الصفحة 1
الصفحة 1
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Lessons Learned : Risk Management Issues in Genetic Counseling

The only book devoted exclusively to this specialty, Lessons Learned details the risk management issues involved in genetic counseling practice, and offers solid strategies for minimizing the risk of costly, career-damaging malpractice suits. Schmerler clearly identifies areas of practitioner liability and demonstrates how they may be averted, so counselors can better manage their practice while lowering the risk of legal action. Examples drawn from relevant court cases illustrate typical issues in malpractice, negligence, and breach of contract suits. With this in-depth knowledge, readers can refine their goals toward increased self-protection as well as client care.

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Clinical Anesthesia: Near Misses and Lessons Learned

This book serve as either an excellent review for the American Board of Anesthesiology’s oral exam or as an easy and practical way for the reader to gain familiarity with unexpected problems in clinical anesthesia.

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Cancer drug safety and public health policy : A changing landscape

Description and analysis of recent developments and current trends in health policy with regard to cancer drug safety. Opens with an overview of pharmacovigilance for cancer blockbuster drugs, covering both general considerations and efforts to develop a structured framework for the identification and reporting of adverse drug reactions (ADRs). A number of important examples of serious ADRs to hematology and oncology drugs are then reviewed, with evaluation of the lessons learned and the policy implications of the ensuing legal cases and their settlements. Further, the difficulty of reporting such blockbuster side effects in the medical literature is explored in an empirical study. Significant advances have been achieved in analytic methods for the identification of ADRs, and here there is a particular focus on the value of optimal discriminant analysis. Finally, the impacts on pharmacovigilance and drug safety of the huge fines paid under the U.S. False Claims Act relating to the defrauding of governmental programs also receive careful attention – these fines are playing an important role in changing the landscape for pharmaceutical safety.

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Angiogenesis in Inflammation : Mechanisms and Clinical Correlates

This volume relates the lessons learned from tumour biology applied to inflammation. This issue of Angiogenesis in Inflammation: Mechanisms and Clinical Correlates develops current knowledge on the mechanisms at the molecular and cellular levels as they relate to inflammation, including acute and chronic inflammation, neurogenic initiation, and the role of the multiple cellular components that comprise inflammation: granulocytes, macrophages, fibroblasts, dendritic cells and lymphocytes. This is related to inflammatory disease: not only the familiar angiogenesis dependent diseases of rheumatoid arthritis and psoriasis, but also loci such as the lung, gastric ulcers, the eye with uveitis, wound healing and periodontal disease and their therapy, how this knowledge may be used in the discovery of novel therapeutics. The volume brings together experts in each of these fields to link the molecular and cellular processes in angiogenesis to those of inflammation and disease, culminating in a discourse on areas for future therapies.

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Competition Authorities in South Eastern Europe : Building Institutions in Emerging Markets

Provides answers to key open questions concerning competition policy in emerging economies, with a focus on South Eastern Europe. The contributions address two major issues. One is the design of competition policy and the national competition authorities that enforce it, including the topics of competition advocacy and state aid control; the other is the use of economic methods in competition law enforcement, especially in the cases of relevant market definition and merger control. Many lessons learned in the countries of South Eastern Europe can be applied to the emerging markets of other regions. As such, the findings presented here will be highly relevant for officials and staff at national competition authorities, advisers to legislators shaping national competition policy, competition law professionals, and university students alike.

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Managed Software Evolution

This open access book presents the outcomes of the “Design for Future – Managed Software Evolution” .The different lifecycles of software and hardware platforms lead to interoperability problems in such systems. Instead of separating the development, adaptation and evolution of software and its platforms, as well as aspects like operation, monitoring and maintenance, they should all be integrated into one overarching process. Accordingly, the book is split into three major parts, the first of which includes an introduction to the nature of software evolution, followed by an overview of the specific challenges and a general introduction to the case studies used in the project. The second part of the book consists of the main chapters on knowledge carrying software, and cover tacit knowledge in software evolution, continuous design decision support, model-based round-trip engineering for software product lines, performance analysis strategies, maintaining security in software evolution, learning from evolution for evolution, and formal verification of evolutionary changes. In turn, the last part of the book presents key findings and spin-offs. The individual chapters there describe various case studies, along with their benefits, deliverables and the respective lessons learned. An overview of future research topics rounds out the coverage.

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Best practices in software measurement : How to use metrics to improve project and process performance

Not everything that counts can be counted. Not everything that is counted counts. Albert Einstein This is a book about software measurement from the practitioner’s point of view and it is a book for practitioners. Software measurement needs a lot of practical guidance to build upon experiences and to avoid repeating errors. This book t- gets exactly this need, namely to share experiences in a constructive way that can be followed. It tries to summarize experiences and knowledge about software measurement so that it is applicable and repeatable. It extracts experiences and lessons learned from the narrow context of the specific industrial situation, thus facilitating transfer to other contexts. Software measurement is not at a standstill. With the speed software engine- ing is evolving, software measurement has to keep pace. While the underlying theory and basic principles remain invariant in the true sense (after all, they are not specific to software engineering), the application of measurement to specific contexts and situations is continuously extended. The book thus serves as a ref- ence on these invariant principles as well as a practical guidance on how to make software measurement a success.

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Advances in Big Data Analytics : Theory, Algorithms and Practices

Provides a comprehensive and cutting-edge study on big data analytics, based on the research findings and applications developed by the author and his colleagues in related areas. It addresses the concepts of big data analytics and/or data science, multi-criteria optimization for learning, expert and rule-based data analysis, support vector machines for classification, feature selection, data stream analysis, learning analysis, sentiment analysis, link analysis, and evaluation analysis. The book also explores lessons learned in applying big data to business, engineering and healthcare. Lastly, it addresses the advanced topic of intelligence-quotient (IQ) tests for artificial intelligence.

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Managing Global Innovation : Uncovering the Secrets of Future Competitiveness

"Managing Global Innovation is a rich compendium of new concepts of global R&D, enlivened by 18 excellent best-in-class case studies. What is especially impressive, the authors bridge seamlessly theoretical and practical issues about how companies create, transform and implement new technology in an expanding marketplace. This will be intriguing to both the industry and the academic world. The lessons learned are invaluable. The book is a real tour de force, probably destined to become a standard in this field for some time to come." Professor Jeff Huang, Harvard University "This excellent book demonstrates how the dynamics of innovation and creativity can be mastered. Important reading for senior management and a must for R&D leaders."

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Knowledge Management and Management Learning : Extending the Horizons of Knowledge-Based Management

The book begins with an extended introduction and theoretical framework. Contributing authors have written chapters that add to both the framework and the practical consequences of knowledge management. These chapters suggest many lessons learned that will find considerable use in practice. Some of these chapters include an investigation of the "do’s and don’ts" virtual learning based on real-life cases, the use of design teams for group learning, the role of language and the creation of common ground between company and client, culture as a dynamic and non-linear constructed concept, innovation and knowledge management and more. The book offers an exceptional range of contributions within a developing paradigm. Within this context, the book illustrates why and how of knowledge management is important for companies.

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Competition Policies in Emerging Economies : Lessons and Challenges from Central America and Mexico

Do small developing economies, or SDEs, need a specific competition policy to create competitive markets? Against the backdrop of globalization, protectionist policies that promote state ownership and heavy regulation of key industries are proving increasingly ineffective for driving growth. Countries around the world are instituting reforms to promote competition and business creation, yet the economic and political concentration of power, feeble judicial systems, and the scarcity of human and financial resources pose special challenges to SDEs. Competition Policies in Emerging Economies features an in-depth analysis of two strategic industries — telecommunications and banking — in several Central American nations which sheds light on the dynamics of the transition to deregulation and trade liberalization. Examining the lessons learned from these experiences and presenting discussion of political, legal, economic, financial, cultural, and organizational issues, the book provides unique perspectives on competition policy and economic development.

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Management of Intentional and Accidental Water Pollution

The goals of the workshop included a discussion of the state of the science in identification of new research and approaches for water pollution events and communication of the management of water pollution and sustainability of water resources. Critical to management of accidental and intentional pollution events is the assessment of the risk, an understanding of the hazards and lessons learned from events which may lead to preventative management and control strategies. Public health protection will ultimately be improved by the ability to develop management frameworks which are flexible and adaptable to the specific region, country or watershed problems and concerns and allow for prioritization in the decision making. The integration of scientific information regarding the types of hazards the environmental fate of the chemical/biological, exposure pathways and human and ecosystem impacts may be implemented from both a qualitative or descriptive approach or using a more classical quantitative risk assessment paradigm. Thus the frameworks for assessing the risk and managing the risk may be seen as preventive, early warning and responsive.

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Learning in Modern International Society : On the Cognitive Problem Solving Abilities of Political Actors

Claudia Hofmann engages in a theoretical modelling of international learning processes and the substantiation of this model through three cases from international politics. She answers two questions: How may international actors learn as a collective? And how may the lessons learned influence actor behaviour and problem solving processes? As a foundation for answering these questions she examines the nature of actor behaviour within a social international system and integrates the diffusion of norms and values among macro-level actors.

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Community Quality-of-Life Indicators : Best Cases VIII

Offers critical insights into the thriving international field of community indicators, incorporating the experiences of government leaders, philanthropic professionals, community planners and a wide range of academic disciplines. It illuminates the important role of community indicators in diverse settings and the rationale for the development and implementation of these innovative projects.  details many of the practical “how to” aspects of the field as well as lessons learned from implementing indicators in practice. The case studies included here also demonstrate how, using a variety of data applications, leaders of today are monitoring and measuring progress and communities are empowered to make sustainable improvements in their wellbeing.

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Chernobyl - What Have We Learned? : The Successes and Failures to Mitigate Water Contamination Over 20 Years

Twenty million people have been exposed to Chernobyl radionuclides through the Dnieper River aquatic pathways. This book presents a 20-year historical overview and comprehensive study results of the aquatic environment affected by the 1986 Chernobyl nuclear accident. During this time, many water quality management practices and countermeasures were enacted. The book presents in-depth analyses of these water remediation actions, using current science and mathematical modeling, and discusses why some were successful, but many others failed. The chapter entitled Where Do We Go From Here? incorporates a comprehensive discussion of the planned New Safe Confinement (NSC) structure to cover the Chernobyl plant. The book closes with a summary and conclusions drawn from these analyses, making it a valuable reference tool for the future. This book will be of interest to engineers, scientists, decision-makers, and those involved in radiation protection and radioecology, environmental protection and risk assessment, water remediation and mitigation measures, and radioactive waste disposal. In addition, the detailed, almost day-to-day, emergency responses to the Chernobyl accident described in this book will also be useful to people developing emergency and long-term responses to accidental or intentional (by terrorists) releases of radionuclides, toxic chemicals and biological agents.

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Acid in the Environment : Lessons Learned and Future Prospects

This book is the result of a conference held biannually at the Goodwin-Niering Center for Conservation Biology and Environmental Studies at Connecticut College.is a collection of essays that blends the research findings and the policy analyses of individuals from different academic disciplines with the positions advanced by representatives of NGOs. Acid in the Environment: Lessons Learned and Future Prospects presents a broad approach to the study of acid deposition, exposing readers with a scientific background to significant policy issues and those with a policy orientation to important ecological impacts. The book raises important questions that will serve as a springboard for discussion between diverse groups of teachers and students, concerned citizens and legislators, and scientists and policy makers.

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