الصفحة 48
الصفحة 48
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Acute Promyelocytic Leukemia : Molecular Genetics, Mouse Models and Targeted Therapy

Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models and culminating in the development of targeted therapy.

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Active Conceptual Modeling of Learning : Next Generation Learning-Base System Development

This volume contains a collection of the papers presented during the 1st International ACM-L Workshop, which was held on November 8, 2006 during the 25th International Conference on Conceptual Modeling, ER 2006, held November 6–9,2006, in Tucson, Arizona, plus several invited papers.These papers plus the invited papers represent the current thinking in conceptual modeling research, The active model can only be realized through technology integration (e.g., AI, software engineering, information technology,cognitive science, art and sciences, philosophy, etc.)

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Acoustics and Hearing

When one listens to music at home, one would like to have an acoustic impression close to that of being in the concert hall. Until recently this meant elaborate multi-channelled sound systems with 5 or more speakers. But head-related stereophony achieves the surround-sound effect in living rooms with only two loudspeakers. By virtue of their slight directivity as well as an electronic filter the limitations previously common to two-speaker systems can be overcome and this holds for any arbitrary two-channel recording. The book also investigates the question of how a wide and diffuse sound image can arise in concert halls and shows that the quality of concert halls decisively depends on diffuse sound images arising in the onset of reverberation. For this purpose a strong onset of reverberation is modified in an anechoic chamber by electroacoustic means.

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Acid Rain - Deposition to Recovery

Acid rain is still with us. Although it is a problem that people have worked diligently to solve, there are still many problem areas throughout the world. In reality the focus of acid rain research has shifted, and this book adds new vision to the topic. It contains papers, selected from Acid Rain 2005, the 7th International Conference on Acid Deposition, that take a broad perspective of the issues, emphasizing a number of themes: - the emission, concentration and deposition of pollutants / - nitrogen and trace elements in ecosystems and their effects on forests, water and soil / - studies of material damage and recovery - critical loads / The book is aimed at scientists and researchers who are working in the area of acid rain and its effects, and on nutrient cycling. This latest research will be of value to those concerned with the mitigation of acid rain effects.

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Accounting and auditing small and medium-sized practices : Transformative capabilities in a rapidly changing society

Addresses recent trends, developments, and future of accounting and auditing of small and medium-sized practices (AASMPs) in the public and private sectors.the book has three main objectives: firstly, to provide an analysis of how different societal trends, including digitalization, impact AASMPs and what role education and training play in proactive adaptation to those trends; secondly, to outline major scenarios for global AASMP development by 2035; and thirdly, to offer a conceptual framework for better understanding of AASMPs' dynamic and transformative capabilities that are necessary to create sustained competitive advantage in a rapidly changing society. beyond presenting a conceptual framework, this book also offers a discussion of future scenarios for AASMPs' development and their role in the global economic development.

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Account management strategies in B2B sales : Generating customer value and building sustainable business relationships - methodology, processes, tools

Provides employees and managers in sales with a clearly defined process for building sustainable business relationships along the account journey. Using a structured method, you will learn how to set yourself up for success right from the start, increase your competitiveness, increase market share and generate more sales.

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Accessing Multilingual Information Repositories ; 6th Workshop of the Cross-Language Evaluation Forum, CLEF 2005, Vienna, Austria, 21-23 September, 2005, Revised Selected Papers

The sixth campaign of the Cross Language Evaluation Forum (CLEF) for European languages was held from January to September 2005. CLEF is by now an established international evaluation initiative and 74 groups from all over the world submitted results for one or more of the different evaluation tracks in 2005, compared with 54 groups in 2004. There were eight distinct evaluation tracks, designed to test the performance of a wide range of systems for multilingual information access. Full details regarding the design of the tracks, the methodologies used for evaluation, and the results obtained by the participants can be found in the different sections of these proceedings.

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Accessing and Sharing the Benefits of the Genomics Revolution

This edited volume explores the legal, economic and political context for the debate about intellectual property rights for traditional knowledge and genetic resources and critically analyses the theory and practice of access and benefits sharing efforts around the world. The book also investigates the current flashpoints—the David and Goliath battle between Monsanto and Percy Schmeiser over farmers’ rights; the dispute over coexistence of GM and organic production; and the ownership and control of human genetic materials stored in human gene banks around the world.

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Access to online resources : A guide for the modern librarian

The book offers a concise guide for librarians, helping them understand the challenges, processes and technologies involved in managing access to online resources. After an introduction the book presents cases of general authentication and authorisation. It helps readers understand web based authentication and provides the fundamentals of IP address recognition in an easy to understand manner. A special chapter is dedicated to Security Assertion Markup Language (SAML), followed by an overview of the key concepts of OpenID Connect. The book concludes with basic troubleshooting guidelines and recommendations for further assistance. Librarians will benefit from this quick and easy read, which demystifies the technologies used, features real-life scenarios, and explains how to competently employ authentication and access management.

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Abuse of Dominant Position : New Interpretation, New Enforcement Mechanisms?

As part of its review of competition law that started in the late 1990s, the European Commission proposes to revise its interpretation and application of the Treaty’s prohibition of abuses of dominant positions. Also, it has instigated a debate about the promotion of private enforcement of EC competition law. The chapters in this volume critically appraise the Commission’s proposals, including the most recent ones. The authors also highlight the repercussions of the proposed ‘more economic approach’ to abuses of dominant positions on private litigants’ opportunities to bring damages actions in national courts for such abuses.

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Absolute Essentials of Business Ethics

Explores practical applications of how business ethics impacts working lives, allowing readers to reflect on their own moral compass through the use of ethical dilemmas. Highlighting the extensive breadth of issues related to business ethics, the authors introduce and analyze ethical and unethical behaviors of firms through numerous real -life examples including Patagonia, Costco, LVMH, Bill Gates, Muhummad Yunus, Enron, WorldCom, Samsung, Purdue Pharma, Vale Mining and the COVID-19 crisis.

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A Twenty-First Century Guide to Aldersonian Marketing Thought

The book has three major themes: glimpses into the kind of interesting character he was, key excerpts from his writings, and commentaries on the perceived current relevance of Aldersonian marketing thought. … this book is an excellent vehicle for educating people on a guru, influencer, theoretician, practitioner and leader in the development of marketing theory. … this is a valuable resource for anyone desiring to know about marketing theory and to understand the genesis of a number of concepts currently found in today’s marketing textbooks.

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A Successful Transformation? : Restructuring of the Czech Automobile Industry

This book investigates the complex processes of the post-1990 transformation in the Czech automotive industry and its selective integration in the West European automobile manufacturing system. The post-1990 restructuring of the Czech automotive industry is analyzed in the context of its pre-1990 development and in the context of the Central and East European automobile industry as a whole. Specifically, the book examines the development and post-1990 restructuring of the Czech passenger car industry, the components industry and truck manufacturing. Major topics covered include the development of the Czech automotive industry before 1990, the detailed case study of Škoda Auto, the effects of the post-1990 privatization in the Czech automotive industry, the role and effects of foreign direct investment during the post-1990 restructuring, the restructuring of the Czech truck industry, and the rapid development of the automotive components manufacturing.

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A primer on theoretical soil mechanics

A Primer to Theoretical Soil Mechanics is about adapting continuum mechanics to granular materials. The field of continuum mechanics offers many fruitful concepts and methods, however there is declining interest in the field due to its complex and fragmented nature. This book's purpose is therefore to facilitate the understanding of the theoretical principles of soil mechanics, as well as introducing the new theory of barodesy.

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A practical guide on behaviour change support for self-managing chronic disease

Developed under the auspices of the Train4Health project, funded by the Erasmus+ program of the European Union, the book contains six chapters written by international contributors from different disciplines. Chapter one introduces the competencies necessary for delivering effective behavior change support, based on an established program of work, and related learning outcomes. The four following chapters describe how these competencies can be acquired, focusing on concepts and theories, assessing self-management behaviors, implementing change strategies and person-centered communication, using a practical approach.

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A journey of embedded and cyber-physical systems : Essays dedicated to Peter Marwedel on the occasion of his 70th birthday

This book celebrates Professor Peter Marwedel's outstanding achievements in compilers, embedded systems, and cyber-physical systems. The contributions in the book summarize the content of invited lectures given at the workshop “Embedded Systems” held at the Technical University Dortmund in early July 2019 in honor of Professor Marwedel's seventieth birthday.

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A High-Performance Logical Framework -- All About Maude : How to Specify, Program, and Verify Systems in Rewriting Logic

This book gives a comprehensive account of Maude, a language and system based on rewriting logic. Many examples are used throughout the book to illustrate the main ideas and features of Maude, and its many possible uses. Maude modules are rewrite theories. Computation with such modules is - cient deduction by rewriting. Because of its logical basis and its initial model semantics,aMaude module defines a precise mathematical model.This means that Maude and its formal tool environment can be used in three, mutually reinforcing ways: • as a declarative programming language; • as an executable formal specification language; and • as a formal verification system. Maude’s rewriting logic is simple, yet very expressive. This gives Maude good representational capabilities as a semantic framework to formally represent a wide range of systems, including models of concurrency, distributed al- rithms, network protocols, semantics of programming languages, and models of cell biology. Rewriting logic is also an expressive universal logic,making Maude a fiexible logical framework in which many difierent logics and - ference systems can be represented and mechanized. This makes Maude a useful metatool to build many other tools, including those in its own formal tool environment. Thanks to the logic’s simplicity and the use of advanced semi-compilation techniques, Maude has a high-performance implementation, making it competitive with other declarative programming languages.

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A healthcare professionals training system

The Objective Structured Clinical Examination (OSCE) is a type of examination often used in health sciences. It is designed to test clinical skill performance and competence in a range of skills. It is a practical, real-world approach to learning and assessment. Comprises a circuit of short (5-10 minutes) stations, in which each candidate is examined on a one-to-one basis with one or two impartial examiner(s) and patients who are either real or simulated (actors or electronic patient simulators). Each station has a different examiner; in comparison, the traditional method of clinical examination is when a candidate is assigned to an examiner for the entire examination.

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A Graph-Theoretic Approach to Enterprise Network Dynamics

This monograph treats the application of numerous graph-theoretic algorithms to a comprehensive analysis of dynamic enterprise networks. Network dynamics analysis yields valuable information about network performance, efficiency, fault prediction, cost optimization, indicators and warnings.

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A Concise Guide to Endodontic Procedures

A concise up-to-date resource that covers a wide range of endodontic procedures, including non-surgical root canal therapy, surgical root canal therapy, trauma care and the management of fractured teeth, apexification, apexogenesis, revascularization, regeneration, Cvek partial pulpotomy, root canal retreatment, and periapical surgery.

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