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الصفحة 1
Advances in pharmacokinetics and pharmacodynamics
Provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using PBPK modeling (Chapter 2). Chapters 3 and 4 describe the recent development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) models and their applications to pharmacokinetic data. The pharmacodynamics section focuses on PK/PD modeling. Chapter 5 provides an overview of PK/PD modeling and simulation in clinical practice and studies. Chapter 6 deals with the subject/physiology variability issue encountered in PK/PD studies, while Chapter 7 reviews the influence of clinical pharmacology in the modernization of drug development and regulation. This book is an essential reference for pharmaceutical scientists.
Complex Analysis with Applications to Number Theory
The book discusses major topics in complex analysis with applications to number theory.It 's including the theory of several finitely and infinitely complex variables, hyperbolic geometry, two- and three-manifolds, and number theory. In addition to solved examples and problems, the book covers most topics of current interest, such as Cauchy theorems, Picard’s theorems, Riemann–Zeta function, Dirichlet theorem, Gamma function, and harmonic functions.
Beginning XSLT 2.0 : From novice to professional
This followup to Jeni Tennison's Beginning XSLT has been updated to accomodate the revised XSLT standard. Part one of this book introduces XML and XSLT at a comfortable pace, and gradually demonstrates techniques for generating HTML (plus other formats), from XML. In part two, Tennison applies theory to real-life XSLT capabilities—including generating graphics. Each chapter includes step-by-step examples (with code available online), plus review questions at the end, to help you grasp the discussed features. In fact, all of the examples and exercises revolve around an interesting common theme: making TV listings available online. This book lives up to its name, and will definitely take you from a novice to a professional, in no time!
Anomaly Detection : Techniques and Applications
When information in the data warehouse is processed, it follows a definite pattern. An unexpected deviation in the data pattern from the usual behavior is called an anomaly. The anomaly in the data is also referred to as noise, outlier, spammer, deviations, novelties and exceptions. Identification of the rare items, events, observations, patterns which raise suspension by differing significantly from the majority of data is called anomaly detection. With progress in the technologies and the widespread use of data for the purpose for business the increase in the spams faced by the individuals and the companies are increasing day by day. This noisy data has boomed as a major problem in various areas such as Internet of Things, web service, Machine Learning, Artificial Intelligence, Deep learning, Image Processing, Cloud Computing, Audio processing, Video Processing, VoIP, Data Science, Wireless Sensor etc. Identifying the anomaly data and filtering them before processing is a major challenge for the data analyst. This anomaly is unavoidable in all areas of research. This book covers the techniques and algorithms for detecting the deviated data.
Algorithms in Invariant Theory
The book of Sturmfels is both an easy-to-read textbook for invariant theory and a challenging research monograph that introduces a new approach to the algorithmic side of invariant theory. The Groebner bases method is the main tool by which the central problems in invariant theory become amenable to algorithmic solutions.
Algorithms and Programming : Problems and Solutions
This book containing classical and well-known problems supplemented by clear and in-depth explanations. The material covered includes such topics as combinatorics, sorting, searching, queues, grammar and parsing, selected well-known algorithms and much more.
Algorithms – ESA 2005 ; 13th Annual European Symposium, Palma de Mallorca, Spain, October 3-6, 2005, Proceedings
This volume contains the 75 contributed papers and the abstracts of the threeinvited lectures presented at the 13th Annual European Symposium on Algo-rithms (ESA 2005), held in Spain, 2005. respectively.Papers were solicited in all areas of algorithmic research, including but notlimited to algorithmic aspects of networks, approximation and on-line algo-rithms, computational biology, computational geometry, computational financeand algorithmic game theory, data structures, database and information re-trieval, external memory algorithms, graph algorithms, graph drawing, machinelearning, mobile computing, pattern matching and data compression, quantumcomputing, and randomized algorithms. The algorithms could be sequential,distributed, or parallel. Submissions were especially encouraged in the area ofmathematical programming and operations research, including combinatorialoptimization, integer programming, polyhedral combinatorics, and semidefiniteprogramming.Each extended abstract was submitted to one of the two tracks.
A Classical Introduction to Cryptography : Applications for Communications Security
This advanced-level textbook covers conventional cryptographic primitives and cryptanalysis of these primitives; basic algebra and number theory for cryptologists; public key cryptography and cryptanalysis of these schemes; and other cryptographic protocols, e.g. secret sharing, zero-knowledge proofs and undeniable signature schemes.
Material Modeling in Finite Element Analysis
Presents some specific problems including the metal-forming process, combustion room, Mullins effect of rubber tires, viscoelasticity of liver soft tissues, small punch test, tunnel excavation, slope stability, concrete slump test, orthodontic wire, and piezoelectric microaccelerometer.
Composites for building assembly : connections, members and structures
Pesents buildings developed using modular assembly approaches based on lightweight and corrosion-resistant fiber reinforced polymer (FRP) composites. Construction methods and the choice of building materials offer great opportunities for more productive and environmentally friendly solutions. This book includes valuable experimental data on large-scale structural components (beams, slabs, amd columns), connections (shear connections, wall stud connections, beam-column connections, column-column connections) and structures (composite floor system, structural sandwich assemblies, and full-scale structural demonstrations), supported with detailed numerical modelling and analytical methods.
Aging, shaking, and cracking of infrastructures : From mechanics to concrete dams and nuclear structures
Focuses on the safety assessment of existing structures subjected to multi-hazard scenarios through advanced numerical methods. Whereas the focus is on concrete dams and nuclear containment structures, the presented methodologies can also be applied to other large-scale ones. This book is composed of seven sections: Fundamentals: theoretical coverage of solid mechnics, plasticity, fracture mechanics, creep, / seismology, dynamic analysis, probability and statistics / Damage: that can affect concrete structures, such as cracking of concrete, AAR, chloride ingress, and rebar corrosion, / Finite Element: formulation for both linear and nonlinear analysis including stress, heat and fracture mechanics, / Engineering Models: for soil/fluid-structure interaction, uncertainty quantification, probablilistic and random finite element analysis, machine learning, performance based earthquake engineering, ground motion intensity measures, seismic hazard analysis, capacity/fragility functions and damage indeces, / Applications to dams through potential failure mode analyses, risk-informed decision making, deterministic and probabilistic examples, / Applications to nuclear structures through modeling issues, aging management programs, critical review of some analyses, / Other applications and case studies: massive RC structures and bridges, detailed assessment of a nuclear containment structure evaluation for license renewal.
Advances in Mechanics of Materials for Environmental and Civil Engineering
Deals with both mathematical modeling and experimental studies related to systems relevant for various civil engineering fields. The book addresses several key topics, including artificial intelligence applied to the control and monitoring of construction site personnel, finite element models for endplate beam-to-column connections under various load conditions, random functionally graded micropolar beams, and many others. The book explores the design and study of microstructures aimed at increasing the toughness and durability of novel materials in building and construction, based also on the re-utilization of residues and wastes of metallurgical industry produces.
Advanced structural mechanics : An introduction to continuum mechanics and structural mechanics
In recent years an increasing emphasis has been placed on numerically based methods of structural analysis. This has been reflected in the production of structural mechanics texts that are orientated towards particular numerical methodologies, especially the finite element method. Whilst this approach serves the needs of potential research' engineers, a concentration on the numerical analysis aspects of structural mechanics is of less relevance to professional' engineers, who are likely to be concerned with the use and interpretation of numerical analyses, but not in the development of the methodologies.
A Generalization of Bohr-Mollerup's Theorem for Higher Order Convex Functions
This book develops a far-reaching generalization of Bohr-Mollerup's theorem to higher order convex functions, along lines initiated by Wolfgang Krull, Roger Webster, and some others but going considerably further than past work. In particular, this generalization shows using elementary techniques that a very rich spectrum of functions satisfy analogues of several classical properties of the gamma function, including Bohr-Mollerup's theorem itself, Euler's reflection formula, Gauss' multiplication theorem, Stirling's formula, and Weierstrass' canonical factorization.
Lean Brain Management : More Success and Efficiency by Saving Intelligence
Intelligence is wasted on problems that themselves have been caused by an excess of intelligence. Lean Brain Management strives toward uncompromising Lean Brain Quality. Lean Brain stands for consistent economization of intelligence in all realms of life: Intelligent systems will only be operated by unskilled workers. Education, universities, and schools would become obsolete. A week of training would be enough for virtually any job. ("You are now the physician for the measles in the State of Ohio. In response to phone calls, send this prescription.") Lean Brain is not aimed at dumbing down! Lean Brain can survive on just a very small amount of central intelligence. Potential savings amount to trillions! This is demonstrated using Germany as an example. With this book, Dueck presents a radical suggestion for world improvement. The desire to laugh infinitely about it will eventually segue into a collective rude awakening. The book contains concrete advice for managers to economize on intelligence, and is thus--in keeping with the theme--written in an easy-to-read fashion.
Aalto in Detail : A Catalogue of Components
Celebrates the rich detail in the work of Aino, Elissa, and Alvar Aalto. Every support, railing, and handle is the result of intensive formal and functional research. The authors document 50 Aalto buildings - some well-known and others less so - and arrange their photographs by component into 20 chapters. The result is a rich photographic record that will serve as a source of inspiration for every architect. From door handles to skylights: Aalto's infinite wealth of components Inspiring documentation with 400 systematically arranged photos Unconventionally detailed solutions with special attention paid to technical feasibility
Mathematical Control Theory : An Introduction
Mathematical Control Theory: An Introduction presents, in a mathematically precise manner, a unified introduction to deterministic control theory. With the exception of a few more advanced concepts required for the final part of the book, the presentation requires only a knowledge of basic facts from linear algebra, differential equations, and calculus. In addition to classical concepts and ideas, the author covers the stabilization of nonlinear systems using topological methods, realization theory for nonlinear systems, impulsive control and positive systems, the control of rigid bodies, the stabilization of infinite dimensional systems, and the solution of minimum energy problems.
Matematica e cultura 2008 = mathematics and culture 2008
In this new book, the tenth of the series that began in Venice with the meetings "Mathematics and culture" that many have tried to imitate, we talk about all this and among others Simon Singh (author of the best seller "The last theorem di Fermat "), in her third presence in Venice, and Siobhan Roberts (author of" The king of infinite space. History of the man who saved geometry "). Venice bridge between mathematics and culture.
Mass Terms : Some Philosophical Problems
MASS TERMS, COUNT TERMS, AND SORTAL TERMS Central examples of mass terms are easy to come by. 'Water', 'smoke', 'gold', etc. , differ in their syntactic, semantic, and pragmatic properties from count terms such as 'man', 'star', 'wastebasket', etc. Syntactically, it seems, mass terms do, but singular count terms do not, admit the quantifier phrases 'much', 'an amount of', 'a little', etc. The typical indefinite article for them is 'some' (unstressed)!, and this article cannot be used with singular count terms. Count terms, but not mass terms, use the quantifiers 'each', 'every', 'some', 'few', 'many'; and they use 'a(n)' as the indefinite article. They can, unlike the mass terms, take numerals as prefixes.
Magnetism in the Solid State : An Introduction
Presents a phenomenological approach to the field of solid state magnetism. After introducing the basic concepts from statistical thermodynamics and electronic structure theory, the first part discusses the standard models for localized moments (Weiss, Heisenberg) and delocalized moments (Stoner). This is followed by a chapter about exchange and correlation in metals, again considering the results for the localized and delocalized limit. The book ends with a chapter about spin fluctuations, which are introduced as an alternative to the finite temperature Stoner theory. A useful reference work for researchers, this book will also be a valuable accompaniment to graduate courses on magnetism and magnetic materials.
