الصفحة 1
الصفحة 1
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Living with Heart Disease

The media are full of terms like angina, heart failure, coronary artery disease, thrombosis, but what do these mean to you? Gerry Coghlan and Clive Handler are experienced heart doctors who have written this book for people who have or might get coronary heart disease.

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Cardiac Mechanotransduction

For about hundred years the investigation of heart physiology has had one central guiding principle, the "law" of Frank and Starling. This connects the return of blood into the heart and the blood pressure with cardiac con­ traction force. The "law" does it in a way that enables the cardiovascular system to react to perturbations without major malfunctions. This book is a compilation of reviews of prominent scientists on this subject. The differ­ ence of the original formulation of the Frank-Starling principle is that mechanotransduction is the central theme that leads the reader through the book. Since the discovery of the "law" the scope of topics related to this subject has broadened enormously, as can be seen easily by glancing at the contents of this book. Mechanotransduction in the heart has many faces that range from molecules to humans and their diseases.

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Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics

In this newly updated second edition of Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics, William B. White, MD, and a panel of highly distinguished clinicians give a critical review of every aspect of the evaluation of high blood pressure. This includes home and ambulatory blood pressure monitoring, the relationship between whole-day blood pressure and the cardiovascular disease process, and the effects of antihypertensive therapies on these blood pressure parameters. World-class contributors describe the significant advances in our understanding of the circadian pathophysiology of cardiovascular disorders and demonstrate that ambulatory blood pressure values are independent predictors of cardiovascular morbidity and mortality.

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Biodiversity and Conservation in Europe

This book brings together a selection of original studies submitted to Biodiversity and Conservation that address biodiversity and conservation in Europe. Europe is certainly the most intensively inventoried region of the world; detailed maps are available for species distributions while action plans are being drawn up for species under threat. At the same time, the wildlife of Europe has been subject to enormous human pressures, with limited ‘wilderness’ sites remaining in most countries. Europe consequently presents a case-study of what the human impact on biodiversity has been, and also what can be done to improve the situation.

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Applied Physiology in Intensive Care Medicine

A series of short papers published in Intensive Care Medicine since 2002 under the heading Physiologic Notes attempts to capture the essence of the physiologic perspectives that underpin both our understanding of disease and response to therapy. Tis present volume combines the complete list of these Physiologic Notes up until July 2006 with the ass o ciated review articles over the same in terval that also address edthese central issues.

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Adrenomedullin in Cardiovascular Disease

Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.

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Autonomous vehicles technological trends

The automotive industry has always been synonymous with research and innovation, but nowadays the industry is adding pressure and is establishing the agenda of the researchers from the field. Visions have been provided, and the hardware and the software exist; the only question remaining is: “who is going to deliver”? To answer this question, we encouraged scientists, researchers, industry specialists, and academics to share their vision of autonomous vehicles. What will the platform look like? What kind of hardware and software is most suitable? Who will make the connection between these two interdependent environments (and how), so that in the end the AI will define the process? These are the pressing issues of the current moment, and this Special Issue will help all those interested in the topic to promote their vision and ideas.

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Advanced manufacturing technology and systems

Advanced manufacturing technology and systems cover a broad scope involving manufacturing processes, machine tool design, system optimization, smart and flexible manufacturing, theoretical study and metrology. This reprint comprises 19 original papers concerning recent advances in the research and development of AMTSs. Specifically, there are many research fields that are covered: machining processes (six papers), micro-/nano-precision fabrication (four papers), and system optimization (eight papers), in addition to one review.

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Low-Cost Country Sourcing : Trends and Implications

Globalization has induced immense cost pressure in most industries. In combination with the economic downturn after the turn of the century, companies are increasingly looking for new ways of reducing costs and increasing shareholder value. From this perspective, low-cost country sourcing has proved to be an effective means to realize cost-saving targets. Although many external key success factors have been identified, relatively little is known about intra-firm factors that can influence the outcome of low-cost country sourcing initiatives.

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Business Education and Emerging Market Economies : Perspectives and Best Practices

Business Education in Emerging Market Economies discusses the impact of business education on emerging markets and explores curricular innovation, pedagogical approaches, and strategic alliances in the context of industrializing economies. Emerging markets consist of eighty percent of the world's population and some 75% of its trade growth in the foreseeable future according to the U.S. Department of Commerce. The potential economic growth of emerging markets has prompted a need to understand the dynamics of these markets, their business institutions, and their educational systems. The pressures of globalization and the recent economic reforms that swept across emerging, developing, and transitioning, economies have had a positive impact on the demand for business education and business knowledge from the developed and industrialized countries. As a result, many methods were developed to transfer know-how from the developed markets including learning through imitation, using western style pedagogical approaches, attending universities in industrialized countries, learning through experience and practice, and using information technology. The conclusion we reach is that business and management education in emerging markets is fast changing the way in which these markets operate and are perceived – business educators are catalysts for greater economic integration.

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Banks and shareholder value : An overview of bank valuation and empirical evidence on shareholder value for banks

In the German banking sector, management is continually increasing its focus on shareholder interests. This can be seen in the ambitious profitability targets set by management in this sector. Some municipalities are also putting increasing pressure on Landesbanks and saving banks, as members of the largest German banking group, to create greater financial value.

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Managing Protected Areas in Central and Eastern Europe Under Climate Change

Addresses the need for sharing knowledge and experience in the field of biodiversity conservation and climate change. There is an urgent need to build capacity in protected areas to monitor, assess, manage and report the effects of climate change and their interaction with other pressures. The contributors identify barriers to the adaptation of conservation management, such as the mismatch between planning reality and the decision context at site level. Short and vivid descriptions of case studies, drawn from investigation areas all over Central and Eastern Europe, illustrate both the local impacts of climate change and their consequences for future management.

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Maintenance of Process Instrumentation in Nuclear Power Plants

The resurgence of the nuclear power industry at a time when the nuclear plant I&C workforce is diminishing due to aging and retirements has been the motivation for writing this book. This book compiles 30 years of practical knowledge gained by the author and his staff in testing the I&C systems of nuclear power plants around the world. It focuses on process temperature and pressure sensors and the verification of these sensors’ calibration and response time.

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Lead-Free Electronic Solders : A Special Issue of the Journal of Materials Science : Materials in Electronics

In the last few decades the effect of lead contamination on human health has received significant attention. Based on such concerns, elimination of lead from ceramic glaze, paint, plumbing etc. has been legislated and implemented. However, until recently, solders used in electronics, based on suitability and knowledge-base developed over a long period of time, remained lead-based. Successive rapid advances in microelectronic devices in recent decades make them obsolete within a very short period after their introduction resulting in significant quantities of electronic wastes in landfills. Leaching of toxic lead from such electronic wastes can result in contamination of the human food chain causing serious health hazards. As a consequence, several European and Pacific Rim countries have passed legislations warranting elimination of lead from electronic solders by fast approaching deadlines. Global economic pressures brought on by such legislations have resulted in a flurry of research activities to find suitable lead-free substitutes for the traditional leaded electronic solders.

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Landscapes Under Pressure : Theory and Practice of Cultural Heritage Research and Preservation

This book investigates the newly emerging scope of interests and project agendas to investigate and preserve cultural landscapes. It presents the historic, archaeological, ethnographic, and environmental traditions of cultural landscape study and the attempts to reconstruct and analyze the complex processes of cultural changes through prehistoric and historic times.The "guiding light" of the book is that the fullest understanding of a cultural landscape will materialize through interdisciplinary cooperation, which should involve an ecological approach with historical ecology as the guiding tool, applied archaeology, and environmental planning.

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Jets From Young Stars III : Numerical MHD and Instabilities

This volume contains the lecture notes of the Third JETSET School on Jets from Young Stars focussing on Numerical MHD and Instabilities. The introductory lectures presented here cover the basic concepts of the numerical methods for the integration of hydrodynamic and magnetohydrodynamic equations and of the applications of these methods to the treatment of the instabilities relevant for the physics of stellar jets. The first part of the book contains an introduction to the finite difference and finite volume methods for computing the solutions of hyperbolic partial differential equations and a discussion of approximate Riemann solvers for both hydrodynamic and magnetohydrodynamic problems. The second part is devoted to the discussion of some of the main instability processes that may take place in stellar jets, namely: the Kelvin-Helmholtz, the radiative shock, the pressure driven and the thermal instabilities.

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Competencies, Higher Education and Career in Japan and the Netherlands

This book investigates how social and cultural factors affect the education, training and career development of graduates of higher education in Japan and the Netherlands. Despite their different historical paths, both countries are now subject to the common pressure of globalization. As a result, the higher education sector in both countries is becoming more universal and available to a larger population, and the economy and society are becoming increasingly knowledge-intensive. The aim of this book is to explore how Dutch and Japanese graduates choose and develop their careers in reference to the above-mentioned challenges. It is based on a unique data set consisting of surveys held among graduates 3 and 8 years after leaving higher education.

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Bulk Metallic Glasses : An Overview

Bulk Metallic Glasses explores an emerging field of materials known as bulk metallic glasses. It summarizes the rapid development of these materials over the last decade and includes documentation on diverse applications of bulk metallic glasses; from structural applications to microcomponents. Some of the applications covered are pressure sensors, microgears for motors, magnetic cores for power supplies, and nano-dies for replacing next generation DVDs. The chapters cover current theories and recent research including an atomistic theory of local topological fluctuations, atomistic simulations, and unique microstructures of these amorphous materials. Other topics include glass formation, glass forming ability, and the underlying mechanisms and physical insights of these criteria. The mechanical deformation of bulk metallic glasses, fatigue, fracture, and corrosion behaviors of these materials are also reviewed.

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Bioactive Heterocycles II

As part of the series Topics in Heterocyclic Chemistry, this volume titled Bio- tive Heterocycles II presents comprehensive and up-to-date reviews on selected topics regarding synthetic as well as naturally occurring bioactive heterocycles. The frst chapter, "High Pressure Synthesis of Heterocycles Related to Bio- tive Molecules" by Kiyoshi Matsumoto, presents a unique high-pressure s- thetic methodology in heterocyclic chemistry. Basic principles and fruitful examples for pericyclic reactions, such as Diels-Alder reactions, 1,3-dipolar reactions, and also for ionic reactions, such as S and addition reactions, are N discussed.

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Atmosphere and Climate : Studies by Occultation Methods

In this book we focus on sensors on Low Earth Orbit (LEO) satellites, which exploit solar, lunar, stellar, GNSS (Global Navi- tion Satellite Systems), and LEO-crosslink signals for observing the Earth's - mosphere and climate. The methods all share the key properties of self-calibration, high accuracy and vertical resolution, global coverage, and (if using radio signals) all-weather ca- bility. The atmospheric parameters obtained extend from the fundamental va- ables temperature, density, pressure and water vapor via trace gases, aerosols and cloud liquid water to ionospheric electron density. Occultation data are therefore of high value in a wide range of fields including climate monitoring and research, atmospheric physics and chemistry, operational meteorology, and ionospheric physics.

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