part fabrication. A deeper understanding of the design, materials, processes, structures, properties and applications is desired to produce novel functional devices, as well as defect-free structurally sound and reliable LAM parts.The topics in this Special Issue reprint include macro- and micro-scale additive manufacturing with lasers, such as structure/material design, fabrication, modeling and simulation, in situ characterization of additive manufacturing processes and ex situ materials characterization and performance, with an overview that covers various applications in aerospace, biomedicine, optics and energy.
Knowledge Sharing in the Integrated Enterprise : Interoperability Strategies for the Enterprise Architect
The IFIP series publishes state-of-the-art results in the sciences and technologies of information and communication. The scope of the series includes: foundations of computer science; software theory and practice; education; computer applications in technology; communication systems; systems modeling and optimization; information systems; computers and society; computer systems technology; security and protection in information processing systems; artificial intelligence; and human-computer interaction. Proceedings and post-proceedings of referred international conferences in computer science and interdisciplinary fields are featured. These results often precede journal publication and represent the most current research. The principal aim of the IFIP series is to encourage education and the dissemination and exchange of information about all aspects of computing.
Knowledge and Skill Chains in Engineering and Manufacturing : Information Infrastructure in the Era of Global Communications
Explores knowledge and skill chains in engineering and manufacturing in the age of global communications. Information infrastructure involves a range of activities from product planning, engineering, and manufacturing trough transportation, marketing, and repair/upgrade to returns and recycling/disposal. Distinct from the traditional engineering database, life-cycle support information has its own characteristic requirements, -- flexible extensibility, distributed architecture, multiple viewpoints, long-time archiving, and product usage information. Several authors address the architecture of the information infrastructure, its services and its requirements. Other papers focus on the knowledge and skill chains that develop in a variety of situations: the supply chain, the factory floor, the man-system interaction, etc. For each of these, state-of-the-art and state-of-research scenarios for various industrial sectors address both engineering and operations requirements in the current socio-economic environment.
Java Methods for Financial Engineering : Applications in Finance and Investment
This book is structured around the main theories and models used by practitioners to engineer finance and investment tools. The methods developed and implemented in the text are organized as chapters which cover the core areas.
Biometrics, Computer Security Systems and Artificial Intelligence Applications
This book presents the most recent achievements in some fascinating and rapidly developing fields within Computer Science. The scientific works presented in this book have been partitioned into three topical groups: Image Analysis and Biometrics, Computer Security Systems, and Artificial Intelligence and Applications. Image Analysis and Biometrics is the branch of Computer Science dealing with the very difficult task of artificial, visual perception of objects and surroundings, as well as the problems connected with it. Computer Security and Safety is at present a very important and intensively investigated branch of Computer Science because of the menacing activity of hackers and computer viruses.
Beginning C# 2008 : From novice to professional
This book is for anyone who wants to write good C# 2008 code—even if you have never programmed before. Beginning C# 2008 has been written to teach you how to use the C# programming language to solve problems. Christian Gross is dedicated to helping his readers understand every detail of Beginning C# 2008.
Artificial life models in software
Artificial Life Models in Software presents software tools, environments and realities dealing with creation, imitation and analysis of artefactual, virtual and living forms, written by those who personally design and produce software, hardware and art installations in artificial life, simulated complex systems and virtual worlds. This timely volume offers a nearly exhaustive overview and original analysis of major non-profit artificial life software packages. The carefully selected topics include: · simulation of real and imaginary life forms and their evolution · self-organization · emergent behaviours · swarm intelligence · evolutionary robotics · agent-based simulations · adaptive, complex and biologically inspired ecosystems · creative computer art There has long been a need within the academic and research community for an informal introduction and guidance to modern software tools for modelling and simulation of life-like phenomena – Artificial Life Models in Software fills this gap and provides invaluable information to both professional and amateur readers, offering detailed reviews of contemporary software for artificial life.
Artificial Intelligent Techniques for Wireless Communication and Networking
Wireless communication and networking based on AI concepts and techniques are explored in this book, specifically focusing on the current research in the field by highlighting empirical results along with theoretical concepts. The possibility of applying AI mechanisms towards security aspects in the communication domain is elaborated; also explored is the application side of integrated technologies that enhance AI-based innovations, insights, intelligent predictions, cost optimization, inventory management, identification processes, classification mechanisms, cooperative spectrum sensing techniques, ad-hoc network architecture, and protocol and simulation-based environments.
Artificial intelligence for customer relationship management : Solving customer problems
This book describes a number of applications of Artificial Intelligence in the field of Customer Relationship Management with the focus of solving customer problems. We design a system that tries to understand the customer complaint, his mood, and what can be done to resolve an issue with the product or service. To solve a customer problem efficiently, we maintain a dialogue with the customer so that the problem can be clarified and multiple ways to fix it can be sought. We introduce dialogue management based on discourse analysis: a systematic linguistic way to handle the thought process of the author of the content to be delivered. We analyze user sentiments and personal traits to tailor dialogue management to individual customers. We also design a number of dialogue scenarios for CRM with replies following certain patterns and propose virtual and social dialogues for various modalities of communication with a customer.



















