تحسين النتائح
ترتيب حسب
من
الى
الصفحة 4
الصفحة 4
Analysis of Waiting-Time Data in Health Services Research
Analysis of Waiting-Time Data in Health Services Research asks critical questions linking waiting times to health care outcomes. Generously illustrated with charts and tables, the book places this type of data collection, analysis, and reporting firmly in the context of health services research, the study of outcomes of health care delivery to a population.
Analysis file of drug-induced lung injury : expert opinion for analysis of big data
Describes the pathologic conditions of drug-induced lung injuries, monitoring strategies, and guides on how to interpret the evidence. It also dives into particular drugs that caused the disorder, such as EGFR inhibitors, anti-EGFR antibodies, mTOR inhibitors, proteasome inhibitors, immune checkpoint inhibitors, neoangiogenesis inhibitors, and other molecular targeted drugs. It outlines the analysis and interpretation of the post-marketing survey on surveillance of each drug for inducing pulmonary lesions presenting diffuse haziness. The data and analysis from this survey are valuable since a guideline is yet to be established due to limited clinical evidence and cases. As new drugs are developed, establishing treatment and event management is crucial.
Analysing Ecological Data
This book provides a practical introduction to analysing ecological data using real data sets collected as part of postgraduate ecological studies or research projects. The first part of the book gives a largely non-mathematical introduction to data exploration, univariate methods (including GAM and mixed modelling techniques), multivariate analysis, time series analysis (e.g. common trends) and spatial statistics. The second part provides 17 case studies, mainly written together with biologists who attended courses given by the first authors. The case studies include topics ranging from terrestrial ecology to marine biology.
An introduction to generative drug discovery
Describes the state‑of‑the‑art methods and applications for de novo design of drug candidates using generative chemistry models as well as the ethical aspects of this technology. It will provide a foundation for those new to the field as well as those that may already have some experience of its utility. With contributions from scientists in both academia and industry ‘Introduction to Generative Drug Discovery’ may represent one of the earliest if not the first book to focus on this topic.
Amazing numbers in biology
With hundreds of tables and over 10,000 entries anyone who works or studies in the life sciences or those with a curious mind will find exact answers to many questions requiring comparative data. This book is a clearly laid out presentation of the plain facts of life from all areas of biology. None of those figures or superlatives that might seem exotic to the layman is left out. Biology comes alive by this comprehensive references work.
AI in disease detection : Advancements and applications
Discusses the integration of artificial intelligence to revolutionize disease detection approaches, with case studies of AI in disease detection as well as insight into the opportunities and challenges of AI in healthcare as a whole. The book explores a wide range of individual AI components such as computer vision, natural language processing, and machine learning as well as the development and implementation of AI systems for efficient practices in data collection, model training, and clinical validation.
Age-related changes of the human Eye
In Age-Related Changes of the Human Eye, the authors review all aspects of human eye aging. In addition to descriptions of age-related changes in almost all the structures of the human eyes, the authors also include interesting accounts of personal experiments and data.
Advances in Targeted Cancer Therapy
This volume is the first book to cover the general topic of targeted cancer therapy. It presents a range of targets such as tumor angiogenesis, cell cycle control and cell signalling, COX-2, apoptosis/cell survival, invasion and metastasis and approaches like kinase inhibitors, antisense, and antibody-based therapeutics. The emphasis is on preclinical development, including target validation, development of biomarkers, strategies for combination approaches, and development of resistance. The particular challenges involved in translating these data to clinical application are discussed.
Advances in pharmacokinetics and pharmacodynamics
Provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using PBPK modeling (Chapter 2). Chapters 3 and 4 describe the recent development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) models and their applications to pharmacokinetic data. The pharmacodynamics section focuses on PK/PD modeling. Chapter 5 provides an overview of PK/PD modeling and simulation in clinical practice and studies. Chapter 6 deals with the subject/physiology variability issue encountered in PK/PD studies, while Chapter 7 reviews the influence of clinical pharmacology in the modernization of drug development and regulation. This book is an essential reference for pharmaceutical scientists.
Advances in cognitive neurodynamics ICCN 2007; Proceedings of the International conference on cognitive neurodynamics - 2007
Contains the Proceedings of the 1st International Conference on Cognitive Neurodynamics held in Shanghai, November 17-21, 2007. The participants were treated to an exciting and stimulating conference that left everyone with an enthusiastic vision for the future of the field. The latest important progress was covered by 13 mini-symposia including: Models of Mental Disorders; Cognitive Machines; Dynamics in learning and memory; Central nervous system synchronization; Neuroinformatics; Cognitive Computational Modeling of Human Language Processing; Cognitive Neurodynamics of Attention; Bottom-Up and Top-Down; Brain Networks; From Anatomy to Dynamics; Translational Cognitive Neuroimaging; K-sets; Theory and Applications; Advanced Signal Processing Techniques for Brain Data Analysis; Visual cortex: information processing and dynamics; Dynamics of Firing Patterns and Synchronization in Neuronal Systems.
Adaptive dynamic programming for chemotherapy drug delivery
Focuses on the practical application of Adaptive Dynamic Programming (ADP) in chemotherapy drug delivery, taking into account clinical variables and real-time data. ADP's ability to adapt to changing conditions and make optimal decisions in complex and uncertain situations makes it a valuable tool in addressing pressing challenges in healthcare and other fields. As optimization technology evolves, we can expect to see even more sophisticated and powerful solutions emerge.
Acute Endocrinology : From Cause to Consequence
The integration of endocrinology in critical care medicine has led to new experimental and clinical data on the complex endocrine and metabolic derangements accompanying non-endocrine severe illnesses. The joining of these two disciplines has generated important novel insights with significant clinical implications. Acute Endocrinology: From Cause to Consequence compiles these new findings into an important and highly relevant new resource.
Abl Family Kinases in Development and Disease
Abl Family Kinases in Development and Disease provides an overview of the functions of Abl family kinases in Development and Disease. This new title discusses the biochemical, genetic, and cell biological data that elucidate the cellular roles for these kinases in these processes.
A Changing World : Challenges for Landscape Research
Written primarily for researchers and advanced students in environmental and social sciences, this latest book in Springer’s Landscape Series looks at some of the emerging fields and new challenges in landscape research. These include: the role of value systems in perceiving, appreciating, and managing landscapes the ‘space’ and ‘place’ concept in landscape research GIS and remote sensing techniques for gathering and processing spatially and temporally explicit land cover, vegetation, and land use data methods of landscape history landscape genetics and genetic methods to test landscape connectivity and dispersal of plant and animal species
25 Years of P53 Research
Communication, awareness and access to information: Given the complexity of the field and the fact that data pertaining to each particular aspects of p53 biology or deregulation are scattered in many different publications, it is extremely difficult to access the full scale of relevant information of any specific p53-related topic. This book may help in this task by putting into perspective both general considerations on the p53 pathway and more specific information on various aspects of p53. In the longer term, however, open access to p53 complexity will require the development of knowledge bases accessible through the web and using simple navigation tools to guide users towards the specific information they need. Several efforts are currently being developed in that direction. They need to be strenghtened and better integrated within the rapidly growing galaxy of web-based information sources on molecular and individual variations in cancer. 2. Reference functional assays and structural analysis: Given the huge diversity of cellular and animal models for wild-type or mutant p53 functions, it will be important to set up standard, universally accepted assays to measure critical p53 protein functions.
Linked Democracy : Foundations, Tools, and Applications
This book shows the factors linking information flow, social intelligence, rights management and modelling with epistemic democracy, offering licensed linked data along with information about the rights involved. This model of democracy for the web of data brings new challenges for the social organisation of knowledge, collective innovation, and the coordination of actions. Licensed linked data, licensed linguistic linked data, right expression languages, semantic web regulatory models, electronic institutions, artificial socio-cognitive systems are examples of regulatory and institutional design (regulations by design). The web has been massively populated with both data and services, and semantically structured data, the linked data cloud, facilitates and fosters human-machine interaction. Linked data aims to create ecosystems to make it possible to browse, discover, exploit and reuse data sets for applications. Rights Expression Languages semi-automatically regulate the use and reuse of content.
Big Data and Global Trade Law
Explores the relevance of global trade law for data, big data and cross-border data flows. Contributing authors from different disciplines including law, economics and political science analyze developments at the World Trade Organization and in preferential trade venues by asking what future-oriented models for data governance are available and viable in the area of trade law and policy. The collection paints the broad picture of the interaction between digital technologies and trade regulation as well as provides in-depth analyses of critical to the data-driven economy issues, such as privacy and AI, and different countries' perspectives.
Leveraging Data Science for Global Health
Explores ways to leverage information technology and machine learning to combat disease and promote health, especially in resource-constrained settings. It focuses on digital disease surveillance through the application of machine learning to non-traditional data sources.
Blockchain, artificial intelligence, and the internet of things : Possibilities and opportunities
Provides basic concepts and deep knowledge about various security mechanisms that can be implemented in IoT through Blockchain technology. This book aids readers in gaining insight and knowledge about providing security and solutions to different challenges in IoT using Blockchain technology. This book primarily focuses on challenges to addressing the integration of the IoT with Blockchain with respect to potential benefits for IoT. This book gives descriptive analysis of Blockchain integrated with IoT applications and platforms for the development of IoT solutions along with possible topologies to that integration. Several application examples are included in a variety of industries / Provides the latest on secure IIoT communication using Blockchain technology for Industry 4.0 / Includes updates on using Blockchain technology in secure vehicular communication (VANET), healthcare, retail, and gaming / Provides the latest on secure IIoT communication using Blockchain technology for Industry 4.0
Artificial intelligence in the financial services industry
Today, the financial services sector is facing a period of rapid disruption and innovation, and artificial intelligence (AI) is at the heart of these changes. Artificial intelligence can be used to gather enormous amounts of data, detect abnormalities, and solve complex problems. Financial institutions are already experimenting extensively with AI strategies to enhance and streamline financial institutions, BSA and AML compliance, CRA requirements, fraud detection, and real estate valuations, all while reducing cost levels. This book looks at how artificial intelligence is affecting the financial services industry.
