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Manual of Benirschke and Kaufmanns Pathology of the Human Placenta
Benirschke and Kaufmann's Pathology of the Human Placenta has long been regarded as the gold standard in the field. It is comprehensive and thorough and contains the detail necessary for those in the subspecialties of placental, perinatal and pediatric pathology. However, placentas are relatively common specimens and are not examined primarily by specialists in the field, but by general pathologists. Thus, there is a need for a more practical and concise manual that can be used by pathology trainees and generalists in their daily work. Manual of Benirschke and Kaufmann's Pathology of the Human Placenta will fill that need. The Manual is a practical, user-friendly guidebook for the general pathologist and pathologist in training for everyday, bench-side use. Organized in 27 chapters, the book will discuss placental development, general features, approach to the specimen by macroscopic and microscopic evaluation, all aspects of placental abnormalities and lesions, disease processes and the placenta, legal aspects of the placental examination, future directions and much more. The sections on macroscopic and microscopic evaluations feature quick-reference tables that allow the reader to identify abnormalities, learn the situations where they occur, and refer back to the text for in-depth discussions. Each chapter will end with selected readings from Pathology of the Human Placenta for more detailed discussions, classic recommended readings, as well as an up-to-date bibliography of current literature. The manual features over 444 illustrations, more than 100 of them in full-color. A must-have for every pathologist and pathology resident.
Liver and Pancreatic Diseases Management
New therapeutical approaches, advances in oncology and in diagnostic imaging, which reduce the need for invasive techniques and reach an improvement in survival and quality of life in cancer, are considered in this book. Modern literature has been reviewed with special reference to articles of general interest. In the clinical management of patients with liver, bile duct and pancreas diseases, it is important to assess the degree of disturbance and to diagnose the causative insult, and therefore clinical and laboratory methods of assessing each of these pathologies are of high interest. This version is an up-to-date account of diseases of the liver, biliary tract and pancreas, including transplantation, which we trust will be of value for surgeons, physicians and pathologists and also a reference book for medical students.
Les prothèses tricompartimentaires du genou de première intention : Techniques opératoires. Problèmes et solutions = Primary tricompartmental knee replacement : Surgical techniques, problems, and solutions
It seems difficult and presumptuous to want to write a book on total knee replacement. There are many quality works dealing with this subject. The knee prosthesis has, from its origin, particularly in the United States, given rise to considerable studies in all directions: biomechanical, physiological, biological and industrial. Our goal is to offer the youngest a book of simple knowledge without pretension of completeness or prejudice as to long debated subjects (conservation or not of the posterior cruciate ligament, cement or without cement, resurfacing or not of the patella, fixed plate or mobile platform, etc.), and to give practical advice based on our experience. Why limit yourself to first-line tricompartmentals? Because it is the most common solution to the usual degenerative knee problems. In addition, unicompartment and revision prostheses will be the subject of further literature. Everyone knows that to put a knee prosthesis model, and therefore to a system. However, it is important to be able to keep your freedom of analysis in order to maintain your freedom of choice. You have to know how to put on a knee prosthesis without compromise or fanaticism. Convictions are more dangerous enemies of truth than lies. Nietzsche
Les infections intra-abdominales aiguës = Acute intra-abdominal infections
Paradoxically, serious intra-abdominal infections are the forgotten ones in the world of infectious diseases. Paradoxical, because they are very common pathologies, affecting all age groups of the population and often life-threatening; paradoxical, because they concern many medical specialties through intensive care, gastroenterology, hepatology, imaging, infectious diseases, emergencies and surgery. Hence the need, thanks to an interdisciplinary collaboration, to publish a book in French bringing together all infectious abdominal pathologies, thus offering a synthesis of recent data from the literature in this field. This document should allow the various specialties concerned to find updates integrating the latest clinical, diagnostic and therapeutic data. Specialty interns and practitioners in the field will find something to establish an effective and up-to-date strategy for the management of patients with these pathologies, the high incidence of which and the severity of which is too often overlooked, it is important to remember.
Le complicazioni neurologiche in oncologia = Neurological complications in oncology
This volume, both necessary and new in the panorama of Italian medical literature, acknowledges this and presents an updated and complete review of the pathologies of the central and peripheral nervous system associated with tumors and their treatment. The purpose of the volume is to present an integrated approach between specialists that must see the neurologist and the oncologist in dialogue, and able to develop a new super-specialized clinical capacity in neuro-oncology. Many experts have contributed to its preparation by sharing knowledge on topics ranging from metastatic complications, to those of surgical cancer therapy, radio- and chemo-therapy, paraneoplastic syndromes, pain therapy, delirium and the affective alterations associated with the disease. The book is aimed in particular at neurologists, oncologists, palliative care practitioners and surgeons, but it is certainly useful for general practitioners and all operators who are daily involved in the demanding work of taking care of cancer patients.
L’insuffisance rénale aiguë = Acute renal failure
The aim of this book is to make current data from the experimental and clinical literature accessible to readers. More than a thousand articles are published each year on the theme and the authors aim to synthesize this information. These data relate in particular to the identification of early markers of renal dysfunction without which screening, recognition of the main pathophysiological determinants and prevention remain uncertain. This book focuses attention on clinical situations characterized by the renal impact of the main dysfunctions of vital functions, the prognosis of which is worsened by the occurrence of this renal failure. The following will be treated in particular: the renal consequences of oxidative stress, the renal consequences of respiratory dysfunction, cardiac dysfunction, hepatic dysfunction, alterations in hemostasis, septic shock and hemorrhagic shock. Finally, the physiopathological data from experimental models are gradually finding their echo in the clinical field, opening up therapeutic avenues whose recent evaluations will be analyzed.
Classic Papers in Modern Diagnostic Radiology
The subject of diagnostic radiology is now very large and radiology depa- ments are involved in all areas of modern patient care.The defining event in m- ern radiology,and arguably the most significant development in radiology since Wilhelm Röntgen discovered X-rays, was the invention of the CT scanner in the 1970s.The CT scanner introduced modern cross-sectional imaging and also di- tal imaging.We now have MRI and ultrasound and these techniques are replacing many traditional X-ray procedures.The developments in radiology have been the result of a fruitful interaction between the basic sciences, clinical medicine and the manufacturers. This can be seen by looking at the various sources of these publications. Change is produced by the interactions between the various dis- plines. The editors have had a very difficult task in selecting the key discoveries and descriptions.The radiological literature is very large.Medical imaging continues to develop rapidly and these papers are the foundations of our current practice.
Cannabinoids and the brain
Cannabinoids and the Brain gives a comprehensive overview of all the essential literature concerning the endocannabinoid and related systems in the nervous tissue. It is a rapidly expanding research field and the widespread presence of cannabinoids in most physiopathological mechanisms appear to hinder the effort to fully cover the subject. By the end of the book, the reader will have a solid knowledge of the genetics, molecular biology, anatomy, pharmacology, and physiology of the endocannabinoid system and its involvement in neurological and psychiatric disorders, and will eventually discover a natural relationship among marijuana, aspirin, and chili pepper.
Cancer drug safety and public health policy : A changing landscape
Description and analysis of recent developments and current trends in health policy with regard to cancer drug safety. Opens with an overview of pharmacovigilance for cancer blockbuster drugs, covering both general considerations and efforts to develop a structured framework for the identification and reporting of adverse drug reactions (ADRs). A number of important examples of serious ADRs to hematology and oncology drugs are then reviewed, with evaluation of the lessons learned and the policy implications of the ensuing legal cases and their settlements. Further, the difficulty of reporting such blockbuster side effects in the medical literature is explored in an empirical study. Significant advances have been achieved in analytic methods for the identification of ADRs, and here there is a particular focus on the value of optimal discriminant analysis. Finally, the impacts on pharmacovigilance and drug safety of the huge fines paid under the U.S. False Claims Act relating to the defrauding of governmental programs also receive careful attention – these fines are playing an important role in changing the landscape for pharmaceutical safety.
Bionanotechnology : Proteins to Nanodevices
Bionanotechnology is the key integrative technology of the 21st century and aims to use the knowledge, gathered from the natural construction of cellular systems, for the advancement of science and engineering. Investigating the topology and communication processes of cell parts can lead to invention of novel biological devices with exciting applications. Though microscale to nanoscale research offers an excellent space for the development of futuristic technologies, a number of challenges must be overcome. Due to paucity of a dedicated literature on the protein based nanodevices we bring you this monograph that combines collective research works of scientists probing into this fascinating universe of bionanotechnology. The monograph has been written with an aim of surveying engineering design principles of biomolecular nanodevices, prototype nanodevices based on redox proteins, bacteriorhodopsins and natural fibers, and touching upon the future developments in the field.
Biomarkers as targeted herbal drug discovery : A pharmacological approach to nanomedicines
Looks at the applications of biomarkers as important tools for herbal drug discovery, presenting research on phytoconstituents with advanced nanotechnological applications for healthcare benefits. Herbal drug discovery based on biomarkers is an emerging area in complementary and alternative medicine that has tremendous potential in healthcare. Conventional medications have limited efficacy and high toxicity, whereas herbal drugs are said to provide wide structural diversity that is not usually seen with conventional/synthetic drug molecules. Recognition of various herbal constituents, such as terpenoids, fatty acids, flavonoids and steroids, are well explored in the management and treatment of various disorders in this volume. These agents target various biomarkers such as nitric oxide (NO), cytokines, chemokines, adhesion molecules, NF- kβ, lipoxygenase (LOX), and arachidonic acid. Reviews the literature on inflammatory biomarkers in the treatment of diseases Looks at the development of herbal drug discovery based on biomarkers Explores emerging concepts of nanomedicines for herbal drug delivery Takes an interdisciplinary approach, with application to disciplines related to medical, pharmaceutical, biotechnological, Ayurvedic, Unani and biomedical engineering fields
Biology and Ecology of Norway Spruce
This book presents a concise and comprehensive review of the biology, ecology, and management of Norway spruce. It integrates classic and contemporary literature (more than 2000 works cited in the text), highlighting basic research and forestry practices in central and eastern Europe. The topics include anatomy and morphology, physiology and nutrition, reproductive biology and genetics, and ecology. In addition, it examines mycorrhiza, diseases and pests as well as silviculture and wood products. In the light of increasing threats to forest health from air pollution, climate change, and insects and disease, it provides an essential information source to those concerned with the ecology, conservation, and management of the species
Bioactives and pharmacology of medicinal plants : Vol.1
Bioctives and Pharmacology of Medicinal Plants, concisely presents an abundance of important information on the bioactive and pharmacological properties of medicinal plants. It provides valuable comprehensive research and studies on bioactive phytocompounds of over 68 important medicinal plants with beneficial properties. For each species included in the volume, a brief introduction is given along with their bioactive compounds and chemical structures, followed by their chief pharmacological activities that include antiviral, antimicrobial, antioxidant, anti-cancer, anti-inflammatory, antidiabetic, hepatoprotective, nephroprotective, and cardioprotective activities. A review of the published literature on pharmacological activities on each species is included also, providing a thorough resource on each of the plants covered in the volume.
Bioactives and pharmacology of Legumes
A variety of bioactives and therapeutics from the legume family (Fabaceae or Leguminosae) are thoroughly detailed. For each species included in the volume, a brief introduction is given, the plant’s bioactive compounds are listed, and its chemical structures shown, followed by their pharmacological activities. Many of these plants have medicinal activities that include antiviral, antimicrobial, antioxidant, anticancer, anti-inflammatory, and antidiabetic, hepatoprotective, nephroprotective and cardioprotective. The biochemical characteristics of the 37 plants included, such as the type of starch, protein, and fibers, can be exploited as binders, excipients, thickeners, and dispersants in the formulation of various products in the pharmaceutical industry. The published literature on the pharmacological activities on each species is reviewed and presented in a concise and clear manner.
Arts and health promotion : Tools and bridges for practice, research, and social transformation
This book offers an overview of the beautiful, powerful, and dynamic array of opportunities to promote health through the arts from theoretical, methodological, pedagogical, and critical perspectives. This is the first-known text to connect the disparate inter-disciplinary literatures into a coherent volume for health promotion practitioners, researchers, and teachers. It provides a one-stop depository for using the arts as tools for health promotion in many settings and as bridges across communities, cultures, and sectors.
Approaches to the purification, analysis and characterization of antibody-based therapeutics
Provides the interested and informed reader with an overview of current approaches, strategies and considerations relating to the purification, analytics and characterization of therapeutic antibodies and related molecules. While there are obviously other books published in and around this subject area, they seem to be either older (c.a. year 2000 publication date) or are more limited in scope. The book will include an extensive bibliography of the published literature in the respective areas covered. It is not, however, intended to be a how-to methods book.
Aortic dissection and related syndromes
Aortic dissection affects approximately two in ten thousand individuals and can be fatal. This state-of-the-art publication is a result of the combined efforts of participants from the International Registry of Aortic Dissection (IRAD). The book has been divided into sections. Each chapter provides a succinct overview of the current clinical literature and incorporates illustrations for further explanation.
Literature-based Discovery
When Don Swanson hypothesized a connection between Raynaud’s phenomenon and dietary fish oil, the field of literature-based discovery (LBD) was born. During the subsequent two decades a steady stream of researchers have published articles about LBD and the field has made steady progress in laying foundations and creating an identity. LBD is an inherently multi-disciplinary enterprise where collaborations between the information and biomedical sciences are readily encountered. It is the hope and intention that this volume will plant a flag in the ground and inspire new researchers to the LBD challenge.
Classification and Modeling with Linguistic Information Granules : Advanced Approaches to Linguistic Data Mining
Many approaches have already been proposed for classification and modeling in the literature. These approaches are usually based on mathematical mod els. Computer systems can easily handle mathematical models even when they are complicated and nonlinear (e.g., neural networks). On the other hand, it is not always easy for human users to intuitively understand mathe matical models even when they are simple and linear. This is because human information processing is based mainly on linguistic knowledge while com puter systems are designed to handle symbolic and numerical information. A large part of our daily communication is based on words. We learn from various media such as books, newspapers, magazines, TV, and the Inter net through words. We also communicate with others through words. While words play a central role in human information processing, linguistic models are not often used in the fields of classification and modeling. If there is no goal other than the maximization of accuracy in classification and modeling, mathematical models may always be preferred to linguistic models. On the other hand, linguistic models may be chosen if emphasis is placed on interpretability.
Big data analysis of nanoscience bibliometrics, patent, and funding data (2000-2019)
Presents an evaluation of nanotechnologies outputs (academic outputs and patents) and their impact from 2000-2019. The evaluation uses Elsevier’s Scopus (the largest abstract and citation database of peer-reviewed literature), SciVal (a scientific research analysis platform), Funding Institutional (a funding database), and PatentSight (a patent analysis platform). It covers four key topics regarding nanoscience research, including: 1) An overview of nano-related scholarly output, 2) Nanoscience and its contribution to basic science, 3) Nanoscience and its impact on and collaboration with industry partners, and 4) Key factors that promote the development of nanoscience.
