الصفحة 1
الصفحة 1
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Lymphocyte Signal Transduction

Signal transduction through leukocyte receptors involves a variety of signaling molecules including kinases, phosphatases, adaptor proteins, small GTPases GTP exchange factors, membrane phospholipids as well as others. These signal transducers, regulated by inter- and intra-molecular interactions, as well as by various post-translational modifications, lead to the activation of transcription factors that mediate cellular differentiation and growth, effector cell functions, and apoptotic cell death. Several investigators from various parts of the world convened at the 3rd Lymphocyte Signal Transduction Workshop in Crete, Greece from May 27 to June 1, 2005 to discuss their most recent findings in leukocyte signaling. This volume represents a collection of topics discussed during the conference.

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Chromatin Dynamics in Cellular Function

This volume includes timely reviews of several aspects of chromatin biology written by scientists at the forefront of this rapidly moving field. Topics covered include the structure and function of protein modules within chromatin-remodeling proteins, newly characterized histone modifications (methylation, ubiquitylation) and their functional consequences, transcription and histone dynamics, roles of chromatin remodeling factors in DNA replication and repair, and current models of nucleosome-remodeling mechanisms.

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Chitosan : properties and applications in bioengineering

Presents a review of chitosan, including information regarding its structure, main properties, available sources, extraction, and processing techniques. It presents the different applications of chitosan as a biomaterial in fields such as medicine and the agricultural, cosmetology, pharmaceutical, and food industries to have readers obtain a more technical vision of the current use of this biopolymer.

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Chitin and Chitosan : Properties and Applications

Chitin and Chitosan: Properties and Applications presents a comprehensive review of the isolation, properties and applications of chitin and chitosan. These promising biomaterials have the potential to be broadly applied and there is a growing market for these biopolymers in areas such as medical and pharmaceutical, packaging, agricultural, textile, cosmetics, nanoparticles and more.

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Biopolymers in nutraceuticals and functional foods

Comprehensive book covers new applications of biopolymers in the research and development of industrial scale nutraceutical and functional food grade products.

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Biomedical applications and toxicity of nanomaterials

Covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.

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Biological adhesives

Many plants, animals, and microbes use adhesive polymers and structures to attach to inert substrates, to each other, or to other organisms. This is the first major review that brings together research on many of the well-known biological adhesives. Emphasizing the diversity of biological adhesives and associated adhesion processes, it deals with bacteria, fungi, algae, and marine and terrestrial animals. It bridges a variety of disciplines including biochemistry, molecular biology, biomechanics, bioengineering, microbiology, organism structure and function, and ultrastructure. As we learn more about the molecular and mechanical properties of these adhesives, we begin to understand why they adhere so well and how they develop cohesive strength. With this understanding comes the prospect of developing synthetic or semi-synthetic adhesives with broad applications in areas such as medicine, dentistry, and biotechnology. The book is suitable for both industrial and academic researchers.

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Bioadhesives in Drug Delivery

The topics covered include: Theories and mechanisms of bioadhesion; bioadhesive polymers for drug delivery applications; methods for characterization of bioadhesiveness of drug delivery systems; bioadhesive films and drug delivery applications; bioadhesive nanoparticles; and bioadhesive hydrogels and applications ocular biodhesive drug delivery systems; buccal bioadhesive drug delivery systems; gastrointestinal bioadhesive drug delivery systems ; nasal bioadhesive drug delivery systems; vaginal drug delivery systems; pulmonary bioadhesive drug delivery systems.

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Applications of Mass Spectrometry in Life Safety

MS is continuously developing as one of the most re- able analytical method for elucidating the structure of molecules originating from various biological matrices. The potential of MS for high-sensitive structural a- lyses became unsurpassable after the introduction of electrospray (ESI) and matrix assisted laser/desorption ionization (MALDI) methods, on one hand, and the pos- bility to deduce in detail unknown biopolymer structures by highly accurate mo- cular mass measurement followed by sequencing using dissociation techniques based on multiple stage MS, on the other.

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Alginates in drug delivery

Alginates in Drug Delivery explores the vital precepts, basic and fundamental aspects of alginates in pharmaceutical sciences, biopharmacology, and in the biotechnology industry. The use of natural polymers in healthcare applications over synthetic polymers is becoming more prevalent due to natural polymers’ biocompatibility, biodegradability, economic extraction and ready availability. To fully utilize and harness the potential of alginates, this book presents a thorough understanding of the synthesis, purification, and characterization of alginates and their derivative. This book collects, in a single volume, all relevant information on alginates in health care, including recent advances in the field.

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Advances in artificial intelligence: models, optimization, and machine learning

Contains all the articles accepted and published in the Special Issue “Advances in Artificial Intelligence: Models, Optimization, and Machine Learning” of the MDPI Mathematics journal, which covers a wide range of topics connected to the theory and applications of artificial intelligence and its subfields. These topics include, among others, deep learning and classic machine learning algorithms, neural modelling, architectures and learning algorithms, biologically inspired optimization algorithms, algorithms for autonomous driving, probabilistic models and Bayesian reasoning, intelligent agents and multiagent systems.

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Materials science for dentistry

A standard resource for undergraduate and postgraduate courses in dentistry. It provides fundamental coverage of the materials on which dentistry depends, covering the structure and chemistry that govern the behavior and performance of materials. Particular classes of materials include gypsum, polymers, acrylic, cements, waxes, ceramics and metals. Other chapters review surfaces, corrosion, mixing, casting, cutting and bonding, and mechanical testing. This updated edition, which includes substantial chapters on chemistry, has been extensively revised with new material on temporary restoration resins, hydraulic silicate cements and the practical aspects of wetting surfaces. Mindfully written to provide explanations for behavior, formulation, clinical and laboratory instructions and procedures, there is no comparable resource for researchers, students, teachers and practitioners in the field of dentistry.

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Composite and polymeric materials for dentistry: enhancing antimicrobial and mechanical properties

Focuses on enhancing antimicrobial and mechanical properties of polymeric materials and composites for dentistry. In recent years, special attention has been focused on the possibility of giving materials new or improved properties by the introduction of nano or submicron size additives, fibers or whiskers. Another area of research is the application of antibacterial monomers, which can be copolymerized in resins to kill oral pathogenic microflora. In addition, we are currently looking for new data regarding colonization of dental materials by pathogenic microbes and their influence on the other properties. Further, there are many new commercially available materials which should be investigated to verify their properties, which is important from the point of view of clinical practice. Original new research and reviews related to any of the topics mentioned above indicate the current directions of development of dental materials.

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Biomaterials and engineering for implantology: in medicine and dentistry

Biomaterials are composed of metallic materials, ceramics, polymers, composites and hybrid materials. Biomaterials used in human beings require safety regulations, toxicity, allergic reaction, etc. When used as implantable materials their biological compatibility, biomechanical compatibility, and morphological compatibility must be acessed. This book explores the design and requirements of biomaterials for the use in implantology.

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Biocompatible nanocomposites : From synthesis to applications

Presents a focused overview of biocompatible nanocomposites, emphasizing recent advancements in material design, synthesis techniques, and their expanding applications in biomedicine. It spans key areas such as regenerative medicine, drug delivery, cancer therapy, biosensing, diagnostic imaging, and vaccine delivery —illustrating how these materials are transforming modern healthcare. The book reviews widely used biomaterials including polycaprolactone, bioactive ceramics, and polymer-based hybrids, discussing their roles in cardiovascular, orthopedic, dental, maxillofacial, and ophthalmic applications.

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3D printing in oral & maxillofacial surgery

A comprehensive guide to 3D printing and 3D bioprinting methods and their application in oral and maxillofacial surgeries. Among the 3D printing methods considered are fused deposition modeling, selective laser sintering, photopolymer jetting, powder binder printing, and stereolithography, while the coverage of 3D bioprinting encompasses inkjet, microextrusion, and laser techniques. In each case, the relevance of the technique to oral and maxillofacial surgery is explained. In addition, the available inks and bioinks for 3D printing are reviewed. The roles of soft and hard tissue printing in oral and maxillofacial tissue engineering and the use of 3D printing in multi- and interfacial tissue engineering are then examined in depth. The particular value of 3D printing in the treatment of critically sized defects is discussed separately. Finally, up-to-date information is provided on guided tissue/bone regeneration using 3D printing. The book will be of interest to both oral and maxillofacial surgeons and biomedical engineers.

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Composites for building assembly : connections, members and structures

Pesents buildings developed using modular assembly approaches based on lightweight and corrosion-resistant fiber reinforced polymer (FRP) composites. Construction methods and the choice of building materials offer great opportunities for more productive and environmentally friendly solutions. This book includes valuable experimental data on large-scale structural components (beams, slabs, amd columns), connections (shear connections, wall stud connections, beam-column connections, column-column connections) and structures (composite floor system, structural sandwich assemblies, and full-scale structural demonstrations), supported with detailed numerical modelling and analytical methods.

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Composite materials : sustainable and eco-friendly materials and application

Covers innovations in the field of composite materials with a specific focus on eco-friendly and environmentally sustainable systems. All composite fields are explored, including polymer, metal, and ceramic matrix composites with an emphasis on sourcing raw materials in a sustainable way as well as the development of composite materials for environmental sustainability.

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Civil engineering materials : From theory to practice ; 1st ed.

Presents the state-of-the-art in civil engineering materials, including the fundamental theory of materials needed for civil engineering projects and unique insights from decades of large-scale construction in China. The title includes the latest advances in new materials and techniques for civil engineering, showing the relationship between composition, structure and properties, and covering ultra-high-performance concrete and self-compacting concrete developed in China. This book provides comprehensive coverage of the most commonly used, most advanced materials for use in civil engineering. This volume consists of eight chapters covering the fundamentals of materials, inorganic cementing materials, Portland cement concrete, bricks, blocks and building mortar, metal, wood, asphalt and polymers.

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Alternative concrete - geopolymer concrete : Emerging research and opportunities

Focuses on fly ash-based alkali-activated geopolymer concrete, its production and characteristic properties. The re-use of waste materials and industrial by-products, such as fly ash, is not only economically of interest but also helps to reduce carbon dioxide emissions. The carbon footprint of these materials is much lower than that of concrete using ordinary Portland cement. They thus offer new sustainable solutions to the construction industry.

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